Page last updated: 2024-08-18

styrene oxide and styrene

styrene oxide has been researched along with styrene in 125 studies

Research

Studies (125)

Timeframe	Studies, this research(%)	All Research%
pre-1990	27 (21.60)	18.7374
1990's	39 (31.20)	18.2507
2000's	39 (31.20)	29.6817
2010's	17 (13.60)	24.3611
2020's	3 (2.40)	2.80

Authors

Authors	Studies
Barale, R	1
Doane-Setzer, P; Rappaport, SM; Smith, MT; Ting, D; Woodlee, J	1
Filser, JG; Jiang, XL; Kessler, W	1
Bodell, WJ; Burlingame, AL; Kaur, S; Liu, SF; Pongracz, K; Rappaport, SM	1
Djurhuus, R; Lillehaug, JR; Male, R; Pryme, IF	1
Higashi, K; Inoue, N; Katoh, T	1
Fujishiro, K; Inoue, N; Mori, K	1
Ciliberti, A; Conti, B; Maltoni, C; Perino, G	1
Gill, SS; Grayson, MH	1
Catalano, CE; Choe, YS; DePillis, G; Ortiz de Montellano, PR	1
Fujita, H; Hayashi, N; Ikeda, M; Koizumi, A	1
Fujita, H; Furusawa, T; Ikeda, M; Koizumi, A	1
Bend, JR; Harris, C; Hernandez, O; Philpot, RM	1
Husain, R; Seth, PK; Srivastava, SP; Zaidi, NF	1
Byfält Nordqvist, M; Löf, A; Osterman-Golkar, S; Walles, SA	1
Belvedere, G; Tursi, F	2
Pohlová, H; Rössner, P; Srám, RJ	1
Gullstrand, E; Löf, A; Lundgren, E; Nordqvist, MB	1
Belvedere, G; Elovaara, E; Vainio, H	1
Belvedere, G; Hietanen, E; Talve, L; Vainio, H	1
Fregert, S; Sjöborg, S; Trulsson, L	1
Huff, JE	1
Norppa, H; Sorsa, M; Vainio, H	1
Bianchi, M; Lascialfari, D; Loprieno, N; Pantarotto, C; Rossi, AM; Sbrana, I; Tortoreto, M	1
Belvedere, G; Blezza, D; Cantoni, L	1
Beije, B; Jenssen, D	1
Ozawa, N; Watabe, T; Yoshikawa, K	2
Mackenzie, P; Vainio, H	1
Delbressine, LP; Seutter-Berlage, F; Smeets, FL; Van Bladeren, PJ	1
Preston, RJ; Scott, D	1
Buckley, CM; Dobson, AD; Hartmans, S; O'Connor, K	1
Christakopoulos, A; Osterman-Golkar, S; Svensson, K; Zorcec, V	1
Kirsch-Volders, M; Pauwels, W; Roosels, D; Severi, M; Van Hummelen, P; Veulemans, H	1
Filser, JG; Gfrörer, W; Kessler, W; Korn, M	1
Roe, FJ	1
Farmer, PB; Phillips, DH	1
McConnell, EE; Swenberg, JA	2
Durham, H; Kohn, J; Minotti, S	1
Leak, DJ; Matthews, CS; Rigby, SR	1
Csanády, GA; Filser, JG; Mendrala, AL; Nolan, RJ	1
Bodell, WJ; Horvath, E; Pongracz, K; Rappaport, S	1
Costa, LG; Faustman, EM; Gregotti, CF; Kirby, Z; Manzo, L	1
Chakrabarti, S; Duhr, MA; Richer, CL; Senécal-Quevillon, M	1
Langvardt, PW; Mendrala, AL; Nitschke, KD; Nolan, RJ; Quast, JF	1
Lee, SH; Norppa, H	1
Carlson, GP; DeNicola, DB; Gadberry, MG	1
Jin, Z; Rappaport, SM; Yeowell-O'Connell, K	1
Dobson, AD; Duetz, W; O'Connor, K; Wind, B	1
Bodell, W; Rappaport, SM; Symanski, E; Yager, JW; Yeowell-O'Connell, K	1
Capodaglio, E; Cavalleri, A; Ghittori, S; Gobba, F; Imbriani, M; Maestri, L	1
Bond, JA; Farris, GM; James, RA; Leavens, TL; Marshall, MW; Shah, R; Wong, VA	1
Carlson, GP	6
Jin, Z; Pauwels, W; Rappaport, SM; Severi, M; Veulemans, H; Walker, MR; Yeowell-O'Connell, K	1
Bailey, E; Cordero, R; Farmer, PB; Osterman-Golkar, S; Pauwels, W; Severi, M; Veulemans, H	1
Colombi, A; Colosio, C; Fustinoni, S; Lastrucci, L; Rappaport, SM; Yeowell-O'Connell, K	1
Linhart, I; Mládková, I; Smejkal, J	1
Panke, S; Schmid, A; Witholt, B; Wubbolts, MG	1
Hellman, B; Vaghef, H	1
Chakrabarti, SK	1
Kupper, LL; Nylander-French, LA; Rappaport, SM	1
Bluhm, S; Harris, CM; Harris, TM; Painter, SL; Stone, MP; Tamura, PJ; Zegar, IS	1
Rappaport, SM; Yeowell-O'Connell, K	1
Carlson, GP; DeNicola, DB; Hynes, DE	1
Gut, I; Linhart, I; Novák, J; Smejkal, J	1
Carlson, GP; Mantick, NA; Powley, MW	1
Ernstgård, L; Gullstrand, E; Johanson, G; Löf, A; Osterman-Golkar, S; Sumner, SC; Williams, CC	1
Andreoli, R; Bergamaschi, E; De Palma, G; Manini, P; Mutti, A; Niessen, WM	1
Lau, PC; Nishio, T; Patel, A; Wang, Y	1
Echeverria, D; Osterman-Golkar, S; Pérez, HL; Rappaport, SM; Tornero-Velez, R; Waidyanatha, S	1
Foster, J; Green, T; Lee, R; Lund, V; Meadowcroft, S; Toghill, A	1
Bárta, I; Hemminki, K; Koskinen, M; Smerák, P; Stetina, R; Vodicka, P; Vodicková, L	1
Andreoli, R; Bergamaschi, E; Cavazzini, S; De Palma, G; Franchini, I; Manini, P; Mozzoni, P; Mutti, A	1
Rappaport, SM; Tornero-Velez, R	2
Csanády, GA; Filser, JG; Kessler, W	1
Lutz, U; Lutz, WK; Otteneder, M	1
Arand, M; Hemminki, K; Koskinen, M; Oesch, F; Vodicka, P	1
Andersen, ME; Clewell, HJ; Cruzan, G; Sarangapani, R; Teeguarden, JG	1
Held, M; Panke, S; Schmid, A; Witholt, B; Wubbolts, MG	1
Estavillo, C; Rusling, JF; Schenkman, JB; Stuart, JD; Yang, J; Zhou, L	1
Csanády, GA; Filser, JG; Hoffmann, HD; Kessler, W	1
Carlson, G	1
Hofstetter, K; Otto, K; Röthlisberger, M; Schmid, A; Witholt, B	1
Carlson, GP; Mantick, NA; Turner, M	2
de Visser, SP; Kumar, D; Shaik, S	1
Kaufmann, W; Landsiedel, R; Mellert, W; Poole, A; van Ravenzwaay, B	1
Csanády, GA; Faller, TH; Filser, JG; Hofmann, C; Pütz, C; Semder, B	1
Arany, S; Hirasawa, F; Kawagoe, M; Koizumi, Y; Sugiyama, T; Ueno, Y	1
Echeverria, D; Kupper, LL; Nylander-French, LA; Rappaport, SM; Serdar, B; Tornero-Velez, R	1
Bühler, B; Habicher, T; Hauer, B; Panke, S; Park, JB; Schmid, A; Witholt, B	1
Chung, JK; Liu, G; Yuan, W; Zheng, J	1
Carlson, GP; Harvilchuck, JA	2
Costa, C; Farmer, PB; Gaspar, J; Mayan, O; Roach, J; Roma-Torres, J; Rueff, J; Silva, S; Teixeira, JP	1
Farmer, PB; Gaspar, J; Mayan, O; Roach, J; Rueff, J; Silva, S; Teixeira, JP; Torres, J	1
Gross, R; Hauer, B; Otto, K; Schmid, A	1
Buratti, M; Campo, L; Colombi, A; De Palma, G; Foa, V; Fustinoni, S; Manini, P; Mutti, A; Rappaport, SM; Waidyanatha, S	1
Alexandrova, E; Anderson, D; Cemeli, E; Chiuchiarelli, G; Mirkova, E	1
Eulberg, D; Kaschabek, SR; Lakner, S; Schlömann, M; Tischler, D; van Berkel, WJ	1
Carlson, GP; Harvilchuck, JA; Klaunig, JE; Pu, X	1
Chung, JK; Jin, H; Yuan, W; Zheng, J	1
Bennett, B; Fung, LW; Horner, JH; Newcomb, M; Sheng, X; Yuan, X	1
Banton, M; Bus, J; Cruzan, G; Harkema, J; Hotchkiss, J; Sarang, S	1
Cosnier, F; Cossec, B; Gaté, L; Nunge, H	1
Binet, S; Cosnier, F; Darne, C; Gaté, L; Guichard, Y; Langlais, C; Micillino, JC; Nunge, H; Sébillaud, S	1
Bühler, B; Kuhn, D; Schmid, A	1
Banton, M; Bus, J; Cruzan, G; Hotchkiss, J; Moore, C; Sarang, S; Sura, R; Yost, G	1
Ding, X; Li, L; Shen, S; Zheng, J	1
Buehler, K; Halan, B; Karande, R; Schmid, A	1
Bühler, B; Neumann, C; Schmid, A; Volmer, J	1
Filser, JG; Gelbke, HP	1
Bin, P; Dai, Y; Ji, Y; Meng, T; Miao, P; Niu, Y; Zheng, Y	1
Williamson, J	1
Doukyu, N; Iida, S	1
Huang, H; Lv, J; Meng, XG; Wang, F; Wu, YY; Yu, WW	1
Delgado, E; Pecchi, G; Saavedra-Torres, M; Schott, E; Toledo, F; Zarate, X	1

