Compounds > staurosporine
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staurosporine and transforming growth factor beta

staurosporine has been researched along with transforming growth factor beta in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's29 (51.79)18.2507
2000's21 (37.50)29.6817
2010's5 (8.93)24.3611
2020's1 (1.79)2.80

Authors

AuthorsStudies
Koyama, N; Morisaki, N; Saito, Y; Yoshida, S1
Ikeda, K; Kikuchi, T; Matsumoto, T; Morimoto, K; Nakano, T; Ogata, E; Okazaki, R; Sakamoto, A; Urakawa, K1
Jeoung, DI; Sonenberg, M; Tang, B1
Clemmons, DR; McCusker, RH1
Gopalakrishna, R; Hinton, DR; Ogden, TE; Osusky, R; Ryan, SJ; Sakamoto, T; Sheu, SJ; Wang, HM1
Chang, NS4
Chen, Y; Hanazawa, S; Kitano, S; Takeshita, A; Watanabe, A1
Bereta, J; Bereta, M; Cohen, MC; Cohen, S1
Halstead, J; Ignotz, RA; Kemp, K1
Fukami, J; Ide, T; Tsuji, K; Ueno, A1
Evans, CH; Georgescu, HI; Stadler, J; Stefanovic-Racic, M1
Bowen, W; Michalopoulos, GK; Petersen, B; Yee, CJ; Zarnegar, R1
Bégeot, M; Langlois, D; Ouali, R; Penhoat, A; Saez, JM; Viard, I1
Jones, KT; Sharpe, GR1
Gañan, Y; Hurlé, JM; Macias, D1
Horio, T; Ikeda, M; Johchi, M; Kohno, M; Kurihara, N; Takeda, T; Yasunari, K1
Gañan, Y; Garcia-Martinez, V; Hurle, JM; Macias, D1
Blum, WF; Ilvesmäki, V; Voutilainen, R1
Greenwel, P; Hu, W; Kohanski, RA; Ramirez, F1
Allard, P; Atfi, A; Chapdelaine, A; Chevalier, S; Lepage, K1
Cain, K; Cohen, GM; Couet, C; Inayat-Hussain, SH1
Martin, P; Suzuki, K; Yamada, H1
Henrich-Noack, P; Krieglstein, J; Prehn, JH1
Hampton, T; Li, J; Morgan, JP; Simons, M1
Abrams, WR; Bashir, MM; Kucich, U; Rosenbloom, J; Rosenbloom, JC1
Baylink, DJ; Mohan, S; Sampath, K; Srinivasan, N1
Arsura, M; Fausto, N; FitzGerald, MJ; Sonenshein, GE1
Barro, C; Berthier, S; Gaudin, P; Morel, F; Trocmé, C; Zaoui, P1
Basdra, EK; Kletsas, D; Papavassiliou, AG1
Danielpour, D; Hajouj, T; Hsing, AY; Kerner, H; Larisch-Bloch, S; Lechleider, RJ; Lotan, R; Roberts, AB; Roche, NS1
Boyan, BD; Dean, DD; Schwartz, Z; Sylvia, VL1
Chodon, T; Funayama, E; Furukawa, H; Igawa, HH; Sugihara, T1
Ahlemeyer, B; Bauerbach, E; Krieglstein, J; Zhu, Y1
Ma, ZJ; Yamaguchi, M1
Igarashi, A; Yamaguchi, M1
Chang, YC; Hsieh, YS; Lai, CC; Liu, JY; Yang, SF1
Flores-Jasso, CF; García-Sáinz, JA; Romero-Avila, MT1
Dai, C; Liu, Y; Yang, J1
Fiebeler, A; Güler, F; Haller, H; Leitges, M; Lindschau, C; Luft, FC; Menne, J; Quass, P1
Culmsee, C; Klumpp, S; Krieglstein, J; Zhu, Y1
Choi, KC; Hong, SH; Ju, EM; Kim, BC; Kim, IH; Kim, SJ; Lee, CH; Park, SH1
Keski-Oja, J; Solovyan, VT2
Huang, H; Li, J; Li, X; Li, Y; Liang, Y; Liu, S; Wang, H; Wang, L1
Canaff, L; Chihara, K; Hendy, GN; Kaji, H; Naito, J; Sowa, H; Sugimoto, T; Tobimatsu, T1
Keane, J; Kelly, DM; O'Leary, SM; O'Sullivan, MP; ten Bokum, AM1
Brunelli, S; Bruni, P; Cencetti, F; Clementi, E; Cossu, G; De Palma, C; Donati, C; Rapizzi, E1
Drabkin, HA; Gadgil, S; Hermanova, I; Kornblau, SM; Qiu, YH; Starkova, J; Zhang, N1
Alcorn, JF; Anathy, V; Dienz, O; Godburn, KE; Guala, AS; Janssen-Heininger, YM; Pociask, DA; Reiss, JN; Riches, DW; Roberson, EC; Tully, JE1
Chen, X; Fan, Y; Guo, N; Han, J; Yang, B; Zhang, L1
Baselga, J; Bennett, KL; Colinge, J; Ibrahim, Y; Kerzendorfer, C; Klepsch, F; Kubicek, S; Lechtermann, H; Leitner, E; Macho-Maschler, S; Mair, B; Muellner, MK; Müller, AC; Nijman, SM; Rix, U; Serra, V; Superti-Furga, G; Trefzer, C1
Kei, K; Kim, H; Sonn, JK1
Chen, Y; Liu, N; Qi, D; Tong, X; Wen, J; Ye, X1

