Page last updated: 2024-09-05

substance p (1-4) and substance p

substance p (1-4) has been researched along with substance p in 16 studies

Compound Research Comparison

Studies
(substance p (1-4))
Trials
(substance p (1-4))
Recent Studies (post-2010)
(substance p (1-4))
Studies
(substance p)
Trials
(substance p)
Recent Studies (post-2010) (substance p)
180017,2892772,010
18001302
18002300
180085012

Protein Interaction Comparison

ProteinTaxonomysubstance p (1-4) (IC50)substance p (IC50)
Substance-P receptorRattus norvegicus (Norway rat)0.0005
Substance-K receptorRattus norvegicus (Norway rat)0.2
Substance-K receptorHomo sapiens (human)0.2455
Substance-P receptorHomo sapiens (human)0.0011
Neuromedin-K receptorHomo sapiens (human)0.125
Substance-K receptorMesocricetus auratus (golden hamster)0.148

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199012 (75.00)18.7374
1990's3 (18.75)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bury, RW; Mashford, ML1
Ber, E; Cascieri, MA; Cheung, AH; Fong, TM; Huang, RR; Sadowski, S; Strader, CD1
Cordova, A; Hecht, K; Hilse, H; Jumatov, J; Oehme, P; Repke, H1
Nieber, K; Oehme, P1
Binert, M; Gorizontova, MP; Odariuk, Iu1
Arefolov, VA; Nieber, K; Oehme, P; Valdman, AV1
Arefolov, VA; Malikova, LA; Nieber, K; Oehme, P; Val'dman, AV1
Minenko, A; Oehme, P; Tjulkova, E1
Bertilsson, L; Brodin, E; Mårtensson, B; Nyberg, S; Toresson, G1
Gorizontova, MP1
Hilse, H; Oehme, P; Shekhter, AB; Solov'eva, AI; Spevak, SE1
Gyllenhammar, H; Hafström, I; Palmblad, J; Ringertz, B1
Kotovych, G; Otter, A; Stewart, JM1
Sakurada, C; Sakurada, S; Sakurada, T; Tan-No, K; Watanabe, C1
Carter, JD; Devlin, RB; Oortgiesen, M; Simon, SA; Veronesi, B1
Berthou, C; Bourquard, P; Eveillard, JR; Hardy, E; Ianotto, JC; Le Gall, C; Morice, P; Ngo-Sack, F; Ugo, V1

Other Studies

16 other study(ies) available for substance p (1-4) and substance p

ArticleYear
Biological activity of C-terminal partial sequences of substance P.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:6

    Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, Thin Layer; Countercurrent Distribution; Dogs; Ear; Guinea Pigs; Hindlimb; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Rabbits; Regional Blood Flow; Substance P; Veins

1976
Determination of the amino acid residues in substance P conferring selectivity and specificity for the rat neurokinin receptors.
    Molecular pharmacology, 1992, Volume: 41, Issue:6

    Topics: Amino Acid Sequence; Animals; Brain Chemistry; CHO Cells; Cloning, Molecular; Cricetinae; DNA; Eledoisin; Kassinin; Kinetics; Molecular Sequence Data; Peptide Fragments; Polymerase Chain Reaction; Rats; Receptors, Neurokinin-2; Receptors, Neurotransmitter; RNA, Messenger; Stomach; Substance P; Substrate Specificity; Tachykinins

1992
Prevention of stress-induced involution of the thymus in rats by substance P (SP1-11) and its N-terminal fragment SP1-4.
    Die Pharmazie, 1987, Volume: 42, Issue:1

    Topics: Adrenal Glands; Animals; Atrophy; Male; Oligopeptides; Organ Size; Peptide Fragments; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Psychological; Substance P; Thymus Gland

1987
Effect of substance P (SP) and the N-terminal SP-analogue SP (1-4) on the pre- and postsynaptic transmitter release in rat adrenal gland slices.
    Biomedica biochimica acta, 1987, Volume: 46, Issue:1

    Topics: Acetylcholine; Adrenal Glands; Animals; Electric Stimulation; In Vitro Techniques; Male; Neurotransmitter Agents; Nicotine; Norepinephrine; Oligopeptides; Peptide Fragments; Rats; Rats, Inbred Strains; Substance P

1987
[Effect of the N-terminal fragment of substance P on the microcirculatory system].
    Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 105, Issue:4

