Page last updated: 2024-08-23

staurosporine and trichostatin a

staurosporine has been researched along with trichostatin a in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's5 (50.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Goekjian, P; Jochum, A; Jung, M; Kunick, C; Marshall, B; Meier, R; Saunders, L; Sippl, W; Trapp, J; Verdin, E1
Bolognini, D; Cattaneo, E; Kazantsev, AG; Mutti, C; Rigamonti, D; Sola, F; Tartari, M; Valenza, M; Zuccato, C1
Chen, SS; Lee, HY; Lee, S; Liu, YT; Tai, HC; Tuan, YL; Wang, HH; Wang, SW; Yen, JY; Yu, CL1
Appleton, S; Edmonds, B; James, R; Medina, V; Young, GP; Zalewski, PD1
Boone, E; De Bosscher, K; Haegeman, G; Plaisance, S; Vanden Berghe, W1
Bell, CW; Jiang, W; Pisetsky, DS; Reich, CF1
Chomienne, C; Gaymes, TJ; Mufti, GJ; Omidvar, N; Orr, S; Padua, RA; Pla, M; Rassool, FV1
Levin, LA; Millet, LE; Schwechter, BR1
Casson, RJ; Chidlow, G; Crowston, JG; Tran, T; Wood, JP1
Huang, D; Ji, Z; Liu, C; Su, J; Wang, H; Zhou, X1

Other Studies

10 other study(ies) available for staurosporine and trichostatin a

ArticleYear
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition.
    Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25

    Topics: Acetylation; Adenosine; Binding Sites; Cell Line, Tumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Mimicry; Protein Kinase Inhibitors; Sirtuins; Structure-Activity Relationship; Tubulin

2006
Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators.
    The Journal of biological chemistry, 2007, Aug-24, Volume: 282, Issue:34

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Gene Silencing; Huntingtin Protein; Immunohistochemistry; Luciferases; Models, Chemical; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Peptides; Rats; Transcription Factors

2007
Effect of phenylurea hydroxamic acids on histone deacetylase and VEGFR-2.
    Bioorganic & medicinal chemistry, 2021, 11-15, Volume: 50

    Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Molecular Structure; Phenylurea Compounds; Protein Kinase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured; Vascular Endothelial Growth Factor Receptor-2

2021
Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway.
    Cancer research, 1997, Sep-01, Volume: 57, Issue:17

    Topics: Apoptosis; bcl-2-Associated X Protein; Butyrates; Butyric Acid; Caspase 3; Caspases; Cells, Cultured; Cycloheximide; Cysteine Endopeptidases; Cytochrome c Group; DNA Fragmentation; DNA, Neoplasm; Enzyme Induction; Histone Deacetylases; Humans; Hydroxamic Acids; Jurkat Cells; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine

1997
The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.
    The Journal of biological chemistry, 1999, Nov-05, Volume: 274, Issue:45

    Topics: Acetyltransferases; Animals; Cells, Cultured; E1A-Associated p300 Protein; Histone Acetyltransferases; Humans; Hydroxamic Acids; Interleukin-6; Mice; NF-kappa B; Nuclear Proteins; Promoter Regions, Genetic; Saccharomyces cerevisiae Proteins; Staurosporine; Trans-Activators; Transcriptional Activation; Tumor Necrosis Factor-alpha

1999
The extracellular release of HMGB1 during apoptotic cell death.
    American journal of physiology. Cell physiology, 2006, Volume: 291, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Etoposide; HMGB1 Protein; Humans; Hydroxamic Acids; Protein Synthesis Inhibitors; Staurosporine; Tumor Necrosis Factor-alpha

2006
Histone deacetylase inhibitors (HDI) cause DNA damage in leukemia cells: a mechanism for leukemia-specific HDI-dependent apoptosis?
    Molecular cancer research : MCR, 2006, Volume: 4, Issue:8

    Topics: Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Butyrates; Cell Cycle Proteins; Chromatin Assembly and Disassembly; DNA Damage; DNA-Binding Proteins; Gamma Rays; Histone Deacetylase Inhibitors; Histones; HL-60 Cells; Humans; Hydroxamic Acids; K562 Cells; Mice; Mice, Transgenic; Organ Specificity; Peptides, Cyclic; Phosphorylation; Protein Serine-Threonine Kinases; RNA Interference; Staurosporine; Transfection; Tumor Suppressor Proteins

2006
Histone deacetylase inhibition-mediated differentiation of RGC-5 cells and interaction with survival.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:6

    Topics: Acetylation; Animals; Antibodies, Monoclonal; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Microtubule-Associated Proteins; Nerve Growth Factors; Neurites; Rats; Retinal Ganglion Cells; Staurosporine

2007
A comparison of differentiation protocols for RGC-5 cells.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:7

    Topics: Animals; Biomarkers; Cell Differentiation; Cell Line; Cell Lineage; Concanavalin A; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Hydroxamic Acids; Intermediate Filament Proteins; Mice; Nerve Tissue Proteins; Nestin; Opsins; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine

2010
Integrating genomics and proteomics data to predict drug effects using binary linear programming.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Antineoplastic Agents; Benzamides; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Digoxigenin; Female; Gene Expression; Gene Regulatory Networks; Genomics; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Hydroxamic Acids; MCF-7 Cells; Phosphorylation; Programming, Linear; Proteome; Proteomics; Pyridines; Signal Transduction; Staurosporine; Tumor Suppressor Protein p53

2014