Other Studies

56 other study(ies) available for staurosporine and transforming growth factor beta

ArticleYear
Regulatory effects of platelet-derived growth factor-AA homodimer on migration of vascular smooth muscle cells.
    The Journal of biological chemistry, 1992, Nov-15, Volume: 267, Issue:32

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Aorta, Thoracic; Biological Factors; Bucladesine; Cell Division; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Fibronectins; Isoquinolines; Kinetics; Macromolecular Substances; Muscle, Smooth, Vascular; Pertussis Toxin; Piperazines; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Wistar; Recombinant Proteins; Second Messenger Systems; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Virulence Factors, Bordetella

1992
Transcriptional activation of c-fos and c-jun protooncogenes by serum growth factors in osteoblast-like MC3T3-E1 cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Cell Differentiation; Cycloheximide; Dactinomycin; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression Regulation; Growth Substances; Insulin-Like Growth Factor I; Isoquinolines; Mice; Osteoblasts; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA, Messenger; Staurosporine; Transforming Growth Factor beta

1992
Mitogenic response to TGF-beta in 3T3-F442A cells.
    Biochemical and biophysical research communications, 1995, Nov-22, Volume: 216, Issue:3

    Topics: 3T3 Cells; Alkaloids; Animals; Cell Division; Cyclin D1; Cyclins; Dose-Response Relationship, Drug; Growth Hormone; Kinetics; Mice; Oncogene Proteins; Protein Kinase C; Staurosporine; Transforming Growth Factor beta

1995
Effects of cytokines on insulin-like growth factor-binding protein secretion by muscle cells in vitro.
    Endocrinology, 1994, Volume: 134, Issue:5

    Topics: Alkaloids; Animals; Blotting, Western; Carrier Proteins; Cell Line; Culture Media, Conditioned; Cytokines; Epidermal Growth Factor; Fibroblast Growth Factor 2; Insulin; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Mice; Muscle, Smooth, Vascular; Muscles; Rats; Staurosporine; Suramin; Swine; Thrombin; Transforming Growth Factor beta

1994
Transforming growth factor-beta regulates human retinal pigment epithelial cell phagocytosis by influencing a protein kinase C-dependent pathway.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1994, Volume: 232, Issue:11

    Topics: Alkaloids; Animals; Cattle; Cells, Cultured; Flow Cytometry; Humans; Naphthalenes; Phagocytosis; Pigment Epithelium of Eye; Polycyclic Compounds; Protein Kinase C; Rod Cell Outer Segment; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Up-Regulation

1994
Transforming growth factor-beta 1 induction of novel extracellular matrix proteins that trigger resistance to tumor necrosis factor cytotoxicity in murine L929 fibroblasts.
    The Journal of biological chemistry, 1995, Mar-31, Volume: 270, Issue:13

    Topics: Alkaloids; Animals; Catechols; Cell Survival; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Fibroblasts; Genistein; Isoflavones; Kinetics; L Cells; Mice; Nitriles; Phenols; Phosphotyrosine; Protein Kinase Inhibitors; Staurosporine; Transforming Growth Factor beta; Tumor Protein, Translationally-Controlled 1; Tyrosine; Tyrphostins