    Topics: Animals; Male; Microcirculation; Peptide Fragments; Rats; Rats, Inbred Strains; Stress, Physiological; Substance P

1988
Effect of the N-terminal tetrapeptide of substance P SP (1-4) and tuftsin on the pre- and postsynaptic transmitter outflow in rat adrenal gland slices.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:7

    Topics: Acetylcholine; Adrenal Glands; Animals; Electric Stimulation; In Vitro Techniques; Neurotransmitter Agents; Nicotine; Peptide Fragments; Rats; Substance P; Tuftsin

1988
[Effect of the N-terminal fragment of substance P1-4 on the somatic manifestations of the stress reaction and on the catecholamine content of the adrenals in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 107, Issue:2

    Topics: Adrenal Glands; Animals; Catecholamines; Drug Evaluation, Preclinical; Histocytochemistry; Male; Microscopy, Electron; Peptide Fragments; Rats; Restraint, Physical; Stress, Physiological; Substance P; Time Factors

1989
Effects of substance P (SP) and the N-terminal SP-analogue SP (1-4) on inositol phospholipids in rat adrenal medulla slices.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:9

    Topics: Adrenal Medulla; Animals; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Male; Peptide Fragments; Phosphatidylinositols; Phospholipids; Rats; Substance P; Sugar Phosphates

1988
Fluoxetine treatment of depression. Clinical effects, drug concentrations and monoamine metabolites and N-terminally extended substance P in cerebrospinal fluid.
    Acta psychiatrica Scandinavica, 1989, Volume: 79, Issue:6

    Topics: Adult; Aged; Depressive Disorder; Female; Fluoxetine; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Peptide Fragments; Substance P

1989
[Effect of substance P and its N-terminal fragment on the components of the normal microcirculatory system and under stress].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1989, Volume: 75, Issue:5

    Topics: Animals; Cell Membrane Permeability; Dose-Response Relationship, Drug; Male; Mast Cells; Mesenteric Veins; Peptide Fragments; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Psychological; Substance P; Veins; Venules

1989
[Characteristics of the course of the wound process in spontaneously hypertensive rats and the effect of morphine, substance P and its fragment SP1-4].
    Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 107, Issue:6

    Topics: Animals; Blood Pressure; Drug Synergism; Male; Morphine; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Opioid; Skin; Substance P; Time Factors; Wound Healing

1989
Substance P activates and modulates neutrophil oxidative metabolism and aggregation.
    The Journal of rheumatology, 1989, Volume: 16, Issue:8

    Topics: Cell Aggregation; Dose-Response Relationship, Drug; Glucuronidase; Humans; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Oxygen; Peptide Fragments; Substance P

1989
One- and two-dimensional 1H NMR study of the substance P fragment ARG-PRO-Lys-Pro.
    Journal of biomolecular structure & dynamics, 1986, Volume: 3, Issue:6

    Topics: Amino Acid Sequence; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Protein Conformation; Substance P

1986
Major metabolites of substance P degraded by spinal synaptic membranes antagonize the behavioral response to substance P in rats.
    Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:11

    Topics: Animals; Behavior, Animal; Drug Combinations; Injections, Spinal; Male; Peptide Fragments; Rats; Rats, Wistar; Spinal Cord; Substance P; Synaptic Membranes

1999
Neuropeptides and capsaicin stimulate the release of inflammatory cytokines in a human bronchial epithelial cell line.
    Neuropeptides, 1999, Volume: 33, Issue:6

    Topics: Bronchi; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cell Line, Transformed; Cytokines; Epithelial Cells; Gene Expression; Humans; Interleukin-6; Interleukin-8; Peptide Fragments; Piperidines; Protease Inhibitors; RNA, Messenger; Substance P; Thiorphan; Tumor Necrosis Factor-alpha

1999
Inhibitory effect of the substance P and its derivative on erythropoietin-independent growth of erythroid progenitors in polycythemia vera.
    Leukemia research, 2008, Volume: 32, Issue:5

    Topics: Cell Differentiation; Cell Proliferation; Cell Survival; Erythroid Precursor Cells; Erythropoietin; GTP-Binding Proteins; Humans; Peptide Fragments; Polycythemia Vera; Receptors, Tachykinin; RNA, Messenger; Substance P

2008