staurosporine has been researched along with sq-23377 in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.90) | 18.7374 |
| 1990's | 55 (79.71) | 18.2507 |
| 2000's | 8 (11.59) | 29.6817 |
| 2010's | 4 (5.80) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fenton, JW; Garcia, JG; Natarajan, V | 1 |
| Alexandre, A; Deana, R; Donella-Deana, A; Francesconi, M; Ruzzene, M | 1 |
| Graham, CS; Tashjian, AH | 1 |
| Balla, T; Catt, KJ; Clark, AJ; Jones, MR | 1 |
| Desai, SN; Letts, GL; Myers, CL; Schembri-King, J; Wallace, RW | 1 |
| Matsui, S; Matsumoto, Y; Tanimura, A; Tojyo, Y | 2 |
| González, AV; Maghazachi, AA; Phillips-Quagliata, JM; Rao, TD | 1 |
| Gilfillan, AM; Lin, P | 1 |
| Joseph, S; MacDermot, J | 1 |
| Breitbart, H; Homonnai, ZT; Kalina, M; Lax, J; Naor, Z; Paz, GF; Rotem, R | 1 |
| Hazeki, O; Kume, S; Ui, M; Yatomi, Y | 1 |
| Schatz-Munding, M; Ullrich, V | 1 |
| Ichikawa, A; Negishi, M; Ohnishi, M; Takahashi, S | 1 |
| Kwan-Yeung, L; Turkson, J; Wong, K | 1 |
| Burgess, GM; Coote, PR; Dunn, PM; Rang, HP; Wood, JN | 1 |
| Elmore, M; Kellie, S; Murphy, CT; Westwick, J | 1 |
| Almeida, HI; Balazovich, KJ; Boxer, LA | 1 |
| Berezesky, IK; Fargnoli, J; Holbrook, NJ; Maki, A; Trump, BF | 1 |
| Apgar, JR | 1 |
| Alexandre, A; Cavallini, L; Deana, R; Doni, MG; Francesconi, MA; Ruzzene, M; Zoccarato, F | 1 |
| Francis, J; Pon, DJ; Qu, Y; Sen, AK; Torchia, J | 1 |
| Braquet, P; Ferber, E; Fischer, G; Harell, T; Her, E; Naor, Z; Reiss, N; Zor, U | 1 |
| Dan-Cohen, H; Naor, Z | 1 |
| Iaizzo, PA; Olsen, RA; Powis, G; Seewald, MJ; Sehgal, I | 1 |
| Gimbrone, MA; Hrbolich, JK; Schafer, AI; Zavoico, GB | 1 |
| Aviv, A; Gardner, JP; Kimura, M | 1 |
| Homonnai, ZT; Kalina, M; Naor, Z; Paz, GF; Rotem, R | 1 |
| Goodrum, DD; Sachs, G; Wheeler, LA | 1 |
| Banga, HS; Feinstein, MB; Halenda, SP; Lau, LF; Zavoico, GB | 1 |
| Perianin, A; Synderman, R | 1 |
| Di Virgilio, F; Foresta, C; Rossato, M | 1 |
| Matsumoto, Y; Sugiya, H; Tanimura, A; Tojyo, Y | 1 |
| Dissing, S; Gromada, J; Jørgensen, TD | 1 |
| Contrera, JG; Rosenzweig, BA; Sistare, FD | 1 |
| Alexandre, A; Deana, R; Doni, MG; Francesconi, MA; Padoin, E | 1 |
| Distler, A; Haller, H; Lindschau, C; Luft, FC; Quass, P | 1 |
| Agell, N; Bachs, O; Bosch, M; López-Girona, A | 1 |
| Foder, B; Scharff, O | 1 |
| Alexandre, A; Cavallini, L | 1 |
| Emerling, D; Hashimoto, Y; Horie, Y; Kinoshita, M; Kurokawa, K; Nakao, A; Tsukamoto, K; Watanabe, T | 1 |
| MacDermot, J; McEwan, JR; Parsaee, H | 1 |
| Mitchell, R; Thomson, FJ | 1 |
| Bond, M; Damron, DS; Moravec, CS; Van Wagoner, DR | 1 |
| Dana, R; Leto, TL; Levy, R; Malech, HL | 1 |
| Geibel, J; Giebisch, G; Wang, WH | 1 |
| Goligorsky, MS; Gordienko, DV; Tsukahara, H | 1 |
| Rothstein, TL; Wang, Z; Xie, H | 1 |
| Balasubramanyam, M; Gardner, JP | 1 |
| Sochanowicz, B; Szumiel, I | 1 |
| Leach, KL; Ruff, VA; Scott, JE | 1 |
| Puschner, B; Schacht, J | 1 |
| Adachi, M; Date, M; Fukuhara, S; Katsurada, T; Kido, H; Kimura, T; Kishimoto, Y; Yamanaka, Y | 1 |
| Howard, BP; Jenkens, MK; Kagey-Sobotka, A; Lichtenstein, LM; MacGlashan, DW; Schroeder, JT | 1 |
| Aten, J; Roos, A; Schilder-Tol, EJ; Weening, JJ | 1 |
| Ciereszko, RE; Guan, Z; Ottobre, AC; Ottobre, JS; Petroff, BK; Stokes, BT | 1 |
| Florio, T; Giordano, G; Giusti, M; Schettini, G; Thellung, S; Valenti, S | 1 |
| Chin, TY; Chueh, SH | 1 |
| Blauvelt, A; Davis, DA; Moses, AV; Orenstein, JM; Overwijk, WW; Rinderknecht, AS; Yarchoan, R; Zoeteweij, JP | 1 |
