Page last updated: 2024-08-23

staurosporine and rottlerin

staurosporine has been researched along with rottlerin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.00)18.2507
2000's14 (70.00)29.6817
2010's3 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goekjian, P; Jochum, A; Jung, M; Kunick, C; Marshall, B; Meier, R; Saunders, L; Sippl, W; Trapp, J; Verdin, E1
Gschwendt, M; Kittstein, W; Marks, F1
Cole, T; Liedtke, CM1
Bheekha-Escura, R; Chance, SR; Langdon, JM; MacDonald, SM; MacGlashan, DW1
Alexander, SR; Kishimoto, TK; Walcheck, B1
Kilpatrick, LE; Korchak, HM; Rossi, MW; Song, YH1
Chen, JS; Song, JG1
Fong, WF; Lam, W; Leung, CH; Wong, NS; Yang, MS; Zhuang, WJ1
Lange, Y; Steck, TL; Ye, J1
Goff, SP; Ishii, T; Li, B; Soh, JW; Tan, CP1
Akita, Y; Gutierrez-Hartmann, A; Manning, N; Pickett, CA1
Bernhardt, R; Bureik, M; Zeeh, A1
Bussmeyer, I; Hartmann, D; Hundhausen, C; Kallen, KJ; Ludwig, A; Matthews, V; Rose-John, S; Sadowski, T; Saftig, P; Schuster, B; Schütze, S1
Chain, BM; Cho, JY; Katz, DR1
Ansari, A; Dorovkov, MV; Ryazanov, AG; Ryazanova, LV1
Bowden, GT; Zhang, Y; Zhu, M1
Lin, MW; Wang, YJ; Wu, SN1
Chen, MS; Chiu, IM; Chung, YF; Hsu, YC; Kao, CY1
Chieng, YC; Hoon, LS; Hsum, YW; Mooi, LY; Soo, KK; Yew, WT1
Kim, BJ; Kim, JN1

Other Studies

20 other study(ies) available for staurosporine and rottlerin

ArticleYear
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition.
    Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25

    Topics: Acetylation; Adenosine; Binding Sites; Cell Line, Tumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Mimicry; Protein Kinase Inhibitors; Sirtuins; Structure-Activity Relationship; Tubulin

2006
Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor rottlerin and relative insensitivity towards staurosporine.
    FEBS letters, 1994, Jan-24, Volume: 338, Issue:1

    Topics: Acetophenones; Alkaloids; Animals; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Mice; Phosphorylation; Protein Kinase Inhibitors; Staurosporine

1994
Antisense oligodeoxynucleotide to PKC-delta blocks alpha 1-adrenergic activation of Na-K-2Cl cotransport.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Acetophenones; Base Sequence; Benzopyrans; Biological Transport; Bumetanide; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cells, Cultured; Chlorides; Enzyme Inhibitors; Humans; Isoenzymes; Kinetics; Methoxamine; Mucous Membrane; Naphthalenes; Nystatin; Oligonucleotides, Antisense; Protein Kinase C; Protein Kinase C-delta; Receptors, Adrenergic, alpha-1; RNA, Messenger; Sodium-Potassium-Chloride Symporters; Staurosporine; Trachea; Transcription, Genetic

1997
Pharmacologic regulation of histamine release by the human recombinant histamine-releasing factor.
    The Journal of allergy and clinical immunology, 1999, Volume: 103, Issue:5 Pt 1

    Topics: Acetophenones; Antibodies, Anti-Idiotypic; Basophils; Benzopyrans; Biomarkers, Tumor; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Enzyme Inhibitors; Histamine Release; Humans; Immunoglobulin E; Indoles; Lymphokines; Pertussis Toxin; Protein Kinase C; Recombinant Proteins; Staurosporine; Tumor Protein, Translationally-Controlled 1; Virulence Factors, Bordetella

1999
Effects of selective protein kinase C inhibitors on the proteolytic down-regulation of L-selectin from chemoattractant-activated neutrophils.
    Journal of leukocyte biology, 2000, Volume: 67, Issue:3