1995
TGF-beta induces expression of monocyte chemoattractant JE/monocyte chemoattractant protein 1 via transcriptional factor AP-1 induced by protein kinase in osteoblastic cells.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Jul-01, Volume: 155, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Base Sequence; Chemokine CCL2; Chemotactic Factors; Cytokines; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation; Genes, fos; Genes, jun; Humans; Isoquinolines; Mice; Molecular Sequence Data; Oligonucleotides, Antisense; Osteoblasts; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Staurosporine; Transcription Factor AP-1; Transcription, Genetic; Transforming Growth Factor beta

1995
Regulation of VCAM-1 expression and involvement in cell adhesion to murine microvascular endothelium.
    Cellular immunology, 1993, Apr-01, Volume: 147, Issue:2

    Topics: Alkaloids; Animals; Cell Adhesion; Cell Adhesion Molecules; Cytokines; Endothelium, Vascular; Fibronectins; Gene Expression; Humans; In Vitro Techniques; Mice; Mice, Inbred DBA; Receptors, Leukocyte-Adhesion; RNA, Messenger; Rosette Formation; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta; Vascular Cell Adhesion Molecule-1

1993
Evidence for involvement of phosphatidylcholine-phospholipase C and protein kinase C in transforming growth factor-beta signaling.
    The Journal of biological chemistry, 1995, Jun-09, Volume: 270, Issue:23

    Topics: Alkaloids; Bridged-Ring Compounds; GTP-Binding Proteins; Humans; Norbornanes; Phosphatidylcholines; Plasminogen Activator Inhibitor 1; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Transforming Growth Factor beta; Tumor Cells, Cultured; Type C Phospholipases

1995
Transforming growth factor-beta 1 has both promoting and inhibiting effects on induction of DNA synthesis in human fibroblasts.
    Experimental cell research, 1995, Volume: 216, Issue:1

    Topics: Alkaloids; DNA; DNA-Binding Proteins; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; GTP-Binding Proteins; Humans; Pertussis Toxin; Protein Kinase C; Resting Phase, Cell Cycle; Signal Transduction; Staurosporine; Transforming Growth Factor beta; Virulence Factors, Bordetella

1995
Nitric oxide synthesis and its regulation by rabbit synoviocytes.
    The Journal of rheumatology, 1994, Volume: 21, Issue:10

    Topics: Alkaloids; Animals; Cell Line; Cells, Cultured; Cytokines; Dinoprostone; Fibroblasts; Free Radicals; Interferon-gamma; Interleukin-1; Metalloendopeptidases; Nitric Oxide; Platelet-Derived Growth Factor; Protein Kinase C; Rabbits; Staurosporine; Synovial Membrane; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

1994
Distinct morphological and mito-inhibitory effects induced by TGF-beta 1, HGF and EGF on mouse, rat and human hepatocytes.
    Cell biology and toxicology, 1994, Volume: 10, Issue:4

    Topics: Alkaloids; Animals; Cell Size; Cells, Cultured; Cycloheximide; Cytoskeletal Proteins; Cytoskeleton; DNA Replication; Dose-Response Relationship, Drug; Epidermal Growth Factor; Female; Genistein; Hepatocyte Growth Factor; Humans; Isoflavones; Liver; Male; Mice; Rats; Rats, Inbred F344; Staurosporine; Sulfonamides; Transforming Growth Factor beta

1994
Peptide hormone and growth factor regulation of nuclear proto-oncogenes and specific functions in adrenal cells.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 50, Issue:5-6

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Alkaloids; Angiotensin II; Animals; Calcium; Cattle; Gene Expression Regulation; Genes, fos; Genes, jun; Growth Substances; In Vitro Techniques; Insulin-Like Growth Factor I; Staurosporine; Transforming Growth Factor beta; Trifluoperazine

1994
Proliferating cell nuclear antigen decreases in normal human keratinocytes with differentiation stimuli but not in an HPV immortalised cell line.
    Acta dermato-venereologica, 1994, Volume: 74, Issue:4

    Topics: Alkaloids; Calcitriol; Cell Line, Transformed; Fluorescent Antibody Technique; Humans; Keratinocytes; Papillomaviridae; Phorbol Esters; Proliferating Cell Nuclear Antigen; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta

1994
Modification of the phalangeal pattern of the digits in the chick embryo leg bud by local microinjection of RA, staurosporin and TGF beta's.
    Anatomy and embryology, 1993, Volume: 188, Issue:2

    Topics: Alkaloids; Animals; Chick Embryo; Hindlimb; Microscopy, Electron, Scanning; Staurosporine; Toes; Transforming Growth Factor beta; Tretinoin

1993
Interaction of PDGF and natriuretic peptides on mesangial cell proliferation and endothelin secretion.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Atrial Natriuretic Factor; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Endothelins; Glomerular Mesangium; Isoquinolines; Kinetics; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Nitroprusside; Piperazines; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Thymidine; Transforming Growth Factor beta

1993
In vivo experimental induction of interdigital tissue chondrogenesis in the avian limb bud results in the formation of extradigits. Effects of local microinjection of staurosporine, zinc chloride and growth factors.
    Progress in clinical and biological research, 1993, Volume: 383A

    Topics: Alkaloids; Animals; Cartilage; Chick Embryo; Chlorides; Epidermal Growth Factor; Hindlimb; Mesoderm; Microinjections; Protein Kinase C; Staurosporine; Toes; Transforming Growth Factor beta; Zinc Compounds

1993
Insulin-like growth factor-II in human fetal adrenals: regulation by ACTH, protein kinase C and growth factors.
    The Journal of endocrinology, 1993, Volume: 137, Issue:3

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Alkaloids; Blotting, Northern; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Gene Expression; Gene Expression Regulation; Genes; Growth Substances; Humans; Insulin-Like Growth Factor II; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta

1993
Tyrosine dephosphorylation of nuclear proteins mimics transforming growth factor beta 1 stimulation of alpha 2(I) collagen gene expression.
    Molecular and cellular biology, 1995, Volume: 15, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Collagen; Enzyme Inhibitors; Ethers, Cyclic; Fetus; Fibroblasts; Gene Expression; Genistein; Humans; Isoflavones; Isoquinolines; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphotyrosine; Piperazines; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Skin; Staurosporine; Transcription, Genetic; Transforming Growth Factor beta; Vanadates

1995
Activation of a serine/threonine kinase signaling pathway by transforming growth factor type beta.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Dec-19, Volume: 92, Issue:26

    Topics: 3T3 Cells; Alkaloids; Animals; Cell Line; CHO Cells; Cricetinae; DNA; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Mice; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Receptor Protein-Tyrosine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Signal Transduction; Staurosporine; Swine; Thymidine; Transforming Growth Factor beta; Tumor Cells, Cultured

1995
A cleavage-site-directed inhibitor of interleukin-1 beta-converting enzyme-like proteases inhibits apoptosis in primary cultures of rat hepatocytes.
    The Biochemical journal, 1996, Feb-15, Volume: 314 ( Pt 1)

    Topics: Alkaloids; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 1; Cell Nucleus; Cells, Cultured; Chromatin; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA; Electrophoresis, Agar Gel; Liver; Male; Nucleosomes; Oligopeptides; Protease Inhibitors; Rats; Staurosporine; Transforming Growth Factor beta

1996
Impairment of protein kinase C activity in twitcher Schwann cells in vitro.
    Brain research, 1996, Apr-29, Volume: 718, Issue:1-2

    Topics: Animals; Cattle; Cell Division; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Fibroblast Growth Factor 2; Glia Maturation Factor; Growth Inhibitors; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Pituitary Gland; Platelet-Derived Growth Factor; Protein Kinase C; Recombinant Proteins; Schwann Cells; Staurosporine; Tissue Extracts; Transforming Growth Factor beta

1996
TGF-beta 1 protects hippocampal neurons against degeneration caused by transient global ischemia. Dose-response relationship and potential neuroprotective mechanisms.
    Stroke, 1996, Volume: 27, Issue:9

    Topics: Animals; Apoptosis; Cell Death; Dose-Response Relationship, Drug; Hippocampus; Injections; Injections, Intraventricular; Ischemic Attack, Transient; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitric Oxide; Oxidation-Reduction; Pyramidal Cells; Rats; Rats, Wistar; Staurosporine; Time Factors; Transforming Growth Factor beta

1996
Stretch-induced VEGF expression in the heart.
    The Journal of clinical investigation, 1997, Jul-01, Volume: 100, Issue:1