Reviews

7 review(s) available for styrene oxide and styrene

Article	Year
The genetic toxicology of styrene and styrene oxide. Mutation research, 1991, Volume: 257, Issue:2 Topics: Animals; Epoxy Compounds; Humans; Mutagens; Plants; Styrene; Styrenes	1991
A re-evaluation of the cytogenetic effects of styrene. Mutation research, 1994, Volume: 318, Issue:3 Topics: Animals; Chromosome Aberrations; Dose-Response Relationship, Drug; Epoxy Compounds; Humans; Micronuclei, Chromosome-Defective; Sister Chromatid Exchange; Styrene; Styrenes	1994
Styrene: toxicity studies--what do they show? Critical reviews in toxicology, 1994, Volume: 24 Suppl Topics: Animals; Carcinogenicity Tests; Carcinogens; Environmental Pollution; Epoxy Compounds; Humans; Mutagenicity Tests; Mutagens; Occupational Exposure; Reproduction; Styrene; Styrenes	1994
Evidence for DNA and protein binding by styrene and styrene oxide. Critical reviews in toxicology, 1994, Volume: 24 Suppl Topics: Animals; DNA Adducts; Epoxy Compounds; Hemoglobins; Humans; Mutagens; Neoplasms; Occupational Exposure; Protein Binding; Styrene; Styrenes	1994
Review of styrene and styrene oxide long-term animal studies. Critical reviews in toxicology, 1994, Volume: 24 Suppl Topics: Animals; Carcinogenicity Tests; Carcinogens; Epoxy Compounds; Styrene; Styrenes; Time Factors	1994
Styrene and styrene oxide: results of studies on carcinogenicity in experimental animals. IARC scientific publications, 1993, Issue:127 Topics: Animals; Carcinogens; Epoxy Compounds; Female; Male; Neoplasms, Experimental; Styrene; Styrenes	1993
Spectrum of styrene-induced DNA adducts: the relationship to other biomarkers and prospects in human biomonitoring. Mutation research, 2002, Volume: 511, Issue:3 Topics: Animals; Binding Sites; Biomarkers; DNA; DNA Adducts; Environmental Monitoring; Epoxy Compounds; Humans; In Vitro Techniques; Mutagens; Occupational Exposure; Risk Assessment; Styrene	2002

Trials

2 trial(s) available for styrene oxide and styrene

Article	Year
Styrene-7,8-oxide in blood of workers exposed to styrene. Archives of toxicology, 1994, Volume: 68, Issue:8 Topics: Adult; Chromatography, Gas; Epoxy Compounds; Germany; Humans; Linear Models; Male; Middle Aged; Occupational Exposure; Styrene; Styrenes	1994
Albumin and hemoglobin adducts as biomarkers of exposure to styrene in fiberglass-reinforced-plastics workers. International archives of occupational and environmental health, 1998, Volume: 71, Issue:1 Topics: Adult; Albumins; Analysis of Variance; Biomarkers; Carcinogens; Chemical Industry; Chromatography, High Pressure Liquid; Environmental Monitoring; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Glass; Glyoxylates; Hemoglobins; Humans; Linear Models; Male; Mandelic Acids; Occupational Exposure; Plastics; Sensitivity and Specificity; Styrene; Styrenes	1998

Article

Year

Styrene-7,8-oxide in blood of workers exposed to styrene.

Archives of toxicology, 1994, Volume: 68, Issue:8

Topics: Adult; Chromatography, Gas; Epoxy Compounds; Germany; Humans; Linear Models; Male; Middle Aged; Occupational Exposure; Styrene; Styrenes

1994

Albumin and hemoglobin adducts as biomarkers of exposure to styrene in fiberglass-reinforced-plastics workers.

International archives of occupational and environmental health, 1998, Volume: 71, Issue:1

Topics: Adult; Albumins; Analysis of Variance; Biomarkers; Carcinogens; Chemical Industry; Chromatography, High Pressure Liquid; Environmental Monitoring; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Glass; Glyoxylates; Hemoglobins; Humans; Linear Models; Male; Mandelic Acids; Occupational Exposure; Plastics; Sensitivity and Specificity; Styrene; Styrenes