| Hashimoto, N; Morita, T; Nezu, A; Tanimura, A; Tojyo, Y | 1 |
| Hirt, UA; Leist, M | 1 |
| Edwards, JM; Kempson, SA; Sturek, M | 1 |
| Affar, el B; Calvo, D; Gay, F; Li, E; Luke, MP; Shi, Y; Sui, G; Weiss, RS | 1 |
| Daily, WJ; Eric Hesselberth, P; Moravec, RA; Niles, AL; Riss, TL; Scurria, MA | 1 |
| Manabe, K; Okada, Y; Sabirov, RZ; Zamaraeva, MV | 1 |
| Chang, CJ; Chen, MT; Chen, SE; Chiang, CC; Nagahata, H; Peh, HC; Yu, B | 1 |
| Focht, DC; Gregg, JL; McGuire, KM; Model, MA | 1 |
| Morán, J; Ortega, A | 1 |
| Allday, MJ; Anderton, E; White, RE; Yee, J | 1 |
69 other study(ies) available for staurosporine and sq-23377
| Article | Year |
|---|---|
Thrombin stimulation of human endothelial cell phospholipase D activity. Regulation by phospholipase C, protein kinase C, and cyclic adenosine 3'5'-monophosphate.
Topics: Adenylate Cyclase Toxin; Alkaloids; Bucladesine; Calcimycin; Cell Membrane; Cells, Cultured; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Humans; Ionomycin; Kinetics; Models, Biological; Phorbol Esters; Phospholipase D; Protein Kinase C; Sodium Fluoride; Staurosporine; Thrombin; Type C Phospholipases; Umbilical Veins; Virulence Factors, Bordetella | 1992 |
The antioxidant butylated hydroxytoluene (BHT) inhibits the dioctanoylglycerol-evoked platelet response but potentiates that elicited by ionomycin.
Topics: Adenosine Triphosphate; Alkaloids; Arachidonic Acid; Blood Platelets; Butylated Hydroxytoluene; Diglycerides; Drug Synergism; Humans; In Vitro Techniques; Ionomycin; Kinetics; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Staurosporine | 1992 |
Mechanisms of activation of Na+/H+ exchange in human osteoblast-like SaOS-2 cells.
Topics: Alkaloids; Calcium; Carrier Proteins; Cell Line; Cytosol; Egtazic Acid; Fluoresceins; Fluorescent Dyes; Fura-2; Humans; Hydrogen-Ion Concentration; Ionomycin; Nigericin; Osmotic Pressure; Osteoblasts; Protein Kinase C; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Stimulation of early gene expression by angiotensin II in bovine adrenal glomerulosa cells: roles of calcium and protein kinase C.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenocorticotropic Hormone; Alkaloids; Angiotensin II; Animals; Base Sequence; Calcium; Cattle; Cells, Cultured; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Genes, fos; Genes, jun; Imidazoles; Ionomycin; Molecular Sequence Data; Protein Kinase C; Pyridines; Staurosporine; Stimulation, Chemical; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factors; Zona Glomerulosa | 1992 |
Discriminatory effects of protein kinase inhibitors and calcium ionophore on endothelial ICAM-1 induction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Calcimycin; Cell Adhesion Molecules; Cell Survival; Cytokines; Drug Synergism; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Ionomycin; Isoquinolines; Lipopolysaccharides; Piperazines; Protein Biosynthesis; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Relationship between cytosolic Ca2+ concentration and amylase release in rat parotid acinar cells following muscarinic stimulation.
Topics: Alkaloids; Amylases; Animals; Calcium; Carbachol; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Gallic Acid; Ionomycin; Male; Parotid Gland; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
A novel IgA receptor expressed on a murine B cell lymphoma.
