Page last updated: 2024-09-03

substance p, methyl ester- and 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one

substance p, methyl ester- has been researched along with 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one in 4 studies

Compound Research Comparison

Studies
(substance p, methyl ester-)
Trials
(substance p, methyl ester-)
Recent Studies (post-2010)
(substance p, methyl ester-)
Studies
(7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)
Trials
(7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)
Recent Studies (post-2010) (7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)
3501217016

Protein Interaction Comparison

ProteinTaxonomysubstance p, methyl ester- (IC50)7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one (IC50)
Substance-P receptorHomo sapiens (human)0.03
Substance-P receptorCavia porcellus (domestic guinea pig)0.032

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Longmore, J; Main, MJ; Razzaque, Z; Seabrook, GR1
Barr, AJ; Watson, SP1
Fox, AJ; Naeem, S; Patel, IA; Urbán, L; Walpole, C1
Erin, N; Nizam, E1

Other Studies

4 other study(ies) available for substance p, methyl ester- and 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one

ArticleYear
Differences in the effects of tachykinin NK1 receptor antagonists: neuronal versus smooth muscle tissues.
    European journal of pharmacology, 1993, Nov-30, Volume: 250, Issue:1

    Topics: Animals; Biphenyl Compounds; Electrophysiology; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Isoindoles; Locus Coeruleus; Male; Muscle, Smooth; Myenteric Plexus; Neurokinin-1 Receptor Antagonists; Neurons; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Substance P; Superior Cervical Ganglion; Urinary Bladder

1993
Non-peptide antagonists, CP-96,345 and RP 67580, distinguish species variants in tachykinin NK1 receptors.
    British journal of pharmacology, 1993, Volume: 108, Issue:1

    Topics: Animals; Binding Sites; Biphenyl Compounds; Carbachol; Cell Line; Female; Guinea Pigs; Humans; Hydrolysis; Ileum; Indoles; Inositol Phosphates; Isoindoles; Male; Muscle, Smooth; Neurokinin B; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tumor Cells, Cultured

1993
Receptors mediating tachykinin-evoked depolarisations of neurons in the neonatal rat spinal cord.
    Acta biologica Hungarica, 1996, Volume: 47, Issue:1-4

    Topics: Animals; Animals, Newborn; Biphenyl Compounds; Evoked Potentials; In Vitro Techniques; Indoles; Isoindoles; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neurons; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Spinal Cord; Substance P; Tachykinins

1996
Differential consequences of neurokinin receptor 1 and 2 antagonists in metastatic breast carcinoma cells; Effects independent of Substance P.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Animals; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Chemokine CXCL2; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Isoindoles; Mice; Neoplasm Metastasis; Neurokinin-1 Receptor Antagonists; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P

2018