stigmasterol and coumarin

stigmasterol has been researched along with coumarin* in 2 studies

Other Studies

2 other study(ies) available for stigmasterol and coumarin

Article	Year
Antitermite activities of coumarin derivatives and scopoletin from Protium javanicum Burm. f. Journal of chemical ecology, 2010, Volume: 36, Issue:7 The antitermite (termiticidal and antifeedant) activity of Protium javanicum Burm. f. extract was investigated. The ethyl acetate fraction was active. Scopoletin (1), quercetin, and stigmasterol were isolated by bioassay-guided fractionation. Scopoletin had the highest activity among the three compounds. In order to investigate the structure-activity relationship (SAR) of the methoxy and hydroxy groups at the C-6 and C-7 positions of the coumarin skeleton, we synthesized several coumarin derivatives whose chemical structures are similar to scopoletin. Scopoletin exhibited the strongest termiticidal activity among the 10 compounds tested, followed by 6-methoxycoumarin (3), 6-hydroxycoumarin (7), and umbelliferone (8). All compounds except coumarin (9) showed antifeedant activity. Topics: Animals; Burseraceae; Coumarins; Insecticides; Isoptera; Plant Extracts; Quercetin; Scopoletin; Stigmasterol; Structure-Activity Relationship; Umbelliferones	2010
Induction by carrot allelochemicals of insecticide-metabolising enzymes in the southern armyworm (Spodoptera eridania). Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 77, Issue:1 Carrot foliage monoterpenes induce cytochrome P-450 up to 2.9-fold, NADPH cytochrome c (P-450) reductase up to 1.6-fold, NADPH-oxidation up to 3.8-fold, aldrin epoxidation up to 1.5-fold in southern armyworm larval midgut tissues when incorporated in their diet at 0.2% for 3 days. Stigmasterol and ergosterol did not substantially induce microsomal oxidase activities and significantly inhibited GSH S-aryltransferase activity and sulfotransferase activity. Coumarin did not substantially affect microsomal oxidase and sulfotransferase activity but is the most potent inducer of GSH S-aryltransferase activity, increasing this activity 7-fold. None of the chemicals is acutely toxic to the sixth instar larvae or affect the larval weight gain except coumarin which significantly depressed the maximal body weight attained. Topics: Animals; Body Weight; Coumarins; Cytochrome P-450 Enzyme System; Enzyme Induction; Ergosterol; Glutathione Transferase; Insecticides; Larva; Lepidoptera; Mixed Function Oxygenases; Moths; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Stigmasterol; Sulfurtransferases; Terpenes; Vegetables	1984

Article

Year

Antitermite activities of coumarin derivatives and scopoletin from Protium javanicum Burm. f.

Journal of chemical ecology, 2010, Volume: 36, Issue:7

The antitermite (termiticidal and antifeedant) activity of Protium javanicum Burm. f. extract was investigated. The ethyl acetate fraction was active. Scopoletin (1), quercetin, and stigmasterol were isolated by bioassay-guided fractionation. Scopoletin had the highest activity among the three compounds. In order to investigate the structure-activity relationship (SAR) of the methoxy and hydroxy groups at the C-6 and C-7 positions of the coumarin skeleton, we synthesized several coumarin derivatives whose chemical structures are similar to scopoletin. Scopoletin exhibited the strongest termiticidal activity among the 10 compounds tested, followed by 6-methoxycoumarin (3), 6-hydroxycoumarin (7), and umbelliferone (8). All compounds except coumarin (9) showed antifeedant activity.

Topics: Animals; Burseraceae; Coumarins; Insecticides; Isoptera; Plant Extracts; Quercetin; Scopoletin; Stigmasterol; Structure-Activity Relationship; Umbelliferones

2010

Induction by carrot allelochemicals of insecticide-metabolising enzymes in the southern armyworm (Spodoptera eridania).

Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 77, Issue:1

Carrot foliage monoterpenes induce cytochrome P-450 up to 2.9-fold, NADPH cytochrome c (P-450) reductase up to 1.6-fold, NADPH-oxidation up to 3.8-fold, aldrin epoxidation up to 1.5-fold in southern armyworm larval midgut tissues when incorporated in their diet at 0.2% for 3 days. Stigmasterol and ergosterol did not substantially induce microsomal oxidase activities and significantly inhibited GSH S-aryltransferase activity and sulfotransferase activity. Coumarin did not substantially affect microsomal oxidase and sulfotransferase activity but is the most potent inducer of GSH S-aryltransferase activity, increasing this activity 7-fold. None of the chemicals is acutely toxic to the sixth instar larvae or affect the larval weight gain except coumarin which significantly depressed the maximal body weight attained.

Topics: Animals; Body Weight; Coumarins; Cytochrome P-450 Enzyme System; Enzyme Induction; Ergosterol; Glutathione Transferase; Insecticides; Larva; Lepidoptera; Mixed Function Oxygenases; Moths; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Stigmasterol; Sulfurtransferases; Terpenes; Vegetables

1984