su-11248 and tetrandrine

su-11248 has been researched along with tetrandrine* in 1 studies

Other Studies

1 other study(ies) available for su-11248 and tetrandrine

ArticleYear
Design, synthesis and biological activities of tetrandrine and fangchinoline derivatives as antitumer agents.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    The isolation and modification of natural products is always a very important resources to anti-tumor drugs. Therefore, a novel series of tetrandrine and fangchinoline derivatives were designed and synthesized, and their antiproliferative activities against HepG2, MCF-7 cells were evaluated and described. From the activity result obtained, high to very high activity in vitro has been found, one of the tested compounds (compound 5d) exhibited the most significant cytotoxic effects. Compound 5d increased 29.2, 7.37 times anti-proliferative activity for HepG2 cells and MCF-7 cells compared to sunitinib (IC

    Topics: Antineoplastic Agents; Apoptosis; Benzylisoquinolines; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship

2017