    Topics: Angiotensin II; Animals; Antibodies; Catheterization; Diastole; Endothelial Growth Factors; Endothelin Receptor Antagonists; Endothelin-1; Heart; In Vitro Techniques; Lymphokines; Male; Myocardial Ischemia; Myocardium; Peptides, Cyclic; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Saralasin; Staurosporine; Transcription, Genetic; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1997
Stabilization of elastin mRNA by TGF-beta: initial characterization of signaling pathway.
    American journal of respiratory cell and molecular biology, 1997, Volume: 17, Issue:1

    Topics: Bridged-Ring Compounds; Cell Line; Cell Nucleus; Elastin; Enzyme Inhibitors; Fetus; Fibroblasts; Humans; Kinetics; Lung; Naphthalenes; Norbornanes; RNA, Messenger; Signal Transduction; Staurosporine; Thiocarbamates; Thiones; Transcription, Genetic; Transforming Growth Factor beta; Type C Phospholipases

1997
Effects of inhibitors of signal transduction pathways on transforming growth factor beta1 and osteogenic protein-1-induced insulinlike growth factor binding protein-3 expression in human bone cells.
    Journal of cellular physiology, 1997, Volume: 173, Issue:1

    Topics: Bone and Bones; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Cells, Cultured; Culture Media, Conditioned; Gene Expression Regulation; Genistein; Humans; Insulin-Like Growth Factor Binding Protein 3; Isoflavones; Okadaic Acid; Osteoblasts; Phosphoprotein Phosphatases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Cells, Cultured; Vanadates

1997
Nuclear factor-kappaB/Rel blocks transforming growth factor beta1-induced apoptosis of murine hepatocyte cell lines.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1997, Volume: 8, Issue:10

    Topics: Animals; Apoptosis; Cell Line; DNA-Binding Proteins; Down-Regulation; Immunoblotting; Liver; Mice; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; Signal Transduction; Staurosporine; Time Factors; Transcription Factor RelB; Transcription Factors; Transfection; Transforming Growth Factor beta

1997
Human B lymphocytes synthesize the 92-kDa gelatinase, matrix metalloproteinase-9.
    The Journal of biological chemistry, 1998, Aug-07, Volume: 273, Issue:32

    Topics: Androstadienes; B-Lymphocytes; Captopril; Cell Movement; Collagenases; Concanavalin A; Cytokines; Gene Expression Regulation, Enzymologic; Growth Substances; Herpesvirus 4, Human; Humans; Lipopolysaccharides; Matrix Metalloproteinase 9; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Transformation, Genetic; Transforming Growth Factor beta; Wortmannin

1998
Mechanical stress induces DNA synthesis in PDL fibroblasts by a mechanism unrelated to autocrine growth factor action.
    FEBS letters, 1998, Jul-03, Volume: 430, Issue:3

    Topics: Culture Media, Conditioned; DNA; Enzyme Inhibitors; Fibroblasts; Humans; Mitogens; Periodontal Ligament; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Staurosporine; Stress, Mechanical; Transforming Growth Factor beta

1998
Selective loss of the transforming growth factor-beta apoptotic signaling pathway in mutant NRP-154 rat prostatic epithelial cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 2000, Volume: 11, Issue:1

    Topics: Animals; Apoptosis; bcl-X Protein; Cell Division; In Situ Nick-End Labeling; Male; Mutagenesis, Insertional; Okadaic Acid; Prostate; Proto-Oncogene Proteins c-bcl-2; Rats; Receptors, Transforming Growth Factor beta; Retroviridae; RNA, Messenger; Signal Transduction; Staurosporine; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured

2000
Transforming growth factor-beta1 regulation of resting zone chondrocytes is mediated by two separate but interacting pathways.
    Biochimica et biophysica acta, 2000, Apr-17, Volume: 1496, Issue:2-3

    Topics: Alkaline Phosphatase; Alkaloids; Animals; Arachidonic Acid; Benzophenanthridines; Cell Division; Cell Membrane; Chondrocytes; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Male; Phenanthridines; Phospholipases A; Protein Kinase C; Proteoglycans; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Transforming Growth Factor beta

2000
Keloid-derived fibroblasts are refractory to Fas-mediated apoptosis and neutralization of autocrine transforming growth factor-beta1 can abrogate this resistance.
    The American journal of pathology, 2000, Volume: 157, Issue:5