Topics: Alkaloids; Animals; Binding, Competitive; Cycloheximide; Down-Regulation; Hydrogen-Ion Concentration; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; In Vitro Techniques; Ionomycin; Lymphocyte Activation; Lymphoma, B-Cell; Mice; Mice, Inbred BALB C; Naphthalenes; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Polycyclic Compounds; Protein Kinase C; Receptors, Fc; Receptors, Immunologic; Rosette Formation; Secretory Component; Staurosporine; Tetradecanoylphorbol Acetate; Trypsin; Tumor Cells, Cultured | 1992 |
The role of calcium and protein kinase C in the IgE-dependent activation of phosphatidylcholine-specific phospholipase D in a rat mast (RBL 2H3) cell line.
Topics: Alkaloids; Animals; Calcium; Cell Line; Enzyme Activation; Histamine Release; Immunoglobulin E; Indoles; Ionomycin; Kinetics; Maleimides; Mast Cells; Phospholipase D; Protein Kinase C; Rats; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Thrombin promotes actin polymerization in U937 human monocyte-macrophage cells. Analysis of the signalling mechanisms mediating actin polymerization.
Topics: Actins; Alkaloids; Calcium; Cations, Divalent; Cell Line; Chemotaxis, Leukocyte; GTP-Binding Proteins; Humans; Indoles; Ionomycin; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Polymers; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Virulence Factors, Bordetella | 1992 |
Ca(2+)-independent induction of acrosome reaction by protein kinase C in human sperm.
Topics: Acrosome; Adult; Alkaloids; Calcium; Cell Membrane Permeability; Diglycerides; Down-Regulation; Exocytosis; Female; Humans; Immunohistochemistry; Ionomycin; Male; Microscopy, Electron; Protein Kinase C; Signal Transduction; Sperm Capacitation; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Suppression by wortmannin of platelet responses to stimuli due to inhibition of pleckstrin phosphorylation.
Topics: Alkaloids; Androstadienes; Blood Platelets; Blood Proteins; Calcium; Collagen; Humans; Ionomycin; Phosphates; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Serotonin; Staurosporine; Tetradecanoylphorbol Acetate; Wortmannin | 1992 |
Priming of human polymorphonuclear leukocytes with granulocyte-macrophage colony-stimulating factor involves protein kinase C rather than enhanced calcium mobilisation.
Topics: Alkaloids; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Cations, Divalent; Chromatography, High Pressure Liquid; Cycloheximide; Dactinomycin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ionomycin; Leukotrienes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Involvement of protein kinase C in thrombin-induced translocation of Gi2 alpha from the membrane to the cytosol in mouse mastocytoma P-815 cells.
Topics: Adenosine Diphosphate Ribose; Alkaloids; Animals; Biological Transport; Cell Membrane; Cytosol; Enzyme Activation; GTP-Binding Proteins; In Vitro Techniques; Ionomycin; Mast Cells; Mice; Pertussis Toxin; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Staurosporine clamps cytosolic free Ca2+ concentrations of human neutrophils.
Topics: Alkaloids; Calcium; Cytosol; Fura-2; Glucuronidase; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ionomycin; Kinetics; Lysosomes; Manganese; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Protein Kinase C; Spectrometry, Fluorescence; Staurosporine; Virulence Factors, Bordetella | 1992 |
Bradykinin evoked depolarization of a novel neuroblastoma x DRG neurone hybrid cell line (ND7/23).
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcium; Cell Membrane; Cells, Cultured; Cytosol; Evoked Potentials; Ganglia, Spinal; Hybrid Cells; Inositol Phosphates; Ionomycin; Membrane Potentials; Neuroblastoma; Neurons; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Receptors, Bradykinin; Receptors, Neurotransmitter; Second Messenger Systems; Staurosporine | 1991 |
Comparison of the role of protein kinase C in platelet functional responses induced by three different mechanisms, PAF, ionomycin and arachidonic acid.
Topics: Alkaloids; Animals; Arachidonic Acid; Calcium; Feedback; Ionomycin; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Membrane Glycoproteins; Protein Kinase C; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1991 |
Recombinant human G-CSF and GM-CSF prime human neutrophils for superoxide production through different signal transduction mechanisms.
Topics: Alkaloids; Cinnamates; Dose-Response Relationship, Drug; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; GTP-Binding Proteins; Humans; In Vitro Techniques; Ionomycin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Recombinant Proteins; Respiratory Burst; Signal Transduction; Staurosporine; Sulfides; Superoxides | 1991 |
Role of [Ca2+]i in induction of c-fos, c-jun, and c-myc mRNA in rat PTE after oxidative stress.