1998

Other Studies

116 other study(ies) available for styrene oxide and styrene

Article	Year
Measurement of styrene-oxide cysteine adducts in hemoglobin by selective catalytic reduction. Advances in experimental medicine and biology, 1991, Volume: 283 Topics: Alkylation; Animals; Cysteine; Epoxy Compounds; Erythrocytes; Globins; Hemoglobins; Humans; In Vitro Techniques; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains; Styrene; Styrenes	1991
Direct determination of styrene-7,8-oxide in blood by gas chromatography with flame ionization detection. Journal of chromatography, 1990, Dec-14, Volume: 534 Topics: Animals; Atmosphere Exposure Chambers; Epoxy Compounds; Flame Ionization; Male; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Styrene; Styrenes	1990
Investigation of styrene oxide-DNA adducts and their detection in workers exposed to styrene. Progress in clinical and biological research, 1990, Volume: 340C Topics: DNA; Environmental Exposure; Epoxy Compounds; Ethers, Cyclic; Humans; Lymphocytes; Occupations; Styrene; Styrenes	1990
In vitro transformation and tumor promotion studies of styrene and styrene oxide. Carcinogenesis, 1985, Volume: 6, Issue:9 Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Choline; Cocarcinogenesis; DNA; Endoplasmic Reticulum; Epoxy Compounds; Ethers, Cyclic; Fibroblasts; Methylcholanthrene; Mice; Neoplasms, Experimental; RNA; Styrene; Styrenes	1985
Sub-chronic effects of styrene and styrene oxide on lipid peroxidation and the metabolism of glutathione in rat liver and brain. The Journal of toxicological sciences, 1989, Volume: 14, Issue:1 Topics: Animals; Brain; Epoxy Compounds; Ethers, Cyclic; Glutathione; Glutathione Disulfide; Glutathione Reductase; Lipid Peroxidation; Lipid Peroxides; Liver; Male; Rats; Rats, Inbred Strains; Styrene; Styrenes	1989
[Inhibition of delta-aminolevulinic acid dehydratase by styrene and styrene oxide]. Journal of UOEH, 1988, Sep-01, Volume: 10, Issue:3 Topics: Animals; Epoxy Compounds; Erythrocytes; Ethers, Cyclic; Liver; Male; Porphobilinogen Synthase; Rats; Rats, Inbred Strains; Styrene; Styrenes	1988
Long-term carcinogenicity bioassays on styrene administered by inhalation, ingestion and injection and styrene oxide administered by ingestion in Sprague-Dawley rats, and para-methylstyrene administered by ingestion in Sprague-Dawley rats and Swiss mice. Annals of the New York Academy of Sciences, 1988, Volume: 534 Topics: Administration, Inhalation; Administration, Oral; Animals; Biological Assay; Epoxy Compounds; Ethers, Cyclic; Injections, Intravenous; Mammary Neoplasms, Experimental; Mice; Rats; Rats, Inbred Strains; Stomach Neoplasms; Styrene; Styrenes	1988
Effect of in vitro exposure to styrene, styrene oxide, and other structurally related compounds on murine cell-mediated immunity. Immunopharmacology, 1986, Volume: 11, Issue:3 Topics: Animals; Cell Line; Cytotoxicity, Immunologic; DNA Replication; Epoxy Compounds; Ethers, Cyclic; Female; Immunity, Cellular; Kinetics; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Spleen; Structure-Activity Relationship; Styrene; Styrenes; T-Lymphocytes, Cytotoxic	1986
Structure-mechanism relationships in hemoproteins. Oxygenations catalyzed by chloroperoxidase and horseradish peroxidase. The Journal of biological chemistry, 1987, Aug-25, Volume: 262, Issue:24 Topics: Acetaldehyde; Animals; Chemical Phenomena; Chemistry; Chloride Peroxidase; Cytochrome P-450 Enzyme System; Epoxy Compounds; Hemeproteins; Horseradish Peroxidase; Magnetic Resonance Spectroscopy; Microsomes, Liver; Oxygen; Peroxidases; Rats; Structure-Activity Relationship; Styrene; Styrenes	1987
Reduced synthesis of 5-aminolevulinate dehydratase in styrene-treated rats. Biochimica et biophysica acta, 1986, Jun-20, Volume: 867, Issue:3 Topics: Animals; Cell-Free System; Depression, Chemical; Epoxy Compounds; Erythrocytes; Liver; Male; Porphobilinogen Synthase; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains; RNA, Messenger; Styrene; Styrenes; Transcription, Genetic	1986
Decreased erythrocyte delta-aminolevulinate dehydratase activity after styrene exposure. Biochemical pharmacology, 1987, Mar-01, Volume: 36, Issue:5 Topics: Animals; Bone Marrow; Environmental Exposure; Epoxy Compounds; Erythrocytes; Glutathione; Humans; Male; Porphobilinogen Synthase; Rats; Rats, Inbred Strains; Styrene; Styrenes	1987
Rabbit pulmonary cytochrome P-450 monooxygenase system: isozyme differences in the rate and stereoselectivity of styrene oxidation. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1 Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Epoxy Compounds; Glutathione; In Vitro Techniques; Isoenzymes; Lung; Male; Microsomes; Oxidation-Reduction; Oxygenases; Rabbits; Stereoisomerism; Styrene; Styrenes	1986
Effect of styrene oxide on levels of biogenic amines and activity of monoamine oxidase in different parts of rat brain. Bulletin of environmental contamination and toxicology, 1985, Volume: 34, Issue:5 Topics: Animals; Biogenic Amines; Brain Chemistry; Epoxy Compounds; Ethers, Cyclic; Male; Monoamine Oxidase; Rats; Styrene; Styrenes	1985
Covalent binding of styrene and styrene-7,8-oxide to plasma proteins, hemoglobin and DNA in the mouse. Chemico-biological interactions, 1985, Volume: 55, Issue:1-2 Topics: Alkylating Agents; Alkylation; Animals; Blood Proteins; DNA; Dose-Response Relationship, Drug; Epoxy Compounds; Ethers, Cyclic; Hemoglobins; Liver; Male; Mice; Styrene; Styrenes	1985
Styrene oxidation to styrene oxide by hydroxyl radicals produced during reaction of xanthine with xanthine oxidase in the presence of Fe3+. Toxicology letters, 1983, Volume: 16, Issue:1-2 Topics: Chemical Phenomena; Chemistry; Epoxy Compounds; Ethers, Cyclic; Ferric Compounds; Free Radicals; Hydroxides; Hydroxyl Radical; Oxidation-Reduction; Styrene; Styrenes; Xanthine; Xanthine Oxidase; Xanthines	1983
Cytogenetic analysis of human peripheral blood lymphocytes in culture exposed in vitro to styrene and styrene oxide. Journal of hygiene, epidemiology, microbiology, and immunology, 1984, Volume: 29, Issue:3 Topics: Adult; Cells, Cultured; Chromosome Aberrations; Dose-Response Relationship, Drug; Epoxy Compounds; Ethers, Cyclic; Female; Humans; Lymphocytes; Sister Chromatid Exchange; Styrene; Styrenes; Thiotepa	1984
Occurrence of styrene-7,8-oxide and styrene glycol in mouse after the administration of styrene. Scandinavian journal of work, environment & health, 1984, Volume: 10, Issue:3 Topics: Animals; Epoxy Compounds; Ethers, Cyclic; Ethylene Glycols; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Styrene; Styrenes; Tissue Distribution	1984
Activation of styrene to styrene oxide in hepatocytes and subcellular fractions of rat liver. Toxicology letters, 1984, Volume: 23, Issue:2 Topics: Animals; Cell Survival; Epoxy Compounds; Ethers, Cyclic; Ethylene Glycols; Glutathione; Liver; Male; NADP; Rats; Rats, Inbred Strains; Styrene; Styrenes; Subcellular Fractions; Time Factors	1984
Effect of blood on styrene oxidation in perfused rat liver. Toxicology letters, 1984, Volume: 23, Issue:3 Topics: Animals; Biotransformation; Epoxy Compounds; Erythrocytes; Ethylene Glycols; Liver; Oxidation-Reduction; Oxyhemoglobins; Perfusion; Rats; Styrene; Styrenes	1984
Contact allergy to styrene and related chemicals. Contact dermatitis, 1984, Volume: 10, Issue:2 Topics: Dermatitis, Atopic; Dermatitis, Contact; Epoxy Compounds; Food Hypersensitivity; Haptens; Humans; Patch Tests; Phenols; Styrene; Styrenes	1984
