Compounds > staurosporine
Page last updated: 2024-08-23

staurosporine and ruboxistaurin

staurosporine has been researched along with ruboxistaurin in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Baevsky, M; Ballas, LM; Faul, MM; Gillig, JR; Gonzalez, CM; Hall, SE; Heath, WF; Jirousek, MR; McDonald, JH; Melikian-Badalian, A; Neel, DA; Rito, CJ; Singh, U; Stramm, LE; Winneroski, LL1
Atteridge, CE; Azimioara, MD; Benedetti, MG; Biggs, WH; Carter, TA; Ciceri, P; Edeen, PT; Fabian, MA; Floyd, M; Ford, JM; Galvin, M; Gerlach, JL; Grotzfeld, RM; Herrgard, S; Insko, DE; Insko, MA; Lai, AG; Lélias, JM; Lockhart, DJ; Mehta, SA; Milanov, ZV; Patel, HK; Treiber, DK; Velasco, AM; Wodicka, LM; Zarrinkar, PP1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Gallant, P; Herrgard, S; Hunt, JP; Karaman, MW; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Treiber, DK; Wodicka, LM; Zarrinkar, PP1
Russu, WA; Shallal, HM1
Ciceri, P; Davis, MI; Herrgard, S; Hocker, M; Hunt, JP; Pallares, G; Treiber, DK; Wodicka, LM; Zarrinkar, PP1
Berger, BT; Chaikuad, A; Drápela, S; Knapp, S; Maier, L; Němec, V; Paruch, K; Souček, K1
Bertorello, AM; Efendiev, R; Pedemonte, CH1

Other Studies

8 other study(ies) available for staurosporine and ruboxistaurin

ArticleYear
(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Humans; Indoles; Isoenzymes; Maleimides; Molecular Sequence Data; Molecular Structure; Plasminogen Activators; Protein Kinase C; Protein Kinase C beta

1996
A small molecule-kinase interaction map for clinical kinase inhibitors.
    Nature biotechnology, 2005, Volume: 23, Issue:3

    Topics: Benzamides; Drug Design; Escherichia coli; Escherichia coli Proteins; Imatinib Mesylate; Microchemistry; Pharmaceutical Preparations; Piperazines; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Pyrimidines

2005
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
A quantitative analysis of kinase inhibitor selectivity.
    Nature biotechnology, 2008, Volume: 26, Issue:1

    Topics: Binding Sites; Enzyme Activation; Humans; Phosphotransferases; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Proteome; Quantitative Structure-Activity Relationship

2008
Discovery, synthesis, and investigation of the antitumor activity of novel piperazinylpyrimidine derivatives.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Pyrimidines; Stereoisomerism; Structure-Activity Relationship

2011
Comprehensive analysis of kinase inhibitor selectivity.
    Nature biotechnology, 2011, Oct-30, Volume: 29, Issue:11

    Topics: Catalysis; Drug Design; Enzyme Stability; High-Throughput Screening Assays; Humans; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Proteomics; Signal Transduction; Substrate Specificity

2011
Highly selective inhibitors of protein kinases CLK and HIPK with the furo[3,2-b]pyridine core.
    European journal of medicinal chemistry, 2021, Apr-05, Volume: 215

    Topics: Animals; Carrier Proteins; Crystallography, X-Ray; Furans; Humans; MCF-7 Cells; Mice; Molecular Structure; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Structure-Activity Relationship

2021
PKC-beta and PKC-zeta mediate opposing effects on proximal tubule Na+,K+-ATPase activity.
    FEBS letters, 1999, Jul-30, Volume: 456, Issue:1

    Topics: Animals; Dopamine; Enzyme Inhibitors; Indoles; Isoenzymes; Kidney Tubules, Proximal; Maleimides; Opossums; Peptides; Protein Kinase C; Protein Kinase C beta; Rubidium; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate

1999