Compounds > suberoyl bis-hydroxamic acid
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suberoyl bis-hydroxamic acid and trichostatin a

suberoyl bis-hydroxamic acid has been researched along with trichostatin a in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (46.15)29.6817
2010's7 (53.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brosch, G; Gerhäuser, C; Jung, M; Loidl, P; Scherf, H; Wittich, S; Xie, C1
Burnett, R; Gottesfeld, JM; Herman, D; Jenssen, K; Perlman, SL; Soragni, E1
Andrews, KT; Boyle, GM; Fairlie, DP; Gardiner, DL; Kahnberg, P; Le, GT; Lucke, AJ; Skinner-Adams, TS; Tran, TN1
Avery, MA; Mukherjee, P; Pradhan, A; Shah, F; Tekwani, BL1
Bradner, JE; Grachan, ML; Greenberg, EF; Haggarty, SJ; Mazitschek, R; Warnow, T; West, N1
Bertrand, P; Blanquart, C; Bouchet, S; Cuendet, M; Lehotzky, A; Martinet, N; Nurisso, A; Ovadi, J; Simões-Pires, C; Zwick, V1
Bertrand, P; Cuendet, M; Dos Santos Passos, C; Martinet, N; Nurisso, A; Petit, C; Randazzo, GM; Simões-Pires, CA; Zwick, V1
Forgione, M; Hailu, GS; Mai, A; Robaa, D; Rotili, D; Sippl, W1
Cassell, M; Lindsay, DS; Mitchell, SM; Reilly, CM; Strobl, JS1
Europe-Finner, GN; Hehir, MP; Morrison, JJ; Moynihan, AT; Robson, SC; Sharkey, AM1
Burakowski, T; de Jager, W; Eldering, E; Grabiec, AM; Groot, D; Krausz, S; Maslinski, W; Prakken, BJ; Reedquist, KA; Sanders, ME; Tak, PP1
Boddeke, HW; Brouwer, N; Eggen, BJ; Hanisch, UK; Kannan, V; Regen, T1
Chikamatsu, K; Ishii, H; Masuyama, K; Murata, T; Sakakura, K; Shino, M; Takahashi, K; Toyoda, M1

Reviews

1 review(s) available for suberoyl bis-hydroxamic acid and trichostatin a

ArticleYear
Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives.
    Journal of medicinal chemistry, 2017, 06-22, Volume: 60, Issue:12

    Topics: Animals; Antiparasitic Agents; Drug Repositioning; Helminth Proteins; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Leishmania; Plasmodium; Protozoan Proteins; Schistosoma; Toxoplasma; Trypanosoma

2017

Other Studies

12 other study(ies) available for suberoyl bis-hydroxamic acid and trichostatin a

ArticleYear
Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells.
    Journal of medicinal chemistry, 2002, Jul-18, Volume: 45, Issue:15

    Topics: Acetylation; Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Enzyme Inhibitors; Friend murine leukemia virus; Histone Deacetylase Inhibitors; Histones; Leukemia, Experimental; Liver; Mice; Phenylalanine; Rats; Structure-Activity Relationship; Tumor Cells, Cultured; Zea mays

2002
Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia.
    Nature chemical biology, 2006, Volume: 2, Issue:10

    Topics: Acetylation; Alleles; Anilides; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Frataxin; Friedreich Ataxia; Gene Expression Regulation; Gene Silencing; HeLa Cells; Heterochromatin; Histone Deacetylase Inhibitors; Histones; Humans; Iron-Binding Proteins; Molecular Structure; RNA, Messenger; Transcription, Genetic

2006
Potent antimalarial activity of histone deacetylase inhibitor analogues.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Amino Acids, Dicarboxylic; Animals; Antimalarials; Cysteine; Drug Resistance; Enzyme Inhibitors; Erythrocytes; Histone Deacetylase Inhibitors; Humans; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Sequence Homology, Amino Acid

2008
Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy.
    Bioorganic & medicinal chemistry, 2008, May-01, Volume: 16, Issue:9

    Topics: Algorithms; Animals; Antimalarials; Binding Sites; Computer Simulation; Crystallography, X-Ray; Enzyme Inhibitors; Histone Deacetylases; Humans; Ligands; Models, Chemical; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Predictive Value of Tests; Structure-Activity Relationship

2008
Chemical phylogenetics of histone deacetylases.
    Nature chemical biology, 2010, Volume: 6, Issue:3

    Topics:

2010
Cross metathesis with hydroxamate and benzamide BOC-protected alkenes to access HDAC inhibitors and their biological evaluation highlighted intrinsic activity of BOC-protected dihydroxamates.
    Bioorganic & medicinal chemistry letters, 2016, Jan-01, Volume: 26, Issue:1

    Topics: Alkenes; Benzamides; Dose-Response Relationship, Drug; Formic Acid Esters; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2016
Synthesis of a selective HDAC6 inhibitor active in neuroblasts.
    Bioorganic & medicinal chemistry letters, 2016, 10-15, Volume: 26, Issue:20

    Topics: Blood-Brain Barrier; Cell Line, Tumor; Chromatography, High Pressure Liquid; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Neurons

2016
Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro.
    The Journal of parasitology, 2007, Volume: 93, Issue:3

    Topics: Animals; Antiprotozoal Agents; Butyrates; Cattle; Cell Line; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxylamines; Inhibitory Concentration 50; Niacinamide; Parasitic Sensitivity Tests; Phenylbutyrates; Quinolines; Toxoplasma; Valproic Acid; Vitamin B Complex; Vorinostat

2007
Histone deacetylase inhibitors and a functional potent inhibitory effect on human uterine contractility.
    American journal of obstetrics and gynecology, 2008, Volume: 199, Issue:2

    Topics: Adult; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; In Vitro Techniques; Oxytocics; Oxytocin; Pregnancy; Protein Synthesis Inhibitors; Uterine Contraction; Valproic Acid

2008
Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue.
    Journal of immunology (Baltimore, Md. : 1950), 2010, Mar-01, Volume: 184, Issue:5

    Topics: Adult; Aged; Apoptosis; Arthritis, Rheumatoid; Blotting, Western; Cells, Cultured; Female; Flow Cytometry; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Inflammation; Interleukin-6; Macrophages; Male; Middle Aged; Minor Histocompatibility Antigens; Niacinamide; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Synovial Membrane; Tumor Necrosis Factor-alpha

2010
Histone deacetylase inhibitors suppress immune activation in primary mouse microglia.
    Journal of neuroscience research, 2013, Volume: 91, Issue:9

    Topics: Animals; Antigens, Surface; Astrocytes; Brain; Cells, Cultured; Chemotactic Factors; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Interferon-gamma; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microglia; RNA, Messenger; Sirtuin 1; Sirtuin 2; Time Factors

2013
Alteration of cancer stem cell-like phenotype by histone deacetylase inhibitors in squamous cell carcinoma of the head and neck.
    Cancer science, 2013, Volume: 104, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Epithelial-Mesenchymal Transition; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Humans; Hyaluronan Receptors; Hydroxamic Acids; Neoplasm Proteins; Neoplastic Stem Cells; Phenotype; Squamous Cell Carcinoma of Head and Neck

2013