Styrene, styrene oxide, polystyrene, and beta-nitrostyrene/styrene carcinogenicity in rodents. Progress in clinical and biological research, 1984, Volume: 141 Topics: Animals; Carcinogens; Chemical Industry; Epoxy Compounds; Ethers, Cyclic; Female; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Polystyrenes; Rats; Stomach Neoplasms; Styrene; Styrenes	1984
Metabolic activation of styrene by erythrocytes detected as increased sister chromatid exchanges in cultured human lymphocytes. Cancer research, 1983, Volume: 43, Issue:8 Topics: Biotransformation; Crossing Over, Genetic; Cyclophosphamide; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Humans; Leukocyte Count; Lymphocytes; Sister Chromatid Exchange; Styrene; Styrenes	1983
Bone marrow cell chromosomal aberrations and styrene biotransformation in mice given styrene on a repeated oral schedule. Chemico-biological interactions, 1983, Aug-01, Volume: 45, Issue:3 Topics: Administration, Oral; Animals; Biotransformation; Bone Marrow; Chromosome Aberrations; Epoxy Compounds; Kinetics; Male; Mice; Styrene; Styrenes	1983
Ferrodoxin reductase catalyzes styrene oxidation to styrene oxide. Experientia, 1982, Mar-15, Volume: 38, Issue:3 Topics: Epoxy Compounds; Ferredoxin-NADP Reductase; Kinetics; NADH, NADPH Oxidoreductases; Styrene; Styrenes; Superoxide Dismutase; Xanthine Oxidase	1982
Investigation of styrene in the liver perfusion/cell culture system. No indication of styrene-7,8-oxide as the principal mutagenic metabolite produced by the intact rat liver. Chemico-biological interactions, 1982, Mar-01, Volume: 39, Issue:1 Topics: Animals; Blood Proteins; Cells, Cultured; Cricetinae; Cricetulus; Epoxy Compounds; Ethers, Cyclic; In Vitro Techniques; Lactates; Lactic Acid; Liver; Liver Function Tests; Male; Microsomes, Liver; Mutagens; Rats; Rats, Inbred Strains; Styrene; Styrenes; Subcellular Fractions; Thioguanine	1982
Studies on metabolism and toxicity of styrene. V. The metabolism of styrene, racemic, (R)-(+)-, and (S)-(--)-phenyloxiranes in the rat. Journal of pharmacobio-dynamics, 1982, Volume: 5, Issue:2 Topics: Acetylcysteine; Animals; Epoxy Compounds; Ethers, Cyclic; Hydrolysis; Rats; Rats, Inbred Strains; Stereoisomerism; Styrene; Styrenes	1982
Stereochemistry in the oxidative metabolism of styrene by hepatic microsomes. Biochemical pharmacology, 1981, Jun-15, Volume: 30, Issue:12 Topics: Animals; Epoxy Compounds; Ethylene Glycols; In Vitro Techniques; Microsomes, Liver; Rats; Stereoisomerism; Styrene; Styrenes	1981
Styrene oxidation to styrene oxide in human blood erythrocytes and lymphocytes. Research communications in chemical pathology and pharmacology, 1981, Volume: 33, Issue:2 Topics: Epoxy Compounds; Erythrocytes; Ethers, Cyclic; Humans; In Vitro Techniques; Kinetics; Lymphocytes; Oxidation-Reduction; Oxyhemoglobins; Styrene; Styrenes	1981
Interactions of styrene and styrene oxide with partially purified cytochrome P-450 and P-448 from rat liver microsomes. Toxicology letters, 1981, Volume: 9, Issue:2 Topics: Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Epoxy Compounds; Ethers, Cyclic; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Phosphatidylcholines; Protein Binding; Rats; Rats, Inbred Strains; Styrene; Styrenes	1981
Stereoselective oxidation of styrene to styrene oxide in rats as measured by mercapturic acid excretion. Xenobiotica; the fate of foreign compounds in biological systems, 1981, Volume: 11, Issue:9 Topics: Acetylcysteine; Animals; Epoxy Compounds; Ethers, Cyclic; Female; Glutathione Transferase; Magnetic Resonance Spectroscopy; Rats; Rats, Inbred Strains; Stereoisomerism; Styrene; Styrenes	1981
Possible regulatory role for nonaromatic carbon sources in styrene degradation by Pseudomonas putida CA-3. Applied and environmental microbiology, 1995, Volume: 61, Issue:2 Topics: Aldehyde Oxidoreductases; Biodegradation, Environmental; Carbon; Citrates; Citric Acid; Environmental Pollutants; Epoxy Compounds; Escherichia coli Proteins; Glutamic Acid; Isomerases; Oxygen; Oxygenases; Phenylacetates; Pseudomonas putida; Styrene; Styrenes	1995
Dosimetry of styrene 7,8-oxide in styrene- and styrene oxide-exposed mice and rats by quantification of haemoglobin adducts. Chemico-biological interactions, 1995, Mar-30, Volume: 95, Issue:1-2 Topics: Animals; Blood Proteins; Dose-Response Relationship, Drug; Drug Stability; Epoxy Compounds; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Male; Mice; Mice, Inbred Strains; Protein Binding; Rats; Rats, Sprague-Dawley; Species Specificity; Styrene; Styrenes	1995
Urinary mandelic acid and hemoglobin adducts in fiberglass-reinforced plastics workers exposed to styrene. Scandinavian journal of work, environment & health, 1994, Volume: 20, Issue:6 Topics: Adult; Air Pollutants, Occupational; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Glass; Hemoglobins; Humans; Industry; Male; Mandelic Acids; Middle Aged; Occupational Exposure; Sensitivity and Specificity; Styrene; Styrenes	1994
Assessment of the neurotoxicity of styrene, styrene oxide, and styrene glycol in primary cultures of motor and sensory neurons. Toxicology letters, 1995, Volume: 75, Issue:1-3 Topics: Animals; Cells, Cultured; Epoxy Compounds; Ethylene Glycols; Ganglia, Spinal; Membrane Potentials; Mice; Motor Neurons; Neurons, Afferent; Styrene; Styrenes	1995
Expoxidation of styrene and substituted styrenes by whole cells of Mycobacterium sp. M156. Bioorganic & medicinal chemistry, 1994, Volume: 2, Issue:6 Topics: Biotransformation; Chromatography, Gas; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Kinetics; Mycobacterium; Optical Rotation; Stereoisomerism; Styrene; Styrenes; Substrate Specificity	1994
A physiologic pharmacokinetic model for styrene and styrene-7,8-oxide in mouse, rat and man. Archives of toxicology, 1994, Volume: 68, Issue:3 Topics: Administration, Inhalation; Administration, Oral; Animals; Epoxy Compounds; Glutathione; Humans; Hydrolysis; Injections, Intraperitoneal; Injections, Intravenous; Intestinal Absorption; Mice; Models, Biological; Pulmonary Alveoli; Rats; Solubility; Species Specificity; Styrene; Styrenes; Thermodynamics	1994
32P-post-labeling detection of DNA adducts in mononuclear cells of workers occupationally exposed to styrene. Carcinogenesis, 1994, Volume: 15, Issue:7 Topics: DNA; Epoxy Compounds; Female; Humans; Leukocytes, Mononuclear; Male; Occupational Exposure; Phosphorus Radioisotopes; Sister Chromatid Exchange; Styrene; Styrenes	1994
Effects of styrene oxide on differentiation and viability of rodent embryo cultures. Toxicology and applied pharmacology, 1994, Volume: 128, Issue:1 Topics: Animals; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Epoxy Compounds; Lethal Dose 50; Rats; Rats, Sprague-Dawley; Styrene; Styrenes	1994
Dose-dependent genotoxic effects of styrene on human blood lymphocytes and the relationship to its oxidative and metabolic effects. Environmental and molecular mutagenesis, 1993, Volume: 22, Issue:2 Topics: Biotransformation; Cell Cycle; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Epoxy Compounds; Ethylene Glycols; Glutathione; Humans; Lymphocytes; Mutagenicity Tests; Mutagens; Sister Chromatid Exchange; Styrene; Styrenes	1993
In vitro kinetics of styrene and styrene oxide metabolism in rat, mouse, and human. Archives of toxicology, 1993, Volume: 67, Issue:1 Topics: Administration, Inhalation; Animals; Epoxide Hydrolases; Epoxy Compounds; Glutathione Transferase; Humans; Indicators and Reagents; Liver; Lung; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Species Specificity; Styrene; Styrenes	1993
Effects of indomethacin and arachidonic acid on sister chromatid exchange induction by styrene and styrene-7,8-oxide. Mutation research, 1995, Volume: 348, Issue:4 Topics: Adult; Analysis of Variance; Antimutagenic Agents; Arachidonic Acid; Cells, Cultured; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Epoxy Compounds; Glutathione; Humans; Indomethacin; Lymphocytes; Male; Mutagens; Oxidation-Reduction; Sister Chromatid Exchange; Styrene; Styrenes	1995