    Topics: Antibodies; Apoptosis; Autocrine Communication; bcl-2-Associated X Protein; bcl-X Protein; Caspases; Cells, Cultured; Drug Resistance; Enzyme Activation; fas Receptor; Fibroblasts; Humans; Keloid; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Transforming Growth Factor beta; Transforming Growth Factor beta1

2000
TGF-beta1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal cultures.
    Neurochemistry international, 2001, Volume: 38, Issue:3

    Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fluorometry; Hippocampus; In Situ Nick-End Labeling; Neurons; Rats; Rats, Inbred F344; Staurosporine; Transforming Growth Factor beta; Transforming Growth Factor beta1

2001
Hyaluronidase activation of c-Jun N-terminal kinase is necessary for protection of L929 fibrosarcoma cells from staurosporine-mediated cell death.
    Biochemical and biophysical research communications, 2001, May-04, Volume: 283, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line; COS Cells; Drug Resistance; Enzyme Activation; Humans; Hyaluronoglucosaminidase; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mitogen-Activated Protein Kinases; Staurosporine; Transforming Growth Factor beta; Tumor Cells, Cultured

2001
Stimulatory effect of zinc on deoxyribonucleic acid synthesis in bone growth of newborn rats: enhancement with zinc and insulin-like growth factor-I.
    Calcified tissue international, 2001, Volume: 69, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Bone Development; Cells, Cultured; Diaphyses; DNA; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Female; Femur; Flavonoids; Insulin-Like Growth Factor I; Male; Mitogen-Activated Protein Kinases; Nucleic Acid Synthesis Inhibitors; Picolinic Acids; Rats; Rats, Wistar; Staurosporine; Transforming Growth Factor beta; Zinc Sulfate

2001
The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression.
    The Journal of biological chemistry, 2002, Mar-22, Volume: 277, Issue:12

    Topics: Animals; Ankyrins; Apoptosis; Cell Division; Cell Line; Cell Nucleus; COS Cells; Cytosol; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Etoposide; Genes, Dominant; Humans; Hyaluronoglucosaminidase; Hypoxia; I-kappa B Proteins; Liver; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; NF-KappaB Inhibitor alpha; Phosphorylation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serine; Spleen; Staurosporine; Threonine; Time Factors; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays

2002
Characterization of the increase in bone 66 kDa protein component with healing rat fractures: stimulatory effect of zinc.
    International journal of molecular medicine, 2002, Volume: 9, Issue:5

    Topics: Animals; Bone and Bones; Cycloheximide; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Estradiol; Flavonoids; Fracture Healing; Fractures, Bone; Insulin-Like Growth Factor I; Male; Parathyroid Hormone; Phosphoproteins; Rats; Rats, Wistar; Staurosporine; Time Factors; Transforming Growth Factor beta; Zinc

2002
Transforming growth factor-beta1 blocks the enhancement of tumor necrosis factor cytotoxicity by hyaluronidase Hyal-2 in L929 fibroblasts.
    BMC cell biology, 2002, Apr-03, Volume: 3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Cell Adhesion Molecules; Cell Division; Cell Line; COS Cells; Fibroblasts; GPI-Linked Proteins; Hyaluronoglucosaminidase; Mice; Mitochondria; Molecular Sequence Data; NF-kappa B; Oxidoreductases; Protein Transport; Staurosporine; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; WW Domain-Containing Oxidoreductase

2002
Regulation of matrix metalloproteinase production by cytokines, pharmacological agents and periodontal pathogens in human periodontal ligament fibroblast cultures.
    Journal of periodontal research, 2002, Volume: 37, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aggregatibacter actinomycetemcomitans; Cells, Cultured; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Interleukin-1; Matrix Metalloproteinase 2; Periodontal Diseases; Periodontal Ligament; Porphyromonas gingivalis; Protein Kinase C; Protein Synthesis Inhibitors; Staurosporine; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta

2002
alpha1B-Adrenergic receptor phosphorylation and desensitization induced by transforming growth factor-beta.
    The Biochemical journal, 2002, Dec-01, Volume: 368, Issue:Pt 2

    Topics: Androstadienes; Animals; Calcium; Cells, Cultured; Chromones; COS Cells; Enzyme Inhibitors; Indoles; Inositol Phosphates; Maleimides; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Receptors, Transforming Growth Factor beta; Staurosporine; Transforming Growth Factor beta; Wortmannin