Topics: Alkaloids; Animals; Benzamides; Blotting, Northern; Calcium; Catalase; Cell Hypoxia; Cycloheximide; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, fos; Genes, jun; Genes, myc; In Vitro Techniques; Ionomycin; Kidney Tubules; Male; Protein Kinase C; Rats; Rats, Inbred F344; RNA, Messenger; Staurosporine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Xanthine; Xanthines | 1992 |
Regulation of the antigen-induced F-actin response in rat basophilic leukemia cells by protein kinase C.
Topics: Actins; Alkaloids; Animals; Antibodies, Monoclonal; Antigens, Differentiation, B-Lymphocyte; Calcium; Carbazoles; Cell Line; Diglycerides; Immunoglobulin E; Indole Alkaloids; Ionomycin; Kinetics; Leukemia, Basophilic, Acute; Leukemia, Experimental; Macromolecular Substances; Protein Kinase C; Rats; Receptors, Fc; Receptors, IgE; Serotonin; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Platelet responses promoted by the activation of protein kinase C or the increase of cytosolic Ca2+ are potentiated by adrenaline. Effects of cAMP and staurosporine.
Topics: Alkaloids; Blood Platelets; Calcium; Cyclic AMP; Cytosol; Enzyme Activation; Epinephrine; Humans; Ionomycin; Platelet Activation; Platelet Aggregation; Protein Kinase C; Staurosporine; Type C Phospholipases | 1991 |
Carbachol-stimulated phosphorylation of a 170-kDa endogenous protein in avian salt gland cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Atropine; Carbachol; Ducks; Ionomycin; Isoquinolines; Kinetics; Molecular Weight; Phosphates; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Proteins; Salt Gland; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Arachidonic acid release by basophilic leukemia cells and macrophages stimulated by Ca2+ ionophores, antigen and diacylglycerol: essential role for protein kinase C and prevention by glucocorticosteroids.
Topics: Alkaloids; Animals; Antigens; Arachidonic Acids; Calcimycin; Carbazoles; Cell Line; Cell Membrane; Cells, Cultured; Dexamethasone; Immunoglobulin E; Indole Alkaloids; Ionomycin; Kinetics; Leukemia, Basophilic, Acute; Leukemia, Experimental; Macrophages; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Serum Albumin, Bovine; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Mechanism of action of gonadotropin releasing hormone upon gonadotropin secretion: involvement of protein kinase C as revealed by staurosporine inhibition and enzyme depletion.
Topics: Alkaloids; Animals; Buserelin; Calcium; Cells, Cultured; Diglycerides; Female; Gonadotropin-Releasing Hormone; Ionomycin; Luteinizing Hormone; Phosphatidylserines; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Platelet-derived growth factor stimulates non-mitochondrial Ca2+ uptake and inhibits mitogen-induced Ca2+ signaling in Swiss 3T3 fibroblasts.
Topics: Alkaloids; Animals; Biological Transport, Active; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Dinoprostone; Fibroblasts; Ionomycin; Kinetics; Mice; Mitogens; Phospholipid Ethers; Platelet-Derived Growth Factor; Protein Kinase C; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1990 |
Enhancement of thrombin- and ionomycin-stimulated prostacyclin and platelet-activating factor production in cultured endothelial cells by a tumor-promoting phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Arachidonic Acids; Calcimycin; Cells, Cultured; Dinoprost; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Ionomycin; Isoquinolines; Phorbol Esters; Phospholipases A; Phospholipases A2; Piperazines; Platelet Activating Factor; Prostaglandin D2; Prostaglandins H; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Agonist-evoked alkaline shift in the cytosolic pH set point for activation of Na+/H+ antiport in human platelets. The role of cytosolic Ca2+ and protein kinase C.
Topics: Alkaloids; Blood Platelets; Calcium; Carrier Proteins; Humans; Hydrogen-Ion Concentration; Ionomycin; Kinetics; Protein Kinase C; Sodium-Hydrogen Exchangers; Staurosporine; Thrombin; Vasopressins | 1990 |
Further studies on the involvement of protein kinase C in human sperm flagellar motility.
Topics: Adult; Alkaloids; Diglycerides; Humans; Immunohistochemistry; Ionomycin; Male; Protein Kinase C; Sperm Motility; Spermatozoa; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Role of protein kinase C in the regulation of cytosolic Ca2+ in A431 cells: separation of growth factor and bradykinin pathways.