Pneumotoxicity and hepatotoxicity of styrene and styrene oxide. Journal of toxicology and environmental health, 1996, Jun-28, Volume: 48, Issue:3 Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bronchoalveolar Lavage Fluid; Buthionine Sulfoximine; Carcinogens; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Epoxy Compounds; gamma-Glutamyltransferase; Injections, Intraperitoneal; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Liver; Liver Diseases; Lung Diseases; Male; Methionine Sulfoximine; Mice; Phenobarbital; Pyridines; Styrene; Styrenes; Trichloroepoxypropane	1996
Determination of albumin and hemoglobin adducts in workers exposed to styrene and styrene oxide. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1996, Volume: 5, Issue:3 Topics: Air Pollutants, Occupational; Benzyl Alcohols; Carboxylic Acids; Carcinogens; Cohort Studies; Cysteine; Diet; DNA Adducts; Environmental Pollutants; Epoxy Compounds; Ethylene Glycols; Female; Follow-Up Studies; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Hydrolysis; Male; Occupational Exposure; Phenylethyl Alcohol; Plastics; Serum Albumin; Ships; Styrene; Styrenes	1996
The effect of nutrient limitation on styrene metabolism in Pseudomonas putida CA-3. Applied and environmental microbiology, 1996, Volume: 62, Issue:10 Topics: Aldehyde Oxidoreductases; Biodegradation, Environmental; Epoxy Compounds; Escherichia coli Proteins; Glutamic Acid; Isomerases; Oxidation-Reduction; Oxygen Consumption; Phenylacetates; Pseudomonas putida; Styrene; Styrenes; Succinates; Succinic Acid	1996
An investigation of multiple biomarkers among workers exposed to styrene and styrene-7,8-oxide. Cancer research, 1996, Dec-01, Volume: 56, Issue:23 Topics: Adult; Air Pollutants, Occupational; Biomarkers; Biotransformation; Carcinogenicity Tests; Carcinogens, Environmental; Cohort Studies; DNA; DNA Adducts; Epoxy Compounds; Female; Humans; Industry; Linear Models; Male; Microsomes, Liver; Occupational Exposure; Serum Albumin; Sister Chromatid Exchange; Smoking; Styrene; Styrenes	1996
Excretion of N-acetyl-S-(1-phenyl-2-hydroxyethyl)-cysteine and N-acetyl-S-(2-phenyl-2-hydroxyethyl)-cysteine in workers exposed to styrene. The Science of the total environment, 1997, Jun-20, Volume: 199, Issue:1-2 Topics: Acetylcysteine; Animals; Binding Sites; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Cysteine; Environmental Monitoring; Epoxy Compounds; Glutathione; Glyoxylates; Humans; Male; Mandelic Acids; Mercaptoethanol; o-Phthalaldehyde; Occupational Exposure; Rats; Reference Standards; Spectrometry, Fluorescence; Stereoisomerism; Styrene; Styrenes; Ultrafiltration	1997
Genotoxicity and cytotoxicity in male B6C3F1 mice following exposure to mixtures of 1,3-butadiene and styrene. Environmental and molecular mutagenesis, 1997, Volume: 29, Issue:4 Topics: Animals; Bone Marrow; Butadienes; Carcinogens; Dose-Response Relationship, Drug; Drug Synergism; Epoxy Compounds; Erythrocytes; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mutagenicity Tests; Mutagens; Spleen; Styrene; Styrenes; Thymus Gland; Toxicity Tests	1997
Effects of inducers and inhibitors on the microsomal metabolism of styrene to styrene oxide in mice. Journal of toxicology and environmental health, 1997, Aug-08, Volume: 51, Issue:5 Topics: Animals; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Enzyme Induction; Enzyme Inhibitors; Epoxy Compounds; Injections, Intraperitoneal; Lung; Male; Mice; Microsomes; Microsomes, Liver; Phenobarbital; Pyridines; Species Specificity; Styrene; Styrenes	1997
Comparison of styrene-7,8-oxide adducts formed via reaction with cysteine, N-terminal valine and carboxylic acid residues in human, mouse and rat hemoglobin. Chemico-biological interactions, 1997, Aug-29, Volume: 106, Issue:1 Topics: Animals; Binding Sites; Biotransformation; Carboxylic Acids; Cysteine; Epoxy Compounds; Hemoglobins; Humans; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley; Species Specificity; Styrene; Styrenes; Substrate Specificity; Valine	1997
Ring test for the determination of N-terminal valine adducts of styrene 7,8-oxide with haemoglobin by the modified Edman degradation technique. Journal of chromatography. B, Biomedical sciences and applications, 1997, Nov-21, Volume: 702, Issue:1-2 Topics: Alkylation; Animals; Dose-Response Relationship, Drug; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Styrene; Styrenes; Valine	1997
Stereochemical aspects of styrene biotransformation. Toxicology letters, 1998, Jan-31, Volume: 94, Issue:2 Topics: Acetylcysteine; Animals; Biotransformation; Epoxy Compounds; Female; Magnetic Resonance Spectroscopy; Male; Mandelic Acids; Mutagens; Rats; Rats, Wistar; Stereoisomerism; Styrene; Styrenes	1998
Towards a biocatalyst for (S)-styrene oxide production: characterization of the styrene degradation pathway of Pseudomonas sp. strain VLB120. Applied and environmental microbiology, 1998, Volume: 64, Issue:6 Topics: Base Sequence; Biodegradation, Environmental; Biotechnology; Catalysis; Cloning, Molecular; DNA Primers; Epoxy Compounds; Escherichia coli; Genes, Bacterial; Genes, Regulator; Isomerases; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Oxygenases; Pseudomonas; Recombination, Genetic; RNA, Messenger; Sequence Deletion; Stereoisomerism; Styrene; Styrenes	1998
Detection of styrene and styrene oxide-induced DNA damage in various organs of mice using the comet assay. Pharmacology & toxicology, 1998, Volume: 83, Issue:2 Topics: Animals; Bone Marrow; Cyclophosphamide; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Epoxy Compounds; Female; Injections, Intraperitoneal; Kidney; Liver; Lymphocytes; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Mutagens; Styrene	1998
Styrene and styrene oxide affect the transport of dopamine in purified rat striatal synaptic vesicles. Biochemical and biophysical research communications, 1999, Feb-05, Volume: 255, Issue:1 Topics: Animals; Biological Transport; Dopamine; Epoxy Compounds; Humans; Mutagens; Rats; Styrene; Synapses; Synaptic Vesicles; Visual Cortex	1999
An investigation of factors contributing to styrene and styrene-7,8-oxide exposures in the reinforced-plastics industry. The Annals of occupational hygiene, 1999, Volume: 43, Issue:2 Topics: Carcinogens; Environmental Monitoring; Epoxy Compounds; Finland; Humans; Industry; Linear Models; Mutagens; Occupational Exposure; Occupations; Plastics; Resins, Plant; Risk Factors; Styrene	1999
Influence of the R(61,2)- and S(61,2)-alpha-(N6-adenyl)styrene oxide adducts on the A.C mismatched base pair in an oligodeoxynucleotide containing the human N-ras codon 61. Biochemistry, 1999, Jul-06, Volume: 38, Issue:27 Topics: Adenine; Base Pair Mismatch; Codon; Cytosine; DNA Adducts; Epoxy Compounds; Genes, ras; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Oligodeoxyribonucleotides; Protons; Stereoisomerism; Styrene; Thermodynamics	1999
Protein adducts as dosimeters of human exposure to styrene, styrene-7,8-oxide, and benzene. Toxicology letters, 1999, Sep-05, Volume: 108, Issue:2-3 Topics: Air Pollutants; Benzene; Biomarkers; Carcinogens; Cyclohexanes; Cysteine; Environmental Monitoring; Epoxy Compounds; Hemoglobins; Humans; Kinetics; Linear Models; Occupational Exposure; Protein Binding; Serum Albumin; Solvents; Styrene	1999
