stiripentol has been researched along with clobazam in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.57) | 18.2507 |
| 2000's | 5 (17.86) | 29.6817 |
| 2010's | 17 (60.71) | 24.3611 |
| 2020's | 5 (17.86) | 2.80 |
| Authors | Studies |
|---|---|
| Grippo, J | 1 |
| Chiron, C; d'Athis, P; Dulac, O; Marchand, MC; Pons, G; Rey, E; Tran, A; Vincent, J | 1 |
| Dulac, O | 1 |
| Chiron, C; Dellatolas, G; Dulac, O; Pons, G; Rey, E; Thanh, TN; Vincent, J | 1 |
| Chiron, C; Giraud, C; Pons, G; Rey, E; Tran, A; Treluyer, JM; Vincent, J | 1 |
| Baba, H; Fukushima, K; Ikeda, S; Inoue, Y; Oguni, H; Ohtani, H; Ohtsuka, Y; Takahashi, Y; Tohyama, J | 1 |
| Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N; Trojnar, MK | 1 |
| Cao, D; Inoue, Y; Ogiwara, I; Ohtani, H; Ohtani, S; Takahashi, Y; Yamakawa, K | 1 |
| Chiron, C; Nabbout, R | 1 |
| Chancharme, L; Chugani, H; de Menezes, MS; Devinsky, O; Franz, DN; Hamiwka, L; Hernandez, A; Laux, L; Le Guern, ME; Mikati, MA; Morse, RP; Saneto, RP; Sullivan, J; Valencia, I; Wirrell, EC | 1 |
| Inoue, Y; Ohtsuka, Y | 2 |
| Boor, R; Reese, JP; Rosenow, F; Schubert-Bast, S; Stephani, U; Strzelczyk, A | 1 |
| Aarons, L; Ogungbenro, K | 1 |
| Chhun, S; Chiron, C; Dulac, O; Jullien, V; Pons, G; Rey, E; Tod, M | 1 |
| Specchio, N; Trivisano, M; Vigevano, F | 1 |
| Benninger, F; Dressler, A; Feucht, M; Grassl, R; Gröppel, G; Mühlebner, A; Reiter-Fink, E; Reithofer, E; Trimmel-Schwahofer, P | 1 |
| Aras, LM; Isla, J; Mingorance-Le Meur, A | 1 |
| Barnerias, C; Chemaly, N; Chiron, C; De Liso, P; Desguerre, I; Dulac, O; Hully, M; Laschet, J; Leunen, D; Nabbout, R | 1 |
| Fukuda, M; Imai, K; Inoue, Y; Jogamoto, T; Ohtsuka, Y; Suzuki, Y; Takahashi, Y; Yamamoto, Y | 1 |
| Clifford, T; Coyle, D; Elliott, J; McCoy, B; Wells, GA | 1 |
| Boyd, B; Farfel, GM; Galer, BS; Gammaitoni, A; Smith, S | 1 |
| Blakey, G; Crockett, J; Morrison, G; Sommerville, K | 1 |
| Ikeda, H; Imai, K; Inoue, Y; Kagawa, Y; Takahashi, Y; Yamamoto, Y | 1 |
| Bjørnvold, M; Burns, ML; Heger, K; Johannessen Landmark, C; Johannessen, SI; Lund, C; Sætre, E | 1 |
| Critchley, D; Gidal, B; Morrison, G; Patsalos, PN; Szaflarski, JP; VanLandingham, K | 1 |
| García-Peñas, JJ; Gil Nagel-Rein, A; Sánchez-Carpintero, R; Villanueva-Haba, V | 1 |
| Vasquez, A; Wirrell, EC; Youssef, PE | 1 |
6 review(s) available for stiripentol and clobazam
| Article | Year |
|---|---|
[Treatment of the epilepsy: new drugs].
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide | 1996 |
Epileptic encephalopathy.
Topics: Adolescent; Age Factors; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Brain Diseases; Child; Child, Preschool; Clobazam; Dioxolanes; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Humans; Infant; Infant, Newborn; Landau-Kleffner Syndrome; Spasms, Infantile; Treatment Outcome | 2001 |
Stiripentol: an example of antiepileptic drug development in childhood epilepsies.
Topics: Anticonvulsants; Benzodiazepines; Child; Clobazam; Cytochrome P-450 Enzyme System; Dioxolanes; Epilepsy; Humans; Randomized Controlled Trials as Topic | 2012 |
Clinical implications of trials investigating drug-drug interactions between cannabidiol and enzyme inducers or inhibitors or common antiseizure drugs.