    Topics: Acetophenones; Antigens, CD; Benzopyrans; Cells, Cultured; Chemotactic Factors; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Dipeptides; Down-Regulation; Humans; Hydroxamic Acids; L-Selectin; Metalloendopeptidases; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Neutrophil Activation; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate

2000
Serine phosphorylation of p60 tumor necrosis factor receptor by PKC-delta in TNF-alpha-activated neutrophils.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:6

    Topics: Acetophenones; Benzopyrans; Down-Regulation; Enzyme Inhibitors; Humans; Isoenzymes; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Receptors, Tumor Necrosis Factor; Serine; Signal Transduction; Staurosporine; Tumor Necrosis Factor-alpha

2000
Bradykinin induces protein kinase C-dependent activation of phospholipase D in A-431 cells.
    IUBMB life, 2001, Volume: 51, Issue:1

    Topics: Acetophenones; Benzopyrans; Bradykinin; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Immunoblotting; Indoles; Isoenzymes; Kinetics; Maleimides; Phospholipase D; Phospholipids; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2001
PKCdelta-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF.
    Biochemical and biophysical research communications, 2001, Jul-13, Volume: 285, Issue:2

    Topics: Acetophenones; Benzopyrans; Cell Division; Cycloheximide; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; GADD45 Proteins; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Kinetics; Leupeptins; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Proteins; Pyridines; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ubiquitins

2001
Effect of protein kinase C on endoplasmic reticulum cholesterol.
    Biochemical and biophysical research communications, 2002, Jan-11, Volume: 290, Issue:1

    Topics: Acetophenones; Benzopyrans; Bryostatins; Calcium; Cell Membrane; Cells, Cultured; Cholesterol; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Enzyme Inhibitors; Fibroblasts; Humans; Lactones; Macrolides; Mitogens; Naphthalenes; Protein Isoforms; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate

2002
Pathways of induction of peroxiredoxin I expression in osteoblasts: roles of p38 mitogen-activated protein kinase and protein kinase C.
    The Journal of biological chemistry, 2002, Apr-05, Volume: 277, Issue:14

    Topics: 3T3 Cells; Acetophenones; Animals; Arsenates; Benzopyrans; Blotting, Northern; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Hydrogen Peroxide; Isoenzymes; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Peroxidases; Peroxiredoxins; Protein Binding; Protein Biosynthesis; Protein Kinase C; Protein Kinase C-delta; Protein Structure, Tertiary; RNA, Messenger; Signal Transduction; Staurosporine; Time Factors; Transcription, Genetic

2002
Role of specific protein kinase C isozymes in mediating epidermal growth factor, thyrotropin-releasing hormone, and phorbol ester regulation of the rat prolactin promoter in GH4/GH4C1 pituitary cells.
    Molecular endocrinology (Baltimore, Md.), 2002, Volume: 16, Issue:12

    Topics: Acetophenones; Animals; Benzopyrans; Calcium; Carbazoles; Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression Regulation; Indoles; Isoenzymes; Maleimides; Naphthalenes; Phorbol Esters; Pituitary Gland; Prolactin; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Staurosporine; Thyrotropin-Releasing Hormone; Transcription, Genetic

2002
Modulation of steroid hydroxylase activity in stably transfected V79MZh11B1 and V79MZh11B2 cells by PKC and PKD inhibitors.
    Endocrine research, 2002, Volume: 28, Issue:4

    Topics: Acetophenones; Alkaloids; Benzophenanthridines; Benzopyrans; Carbazoles; Cell Line; Cortodoxone; Desoxycorticosterone; Enzyme Inhibitors; Hydroxylation; Indoles; Phenanthridines; Protein Kinase C; Staurosporine; Steroid Hydroxylases; Transfection

2002
Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE).
    The Journal of biological chemistry, 2003, Oct-03, Volume: 278, Issue:40