Metabolism of styrene by mouse and rat isolated lung cells. Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 51, Issue:2 Topics: Animals; Cell Separation; Cells, Cultured; Cytochrome P-450 Enzyme System; Epoxy Compounds; Isoenzymes; Lung; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Stereoisomerism; Styrene; Substrate Specificity	1999
Biotransformation of styrene in mice. Stereochemical aspects. Chemical research in toxicology, 2000, Volume: 13, Issue:1 Topics: Acetylcysteine; Animals; Biotransformation; Carbon Isotopes; Carcinogens; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Male; Mandelic Acids; Mice; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Styrene	2000
Metabolism of styrene by human liver and lung. Journal of toxicology and environmental health. Part A, 2000, Apr-28, Volume: 59, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Animals; Benzene; Carcinogens; Chromatography, High Pressure Liquid; Epoxy Compounds; Female; Humans; Lung; Male; Mice; Microsomes, Liver; Middle Aged; Phenol; Styrene	2000
Styrene oxide in blood, hemoglobin adducts, and urinary metabolites in human volunteers exposed to (13)C(8)-styrene vapors. Toxicology and applied pharmacology, 2000, Oct-01, Volume: 168, Issue:1 Topics: Carbon Isotopes; Chromatography, High Pressure Liquid; Epoxy Compounds; Glyoxylates; Hemoglobins; Hippurates; Humans; Magnetic Resonance Spectroscopy; Male; Mandelic Acids; Styrene; Volatilization	2000
A new method for the analysis of styrene mercapturic acids by liquid chromatography/electrospray tandem mass spectrometry. Rapid communications in mass spectrometry : RCM, 2000, Volume: 14, Issue:21 Topics: Acetylcysteine; Chromatography, Liquid; Environmental Pollutants; Epoxy Compounds; Glutathione; Glyoxylates; Humans; Mandelic Acids; Molecular Structure; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Styrene	2000
Biotransformations catalyzed by cloned p-cymene monooxygenase from Pseudomonas putida F1. Applied microbiology and biotechnology, 2001, Volume: 55, Issue:3 Topics: Bacterial Proteins; Benzyl Alcohol; Biotransformation; Cloning, Molecular; Epoxy Compounds; Escherichia coli; Gas Chromatography-Mass Spectrometry; Oxidoreductases; Pseudomonas putida; Styrene; Substrate Specificity; Toluene	2001
Determination of styrene and styrene-7,8-oxide in human blood by gas chromatography-mass spectrometry. Journal of chromatography. B, Biomedical sciences and applications, 2001, Jun-05, Volume: 757, Issue:1 Topics: Air; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Sensitivity and Specificity; Styrene	2001
The toxicity of styrene to the nasal epithelium of mice and rats: studies on the mode of action and relevance to humans. Chemico-biological interactions, 2001, Aug-31, Volume: 137, Issue:2 Topics: Alkynes; Animals; Benzene Derivatives; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Epoxide Hydrolases; Epoxy Compounds; Glutathione Transferase; Humans; Male; Mice; Microsomes; Mutagens; Nasal Mucosa; Rats; Rats, Sprague-Dawley; Styrene	2001
DNA adducts, strand breaks and micronuclei in mice exposed to styrene by inhalation. Chemico-biological interactions, 2001, Sep-28, Volume: 137, Issue:3 Topics: Administration, Inhalation; Animals; Bone Marrow Cells; Comet Assay; DNA; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Erythrocytes; Hepatocytes; Lung; Lymphocytes; Male; Mice; Micronuclei, Chromosome-Defective; Mutagens; Styrene	2001
Polymorphism of xenobiotic-metabolizing enzymes and excretion of styrene-specific mercapturic acids. Chemical research in toxicology, 2001, Volume: 14, Issue:10 Topics: Acetylcysteine; Adult; Biomarkers; Carcinogens; Catalysis; Chromatography, High Pressure Liquid; Epoxide Hydrolases; Epoxy Compounds; Female; Free Radical Scavengers; Glutathione Transferase; Humans; Isoenzymes; Male; Mass Spectrometry; Occupational Exposure; Polymorphism, Genetic; Styrene; Xenobiotics	2001
Physiological modeling of the relative contributions of styrene-7,8-oxide derived from direct inhalation and from styrene metabolism to the systemic dose in humans. Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 64, Issue:2 Topics: Air Pollutants, Occupational; Air Pollution, Indoor; Epoxide Hydrolases; Epoxy Compounds; Humans; Inhalation Exposure; Liver; Models, Biological; Occupational Exposure; Plastics; Styrene	2001
Estimation of a possible tumorigenic risk of styrene from daily intake via food and ambient air. Toxicology letters, 2002, Jan-05, Volume: 126, Issue:1 Topics: Adult; Air Pollutants; Animals; Dose-Response Relationship, Drug; Epoxy Compounds; Food Contamination; Humans; Lung Neoplasms; Male; Mice; Models, Biological; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Risk Assessment; Styrene	2002
DNA adducts of styrene-7,8-oxide in target and non-target organs for tumor induction in rat and mouse after repeated inhalation exposure to styrene. Mutation research, 2002, Mar-20, Volume: 500, Issue:1-2 Topics: Administration, Inhalation; Animals; Carcinogens; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Female; Isomerism; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mutagens; Rats; Styrene	2002
Physiologically based pharmacokinetic modeling of styrene and styrene oxide respiratory-tract dosimetry in rodents and humans. Inhalation toxicology, 2002, Volume: 14, Issue:8 Topics: Animals; Carcinogens; Epoxy Compounds; Forecasting; Humans; Inhalation Exposure; Liver; Mice; Models, Biological; Rats; Respiratory System; Styrene; Tissue Distribution	2002
Pilot-scale production of (S)-styrene oxide from styrene by recombinant Escherichia coli synthesizing styrene monooxygenase. Biotechnology and bioengineering, 2002, Oct-05, Volume: 80, Issue:1 Topics: Cell Line; Epoxy Compounds; Escherichia coli; Gene Expression Regulation, Bacterial; Oxygenases; Pilot Projects; Pseudomonas; Recombination, Genetic; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Styrene	2002
Toxicity screening by electrochemical detection of DNA damage by metabolites generated in situ in ultrathin DNA-enzyme films. Journal of the American Chemical Society, 2003, Feb-05, Volume: 125, Issue:5 Topics: Biosensing Techniques; Camphor 5-Monooxygenase; DNA Adducts; DNA Damage; Electrochemistry; Epoxy Compounds; Hydrogen Peroxide; Kinetics; Mutagenicity Tests; Myoglobin; Styrene	2003
A toxicokinetic model for styrene and its metabolite styrene-7,8-oxide in mouse, rat and human with special emphasis on the lung. Toxicology letters, 2003, Feb-18, Volume: 138, Issue:1-2 Topics: Administration, Inhalation; Animals; Carcinogens; DNA Adducts; Epoxy Compounds; Hemoglobins; Humans; Lung; Mice; Models, Biological; Rats; Species Specificity; Styrene	2003
In vitro metabolism of styrene to styrene oxide in liver and lung of Cyp2E1 knockout mice. Journal of toxicology and environmental health. Part A, 2003, May-09, Volume: 66, Issue:9 Topics: Animals; Cytochrome P-450 CYP2E1; Environmental Pollutants; Epoxy Compounds; Liver; Lung; Male; Mice; Mice, Knockout; Styrene	2003
Refinements to physiologically-based pharmacokinetic model for styrene. Toxicology letters, 2003, Sep-30, Volume: 144, Issue:2 Topics: Animals; Data Interpretation, Statistical; Epoxy Compounds; Humans; Lung; Mice; Models, Biological; Occupational Exposure; Rats; Styrene	2003
Comparison of the susceptibility of wild-type and CYP2E1 knockout mice to the hepatotoxic and pneumotoxic effects of styrene and styrene oxide. Toxicology letters, 2004, May-02, Volume: 150, Issue:3 Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Cytochrome P-450 CYP2E1; Epoxy Compounds; Injections, Intraperitoneal; L-Iditol 2-Dehydrogenase; Liver; Lung; Mice; Mice, Inbred Strains; Mice, Knockout; Styrene	2004
