Compounds > staurosporine
Page last updated: 2024-08-23

staurosporine and triazoles

staurosporine has been researched along with triazoles in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (27.78)18.2507
2000's4 (22.22)29.6817
2010's5 (27.78)24.3611
2020's4 (22.22)2.80

Authors

AuthorsStudies
Müller, S; Nigam, S1
Eskafi, S; Müller, S; Nigam, S; Zhang, H1
Barnes, PJ; Giembycz, MA; Kroegel, C; Matthys, H; Westwick, J1
Dohi, T; Kitayama, S; Morita, K; Okamoto, H; Shibata, K1
Bernasconi, S; Dejana, E; Del Maschio, A; Martín-Padura, I1
Davies, SP; Donella-Deana, A; Meggio, F; Pinna, LA; Reddy, H; Ruzzene, M; Sarno, S; Shugar, D1
Figg, WD; Krüger, EA1
Canas, PM; Cunha, RA; Oliveira, CR; Porciúncula, LO; Silva, CG1
Duncan, JS; Kerman, K; Kraatz, HB; Litchfield, DW; Song, H1
Bhatt, L; Chang, CJ; Cotter, TG; Dickinson, BC; Gough, DR; Naughton, R; Stanicka, J; Woolley, JF1
Beck, IM; Bougarne, N; Bracke, M; Chateauvieux, S; De Bosscher, K; Dejager, L; Diederich, M; Gaigneaux, A; Haegeman, G; Libert, C; Ratman, D; Tavernier, J; Vanden Berghe, W1
Jiang, JR; Pan, WG; Shou, QY; Wang, J; Wu, HG; Wu, JY; Xu, F; Yang, XL; Yang, ZZ; Zhu, Y1
Tollkuci, E1
Juric, DM; Lipnik-Stangelj, M; Simenc, J1
Cornely, OA; Koehler, P; Maurer, C; Müller, C; Stemler, J1
Al Kafri, N; Hafizi, S1
Abdul-Hamil, NA; Cherchione, C; Martinelli, G; Nagarajan, C; Wong, GC1
Del Principe, MI; Marchesi, F; Menna, P; Minotti, G; Pagano, L; Perrone, S; Salvatorelli, E1

Reviews

2 review(s) available for staurosporine and triazoles

ArticleYear
Antifungal prophylaxis and novel drugs in acute myeloid leukemia: the midostaurin and posaconazole dilemma.
    Annals of hematology, 2020, Volume: 99, Issue:7

    Topics: Antifungal Agents; Chemoprevention; Drug Interactions; Drugs, Investigational; Humans; Invasive Fungal Infections; Leukemia, Myeloid, Acute; Prognosis; Staurosporine; Triazoles

2020
Midostaurin in acute myeloid leukemia: current evidence and practical considerations in routine clinical use.
    Minerva medica, 2020, Volume: 111, Issue:5

    Topics: Aniline Compounds; Anthracyclines; Antifungal Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Echinocandins; fms-Like Tyrosine Kinase 3; Forecasting; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Mutation; Mycoses; Protein Kinase Inhibitors; Pyrazines; Randomized Controlled Trials as Topic; Recurrence; Staurosporine; Triazoles

2020

Other Studies

16 other study(ies) available for staurosporine and triazoles

ArticleYear
Enhancement by staurosporine of platelet-activating factor formation in N-formyl peptide-challenged human neutrophils is mediated by intracellular platelet-activating factor binding sites.
    Biochemical and biophysical research communications, 1992, Dec-15, Volume: 189, Issue:2

    Topics: Alkaloids; Azepines; Binding Sites; Calcium; Drug Synergism; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Triazoles

1992
Evidence for the predominant role of intracellular PAF binding sites in the regulation of phospholipase A2 in human neutrophils.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Alkaloids; Azepines; Humans; Indoles; Leukotriene Antagonists; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Triazoles

1995
Modulatory role of protein kinase C on the signal transduction pathway utilized by platelet-activating factor in eosinophil activation.
    American journal of respiratory cell and molecular biology, 1994, Volume: 11, Issue:5

    Topics: Alkaloids; Animals; Azepines; Calcium; Cell Membrane; Cytosol; Eosinophil Peroxidase; Eosinophils; Guinea Pigs; Male; Peritoneal Lavage; Peroxidases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Triazoles

1994
Ca2+ entry induced by calcium influx factor and its regulation by protein kinase C in rabbit neutrophils.
    Biochemical pharmacology, 1996, Jul-12, Volume: 52, Issue:1

    Topics: Adrenal Glands; Alkaloids; Animals; Azepines; Calcium; Calcium Channel Blockers; Cattle; Chromaffin Granules; Enzyme Inhibitors; Imidazoles; Ion Transport; Neutrophils; Platelet Activating Factor; Protein Kinase C; Rabbits; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Triazoles

1996
Triggering of beta 1-integrin chain induces platelet adhesion to cultured endothelium.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:11

    Topics: Alprostadil; Animals; Antibodies, Monoclonal; Aspirin; Azepines; Blood Platelets; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Extracellular Matrix Proteins; Humans; Integrin beta1; Mice; Mice, Inbred BALB C; Nitroprusside; P-Selectin; Platelet Adhesiveness; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Staurosporine; Thienopyridines; Triazoles