    Topics: Acetophenones; ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Alternative Splicing; Amyloid Precursor Protein Secretases; Animals; Benzopyrans; beta-Cyclodextrins; Blotting, Western; Cell Line; Cell Membrane; Ceramides; Cholesterol; COS Cells; Cyclodextrins; Dimerization; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Interleukin-6; Lipid Metabolism; Membrane Proteins; Metalloendopeptidases; Mice; Mice, Transgenic; Monocytes; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Receptors, Interleukin-6; Sphingomyelins; Staurosporine; Time Factors; Transfection

2003
Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells

2003
Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel.
    The Journal of biological chemistry, 2004, Jan-30, Volume: 279, Issue:5

    Topics: Acetophenones; Benzopyrans; Calcium; Calmodulin; Catalytic Domain; Cations; Chromatography, Gel; Cobalt; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Electrophysiology; Enzyme Inhibitors; Escherichia coli; HeLa Cells; Histones; Humans; Ion Channels; Ions; Kinetics; Magnesium; Membrane Proteins; Molecular Sequence Data; Myelin Basic Protein; Phosphoamino Acids; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Staurosporine; Threonine; Time Factors; TRPM Cation Channels; Zinc

2004
Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes.
    Cancer letters, 2006, Dec-08, Volume: 244, Issue:2

    Topics: Acetophenones; Anthracenes; Antioxidants; Benzopyrans; Cells, Cultured; Enzyme Inhibitors; Green Fluorescent Proteins; Humans; Hydroquinones; Imidazoles; JNK Mitogen-Activated Protein Kinases; Keratinocytes; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Response Elements; Rhodamines; Signal Transduction; Staurosporine; Ultraviolet Rays

2006
Potent stimulation of large-conductance Ca2+-activated K+ channels by rottlerin, an inhibitor of protein kinase C-delta, in pituitary tumor (GH3) cells and in cortical neuronal (HCN-1A) cells.
    Journal of cellular physiology, 2007, Volume: 210, Issue:3

    Topics: Acetophenones; Action Potentials; Adenoma; Animals; Benzopyrans; Carcinogens; Cell Line; Cell Line, Tumor; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Neurons; Pituitary Neoplasms; Potassium Channels; Potassium Channels, Calcium-Activated; Protein Kinase C-delta; Rats; Staurosporine; Tetradecanoylphorbol Acetate

2007
Ciliogenic RFX transcription factors regulate FGF1 gene promoter.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:7

    Topics: Acetophenones; Benzopyrans; Cell Line, Tumor; Cell Nucleus; DNA-Binding Proteins; Fibroblast Growth Factor 1; Genes, Reporter; Glioblastoma; Green Fluorescent Proteins; Humans; Promoter Regions, Genetic; Protein Kinase C; Regulatory Factor X Transcription Factors; Regulatory Factor X1; RNA Interference; RNA, Small Interfering; Staurosporine; Transcription Factors; Transcription, Genetic

2012
Suppressive effect of maslinic acid on PMA-induced protein kinase C in human B-lymphoblastoid cells.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Anticarcinogenic Agents; Benzopyrans; Cells, Cultured; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Isoenzymes; Oleanolic Acid; Precursor Cells, B-Lymphoid; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid

2012
The Mechanism of Action of Ghrelin and Motilin in the Pacemaker Potentials of Interstitial Cells of Cajal from the Murine Small Intestine.
    Molecules and cells, 2019, Jun-30, Volume: 42, Issue:6

    Topics: Acetophenones; Amides; Animals; Benzopyrans; Boron Compounds; Calcium; Carbazoles; Gastrointestinal Motility; Ghrelin; Inositol 1,4,5-Trisphosphate Receptors; Interstitial Cells of Cajal; Intestine, Small; Macrocyclic Compounds; Membrane Potentials; Mice; Mice, Inbred ICR; Motilin; Oligopeptides; Oxazoles; Protein Kinase C; Pyridines; Receptors, Ghrelin; rho-Associated Kinases; Signal Transduction; Staurosporine; Thapsigargin

2019