Biochemical characterization of StyAB from Pseudomonas sp. strain VLB120 as a two-component flavin-diffusible monooxygenase. Journal of bacteriology, 2004, Volume: 186, Issue:16 Topics: Cloning, Molecular; Dimerization; Electron Transport; Epoxy Compounds; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; FMN Reductase; Molecular Weight; NAD; Oxygenases; Protein Subunits; Pseudomonas; Recombinant Proteins; Riboflavin; Styrene; Substrate Specificity	2004
Comparison of the depletion of glutathione in mouse liver and lung following administration of styrene and its metabolites styrene oxide and 4-vinylphenol. Toxicology, 2005, Jan-31, Volume: 206, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Epoxy Compounds; Glutathione; Liver; Lung; Male; Mice; Mice, Inbred ICR; Phenols; Styrene	2005
Multistate reactivity in styrene epoxidation by compound I of cytochrome p450: mechanisms of products and side products formation. Chemistry (Weinheim an der Bergstrasse, Germany), 2005, Apr-22, Volume: 11, Issue:9 Topics: Cytochrome P-450 Enzyme System; Epoxy Compounds; Models, Molecular; Oxidation-Reduction; Porphyrins; Quantum Theory; Styrene	2005
Effects of styrene and its metabolites on different lung compartments of the mouse--cell proliferation and histomorphology. Regulatory toxicology and pharmacology : RTP, 2005, Volume: 42, Issue:1 Topics: Acetaldehyde; Animals; Apoptosis; Benzyl Alcohols; Bronchi; Cell Proliferation; Epoxy Compounds; Female; Glutathione; Humans; Injections, Intraperitoneal; Male; Mice; Phenols; Phenylacetates; Phenylethyl Alcohol; Styrene	2005
Styrene-7,8-oxide burden in ventilated, perfused lungs of mice and rats exposed to vaporous styrene. Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 90, Issue:1 Topics: Administration, Inhalation; Air Pollutants, Occupational; Animals; Dose-Response Relationship, Drug; Drug Residues; Epoxy Compounds; Gases; In Vitro Techniques; Inhalation Exposure; Lung; Male; Mice; Mice, Inbred Strains; Perfusion; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Styrene	2006
Styrene monomer primarily induces CYP2B1 mRNA in rat liver. Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:12 Topics: Animals; Biotransformation; Blotting, Western; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Induction; Epoxide Hydrolases; Epoxy Compounds; Inactivation, Metabolic; Liver; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Styrene	2005
Predictors of occupational exposure to styrene and styrene-7,8-oxide in the reinforced plastics industry. Occupational and environmental medicine, 2006, Volume: 63, Issue:10 Topics: Adolescent; Adult; Air Pollutants, Occupational; Air Pollution, Indoor; Biomarkers; Carcinogens; Environmental Monitoring; Epoxy Compounds; Female; Glass; Humans; Industry; Male; Middle Aged; Multivariate Analysis; Occupational Exposure; Plastics; Predictive Value of Tests; Styrene	2006
The efficiency of recombinant Escherichia coli as biocatalyst for stereospecific epoxidation. Biotechnology and bioengineering, 2006, Oct-20, Volume: 95, Issue:3 Topics: Biotransformation; Catalysis; Cell Membrane Permeability; Epoxy Compounds; Escherichia coli; Genetic Vectors; Kinetics; Oxygenases; Styrene	2006
Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells. Toxicology, 2006, Sep-21, Volume: 226, Issue:2-3 Topics: Acetylcysteine; Animals; Animals, Genetically Modified; Biotransformation; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Enzyme Inhibitors; Epoxide Hydrolases; Epoxy Compounds; Glutathione; Humans; Styrene; Styrenes	2006
Comparison of styrene and its metabolites styrene oxide and 4-vinylphenol on cytotoxicity and glutathione depletion in Clara cells of mice and rats. Toxicology, 2006, Oct-03, Volume: 227, Issue:1-2 Topics: Animals; Cell Survival; Cells, Cultured; Epoxy Compounds; Glutathione; Lung; Male; Mice; Mice, Inbred Strains; Phenols; Rats; Rats, Sprague-Dawley; Species Specificity; Stereoisomerism; Styrene	2006
Effects of styrene and styrene oxide on glutathione-related antioxidant enzymes. Toxicology, 2006, Oct-29, Volume: 227, Issue:3 Topics: Animals; Antioxidants; Dipeptides; Environmental Pollutants; Epoxy Compounds; Glutathione; Glutathione Reductase; Lipid Peroxidation; Lipid Peroxides; Liver; Lung; Mice; Mice, Inbred Strains; Styrene	2006
Styrene-oxide N-terminal valine haemoglobin adducts in reinforced plastic workers: possible influence of genetic polymorphism of drug-metabolising enzymes. Toxicology, 2007, Jul-31, Volume: 237, Issue:1-3 Topics: Adult; Air Pollutants, Occupational; Biomarkers; Chemical Industry; Enzymes; Epoxy Compounds; Female; Glyoxylates; Hemoglobins; Humans; Inactivation, Metabolic; Male; Mandelic Acids; Occupational Exposure; Polymorphism, Genetic; Styrene; Valine; Workplace	2007
Styrene-oxide N-terminal valine haemoglobin adducts as biomarkers of occupational exposure to styrene. International journal of hygiene and environmental health, 2008, Volume: 211, Issue:1-2 Topics: Adolescent; Adult; Air Pollutants, Occupational; Biomarkers; Case-Control Studies; Epoxy Compounds; Female; Hemoglobins; Humans; Male; Middle Aged; Occupational Exposure; Sensitivity and Specificity; Styrene; Valine	2008
Microbial biofilms: new catalysts for maximizing productivity of long-term biotransformations. Biotechnology and bioengineering, 2007, Dec-15, Volume: 98, Issue:6 Topics: Biofilms; Bioreactors; Biotechnology; Biotransformation; Catalysis; Epoxy Compounds; Pseudomonas; Styrene; Time Factors	2007
An integrated approach to biomonitoring exposure to styrene and styrene-(7,8)-oxide using a repeated measurements sampling design. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2008, Volume: 13, Issue:6 Topics: Acetylcysteine; Adult; Air Pollutants, Occupational; Biomarkers; Biotransformation; Chemical Industry; Environmental Monitoring; Epoxy Compounds; Ethylene Glycols; Female; Glutathione Transferase; Hemoglobins; Humans; Male; Middle Aged; Occupational Exposure; Phenols; Polymorphism, Genetic; Serum Albumin; Smoking; Styrene	2008
Investigation on the mechanisms of genotoxicity of butadiene, styrene and their combination in human lymphocytes using the Comet assay. Mutation research, 2009, May-12, Volume: 664, Issue:1-2 Topics: Adult; Butadienes; Cohort Studies; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Female; Humans; In Vitro Techniques; Lymphocytes; Male; Mutagens; Occupational Exposure; Reactive Oxygen Species; Rubber; Styrene	2009
Effect of multiple doses of styrene and R-styrene oxide on CC10, bax, and bcl-2 expression in isolated Clara cells of CD-1 mice. Toxicology, 2009, May-17, Volume: 259, Issue:3 Topics: Animals; bcl-2-Associated X Protein; Blotting, Western; Epithelial Cells; Epoxy Compounds; Lung; Lung Neoplasms; Male; Mice; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Styrene; Uteroglobin	2009
Identification of a novel self-sufficient styrene monooxygenase from Rhodococcus opacus 1CP. Journal of bacteriology, 2009, Volume: 191, Issue:15 Topics: Bacterial Proteins; Chromatography, High Pressure Liquid; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Genome, Bacterial; Models, Biological; Molecular Sequence Data; Oxygenases; Phylogeny; Recombinant Proteins; Rhodococcus; Styrene	2009
Indicators of oxidative stress and apoptosis in mouse whole lung and Clara cells following exposure to styrene and its metabolites. Toxicology, 2009, Oct-29, Volume: 264, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; bcl-2-Associated X Protein; Biomarkers; Carcinogens; Caspase 3; Caspase 8; Cells, Cultured; Deoxyguanosine; Epithelial Cells; Epoxy Compounds; Injections, Intraperitoneal; Lung; Male; Mice; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; RNA, Messenger; Styrene; Superoxide Dismutase; Time Factors	2009
