Compounds > substance p, sar(9)-met(o2)(11)-
Page last updated: 2024-09-05

substance p, sar(9)-met(o2)(11)- and atropine

substance p, sar(9)-met(o2)(11)- has been researched along with atropine in 7 studies

Compound Research Comparison

Studies
(substance p, sar(9)-met(o2)(11)-)		Trials
(substance p, sar(9)-met(o2)(11)-)		Recent Studies (post-2010)
(substance p, sar(9)-met(o2)(11)-)		Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010) (atropine)
1510626,7111,2591,697

Protein Interaction Comparison

ProteinTaxonomysubstance p, sar(9)-met(o2)(11)- (IC50)atropine (IC50)
cystic fibrosis transmembrane conductance regulatorHomo sapiens (human)21.41
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.012
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.0067
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0007
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.0009
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.0015
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.0021
Alpha-1D adrenergic receptorHomo sapiens (human)1.354
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.012

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Barbier, A; Doutremepuich, JD; Lacheretz, F; Vilain, P1
Giachetti, A; Maggi, CA; Santicioli, P; Zagorodnyuk, V1
Bertrand, C; Geppetti, P; Graf, PD; Nadel, JA1
Condon, RE; Sarna, SK; Tsukamoto, M1
Kondo, A; Ohmura, M; Saito, M1
Amato, A; Mulè, F; Serio, R1

Other Studies

7 other study(ies) available for substance p, sar(9)-met(o2)(11)- and atropine

ArticleYear
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
Effect of substance P and Sar9Met(O2)11-substance P on cutaneous capillary permeability in guinea pig skin.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1992, Volume: 5, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Atropine; Capillary Permeability; Coloring Agents; Fluoroacetates; Guinea Pigs; Injections, Intradermal; Male; Norepinephrine; Oligopeptides; Organic Chemicals; Promethazine; Skin; Substance P

1992
Evidence that tachykinin NK1 and NK2 receptors mediate non-adrenergic non-cholinergic excitation and contraction in the circular muscle of guinea-pig duodenum.
    British journal of pharmacology, 1995, Volume: 115, Issue:2

    Topics: Action Potentials; Adenosine Diphosphate; Animals; Apamin; Arginine; Atropine; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Guanethidine; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; Nifedipine; Nitroarginine; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Suramin; Thionucleotides

1995
Capsaicin increases airflow resistance in guinea pigs in vivo by activating both NK2 and NK1 tachykinin receptors.
    The American review of respiratory disease, 1993, Volume: 148, Issue:4 Pt 1

    Topics: Airway Resistance; Animals; Atropine; Benzamides; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine; Male; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P

1993
A novel motility effect of tachykinins in normal and inflamed colon.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: Animals; Atropine; Colon; Dogs; Female; Hexamethonium; Inflammation; Infusions, Intra-Arterial; Male; Muscle Contraction; Muscle, Smooth; Myoelectric Complex, Migrating; Receptors, Tachykinin; Substance P; Tetrodotoxin

1997
Response of isolated human neurogenic bladders to tachykinins.
    Urologia internationalis, 1997, Volume: 59, Issue:4

    Topics: Adolescent; Atropine; Child; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Meningomyelocele; Muscle Contraction; Neurokinin A; Neurokinin B; Sacrococcygeal Region; Substance P; Tachykinins; Urinary Bladder, Neurogenic

1997
Role for NK(1) and NK(2) receptors in the motor activity in mouse colon.
    European journal of pharmacology, 2007, Sep-10, Volume: 570, Issue:1-3

    Topics: Animals; Atropine; Colon; Electric Stimulation; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Muscle Contraction; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Sodium Channel Blockers; Substance P; Tetrodotoxin

2007