Topics: Anticonvulsants; Cannabidiol; Clinical Trials as Topic; Clobazam; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C19 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsies, Myoclonic; Fatty Acids, Monounsaturated; Humans; Lennox Gastaut Syndrome; Valproic Acid | 2020 |
Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain.
Topics: Anticonvulsants; Cannabidiol; Clobazam; Clonazepam; Diazepam; Dioxolanes; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Epilepsies, Myoclonic; Humans; Lennox Gastaut Syndrome; Phenobarbital; Practice Guidelines as Topic; Pyrrolidinones; Spain; Triazoles; Valproic Acid | 2021 |
Stiripentol for the treatment of seizures associated with Dravet syndrome in patients 6 months and older and taking clobazam.
Topics: Anticonvulsants; Child; Child, Preschool; Clobazam; Epilepsies, Myoclonic; Humans; Observational Studies as Topic; Randomized Controlled Trials as Topic; Seizures | 2023 |
6 trial(s) available for stiripentol and clobazam
| Article | Year |
|---|---|
Stiripentol in severe myoclonic epilepsy in infancy: a randomised placebo-controlled syndrome-dedicated trial. STICLO study group.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Child, Preschool; Clobazam; Dioxolanes; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Infant; Male; Syndrome; Valproic Acid | 2000 |
[Long-term efficacy and tolerance of stiripentaol in severe myoclonic epilepsy of infancy (Dravet's syndrome)].
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Child, Preschool; Clobazam; Dioxolanes; Epilepsies, Myoclonic; Female; Humans; Infant; Male; Severity of Illness Index; Treatment Outcome; Valproic Acid | 2002 |
Effectiveness of add-on stiripentol to clobazam and valproate in Japanese patients with Dravet syndrome: additional supportive evidence.
Topics: Adolescent; Adult; Anticonvulsants; Asian People; Benzodiazepines; Child; Child, Preschool; Clobazam; Dioxolanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Infant; Japan; Male; Treatment Outcome; Valproic Acid; Young Adult | 2014 |
Long-term safety and efficacy of stiripentol for the treatment of Dravet syndrome: A multicenter, open-label study in Japan.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam; Dioxolanes; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Infant; Japan; Male; Treatment Outcome; Valproic Acid; Young Adult | 2015 |
A phase I, randomized, open-label, single-dose, 3-period crossover study to evaluate the drug-drug interaction between ZX008 (fenfluramine HCl oral solution) and a regimen of stiripentol, clobazam, and valproate in healthy subjects
.
Topics: Administration, Oral; Adult; Clobazam; Cross-Over Studies; Dioxolanes; Drug Interactions; Female; Fenfluramine; Healthy Volunteers; Humans; Male; Middle Aged; Non-Smokers; Valproic Acid; Young Adult | 2019 |
A Phase 1, Open-Label, Pharmacokinetic Trial to Investigate Possible Drug-Drug Interactions Between Clobazam, Stiripentol, or Valproate and Cannabidiol in Healthy Subjects.
Topics: Adult; Anticonvulsants; Cannabidiol; Clobazam; Cytochrome P-450 CYP2C19; Dioxolanes; Drug Interactions; Female; Genotype; Healthy Volunteers; Humans; Male; Valproic Acid | 2019 |
16 other study(ies) available for stiripentol and clobazam
| Article | Year |
|---|---|
In vitro and in vivo inhibitory effect of stiripentol on clobazam metabolism.
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Benzodiazepines; Clinical Trials as Topic; Clobazam; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dioxolanes; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Ketoconazole; Mixed Function Oxygenases; Omeprazole; Recombinant Proteins | 2006 |
Stiripentol open study in Japanese patients with Dravet syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Benzodiazepines; Child; Child, Preschool; Clobazam; Cytochrome P-450 CYP2C19; Dioxolanes; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Medical Records; Middle Aged; Retrospective Studies; Syndrome; Treatment Outcome | 2009 |
Interactions of stiripentol with clobazam and valproate in the mouse maximal electroshock-induced seizure model.
Topics: Analysis of Variance; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Benzodiazepines; Brain Chemistry; Clobazam; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Hand Strength; Male; Mice; Motor Activity; Seizures; Valproic Acid | 2010 |
Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome.
Topics: Age Factors; Animals; Anticonvulsants; Benzodiazepines; Clobazam; Dioxolanes; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Genetic Predisposition to Disease; Hyperthermia, Induced; Mice; Mice, Transgenic; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Seizures; Sodium Channels | 2012 |
Stiripentol in Dravet syndrome: results of a retrospective U.S. study.