Depletion by styrene of glutathione in plasma and bronchioalveolar lavage fluid of non-Swiss albino (NSA) mice. Journal of toxicology and environmental health. Part A, 2010, Volume: 73, Issue:11 Topics: Air Pollutants, Occupational; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Epoxy Compounds; Glutathione; Injections, Intraperitoneal; Lung; Male; Mice; Oxidative Stress; Styrene; Time Factors	2010
Evidence for cellular protein covalent binding derived from styrene metabolite. Chemico-biological interactions, 2010, Aug-05, Volume: 186, Issue:3 Topics: Animals; Cell Line; Cytochrome P-450 CYP2E1; Cytotoxins; Epoxy Compounds; Humans; Male; Mice; Protein Binding; Proteins; Styrene	2010
Low temperature photo-oxidation of chloroperoxidase Compound II. Journal of inorganic biochemistry, 2010, Volume: 104, Issue:11 Topics: Chloride Peroxidase; Cold Temperature; Electron Spin Resonance Spectroscopy; Epoxy Compounds; Heme; Hydrogen-Ion Concentration; Iron; Kinetics; Oxidants; Oxidation-Reduction; Peroxynitrous Acid; Photochemical Processes; Photolysis; Reactive Oxygen Species; Solvents; Spectrophotometry, Ultraviolet; Styrene; Temperature	2010
Metabolism and toxicity of styrene in microsomal epoxide hydrolase-deficient mice. Journal of toxicology and environmental health. Part A, 2010, Volume: 73, Issue:24 Topics: Animals; Bronchi; Bronchoalveolar Lavage Fluid; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Epoxide Hydrolases; Epoxy Compounds; Glutathione; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Microsomes; Styrene; Time Factors	2010
Hepatotoxicity and pneumotoxicity of styrene and its metabolites in glutathione S-transferase-deficient mice. Drug and chemical toxicology, 2011, Volume: 34, Issue:4 Topics: Animals; Bronchoalveolar Lavage Fluid; Data Interpretation, Statistical; Epoxy Compounds; Glutathione; Glutathione Transferase; Inactivation, Metabolic; Liver; Lung; Mice; Mice, Knockout; Oxidative Stress; Phenols; Styrene	2011
CYP2F2-generated metabolites, not styrene oxide, are a key event mediating the mode of action of styrene-induced mouse lung tumors. Regulatory toxicology and pharmacology : RTP, 2012, Volume: 62, Issue:1 Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Epoxy Compounds; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Styrene	2012
Modification of the metabolism and toxicity of styrene and styrene oxide in hepatic cytochrome P450 reductase deficient mice and CYP2F2 deficient mice. Toxicology, 2012, Apr-11, Volume: 294, Issue:2-3 Topics: Animals; Bronchoalveolar Lavage Fluid; Cytochrome P-450 Enzyme System; Epoxy Compounds; Glutathione; L-Iditol 2-Dehydrogenase; Liver; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH-Ferrihemoprotein Reductase; Styrene	2012
Simultaneous determination of aromatic acid metabolites of styrene and styrene-oxide in rat urine by gas chromatography-flame ionization detection. Journal of analytical toxicology, 2012, Volume: 36, Issue:5 Topics: Acids, Carbocyclic; Administration, Inhalation; Animals; Benzoic Acid; Epoxy Compounds; Flame Ionization; Glyoxylates; Hippurates; Inhalation Exposure; Limit of Detection; Male; Mandelic Acids; Phenylacetates; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Reproducibility of Results; Styrene; Urinalysis	2012
Genotoxicity of styrene-7,8-oxide and styrene in Fisher 344 rats: a 4-week inhalation study. Toxicology letters, 2012, Jun-20, Volume: 211, Issue:3 Topics: Administration, Inhalation; Animals; Atmosphere Exposure Chambers; Blood Cell Count; Comet Assay; DNA Breaks; DNA Glycosylases; Epoxy Compounds; Erythrocytes; Male; Micronucleus Tests; Mutagens; Rats; Rats, Inbred F344; Reticulocytes; Styrene	2012
Production host selection for asymmetric styrene epoxidation: Escherichia coli vs. solvent-tolerant Pseudomonas. Journal of industrial microbiology & biotechnology, 2012, Volume: 39, Issue:8 Topics: Biocatalysis; Bioreactors; Biotransformation; Epoxy Compounds; Escherichia coli; Glucose; Isomerases; Oxygenases; Pseudomonas; Solvents; Styrene	2012
Studies of styrene, styrene oxide and 4-hydroxystyrene toxicity in CYP2F2 knockout and CYP2F1 humanized mice support lack of human relevance for mouse lung tumors. Regulatory toxicology and pharmacology : RTP, 2013, Volume: 66, Issue:1 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cell Proliferation; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Epoxy Compounds; Female; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Oxidoreductases, N-Demethylating; Phenols; Species Specificity; Styrene	2013
Metabolism of styrene to styrene oxide and vinylphenols in cytochrome P450 2F2- and P450 2E1-knockout mouse liver and lung microsomes. Chemical research in toxicology, 2014, Jan-21, Volume: 27, Issue:1 Topics: Animals; Cytochrome P-450 Enzyme System; Epoxy Compounds; Lung; Mice; Mice, Knockout; Microsomes; Microsomes, Liver; Molecular Structure; Phenols; Styrene	2014
Segmented flow is controlling growth of catalytic biofilms in continuous multiphase microreactors. Biotechnology and bioengineering, 2014, Volume: 111, Issue:9 Topics: Biofilms; Bioreactors; Culture Media; Epoxy Compounds; Pseudomonas; Rheology; Styrene	2014
Engineering of Pseudomonas taiwanensis VLB120 for constitutive solvent tolerance and increased specific styrene epoxidation activity. Applied and environmental microbiology, 2014, Volume: 80, Issue:20 Topics: Bacterial Proteins; Biocatalysis; Drug Resistance, Bacterial; Epoxy Compounds; Gene Deletion; Genetic Engineering; Molecular Sequence Data; Pseudomonas; Solvents; Styrene	2014
An evaluation of concentrations of styrene-7,8-oxide in rats and humans resulting from exposure to styrene or styrene-7,8-oxide and potential genotoxicity. Toxicology letters, 2016, Apr-15, Volume: 247 Topics: Administration, Inhalation; Adult; Animals; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Female; Humans; Male; Models, Molecular; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Risk Factors; Styrene; Toxicity Tests	2016
[Optimization of primary hepatocytes model and study on the cytotoxicity of styrene and styrene oxide]. Wei sheng yan jiu = Journal of hygiene research, 2016, Volume: 45, Issue:3 Topics: Alanine Transaminase; Albumins; Animals; Cell Culture Techniques; Cell Survival; Cells, Cultured; Epoxy Compounds; Hepatocytes; L-Lactate Dehydrogenase; Mice; Mice, Inbred BALB C; Styrene	2016
Evidential Proximity, Independence, and the evaluation of carcinogenicity. Journal of evaluation in clinical practice, 2019, Volume: 25, Issue:6 Topics: Biomedical Research; Carcinogenesis; Carcinogens; Causality; Epoxy Compounds; Humans; International Agencies; Knowledge; Neoplasms; Philosophy, Medical; Public Health; Styrene	2019
Production of styrene oxide from styrene by a recombinant Bioscience, biotechnology, and biochemistry, 2020, Volume: 84, Issue:7 Topics: Bacterial Outer Membrane Proteins; Biocatalysis; Carrier Proteins; Cyclohexanes; Epoxy Compounds; Escherichia coli; Escherichia coli Proteins; Hexanes; Lipoproteins; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Oxygenases; Plasmids; Pseudomonas putida; Signal Transduction; Solvents; Styrene	2020
A Highly Efficient Heterogeneous Catalyst of Bimetal-Organic Frameworks for the Epoxidation of Olefin with H Molecules (Basel, Switzerland), 2020, May-21, Volume: 25, Issue:10 Topics: Alkenes; Catalysis; Copper; Epoxy Compounds; Hydrogen Peroxide; Metal-Organic Frameworks; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Styrene; X-Ray Diffraction	2020
Influence of LiTaO Chemphyschem : a European journal of chemical physics and physical chemistry, 2022, 12-16, Volume: 23, Issue:24 Topics: Adsorption; Density Functional Theory; Oxygen; Quantum Theory; Styrene	2022