stigmasterol has been researched along with violaxanthin* in 1 studies
1 other study(ies) available for stigmasterol and violaxanthin
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Eustigmatophyte strains with potential interest in cancer prevention and treatment: partial chemical characterization and evaluation of cytotoxic and antioxidant activity.
The interest in bioactive compounds from microalgae is increasing since they have medicinal and nutritional areas. The present work aims to evaluate the potential pharmaceutical interest of extracts from three eustigmatophyte strains from the Coimbra Collection of Algae (ACOI): Chlorobotrys gloeothece, Chlorobotrys regularis and Characiopsis aquilonaris. Antioxidant and antiproliferative activities were determined as well as chlorophyll a, carotenoid and phenolic total contents. In addition, major pigments and sterols were identified and quantified. The three strains were grown until the stationary phase and then the biomass was extracted. Antioxidant activity was measured by TEAC, DPPH and FRAP assays and antiproliferative effect was assessed by the MTT method on MCF-7, PC-3 and NHDF cells. The pigment and phenolic total contents were determined by spectrophotometry. Of these strains, C. aquilonaris showed the highest antioxidant activity measured by TEAC and FRAP assays (23.98 ± 0.01 μmol TE eq g Topics: Antineoplastic Agents; Antioxidants; beta Carotene; Biological Factors; Cell Proliferation; Cell Survival; Chlorophyll A; Cholesterol; Humans; MCF-7 Cells; PC-3 Cells; Stigmasterol; Stramenopiles; Xanthophylls | 2021 |