Page last updated: 2024-09-04

substance p, gly(12)- and colchicine

substance p, gly(12)- has been researched along with colchicine in 2 studies

*Colchicine: A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE). [MeSH]

*Colchicine: A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE). [MeSH]

Compound Research Comparison

Studies
(substance p, gly(12)-)
Trials
(substance p, gly(12)-)
Recent Studies (post-2010)
(substance p, gly(12)-)
Studies
(colchicine)
Trials
(colchicine)
Recent Studies (post-2010) (colchicine)
80015,4724042,974

Protein Interaction Comparison

ProteinTaxonomysubstance p, gly(12)- (IC50)colchicine (IC50)
Tubulin alpha-1A chainSus scrofa (pig)3.7639
Tubulin beta chainSus scrofa (pig)3.8663
Tubulin beta-4A chainHomo sapiens (human)2.4334
Tubulin beta chainHomo sapiens (human)2.7244
Tubulin alpha-3C chainHomo sapiens (human)2.4334
Serine/threonine-protein kinase pim-1Homo sapiens (human)4.3
Tubulin alpha-1B chainHomo sapiens (human)2.4334
Tubulin alpha-4A chainHomo sapiens (human)2.4334
Tubulin beta-4B chainHomo sapiens (human)2.4334
Vesicular acetylcholine transporterTetronarce californica (Pacific electric ray)2.62
Tubulin beta-3 chainHomo sapiens (human)2.4334
Tubulin beta-2A chainHomo sapiens (human)2.4334
Tubulin beta-8 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainBos taurus (cattle)2.8255
Tubulin alpha-3E chainHomo sapiens (human)2.4334
Tubulin alpha-1A chainHomo sapiens (human)2.4334
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.0611
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.1553
Tubulin alpha-1C chainHomo sapiens (human)2.4334
Tubulin beta-6 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainHomo sapiens (human)2.4334
Tubulin beta-1 chainHomo sapiens (human)2.4334

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kream, RM; Marchand, JE1
Kream, RM; Marchand, JE; Shimonaka, H1

Other Studies

2 other study(ies) available for substance p, gly(12)- and colchicine

ArticleYear
The glycine-extended SP precursor, SP-G, is normally expressed in SP-containing neurons.
    Annals of the New York Academy of Sciences, 1991, Volume: 632

    Topics: Animals; Brain; Brain Chemistry; Brain Stem; Chromatography, High Pressure Liquid; Colchicine; Hypothalamus; Immunohistochemistry; Prosencephalon; Radioimmunoassay; Reference Values; Spinal Cord; Substance P

1991
Biochemical characterization and anatomical distribution of a major form of unamidated precursor of substance P in rat brain.
    Brain research, 1991, Dec-20, Volume: 567, Issue:2

    Topics: Amino Acid Sequence; Animals; Brain; Chromatography, High Pressure Liquid; Colchicine; Immunohistochemistry; Male; Molecular Sequence Data; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P

1991