stevioside and glimepiride

stevioside has been researched along with glimepiride* in 1 studies

Other Studies

1 other study(ies) available for stevioside and glimepiride

Article	Year
Interaction of Organic Anion Transporter 3-Mediated Uptake of Steviol Acyl Glucuronide, a Major Metabolite of Rebaudioside A, with Selected Drugs. Journal of agricultural and food chemistry, 2020, Feb-12, Volume: 68, Issue:6 Organic anion transporter 3 (OAT3) plays a critical role in the renal excretion of many xenobiotics. Because steviol acyl glucuronide (SVAG), an OAT3 substrate, is the major circulating metabolite after oral ingestion of steviol glycosides and is excreted into the urine, inhibition of OAT3 activity may alter pharmacokinetic profiles of SVAG. The present study showed that drugs such as probenecid and glimepiride displayed potent inhibition toward the OAT3-mediated SVAG transport, with IC Topics: Animals; Biological Transport; Diterpenes, Kaurane; Glucosides; HEK293 Cells; Humans; Kidney; Male; Organic Anion Transporters, Sodium-Independent; Probenecid; Rats; Rats, Sprague-Dawley; Sulfonylurea Compounds	2020

Article

Year

Interaction of Organic Anion Transporter 3-Mediated Uptake of Steviol Acyl Glucuronide, a Major Metabolite of Rebaudioside A, with Selected Drugs.

Journal of agricultural and food chemistry, 2020, Feb-12, Volume: 68, Issue:6

Organic anion transporter 3 (OAT3) plays a critical role in the renal excretion of many xenobiotics. Because steviol acyl glucuronide (SVAG), an OAT3 substrate, is the major circulating metabolite after oral ingestion of steviol glycosides and is excreted into the urine, inhibition of OAT3 activity may alter pharmacokinetic profiles of SVAG. The present study showed that drugs such as probenecid and glimepiride displayed potent inhibition toward the OAT3-mediated SVAG transport, with IC

Topics: Animals; Biological Transport; Diterpenes, Kaurane; Glucosides; HEK293 Cells; Humans; Kidney; Male; Organic Anion Transporters, Sodium-Independent; Probenecid; Rats; Rats, Sprague-Dawley; Sulfonylurea Compounds

2020