2002
Transforming growth factor-beta1 potentiates renal tubular epithelial cell death by a mechanism independent of Smad signaling.
    The Journal of biological chemistry, 2003, Apr-04, Volume: 278, Issue:14

    Topics: Caspase 3; Caspase 9; Caspases; Cell Death; Cells, Cultured; DNA-Binding Proteins; Enzyme Inhibitors; Enzyme Precursors; Epithelial Cells; Humans; Kidney Tubules, Proximal; Mitogen-Activated Protein Kinases; Oxazoles; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction; Smad2 Protein; Smad7 Protein; Staurosporine; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1

2003
Glucose-induced TGF-beta1 and TGF-beta receptor-1 expression in vascular smooth muscle cells is mediated by protein kinase C-alpha.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:3

    Topics: Activin Receptors, Type I; Animals; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression Regulation; Glucose; Green Fluorescent Proteins; Luminescent Proteins; Microscopy, Confocal; Muscle, Smooth, Vascular; Naphthalenes; Oligonucleotides, Antisense; Protein Kinase C; Protein Kinase C-alpha; Protein Serine-Threonine Kinases; Rats; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Staurosporine; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1

2003
Neuroprotection by transforming growth factor-beta1 involves activation of nuclear factor-kappaB through phosphatidylinositol-3-OH kinase/Akt and mitogen-activated protein kinase-extracellular-signal regulated kinase1,2 signaling pathways.
    Neuroscience, 2004, Volume: 123, Issue:4

    Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcium-Binding Proteins; Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Hippocampus; Immunohistochemistry; MAP Kinase Signaling System; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred F344; Staurosporine; Synaptotagmin I; Synaptotagmins; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2004
Apoptosis of mink lung epithelial cells by co-treatment of low-dose staurosporine and transforming growth factor-beta1 depends on the enhanced TGF-beta signaling and requires the decreased phosphorylation of PKB/Akt.
    Biochemical and biophysical research communications, 2005, Mar-25, Volume: 328, Issue:4

    Topics: Animals; Apoptosis; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Combinations; Mink; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Respiratory Mucosa; Signal Transduction; Staurosporine; Transforming Growth Factor beta; Transforming Growth Factor beta1

2005
Apoptosis of human endothelial cells is accompanied by proteolytic processing of latent TGF-beta binding proteins and activation of TGF-beta.
    Cell death and differentiation, 2005, Volume: 12, Issue:7

    Topics: Anoikis; Apoptosis; Caspase Inhibitors; Caspases; Cells, Cultured; Culture Media, Conditioned; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Endothelial Cells; Extracellular Matrix; Genes, Reporter; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Protein Processing, Post-Translational; Smad Proteins; Staurosporine; Trans-Activators; Transforming Growth Factor beta

2005
ERK-dependent signaling pathway and transcriptional factor Ets-1 regulate matrix metalloproteinase-9 production in transforming growth factor-beta1 stimulated glomerular podocytes.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2005, Volume: 16, Issue:4-6

    Topics: Animals; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Enzymologic; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mice; Podocytes; Proto-Oncogene Protein c-ets-1; Smad2 Protein; Staurosporine; Transforming Growth Factor beta; Transforming Growth Factor beta1

2005
Proteolytic activation of latent TGF-beta precedes caspase-3 activation and enhances apoptotic death of lung epithelial cells.
    Journal of cellular physiology, 2006, Volume: 207, Issue:2

    Topics: Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cell Adhesion; Cell Line; Cell Survival; Culture Media, Conditioned; Culture Media, Serum-Free; Epithelial Cells; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Lung; Mink; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Plasminogen Activator Inhibitor 1; Proto-Oncogene Proteins c-akt; Smad2 Protein; Staurosporine; Transfection; Transforming Growth Factor beta; Urokinase-Type Plasminogen Activator

2006
Parathyroid hormone increases beta-catenin levels through Smad3 in mouse osteoblastic cells.
    Endocrinology, 2006, Volume: 147, Issue:5

    Topics: Animals; Apoptosis; beta Catenin; Bone and Bones; Bone Development; Cell Line, Tumor; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Enzyme Inhibitors; Etoposide; Gene Expression Regulation; Isoquinolines; Lithium Chloride; Luciferases; Mice; Naphthalenes; NIH 3T3 Cells; Osteoblasts; Parathyroid Hormone; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad3 Protein; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Transforming Growth Factor beta