Topics: Alkaloids; Bradykinin; Calcium; Cytosol; Down-Regulation; Epidermal Growth Factor; Humans; Ionomycin; Manganese; Protein Kinase C; Pyrimidinones; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thiazoles; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1990 |
Synergistic release of arachidonic acid from platelets by activators of protein kinase C and Ca2+ ionophores. Evidence for the role of protein phosphorylation in the activation of phospholipase A2 and independence from the Na+/H+ exchanger.
Topics: Adenosine Triphosphate; Alkaloids; Amiloride; Arachidonic Acids; Aspirin; Blood Platelets; Calcimycin; Carrier Proteins; Enzyme Activation; Humans; Indoles; Ionomycin; Ionophores; Kinetics; Lactams; Phospholipases; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1989 |
Analysis of calcium homeostasis in activated human polymorphonuclear leukocytes. Evidence for two distinct mechanisms for lowering cytosolic calcium.
Topics: Alkaloids; Benzofurans; Calcium; Cytosol; Diglycerides; Ethers; Fura-2; Homeostasis; Humans; In Vitro Techniques; Ionomycin; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Carbachol-induced potassium release in rat parotid acini: comparison of the roles of cytosolic Ca2+ and protein kinase C.
Topics: Alkaloids; Amylases; Animals; Calcium; Calcium Channel Blockers; Carbachol; Cytosol; Egtazic Acid; Enzyme Activation; Gallic Acid; Ionomycin; Male; Parotid Gland; Potassium; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1993 |
Differential modulation by protein kinase C of progesterone-activated responses in human sperm.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Calcium; Cell Membrane; Fluorescent Dyes; Fura-2; Gramicidin; Humans; In Vitro Techniques; Ionomycin; Isoquinolines; Kinetics; Male; Membrane Potentials; Piperazines; Progesterone; Protein Kinase C; Spermatozoa; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Staurosporine enhances Ca2+ entry induced by depletion of intracellular Ca2+ stores in rat parotid acinar cells.
Topics: Alkaloids; Animals; Calcium; Calcium-Transporting ATPases; Carbachol; Enzyme Inhibitors; In Vitro Techniques; Intracellular Fluid; Ion Transport; Ionomycin; Ionophores; Male; Manganese; Muscarinic Agonists; Parotid Gland; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Terpenes; Thapsigargin | 1995 |
Role of protein kinase C in the regulation of inositol phosphate production and Ca2+ mobilization evoked by ATP and acetylcholine in rat lacrimal acini.
Topics: Acetylcholine; Adenosine Triphosphate; Alkaloids; Animals; Calcium; Inositol; Ionomycin; Lacrimal Apparatus; Male; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Time Factors | 1995 |
P2 purinergic receptors potentiate parathyroid hormone receptor-mediated increases in intracellular calcium and inositol trisphosphate in UMR-106 rat osteoblasts.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Calcium; Inositol 1,4,5-Trisphosphate; Ionomycin; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Rats; Receptors, Parathyroid Hormone; Receptors, Purinergic P2; Staurosporine; Teriparatide; Tumor Cells, Cultured; Uridine Triphosphate | 1995 |
Staurosporine-independent platelet aggregation induced by the calcium ionophore ionomycin is inhibited by prostacyclin and sodium nitroprusside and stimulated by adrenaline.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Bucladesine; Calcium; Cyclic GMP; Epinephrine; Epoprostenol; Humans; Ionomycin; Nitroprusside; Phosphoproteins; Platelet Aggregation; Protein Kinase C; Staurosporine; Yohimbine | 1993 |
Nuclear calcium signaling is initiated by cytosolic calcium surges in vascular smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Angiotensin II; Animals; Calcium; Cell Nucleus; Cells, Cultured; Cytosol; Ionomycin; Isoquinolines; Kinetics; Microscopy, Confocal; Muscle, Smooth, Vascular; Piperazines; Potassium Chloride; Protein Kinase C; Rats; Second Messenger Systems; Signal Transduction; Staurosporine; Terpenes; Thapsigargin | 1994 |
Protein kinase C regulates calmodulin expression in NRK cells activated to proliferate from quiescence.
Topics: Alkaloids; Animals; Calmodulin; Cattle; Cell Division; Cell Line; Contact Inhibition; Culture Media; Culture Media, Serum-Free; Cyclic AMP-Dependent Protein Kinases; DNA Replication; Epithelial Cells; Epithelium; Fetal Blood; Gene Expression Regulation; Ionomycin; Isoquinolines; Kidney; Protein Kinase C; Rats; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Delayed activation of plasma membrane Ca2+ pump in human neutrophils.
