strontium-radioisotopes has been researched along with rubidium-chloride* in 2 studies
2 other study(ies) available for strontium-radioisotopes and rubidium-chloride
Article | Year |
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82Sr purification procedure using Chelex-100 resin.
(82)Rb is a positron-emitting radionuclide widely used in nuclear cardiology. One great advantage is its availability through a generator loaded with (82)Sr. (82)Sr can be produced in a high energy cyclotron by irradiating rubidium chloride target with proton beam. In this paper, we present an extensive study (elution profiles, effect of the elution flow rate) on the use of Chelex-100 resin and ammonia buffer. No significant effect of flow rate was evidenced between 1 and 10mL/min leading us to propose a purification process which can be easily automated. Topics: Chlorides; Chromatography, Ion Exchange; Coronary Artery Disease; Cyclotrons; Electrons; Humans; Radionuclide Generators; Radionuclide Imaging; Radiopharmaceuticals; Resins, Synthetic; Rubidium; Strontium Radioisotopes | 2013 |
Manufacture of strontium-82/rubidium-82 generators and quality control of rubidium-82 chloride for myocardial perfusion imaging in patients using positron emission tomography.
We describe a protocol to manufacture 82Sr/82Rb generators and 82RbCl for myocardial imaging with PET. The generators are manufactured in 3 stages: (1) preparation of a tin oxide column, (2) leak test of the generator column and (3) loading of the generator with 82Sr. The generators produced sterile and non-pyrogenic 82RbCl for i.v. injection. No significant 82Sr/85Sr breakthroughs were observed after elution with 20 1 of saline. The automated system delivered human doses of 82RbCl accurately. Topics: Chlorides; Coronary Disease; Heart; Humans; Quality Control; Radiation Protection; Radionuclide Generators; Rubidium; Rubidium Radioisotopes; Strontium Radioisotopes; Tomography, Emission-Computed | 1999 |