Compounds > substance p, gly(12)-
Page last updated: 2024-09-04

substance p, gly(12)- and substance p

substance p, gly(12)- has been researched along with substance p in 8 studies

Compound Research Comparison

Studies
(substance p, gly(12)-)		Trials
(substance p, gly(12)-)		Recent Studies (post-2010)
(substance p, gly(12)-)		Studies
(substance p)		Trials
(substance p)		Recent Studies (post-2010) (substance p)
80017,2892772,010

Protein Interaction Comparison

ProteinTaxonomysubstance p, gly(12)- (IC50)substance p (IC50)
Substance-P receptorRattus norvegicus (Norway rat)0.0005
Substance-K receptorRattus norvegicus (Norway rat)0.2
Substance-K receptorHomo sapiens (human)0.2455
Substance-P receptorHomo sapiens (human)0.0011
Neuromedin-K receptorHomo sapiens (human)0.125
Substance-K receptorMesocricetus auratus (golden hamster)0.148

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's7 (87.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erion, MD; Gilligan, JP; Jeng, AY; Lovato, SJ; Wong, M1
Kream, RM; Marchand, JE1
Kream, RM; Marchand, JE; Shimonaka, H1
Clancy, AN; el-Bermani, W; Kream, RM; Macrides, F; Mancuso, R; Schoenfeld, TA1
Jeng, AY; Wong, M1
Fisher, CE; Krause, JE; Leeman, SE; Murphy, JR; Sutherland, JA; vanderSpek, JC1
Chou, M; Erion, MD; Fujimoto, RA; Jeng, AY; Tan, J1
Caldwell, RB; Caldwell, RW; Feng, J; Girard, PR; Huang, J; Li, C; May, SW; Moore, AB; Oldham, CD; Scott, RO; Wang, WZ1

Other Studies

8 other study(ies) available for substance p, gly(12)- and substance p

ArticleYear
A radioimmunoassay for measuring alpha-amidating enzyme activity.
    Analytical biochemistry, 1990, Volume: 185, Issue:2

    Topics: Animals; Carcinoma; Culture Media; Goats; Kinetics; Male; Mixed Function Oxygenases; Multienzyme Complexes; Oxidoreductases Acting on CH-NH Group Donors; Pituitary Gland; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P; Thyroid Neoplasms; Tissue Extracts; Tumor Cells, Cultured

1990
The glycine-extended SP precursor, SP-G, is normally expressed in SP-containing neurons.
    Annals of the New York Academy of Sciences, 1991, Volume: 632

    Topics: Animals; Brain; Brain Chemistry; Brain Stem; Chromatography, High Pressure Liquid; Colchicine; Hypothalamus; Immunohistochemistry; Prosencephalon; Radioimmunoassay; Reference Values; Spinal Cord; Substance P

1991
Biochemical characterization and anatomical distribution of a major form of unamidated precursor of substance P in rat brain.
    Brain research, 1991, Dec-20, Volume: 567, Issue:2

    Topics: Amino Acid Sequence; Animals; Brain; Chromatography, High Pressure Liquid; Colchicine; Immunohistochemistry; Male; Molecular Sequence Data; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P

1991
Precursor forms of substance P (SP) in nervous tissue: detection with antisera to SP, SP-Gly, and SP-Gly-Lys.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:14

    Topics: Animals; Brain Stem; Chromatography, High Pressure Liquid; Cricetinae; Immune Sera; Male; Mesocricetus; Protein Precursors; Radioimmunoassay; Spinal Cord; Substance P

1985
Posttranslational modification of glycine-extended substance P by an alpha-amidating enzyme in cultured sensory neurons of dorsal root ganglia.
    Journal of neuroscience research, 1994, Volume: 37, Issue:1

    Topics: Animals; Animals, Newborn; Ascorbic Acid; Cells, Cultured; Chelating Agents; Copper; Ditiocarb; Ganglia, Spinal; Mixed Function Oxygenases; Multienzyme Complexes; Nerve Tissue Proteins; Neurons, Afferent; Protein Precursors; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Substance P

1994
Genetic construction and properties of a diphtheria toxin-related substance P fusion protein: in vitro destruction of cells bearing substance P receptors.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jul-09, Volume: 93, Issue:14

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Survival; CHO Cells; Cloning, Molecular; Cricetinae; Diphtheria Toxin; Escherichia coli; Humans; Kinetics; Molecular Sequence Data; Rats; Receptors, Neurokinin-1; Recombinant Fusion Proteins; Substance P; Transfection; Tumor Cells, Cultured

1996
Suppression of substance P biosynthesis in sensory neurons of dorsal root ganglion by prodrug esters of potent peptidylglycine alpha-amidating monooxygenase inhibitors.
    The Journal of biological chemistry, 1997, Jun-06, Volume: 272, Issue:23

    Topics: Animals; Animals, Newborn; Ascorbic Acid; Carcinoma, Medullary; Cells, Cultured; Culture Media, Conditioned; Enzyme Inhibitors; Esters; Ganglia, Spinal; Gene Expression; Homocysteine; Indicators and Reagents; Mixed Function Oxygenases; Molecular Structure; Multienzyme Complexes; Neurons, Afferent; Prodrugs; Protein Precursors; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Substance P; Thyroid Neoplasms; Tumor Cells, Cultured

1997
Amidative peptide processing and vascular function.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Amino Acid Sequence; Animals; Aorta, Thoracic; Cattle; Cells, Cultured; Endothelium, Vascular; In Vitro Techniques; Kinetics; Male; Mixed Function Oxygenases; Molecular Sequence Data; Multienzyme Complexes; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Peptide Fragments; Rats; Rats, Sprague-Dawley; Substance P

1997