Topics: Adenosine Triphosphate; Alkaloids; Biological Transport; Calcium; Calcium Channels; Calcium Chloride; Calcium-Transporting ATPases; Calmodulin; Cations, Divalent; Cell Membrane Permeability; Choline; Culture Media; Cytosol; Econazole; Egtazic Acid; Humans; Ionomycin; Monensin; Neutrophils; Protein Kinase C; Staurosporine; Sulfonamides; Terpenes; Thapsigargin | 1994 |
Ca2+ efflux from platelets. Control by protein kinase C and the filling state of the intracellular Ca2+ stores.
Topics: Alkaloids; Blood Platelets; Calcium; Calcium Radioisotopes; Calcium-Transporting ATPases; Cytoplasmic Granules; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Exocytosis; Fluorescent Dyes; Humans; In Vitro Techniques; Indoles; Ionomycin; Kinetics; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin | 1994 |
Prostaglandin F2 alpha enhances tyrosine phosphorylation and DNA synthesis through phospholipase C-coupled receptor via Ca(2+)-dependent intracellular pathway in NIH-3T3 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Calcium; Dinoprost; DNA; Ionomycin; Isoquinolines; Mice; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Receptors, Prostaglandin; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Type C Phospholipases; Tyrosine | 1994 |
Bradykinin-induced release of PGI2 from aortic endothelial cell lines: responses mediated selectively by Ca2+ ions or a staurosporine-sensitive kinase.
Topics: 6-Ketoprostaglandin F1 alpha; Alkaloids; Animals; Aorta, Thoracic; Arginine; Bradykinin; Calcium; Cattle; Cell Line; Endothelium, Vascular; Epoprostenol; Ionomycin; Nitric Oxide; omega-N-Methylarginine; Phosphotransferases; Signal Transduction; Staurosporine | 1993 |
Differential involvement of phospholipase A2 in phorbol ester-induced luteinizing hormone and growth hormone release from rat anterior pituitary tissue.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminobenzoates; Animals; Arachidonic Acid; Aristolochic Acids; Chlorobenzoates; Cinnamates; Cyclohexanones; Cycloheximide; Enzyme Activation; Female; Growth Hormone; Indoles; Ionomycin; Isoquinolines; Luteinizing Hormone; Melitten; ortho-Aminobenzoates; Phenanthrenes; Phenothiazines; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Piperazines; Pituitary Gland, Anterior; Proestrus; Protein Kinase C; Quinacrine; Rats; Rats, Wistar; Signal Transduction; Staurosporine | 1993 |
Arachidonic acid and endothelin potentiate Ca2+ transients in rat cardiac myocytes via inhibition of distinct K+ channels.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Alkaloids; Animals; Arachidonic Acid; Calcium; Cells, Cultured; Endothelins; Heart Ventricles; Ionomycin; Membrane Potentials; Myocardial Contraction; Myocardium; Potassium Channel Blockers; Potassium Chloride; Protein Kinase Inhibitors; Rats; Staurosporine; Thionucleotides; Ventricular Function | 1993 |
The requirement of p47 phosphorylation for activation of NADPH oxidase by opsonized zymosan in human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blood Proteins; Cell Membrane; Cytosol; Enzyme Activation; Humans; Ionomycin; Isoquinolines; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phosphates; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Mechanism of apical K+ channel modulation in principal renal tubule cells. Effect of inhibition of basolateral Na(+)-K(+)-ATPase.
Topics: Alkaloids; Animals; Calcium; Calcium-Transporting ATPases; Down-Regulation; Female; Hydrogen-Ion Concentration; Ionomycin; Kidney Tubules; Male; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Staurosporine; Strophanthidin | 1993 |
Continuous monitoring of nitric oxide release from human umbilical vein endothelial cells.
Topics: Alkaloids; Arginine; Bradykinin; Cells, Cultured; Colforsin; Endothelium, Vascular; Enzyme Activation; Humans; Ionomycin; Kinetics; Nitric Oxide; Polarography; Protein Kinase C; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Umbilical Veins | 1993 |
Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibodies, Anti-Idiotypic; Antigens, CD; B-Lymphocytes; B7-2 Antigen; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Immunoglobulins; Ionomycin; Isoquinolines; Lymphoma, B-Cell; Membrane Glycoproteins; Mice; Molecular Sequence Data; Phosphorylation; Piperazines; Protein Kinase C; Rats; Receptors, Antigen, B-Cell; Signal Transduction; Staurosporine; Sulfonamides | 1996 |
Protein kinase C modulates cytosolic free calcium by stimulating calcium pump activity in Jurkat T cells.
Topics: Alkaloids; Calcium; Calcium-Transporting ATPases; Cytosol; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Ionomycin; Ionophores; Lanthanum; Leukemia; Naphthalenes; Phorbol Esters; Protein Kinase C; Sodium; Staurosporine; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1995 |
Arachidonic acid metabolism in murine lymphoma cell sublines differing in radiation sensitivity.
