Compounds > staurosporine
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staurosporine and valproic acid

staurosporine has been researched along with valproic acid in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baras, A; Chua, A; Maxhimer, JB; Nguyen, DM; Schrump, DS; Shamimi-Noori, S; Yeow, WS; Ziauddin, MF1
Anderson, E; Brown, R; Forster, S; Gibson, GG; Lyon, J; Plant, KE; Plant, N; Simecek, N; Spinks, J; Toms, N1
Amstutz, RA; Hecker, RM; Niggli, FK; Schäfer, BW; Wachtel, M; Walter, D1
Boku, S; Inoue, T; Kato, A; Kitaichi, Y; Koyama, T; Nakagawa, S; Omiya, Y; Song, N; Takamura, N; Toda, H1
Das, G; Jagtap, JC; Mruthyunjaya, S; Pujari, R; Shah, RD; Shastry, P; Shelke, GV1

Other Studies

5 other study(ies) available for staurosporine and valproic acid

ArticleYear
Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01.
    British journal of cancer, 2006, May-22, Volume: 94, Issue:10

    Topics: Anticonvulsants; Antineoplastic Agents; Apoptosis; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Neoplasms; NF-kappa B; Staurosporine; Tumor Cells, Cultured; Valproic Acid

2006
The neuroprotective action of the mood stabilizing drugs lithium chloride and sodium valproate is mediated through the up-regulation of the homeodomain protein Six1.
    Toxicology and applied pharmacology, 2009, Feb-15, Volume: 235, Issue:1

    Topics: Antimanic Agents; Apoptosis; Cell Line, Tumor; Gene Expression Profiling; Gene Silencing; Homeodomain Proteins; Humans; Lithium Chloride; Neuroblastoma; Staurosporine; Up-Regulation; Valproic Acid

2009
p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment.
    Oncogene, 2010, Jul-08, Volume: 29, Issue:27

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Drug Synergism; Early Growth Response Protein 1; Female; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Genotype; Histone Deacetylase Inhibitors; Humans; Mice; Neoplasms; Paired Box Transcription Factors; Rhabdomyosarcoma, Alveolar; Staurosporine; Transcriptional Activation; Valproic Acid; Xenograft Model Antitumor Assays

2010
Mood stabilizers commonly restore staurosporine-induced increase of p53 expression and following decrease of Bcl-2 expression in SH-SY5Y cells.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Aug-07, Volume: 38, Issue:2

    Topics: Antimanic Agents; Apoptosis; Carbamazepine; Cell Line, Tumor; Enzyme Inhibitors; Gene Expression; Humans; Lamotrigine; Lithium; Neurons; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Triazines; Tumor Suppressor Protein p53; Valproic Acid

2012
Sodium valproate potentiates staurosporine-induced apoptosis in neuroblastoma cells via Akt/survivin independently of HDAC inhibition.
    Journal of cellular biochemistry, 2013, Volume: 114, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Benzamides; Caspase 3; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Activation; G2 Phase Cell Cycle Checkpoints; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Humans; Inhibitor of Apoptosis Proteins; Isoenzymes; Neuroblastoma; Proteolysis; Proto-Oncogene Proteins c-akt; Pyridines; Staurosporine; Survivin; Valproic Acid

2013