stilbenes and quinoline

stilbenes has been researched along with quinoline* in 1 studies

Other Studies

1 other study(ies) available for stilbenes and quinoline

Article	Year
A new family of quinoline and quinoxaline analogues of combretastatins. Bioorganic & medicinal chemistry letters, 2004, Jul-16, Volume: 14, Issue:14 The 3-hydroxy-4-methoxyphenyl ring of combretastatin A-4 can be replaced by a 2-naphthyl moiety without significant loss of cytotoxicity and inhibition of tubulin polymerization potency. In this paper we show that the 6- or 7-quinolyl systems can in turn replace both cyclic moieties, keeping in the first case most of the potency as cytotoxic agent and in the second case as inhibitor of tubulin polymerization, related to the activities displayed by model compounds. Topics: Antineoplastic Agents; Biopolymers; Cell Line, Tumor; Humans; Inhibitory Concentration 50; Ligands; Naphthalenes; Quinolines; Quinoxalines; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators	2004

Article

Year

A new family of quinoline and quinoxaline analogues of combretastatins.

Bioorganic & medicinal chemistry letters, 2004, Jul-16, Volume: 14, Issue:14

The 3-hydroxy-4-methoxyphenyl ring of combretastatin A-4 can be replaced by a 2-naphthyl moiety without significant loss of cytotoxicity and inhibition of tubulin polymerization potency. In this paper we show that the 6- or 7-quinolyl systems can in turn replace both cyclic moieties, keeping in the first case most of the potency as cytotoxic agent and in the second case as inhibitor of tubulin polymerization, related to the activities displayed by model compounds.

Topics: Antineoplastic Agents; Biopolymers; Cell Line, Tumor; Humans; Inhibitory Concentration 50; Ligands; Naphthalenes; Quinolines; Quinoxalines; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2004