Topics: Animals; Arachidonic Acid; Calcimycin; Cell Line; Hydrogen Peroxide; Hydroxyeicosatetraenoic Acids; Ionomycin; Lymphoma; Mice; Phospholipids; Prostaglandins; Radiation Tolerance; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; X-Rays | 1996 |
Dynamic equilibrium between calcineurin and kinase activities regulates the phosphorylation state and localization of the nuclear factor of activated T-cells.
Topics: Animals; Calcineurin; Calmodulin-Binding Proteins; Cell Line; Cell Nucleus; Cold Temperature; DNA-Binding Proteins; Enzyme Inhibitors; Immunosuppressive Agents; Indoles; Ionomycin; Ionophores; Kinetics; Lymphocyte Activation; Maleimides; Mice; NFATC Transcription Factors; Nuclear Proteins; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Staurosporine; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription Factors | 1997 |
Calmodulin-dependent protein kinases mediate calcium-induced slow motility of mammalian outer hair cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Azepines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hair Cells, Auditory, Outer; Ionomycin; Ionophores; Isoquinolines; Myosin-Light-Chain Kinase; Naphthalenes; Phosphorylation; Staurosporine; Sulfonamides | 1997 |
Induction of apoptosis in megakaryocytic leukemia cell lines by MX2, a morpholino anthracycline.
Topics: Antibiotics, Antineoplastic; Apoptosis; Benzoquinones; Carubicin; DNA Fragmentation; Enzyme Inhibitors; Humans; Ionomycin; Lactams, Macrocyclic; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Microscopy, Electron; Protein-Tyrosine Kinases; Quinones; Rifabutin; Staurosporine; Tumor Cells, Cultured | 1997 |
IL-4 secretion and histamine release by human basophils are differentially regulated by protein kinase C activation.
Topics: Basophils; Calcium; Cells, Cultured; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Histamine Release; Humans; Interleukin-4; Ionomycin; Ionophores; Lymphocytes; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1998 |
Strong expression of CD134 (OX40), a member of the TNF receptor family, in a T helper 2-type cytokine environment.
Topics: Animals; Autoimmunity; CD4-Positive T-Lymphocytes; Cells, Cultured; Cytokines; Drug Synergism; Female; Gene Expression Regulation; Interferon-gamma; Interleukin-4; Ionomycin; Mercuric Chloride; Protein Kinase Inhibitors; Rats; Rats, Inbred BN; Receptors, Immunologic; Receptors, OX40; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Th2 Cells; Tumor Necrosis Factor Receptor Superfamily, Member 7; Tumor Necrosis Factor-alpha | 1998 |
Assessment of the mechanism by which prolactin stimulates progesterone production by early corpora lutea of pigs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carcinogens; Cells, Cultured; Corpus Luteum; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Female; Ionomycin; Ionophores; Lipoproteins, LDL; Luteal Phase; Phorbol 12,13-Dibutyrate; Progesterone; Prolactin; Protein Kinase C; Staurosporine; Stimulation, Chemical; Swine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
A novel mechanism for the melatonin inhibition of testosterone secretion by rat Leydig cells: reduction of GnRH-induced increase in cytosolic Ca2+.
Topics: 17-alpha-Hydroxyprogesterone; Animals; Arachidonic Acid; Calcium; Calcium Signaling; Cells, Cultured; Drug Synergism; Fura-2; Gonadotropin-Releasing Hormone; Ionomycin; Leydig Cells; Luteinizing Hormone; Male; Melatonin; Pertussis Toxin; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Testosterone; Tetradecanoylphorbol Acetate; Thapsigargin; Virulence Factors, Bordetella | 1999 |
Distinct Ca(2+) signalling mechanisms induced by ATP and sphingosylphosphorylcholine in porcine aortic smooth muscle cells.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Calcium; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Cyclic AMP; Egtazic Acid; Estrenes; Imidazoles; Ionomycin; Manganese; Muscle, Smooth, Vascular; Phosphorylcholine; Pyrrolidinones; Sphingosine; Staurosporine; Swine; Thapsigargin; Thionucleosides; Thionucleotides; Virulence Factors, Bordetella | 2000 |
Targeted inhibition of calcineurin signaling blocks calcium-dependent reactivation of Kaposi sarcoma-associated herpesvirus.
Topics: Calcineurin; Calcineurin Inhibitors; Calcium Signaling; Capsid; Cells, Cultured; Cyclosporine; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Herpesvirus 8, Human; Humans; Indoles; Ionomycin; Maleimides; Microscopy, Electron; NFATC Transcription Factors; Nuclear Proteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factors; Transcription, Genetic; Transfection; Viral Proteins; Virus Activation | 2001 |
Interplay between calcium, diacylglycerol, and phosphorylation in the spatial and temporal regulation of PKCalpha-GFP.
