stigmasterol and beta-amyrin-acetate

Phytochemical investigations of the powdered root of Hibiscus vitifolius Linn. (Malvaceae) was extracted successively with n-hexane and chloroform. Analysis of the n-hexane extract by GC-MS led to the identification of twenty-six components by comparison of their mass spectra with GC-MS library data. A novel quinolone alkaloid, vitiquinolone (5) together with eight known compounds viz. β-Amyrin acetate (1), n-octacosanol (2), β-Amyrin (3), stigmasterol (4), xanthyletin (6), alloxanthoxyletin (7), xanthoxyletin (8) and betulinic acid (9) were isolated from chloroform extract by column chromatography over silica gel. The structure of vitiquinolone was established on the basis of spectroscopic methods including UV, IR, 1D, 2D NMR and ESI-MS. The known compounds were identified on the basis of their physical and spectroscopic data as reported in the literature.

Topics: Alkaloids; Benzopyrans; Chromatography, High Pressure Liquid; Coumarins; Databases, Chemical; Ethnopharmacology; Fatty Alcohols; Flame Ionization; Gas Chromatography-Mass Spectrometry; Hibiscus; India; Medicine, Ayurvedic; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Plant Extracts; Plant Roots; Quinolones; Spectrometry, Mass, Electrospray Ionization; Stigmasterol; Triterpenes

Topics: Drugs, Chinese Herbal; Flavonoids; Oleanolic Acid; Sitosterols; Stigmasterol; Triterpenes