Compounds > steganacin

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steganacin and 4-butyrolactone

steganacin has been researched along with 4-butyrolactone in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (56.25)	18.7374
1990's	2 (12.50)	18.2507
2000's	4 (25.00)	29.6817
2010's	1 (6.25)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kupchan, SM; Rebhum, LI; Wang, RW	1
Horwitz, SB; Kende, AS; Schiff, PB	1
Kende, AS; Liebeskind, LS	1
Ishiguro, T; Kishi, T; Koga, K; Komeshima, N; Mizuguchi, H; Tanida, S; Tashiro, T; Tomioka, K; Tsukagoshi, S; Tsuruo, T	1
Ishiguro, T; Koga, K; Mizuguchi, H; Tomioka, K	1
Iitaka, Y; Ishiguro, T; Koga, K; Tomioka, K	1
Gupta, RS	1
Britton, RW; Bryan, RF; Gilmore, CJ; Kupchan, SM; Restivo, RJ; Ziegler, MF	1
Horwitz, SB; Schiff, PB	1
Tomioka, K	1
Sackett, DL	1
Burnett, JC; Day, BW; Gussio, R; Hamel, E; Hermone, AR; McGrath, C; Nguyen, TL; Wipf, P; Zaharevitz, DW	1
Appukkuttan, P; Beryozkina, T; Mont, N; Van der Eycken, E	1
Cafici, L; Canonico, PL; Galli, U; Genazzani, AA; Imperio, D; Pagliai, F; Pirali, T; Sorba, G; Tron, GC	1
Appukkuttan, P; Beryozkina, T; DeMaeyer, M; Mehta, VP; Mont, N; Toppet, S; Van der Eycken, E; Van Hecke, K; Van Meervelt, L; Voet, A	1
Colobert, F; Leroux, FR; Panossian, A; Wencel-Delord, J	1

Reviews

3 review(s) available for steganacin and 4-butyrolactone

Article	Year
[Asymmetric total synthesis of some biologically active natural products]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1984, Volume: 104, Issue:10 Topics: 4-Butyrolactone; Alkaloids; Antineoplastic Agents, Phytogenic; Chemical Phenomena; Chemistry; Dioxoles; Furans; Galantamine; Lactones; Lignans; Methods; Molecular Conformation; Optical Rotation; Podophyllotoxin	1984
Podophyllotoxin, steganacin and combretastatin: natural products that bind at the colchicine site of tubulin. Pharmacology & therapeutics, 1993, Volume: 59, Issue:2 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Binding Sites; Cell Division; Lignans; Podophyllotoxin; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin	1993
Recent advances and new concepts for the synthesis of axially stereoenriched biaryls. Chemical Society reviews, 2015, Jun-07, Volume: 44, Issue:11 Topics: 4-Butyrolactone; Gossypol; Lignans; Models, Molecular; Organic Chemicals; Stereoisomerism; Vancomycin	2015