Topics: Adenosine Triphosphate; Calcium; Carcinogens; Cell Line; Cell Membrane; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Green Fluorescent Proteins; Humans; Ionomycin; Ionophores; Isoenzymes; Luminescent Proteins; Magnesium; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Recombinant Fusion Proteins; Saponins; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 2002 |
Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells.
Topics: Animals; Annexin A5; Antibodies, Monoclonal; Apoptosis; Calcium; CD36 Antigens; Cell Line; Cell Membrane; Cells, Cultured; Escherichia coli; Formaldehyde; Humans; Inflammation; Ionomycin; Jumonji Domain-Containing Histone Demethylases; Jurkat Cells; Lipopolysaccharide Receptors; Liposomes; Macrophages; Membrane Lipids; Mice; Microglia; Microscopy, Confocal; Microscopy, Fluorescence; Necrosis; Oligomycins; Oligopeptides; Phagocytosis; Phosphatidylserines; Polymers; Receptors, Cell Surface; Staurosporine; Tumor Necrosis Factor-alpha | 2003 |
Inhibition of the renal betaine transporter by calcium ions.
Topics: Animals; Biological Transport; Calcium; Carrier Proteins; Cell Line; Cell Membrane; Dogs; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; GABA Plasma Membrane Transport Proteins; Hypertonic Solutions; Ionomycin; Kidney; Phorbol Esters; Protein Kinase C; Signal Transduction; Staurosporine; Thapsigargin | 2006 |
Targeted ablation of Par-4 reveals a cell type-specific susceptibility to apoptosis-inducing agents.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Calcimycin; Doxorubicin; Etoposide; Fibroblasts; HeLa Cells; Humans; Ionomycin; Mice; Mice, Knockout; Protein Structure, Tertiary; RNA Interference; Staurosporine | 2006 |
A homogeneous assay to measure live and dead cells in the same sample by detecting different protease markers.
Topics: Apoptosis; Biomarkers; Cell Line; Cell Line, Tumor; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Fluorescent Dyes; HCT116 Cells; HeLa Cells; HL-60 Cells; Humans; Ionomycin; Jurkat Cells; Peptide Hydrolases; Rhodamines; Staurosporine; U937 Cells | 2007 |
Ca(2+)-dependent glycolysis activation mediates apoptotic ATP elevation in HeLa cells.
Topics: Adenosine Triphosphate; Apoptosis; Calcium; Chelating Agents; Cytosol; Deoxyglucose; Egtazic Acid; Glycolysis; HeLa Cells; Humans; Iodoacetamide; Ionomycin; Ionophores; Luciferases; Mitochondria; Oxidative Phosphorylation; Pentachlorophenol; Sodium Fluoride; Staurosporine; Transfection; Uncoupling Agents | 2007 |
Calcium homeostasis and its relationship to superoxide production in blood and milk neutrophils of lactating goats.
Topics: Animals; Apoptosis; Calcium; Female; Goats; Homeostasis; Immunity, Innate; In Vitro Techniques; Ionomycin; Ionophores; Lactation; Mammary Glands, Animal; Milk; Neutrophils; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 2010 |
Measurement of the thickness and volume of adherent cells using transmission-through-dye microscopy.
Topics: Animals; Benzenesulfonates; Cell Size; Cells, Cultured; Humans; Hypotonic Solutions; Ionomycin; Mice; Microscopy; Microscopy, Confocal; NIH 3T3 Cells; Osmolar Concentration; Staurosporine; Urinary Bladder | 2010 |
Role of cytoskeleton proteins in the morphological changes during apoptotic cell death of cerebellar granule neurons.
Topics: Actins; Animals; Apoptosis; Calpain; Caspase 3; Caspase Inhibitors; Cells, Cultured; Cerebellum; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Ionomycin; Ionophores; Neurons; Potassium; Rats; Rats, Wistar; Staurosporine; Tubulin | 2011 |
Latent Epstein-Barr virus can inhibit apoptosis in B cells by blocking the induction of NOXA expression.
Topics: Apoptosis; B-Lymphocytes; Cell Line; Drug Resistance, Viral; Etoposide; Gene Deletion; Gene Expression Regulation, Viral; Gene Knockout Techniques; Genetic Loci; Herpesvirus 4, Human; Humans; Ionomycin; Proto-Oncogene Proteins c-bcl-2; Reproducibility of Results; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Staurosporine; Viral Proteins; Virus Latency | 2011 |