2006
Bystander macrophage apoptosis after Mycobacterium tuberculosis H37Ra infection.
    Infection and immunity, 2008, Volume: 76, Issue:1

    Topics: Apoptosis; Cell Communication; Cell Line, Tumor; Enzyme Inhibitors; fas Receptor; Humans; Macrophages; Mycobacterium tuberculosis; Myeloid Differentiation Factor 88; Neutrophils; Staurosporine; TNF-Related Apoptosis-Inducing Ligand; Toll-Like Receptor 2; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2008
TGFbeta protects mesoangioblasts from apoptosis via sphingosine kinase-1 regulation.
    Cellular signalling, 2009, Volume: 21, Issue:2

    Topics: Animals; Apoptosis; Blood Vessels; Caspase 3; Cell Survival; Cells, Cultured; MAP Kinase Signaling System; Mesoderm; Mice; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Isoforms; RNA, Small Interfering; Staurosporine; Stem Cells; Transforming Growth Factor beta; Up-Regulation

2009
Up-regulation of homeodomain genes, DLX1 and DLX2, by FLT3 signaling.
    Haematologica, 2011, Volume: 96, Issue:6

    Topics: Antigens, Surface; Cell Line, Tumor; Cell Nucleus; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Leukemic; Gene Silencing; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction; Smad2 Protein; Staurosporine; Transcription Factors; Transforming Growth Factor beta; Up-Regulation

2011
Influenza induces endoplasmic reticulum stress, caspase-12-dependent apoptosis, and c-Jun N-terminal kinase-mediated transforming growth factor-β release in lung epithelial cells.
    American journal of respiratory cell and molecular biology, 2012, Volume: 46, Issue:5

    Topics: Animals; Apoptosis; Caspase 12; Cells, Cultured; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Influenza A Virus, H1N1 Subtype; JNK Mitogen-Activated Protein Kinases; Lung; Mice; Mice, Inbred C57BL; Orthomyxoviridae Infections; Respiratory Mucosa; Staurosporine; Thapsigargin; Transcription Factors; Transforming Growth Factor beta; Viral Load

2012
Effects of all-trans retinoic acid on signal pathway of cyclooxygenase-2 and Smad3 in transforming growth factor-β-stimulated glomerular mesangial cells.
    Experimental biology and medicine (Maywood, N.J.), 2014, Volume: 239, Issue:3

    Topics: Animals; Apoptosis; Cell Line; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Fibrosis; Glomerular Mesangium; Mesangial Cells; Nitrobenzenes; Protein Transport; Rats; RNA, Messenger; Signal Transduction; Smad3 Protein; Smad7 Protein; Staurosporine; Sulfonamides; Thromboxane A2; Transforming Growth Factor beta; Tretinoin

2014
Targeting a cell state common to triple-negative breast cancers.
    Molecular systems biology, 2015, Feb-19, Volume: 11, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Delivery Systems; Female; Gene Expression Profiling; Humans; Intracellular Signaling Peptides and Proteins; Mice; Molecular Docking Simulation; Molecular Targeted Therapy; Protein Interaction Domains and Motifs; Protein-Tyrosine Kinases; Proteomics; Sequence Analysis, RNA; Signal Transduction; STAT3 Transcription Factor; Staurosporine; Syk Kinase; Transforming Growth Factor beta; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2015
Staurosporine induces chondrogenesis of chick embryo wing bud mesenchyme in monolayer cultures through canonical and non-canonical TGF-β pathways.
    In vitro cellular & developmental biology. Animal, 2016, Volume: 52, Issue:1

    Topics: Actin Cytoskeleton; Animals; Benzodioxoles; Chick Embryo; Chondrogenesis; Imidazoles; Mesoderm; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Signal Transduction; Smad Proteins; Staurosporine; Transforming Growth Factor beta; Wings, Animal

2016
[HBV-upregulated Lnc-HUR1 inhibits the apoptosis of liver cancer cells].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2022, Sep-25, Volume: 38, Issue:9

    Topics: Animals; Annexins; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Proliferation; Hep G2 Cells; Hepatitis B virus; Humans; Liver Neoplasms; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Proto-Oncogene Proteins c-bcl-2; RNA, Long Noncoding; Staurosporine; Transforming Growth Factor beta; Tumor Suppressor Protein p53

2022