staurosporine has been researched along with rifampin in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Langsley, G; Lizundia, R; Ralph, SA; Werling, D | 1 |
| Franzblau, SG; Guo, S; Kozikowski, AP; Mesecar, AD; Mo, S; Orjala, J; Pegan, SD; Tipparaju, SK; Wan, B | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bloomer, WD; Kaiser, M; Papadopoulou, MV; Rosenzweig, HS | 1 |
| Bloomer, WD; Papadopoulou, MV; Rosenzweig, HS | 1 |
| Ansari, I; Jadhav, H; Patel, H; Pawara, R; Surana, S | 1 |
| Bermudez, LE; Danelishvili, L; Li, YJ; McGarvey, J | 1 |
| Dutreix, C; Lorenzo, S; Munarini, F; Roesel, J; Wang, Y | 1 |
| Dutreix, C; Lorenzo, S; Wang, Y | 1 |
| Chun, DY; Dutreix, C; Einolf, HJ; Gu, H; He, H; Ouatas, T; Rebello, S; Wang, L | 1 |
2 trial(s) available for staurosporine and rifampin
| Article | Year |
|---|---|
Investigation into CYP3A4-mediated drug-drug interactions on midostaurin in healthy volunteers.
Topics: Adult; Antineoplastic Agents; Chromatography, Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Administration Schedule; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Female; Humans; Ketoconazole; Male; Midazolam; Middle Aged; Rifampin; Staurosporine; Tandem Mass Spectrometry; Young Adult | 2013 |
Comparison of two endogenous biomarkers of CYP3A4 activity in a drug-drug interaction study between midostaurin and rifampicin.
Topics: Adult; Biomarkers; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Drug Interactions; Female; Humans; Hydrocortisone; Hydroxycholesterols; Male; Middle Aged; Protein Kinase Inhibitors; Rifampin; Staurosporine; Young Adult | 2014 |
10 other study(ies) available for staurosporine and rifampin
| Article | Year |
|---|---|
Theileria apicoplast as a target for chemotherapy.
Topics: Animals; Antiprotozoal Agents; Cattle; Drug Delivery Systems; Inhibitory Concentration 50; Models, Biological; Plastids; Theileria; Theileriasis | 2009 |
Natural product leads for drug discovery: isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3-a]carbazole based ligands as antibacterial agents.
Topics: Anti-Bacterial Agents; Bacillus anthracis; Biological Products; Carbazoles; Drug Discovery; Drug Evaluation, Preclinical; Ligands; Microbial Sensitivity Tests; Mycobacterium tuberculosis | 2009 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
The antitrypanosomal and antitubercular activity of some nitro(triazole/imidazole)-based aromatic amines.
Topics: Amines; Antitubercular Agents; Dose-Response Relationship, Drug; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Parasitic Sensitivity Tests; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2017 |
The antitubercular activity of various nitro(triazole/imidazole)-based compounds.
Topics: Animals; Antitubercular Agents; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Humans; Imidazoles; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Structure-Activity Relationship; Triazoles | 2017 |
Pyridine and nitro-phenyl linked 1,3,4-thiadiazoles as MDR-TB inhibitors.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitrophenols; Pyridines; Structure-Activity Relationship; Thiadiazoles; Tuberculosis, Multidrug-Resistant; Vero Cells | 2019 |
Mycobacterium tuberculosis infection causes different levels of apoptosis and necrosis in human macrophages and alveolar epithelial cells.
Topics: Antibiotics, Antitubercular; Apoptosis; bcl-Associated Death Protein; Carrier Proteins; Cell Line; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Macrophages; Mycobacterium tuberculosis; Necrosis; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-bcl-2; Pulmonary Alveoli; Rifampin; Staurosporine | 2003 |
Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of Midostaurin.
Topics: Adult; Biomarkers; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Hydroxycholesterols; Ketoconazole; Male; Midazolam; Middle Aged; Models, Biological; Rifampin; Staurosporine; Young Adult | 2018 |