staurosporine has been researched along with thiophenes in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonnekoh, B; Hegemann, L; Mahrle, G; Wevers, A | 1 |
| Bonnekoh, B; Fruchtmann, R; Hegemann, L; Mahrle, G; Müller-Peddinghaus, R; Schmidt, BH; Traber, J; van Rooijen, LA | 1 |
| Hegemann, L; Kempenaar, J; Ponec, M | 1 |
| Casas-González, P; García-Sáinz, JA; Ruiz-Martínez, A | 1 |
| Chen, XM; Chen, YD; Li, HF; Liu, HC; Lu, S; Lu, T; Ran, T; Yuan, HL | 1 |
| Dent, P; Eulitt, P; Mitchell, C; Park, M; Yacoub, A; Yang, C | 1 |
| Choy, ML; Lee, JH; Marks, PA; Ngo, L; Venta-Perez, G | 1 |
| Brown, EJ; Schoppy, DW | 1 |
| Aft, RL; Cai, S; Ellis, MJ; Goiffon, RJ; Guo, Z; Hoog, J; Li, S; Lin, L; Ma, CX; Piwnica-Worms, H; Prat, A; Ryan, CE; Schaiff, WT | 1 |
| Enkvist, E; Kasari, M; Ligi, K; Pålsson, LO; Uri, A; Vaasa, A; Viht, K; Williams, JA | 1 |
| Radha, V; Sayyad, Z; Sirohi, K; Swarup, G | 1 |
11 other study(ies) available for staurosporine and thiophenes
| Article | Year |
|---|---|
Changes of epidermal cell morphology and keratin expression induced by inhibitors of protein kinase C.
Topics: Alkaloids; Calmodulin; Cell Line; Humans; Indoles; Keratinocytes; Keratins; Piperidines; Protein Kinase C; Staurosporine; Thiophenes | 1992 |
Effects of tiflucarbine as a dual protein kinase C/calmodulin antagonist on proliferation of human keratinocytes and release of reactive oxygen species from human leukocytes.
Topics: Alkaloids; Calmodulin; Cell Division; Cells, Cultured; Humans; Indoles; Keratinocytes; Neutrophils; Oxygen; Protein Kinase C; Staurosporine; Sulfonamides; Thiophenes | 1991 |
The involvement of protein kinase C in proliferation and differentiation of human keratinocytes--an investigation using inhibitors of protein kinase C.
Topics: Alkaloids; Cell Differentiation; Cell Division; Humans; Indoles; Keratinocytes; Piperidines; Protein Kinase C; Staurosporine; Thiophenes | 1994 |
Lysophosphatidic acid induces alpha1B-adrenergic receptor phosphorylation through G beta gamma, phosphoinositide 3-kinase, protein kinase C and epidermal growth factor receptor transactivation.
Topics: Androstadienes; Animals; Cell Line; COS Cells; Enzyme Inhibitors; ErbB Receptors; Heterotrimeric GTP-Binding Proteins; Lysophospholipids; Models, Chemical; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protease Inhibitors; Protein Isoforms; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Staurosporine; Thiophenes; Transcriptional Activation; Tyrphostins; Wortmannin | 2003 |
Structure-based and shape-complemented pharmacophore modeling for the discovery of novel checkpoint kinase 1 inhibitors.
Topics: Benzodiazepinones; Binding Sites; Biocatalysis; Checkpoint Kinase 1; Drug Design; Ligands; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Protein Structure, Tertiary; Pyrazoles; Staurosporine; Structure-Activity Relationship; Thiophenes; Urea | 2010 |
Poly(ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in carcinoma cells.
Topics: Cell Death; Cell Line, Tumor; Checkpoint Kinase 1; Drug Synergism; Enzyme Activation; Histones; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Staurosporine; Thiophenes; Urea | 2010 |
Role of checkpoint kinase 1 (Chk1) in the mechanisms of resistance to histone deacetylase inhibitors.
Topics: Animals; Cell Line, Tumor; Cell Survival; Cells, Cultured; Checkpoint Kinase 1; DNA Damage; Drug Resistance; Fibroblasts; Foreskin; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunoblotting; Male; Mice; Protein Kinases; Quinolines; Quinuclidines; RNA Interference; Spleen; Staurosporine; Thiophenes; Urea; Vorinostat | 2011 |
Chk'ing p53-deficient breast cancers.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Checkpoint Kinase 1; Female; Humans; Molecular Targeted Therapy; Neoplasm Proteins; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Thiophenes; Tumor Suppressor Protein p53; Urea | 2012 |
Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Camptothecin; Cell Cycle; Cell Line, Tumor; Checkpoint Kinase 1; DNA Damage; DNA, Neoplasm; Female; Genes, cdc; Genes, erbB-2; Genes, p53; Humans; Irinotecan; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Targeted Therapy; Neoplasm Proteins; Protein Kinase Inhibitors; Protein Kinases; Receptors, Estrogen; Receptors, Progesterone; Staurosporine; Thiophenes; Tumor Suppressor Protein p53; Urea; Xenograft Model Antitumor Assays | 2012 |
Responsive microsecond-lifetime photoluminescent probes for analysis of protein kinases and their inhibitors.
Topics: Algorithms; Anisotropy; Binding Sites; Binding, Competitive; Biocatalysis; Fluorescent Dyes; Kinetics; Lysine; Models, Chemical; Molecular Structure; Protein Binding; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Spectrophotometry; Staurosporine; Thiophenes; Time Factors | 2013 |
661W is a retinal ganglion precursor-like cell line in which glaucoma-associated optineurin mutants induce cell death selectively.
Topics: Animals; Apoptosis; Biomarkers; Cell Cycle Proteins; Cell Differentiation; Cell Line; DNA-Binding Proteins; Eye Proteins; Glaucoma; Membrane Transport Proteins; Mice; Microtubule-Associated Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Neural Stem Cells; Nuclear Proteins; Pyrimidines; Retinal Ganglion Cells; Staurosporine; Thiophenes; Thy-1 Antigens; Transcription Factor Brn-3C; Tubulin | 2017 |