Page last updated: 2024-09-04

substance p (5-11) and naloxone

substance p (5-11) has been researched along with naloxone in 4 studies

Compound Research Comparison

Studies
(substance p (5-11))
Trials
(substance p (5-11))
Recent Studies (post-2010)
(substance p (5-11))
Studies
(naloxone)
Trials
(naloxone)
Recent Studies (post-2010) (naloxone)
260020,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomysubstance p (5-11) (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lei, SZ; Lipkowski, AW; Wilcox, GL1
Del Rio, J; Naranjo, JR1
Nieber, K; Oehme, P1
Costa, E; Del Río, J; Naranjo, JR; Yang, HY1

Other Studies

4 other study(ies) available for substance p (5-11) and naloxone

ArticleYear
Opioid and neurokinin activities of substance P fragments and their analogs.
    European journal of pharmacology, 1991, Feb-07, Volume: 193, Issue:2

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Neurokinin A; Neurokinin B; Peptide Fragments; Premedication; Substance P

1991
Locomotor activation induced in rodent by substance P and analogues. Blockade of the effect of substance P by met-enkephalin antiserum.
    Neuropharmacology, 1984, Volume: 23, Issue:10

    Topics: Animals; Enkephalin, Methionine; Immune Sera; Male; Mice; Mice, Inbred ICR; Motor Activity; Naloxone; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Substance P

1984
[Differences in activity between substance P and substance P-heptapeptide as studied on the phenomenon of "gut dependence" in rats (author's transl)].
    Die Pharmazie, 1982, Volume: 37, Issue:5

    Topics: Animals; Humans; Ileum; In Vitro Techniques; Male; Morphine Dependence; Muscle Contraction; Muscle, Smooth; Naloxone; Peptide Fragments; Rats; Substance P

1982
Substance P-induced release of Met5-enkephalin from striatal and periaqueductal gray slices.
    Brain research, 1983, Nov-21, Volume: 279, Issue:1-2

    Topics: Animals; Arginine Vasopressin; Bombesin; Corpus Striatum; Dose-Response Relationship, Drug; Enkephalin, Methionine; Male; Naloxone; Neurotensin; Nociceptors; Peptide Fragments; Periaqueductal Gray; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sensory Thresholds; Substance P

1983