Other Studies

13 other study(ies) available for steganacin and 4-butyrolactone

Article	Year
Antimitotic and antitubulin activity of the tumor inhibitor steganacin. Cancer research, 1977, Volume: 37, Issue:9 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Binding, Competitive; Cell Division; Colchicine; Cycloparaffins; Female; Glycoproteins; Lactones; Lignans; Microtubules; Mitosis; Ovum; Podophyllotoxin; Sea Urchins; Tubulin; Tubulin Modulators; Ultracentrifugation	1977
Steganacin: an inhibitor of HeLa cell growth and microtubule assembly in vitro. Biochemical and biophysical research communications, 1978, Nov-29, Volume: 85, Issue:2 Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Cell Division; Colchicine; Cycloparaffins; HeLa Cells; Lactones; Lignans; Microtubules; Mitotic Index; Protein Binding; Structure-Activity Relationship; Tubulin	1978
Letter: Total synthesis of (+/-)-steganacin. Journal of the American Chemical Society, 1976, Jan-07, Volume: 98, Issue:1 Topics: 4-Butyrolactone; Antineoplastic Agents; Cycloparaffins; Lactones; Lignans; Methods	1976
Absolute structure-cytotoxic activity relationships of steganacin congeners and analogues. Journal of medicinal chemistry, 1991, Volume: 34, Issue:1 Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Cell Division; Humans; Indicators and Reagents; KB Cells; Lignans; Models, Molecular; Molecular Conformation; Molecular Structure; Structure-Activity Relationship	1991
Stereoselective reactions. VIII. Stereochemical requirement for the benzylic oxidation of lignan lactone. A highly selective synthesis of the antitumor lignan lactone steganacin by the oxidation of stegane. Chemical & pharmaceutical bulletin, 1985, Volume: 33, Issue:2 Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Furans; Lactones; Lignans; Oxidation-Reduction; Plant Extracts; Stereoisomerism	1985
Stereoselective reactions. XII. Synthesis of antitumor-active steganacin analogs, picrosteganol and epipicrosteganol, by selective isomerization. Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:4 Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Furans; Lactones; Lignans; Molecular Conformation; Stereoisomerism; X-Ray Diffraction	1986
Species-specific differences in toxicity of antimitotic agents toward cultured mammalian cells. Journal of the National Cancer Institute, 1985, Volume: 74, Issue:1 Topics: 4-Butyrolactone; Animals; Benzimidazoles; Biological Transport; Cells, Cultured; Colchicine; Cricetinae; Cricetulus; Griseofulvin; HeLa Cells; Humans; Lignans; Maytansine; Mice; Mitosis; Nocodazole; Podophyllotoxin; Species Specificity; Vinblastine	1985
Steganacin and steganangin, novel antileukemic lignan lactones from Steganotaenia araliacea. Journal of the American Chemical Society, 1973, Feb-21, Volume: 95, Issue:4 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Diterpenes; Lactones; Leukemia, Experimental; Lignans; Mice; Plant Extracts	1973
Taxol stabilizes microtubules in mouse fibroblast cells. Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:3 Topics: 4-Butyrolactone; Animals; Cell Movement; DNA Replication; Fibroblasts; Fluorescent Antibody Technique; HeLa Cells; Humans; Lactones; Lignans; Mice; Microtubules; Paclitaxel; Terpenes; Tubulin	1980
A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach. Journal of medicinal chemistry, 2005, Sep-22, Volume: 48, Issue:19 Topics: 2-Methoxyestradiol; 4-Butyrolactone; Aminophenols; Binding Sites; Chalcone; Colchicine; Cyclopropanes; Estradiol; Indans; Lignans; Models, Molecular; Molecular Structure; Nocodazole; Podophyllotoxin; Protein Binding; Stilbenes; Structure-Activity Relationship; Sulfonamides; Thiazoles; Tubulin; Tubulin Modulators	2005
Microwave-enhanced synthesis of new (-)-steganacin and (-)-steganone aza analogues. Organic letters, 2006, Feb-02, Volume: 8, Issue:3 Topics: 4-Butyrolactone; Aza Compounds; Cyclization; Lignans; Microwaves; Molecular Structure; Stereoisomerism; Triazoles	2006
Replacement of the lactone moiety on podophyllotoxin and steganacin analogues with a 1,5-disubstituted 1,2,3-triazole via ruthenium-catalyzed click chemistry. Bioorganic & medicinal chemistry, 2007, Nov-01, Volume: 15, Issue:21 Topics: 4-Butyrolactone; Antineoplastic Agents; Catalysis; Cell Line, Tumor; Humans; Lactones; Lignans; Molecular Conformation; Podophyllotoxin; Ruthenium; Triazoles; Tubulin	2007
Diversity oriented microwave-assisted synthesis of (-)-steganacin aza-analogues. The Journal of organic chemistry, 2008, Oct-03, Volume: 73, Issue:19 Topics: 4-Butyrolactone; Antineoplastic Agents; Aza Compounds; Lactones; Lignans; Microwaves; Tubulin Modulators	2008