Topics: Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam; Dioxolanes; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Infant; Male; Retrospective Studies; Seizures; Treatment Outcome; United States; Valproic Acid | 2013 |
Evaluation of health-care utilization in patients with Dravet syndrome and on adjunctive treatment with stiripentol and clobazam.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam; Dioxolanes; Epilepsies, Myoclonic; Female; Health Care Costs; Health Services; Hospitalization; Humans; Male; Patient Acceptance of Health Care; Treatment Outcome; Young Adult | 2014 |
A physiologically based pharmacokinetic model for clobazam and stiripentol in adults and children.
Topics: Adult; Anticonvulsants; Benzodiazepines; Child; Clobazam; Computer Simulation; Dioxolanes; Drug Interactions; Drug Therapy, Combination; Humans; Metabolic Clearance Rate; Models, Biological; Tissue Distribution | 2015 |
Pharmacokinetics of clobazam and N-desmethylclobazam in children with dravet syndrome receiving concomitant stiripentol and valproic Acid.
Topics: Anticonvulsants; Benzodiazepines; Body Weight; Child; Child, Preschool; Clobazam; Dioxolanes; Drug Interactions; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Male; Prospective Studies; Randomized Controlled Trials as Topic; Valproic Acid | 2015 |
Extending the use of stiripentol to other epileptic syndromes: a case of PCDH19-related epilepsy.
Topics: Age of Onset; Anticonvulsants; Autistic Disorder; Benzodiazepines; Cadherins; Child; Clobazam; Cognition Disorders; Dioxolanes; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsy; Female; Fever; Humans; Intellectual Disability; Protocadherins; Syndrome; Treatment Outcome; Valproic Acid | 2015 |
Efficacy and tolerability of the ketogenic diet in Dravet syndrome - Comparison with various standard antiepileptic drug regimen.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Bromides; Child; Child, Preschool; Clobazam; Diet, Ketogenic; Dioxolanes; Epilepsies, Myoclonic; Female; Fructose; Humans; Infant; Levetiracetam; Male; Piracetam; Retrospective Studies; Seizures; Topiramate; Treatment Outcome; Vagus Nerve Stimulation; Valproic Acid; Young Adult | 2015 |
The European patient with Dravet syndrome: results from a parent-reported survey on antiepileptic drug use in the European population with Dravet syndrome.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam; Dioxolanes; Epilepsies, Myoclonic; Europe; Female; Humans; Male; NAV1.1 Voltage-Gated Sodium Channel; Sodium Channel Blockers; Valproic Acid | 2015 |
Patients with dravet syndrome in the era of stiripentol: A French cohort cross-sectional study.
Topics: Adolescent; Age Factors; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam; Cross-Sectional Studies; Dioxolanes; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Follow-Up Studies; France; Humans; Male; NAV1.1 Voltage-Gated Sodium Channel; Severity of Illness Index; Treatment Failure; Valproic Acid; Young Adult | 2016 |
Add-on stiripentol elevates serum valproate levels in patients with or without concomitant topiramate therapy.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Dioxolanes; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Fructose; Humans; Infant; Male; Polymorphism, Genetic; Retrospective Studies; Topiramate; Valproic Acid | 2017 |
Economic Evaluation of Stiripentol for Dravet Syndrome: A Cost-Utility Analysis.
Topics: Anticonvulsants; Canada; Child; Clobazam; Cost-Benefit Analysis; Dioxolanes; Drug Therapy, Combination; Epilepsies, Myoclonic; Humans; Quality-Adjusted Life Years; Valproic Acid | 2018 |
Impact of CYP2C19 Phenotypes on Clinical Efficacy of Stiripentol in Japanese Patients With Dravet Syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Asian People; Child; Child, Preschool; Clobazam; Cytochrome P-450 CYP2C19; Dioxolanes; Drug Interactions; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Infant; Japan; Male; Retrospective Studies; Valproic Acid; Young Adult | 2020 |
Pharmacokinetic Variability During Long-Term Therapeutic Drug Monitoring of Valproate, Clobazam, and Levetiracetam in Patients With Dravet Syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam; Dioxolanes; Drug Monitoring; Epilepsies, Myoclonic; Epilepsy; Female; Humans; Levetiracetam; Male; Middle Aged; Norway; Retrospective Studies; Valproic Acid; Young Adult | 2020 |