1997
Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').
    FEBS letters, 2001, May-04, Volume: 496, Issue:1

    Topics: Adenosine Triphosphate; Amino Acid Substitution; Binding Sites; Binding, Competitive; Casein Kinase II; Emodin; Enzyme Inhibitors; Humans; Jurkat Cells; Protein Kinases; Protein Serine-Threonine Kinases; Staurosporine; Substrate Specificity; Triazoles

2001
Protein binding alters the activity of suramin, carboxyamidotriazole, and UCN-01 in an ex vivo rat aortic ring angiogenesis assay.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:7

    Topics: Alkaloids; Angiogenesis Inhibitors; Animals; Aorta, Thoracic; Biological Assay; Blood Proteins; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Neovascularization, Pathologic; Protein Binding; Rats; Rats, Sprague-Dawley; Staurosporine; Suramin; Triazoles

2001
Blockade of adenosine A(2A) receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons.
    Neurobiology of disease, 2007, Volume: 27, Issue:2

    Topics: Adenosine A2 Receptor Antagonists; Animals; Apoptosis; Blotting, Western; Cells, Cultured; Enzyme Inhibitors; Hippocampus; Immunohistochemistry; Male; Mitochondria; Neurons; Phosphoprotein Phosphatases; Rats; Rats, Wistar; Staurosporine; Synaptophysin; Triazines; Triazoles

2007
Peptide biosensors for the electrochemical measurement of protein kinase activity.
    Analytical chemistry, 2008, Dec-15, Volume: 80, Issue:24

    Topics: Adenosine Triphosphate; Benzimidazoles; Biosensing Techniques; Bone Neoplasms; Casein Kinase II; Catalysis; Electrochemistry; Ferrous Compounds; fms-Like Tyrosine Kinase 3; Humans; Kinetics; Metallocenes; Mutation; Osteosarcoma; Oxidation-Reduction; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Receptor, ErbB-2; Staurosporine; Triazoles; Tumor Cells, Cultured

2008
H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Benzoxazoles; Cell Line, Tumor; Endoplasmic Reticulum; Fluorescent Dyes; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hydrogen Peroxide; Imidazoles; Leukemia, Myeloid, Acute; Mitochondria; Mutation; NADPH Oxidases; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-pim-1; Pyrroles; RNA, Small Interfering; Signal Transduction; STAT5 Transcription Factor; Staurosporine; Triazoles

2012
Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1.
    Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:1

    Topics: Animals; Cell Line, Tumor; Dexamethasone; Dual Specificity Phosphatase 1; Gene Expression; Humans; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Receptors, Glucocorticoid; RNA Interference; RNA, Small Interfering; Staurosporine; Transcription Factor AP-1; Transcriptional Activation; Triazoles; Tumor Necrosis Factor-alpha

2014
Synthesis, antitumor evaluation and molecular docking studies of [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine derivatives.
    Bioorganic & medicinal chemistry letters, 2016, 07-01, Volume: 26, Issue:13

    Topics: Animals; Antineoplastic Agents; Binding Sites; Drug Screening Assays, Antitumor; Heterocyclic Compounds, 2-Ring; HL-60 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Mice, Inbred ICR; Molecular Docking Simulation; Proto-Oncogene Proteins c-met; Staurosporine; Structure-Activity Relationship; Triazoles

2016
Isavuconazole therapy in an FLT3 mutated acute myeloid leukemia patient receiving midostaurin: A case report.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:4

    Topics: Adult; Antineoplastic Agents; Cytochrome P-450 CYP3A Inhibitors; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Mutation; Nitriles; Protein Kinase Inhibitors; Pyridines; Staurosporine; Triazoles

2019
NADPH oxidase inhibitor VAS2870 prevents staurosporine-induced cell death in rat astrocytes.
    Radiology and oncology, 2019, 01-19, Volume: 53, Issue:1

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Benzoxazoles; Caspase 3; Caspase 7; Cell Death; Cell Survival; Enzyme Induction; Flow Cytometry; Membrane Potential, Mitochondrial; NADPH Oxidases; Rats; Rats, Wistar; Reactive Oxygen Species; Staurosporine; Triazoles

2019
Galectin-3 Stimulates Tyro3 Receptor Tyrosine Kinase and Erk Signalling, Cell Survival and Migration in Human Cancer Cells.
    Biomolecules, 2020, 07-11, Volume: 10, Issue:7

    Topics: Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Blood Proteins; Cell Line, Tumor; Cell Movement; Cell Survival; Galectin 3; Galectins; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Neoplasms; Phosphorylation; Protein S; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Staurosporine; Triazoles

2020
Choosing Antifungals for the Midostaurin-Treated Patient: Does CYP3A4 Outweigh Recommendations? A Brief Insight from Real Life.
    Chemotherapy, 2021, Volume: 66, Issue:1-2

    Topics: Adult; Aged; Antifungal Agents; Antineoplastic Agents; Cytochrome P-450 CYP3A; Diarrhea; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Mycoses; Staurosporine; Triazoles

2021