stilbenes has been researched along with carbazole* in 2 studies
2 other study(ies) available for stilbenes and carbazole
| Article | Year |
|---|---|
Execution of aggregation-induced emission as nano-sensors for hypochlorite detection and application for bioimaging in living cells and zebrafish.
Hypochlorite (ClO Topics: Animals; Biosensing Techniques; Carbazoles; Fluorescent Dyes; HeLa Cells; Humans; Hypochlorous Acid; Molecular Structure; Nanoparticles; Optical Imaging; Particle Size; Spectrometry, Fluorescence; Stilbenes; Surface Properties; Thiobarbiturates; Tumor Cells, Cultured; Zebrafish | 2020 |
Structure-activity relationships of indole compounds derived from combretastatin A4: synthesis and biological screening of 5-phenylpyrrolo[3,4-a]carbazole-1,3-diones as potential antivascular agents.
A series of 5-(3',4',5'-trimethoxyphenyl)pyrrolo[3,4-a]carbazole-1,3(2H,10H)-diones was designed as cis-restricted analogues of 3-aroylindoles, arylthioindoles and 3-benzylidoneindolin-2-ones derived from combretastatin A4 (CA-4). Starting from various indoles, compounds were synthesized by means of a convenient two-step procedure involving a one-pot multicomponent reaction as key step. Intermediate tetrahydro[3,4-a]carbazoles and their corresponding carbazoles were submitted to biological screening tests involved in antivascular action, including the cytotoxicity against murine B16 melanoma cells, the rounding up of endothelial cells (EA.hy 926) and the inhibition of tubulin polymerization. Of the 31 compounds screened, those bearing a methoxy group at the 8-position endowed significant biological activities. A carbazole compound 30 was identified as a promising candidate for further development of novel vascular targeting agents. Topics: Animals; Antineoplastic Agents; Blood Vessels; Carbazoles; Cell Line, Tumor; Drug Evaluation, Preclinical; Humans; Mice; Protein Multimerization; Protein Structure, Quaternary; Stilbenes; Structure-Activity Relationship; Tubulin | 2010 |