staurosporine has been researched along with quercetin in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 10 (38.46) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 5 (19.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, CJ; Geahlen, RL | 1 |
| Habtemariam, S | 1 |
| Hawkins, PT; Pacold, ME; Perisic, O; Stephens, L; Walker, EH; Williams, RL; Wymann, MP | 1 |
| Bain, J; Battistutta, R; de Moliner, E; Elliott, M; Fabbro, D; Furet, P; Meggio, F; Pagano, MA; Pinna, LA; Ruzzene, M; Sarno, S; Schoepfer, J; Zanotti, G | 1 |
| Bullock, AN; Debreczeni, JE; Fedorov, OY; Knapp, S; Marsden, BD; Nelson, A | 1 |
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Cywin, CL; Farmer, BT; Hickey, E; Homon, C; Jakes, S; Kashem, MA; Lee, G; Leonard, S; Li, J; Magboo, R; Mao, W; Morwick, T; Pack, E; Peng, C; Prokopowicz, A; Qian, K; Wang, L; Welzel, M; Wolak, J | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aly, AH; Debbab, A; Diederich, M; El Amrani, M; Feger, D; Gaigneaux, A; Lai, D; Lin, W; Proksch, P; Schnekenburger, M; Seidel, C; Siems, K | 1 |
| Antonelli, A; Botta, L; Coviello, V; Da Settimo, F; Fallahi, P; Ferrari, SM; Hsing-Pang, H; Ke, YY; La Motta, C; La Pietra, V; Marinelli, L; Moriconi, A; Novellino, E; Quattrini, L; Sartini, S | 1 |
| Aubourg, A; Ollivier-Bousquet, M | 1 |
| Boscá, L; Díaz-Guerra, MJ; Junco, M | 1 |
| Doppler, W; Grunicke, HH; Hofmann, J; Jakob, A; Maly, K; Posch, L; Uberall, F | 1 |
| Duarte, J; Jiménez, J; Pérez-Vizcaíno, F; Tamargo, J; Zarzuelo, A | 1 |
| Barret, JM; Boutin, JA; Ernould, AP; Ferry, G; Genton, A | 1 |
| Bayat-Sarmadi, M; Houdebine, LM | 1 |
| Furuya, R; Hishida, A; Kumagai, H | 1 |
| Grosman, N | 1 |
| Li, J; Peet, GW | 1 |
| Boyle, SM; Liu, F; Omiecinski, CJ; Sidhu, JS | 1 |
| Parekh, AB; Straube, S | 1 |
| Arai, H; Fijimoto, M; Nagasaka, Y; Nakamura, K | 1 |
| Bacon, KB; Fuchikami, K; Gantner, F; Reinemer, P; Sagara, A; Satoh, T; Togame, H | 1 |
| Avila, CM; Barreiro, EJ; Fraga, CA; Romeiro, NC; Sant'Anna, CM | 1 |
| Agalakova, NI; Gusev, GP | 1 |
1 review(s) available for staurosporine and quercetin
| Article | Year |
|---|---|
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases | 1992 |
25 other study(ies) available for staurosporine and quercetin
| Article | Year |
|---|---|
Flavonoids as inhibitors or enhancers of the cytotoxicity of tumor necrosis factor-alpha in L-929 tumor cells.
Topics: Animals; Apoptosis; Drug Synergism; Flavonoids; Mice; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Androstadienes; Animals; Binding Sites; Brain; Cattle; Chromones; Crystallography, X-Ray; Enzyme Inhibitors; Flavonoids; Humans; Models, Molecular; Molecular Sequence Data; Morpholines; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Conformation; Protein Structure, Secondary; Quercetin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Staurosporine; Wortmannin | 2000 |
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).
Topics: Acetates; Animals; Casein Kinase II; Cell Line; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Jurkat Cells; Molecular Structure; Plant Proteins; Protein Serine-Threonine Kinases; Protein Structure, Quaternary; Quinazolines; Rats; Zea mays | 2003 |
Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.
Topics: Antineoplastic Agents; Crystallization; Crystallography, X-Ray; Flavonoids; Humans; Imidazoles; Indoles; Maleimides; Models, Molecular; Molecular Structure; Moloney murine leukemia virus; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-pim-1; Proviruses; Pyrazoles; Pyridazines; Pyrimidines; Structure-Activity Relationship | 2005 |
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode.
Topics: Azepines; Binding Sites; Casein Kinase II; Crystallography, X-Ray; Models, Molecular; Phenylpropionates; Proto-Oncogene Proteins c-pim-1; Stereoisomerism; Structure-Activity Relationship | 2009 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum.
Topics: Ascomycota; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Humans; Inhibitory Concentration 50; Mentha; Molecular Structure; Morocco; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Polyketides; Protein Kinase Inhibitors; Protein Kinases; Structure-Activity Relationship | 2014 |
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors.
Topics: Antineoplastic Agents; Carcinoma, Neuroendocrine; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Structure-Activity Relationship; Thyroid Gland; Thyroid Neoplasms | 2018 |
The possible involvement of protein kinase C(s) and inositol phosphate metabolism in the basal but not in the prolactin stimulated casein release by the lactating rabbit mammary epithelial cell.
Topics: Alkaloids; Animals; Caseins; Diglycerides; Enzyme Activation; Epithelium; Female; Inositol Phosphates; Lactation; Mammary Glands, Animal; Prolactin; Protein Kinase C; Quercetin; Rabbits; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Substrate-dependent inhibition of protein kinase C by specific inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Brain; Chromatography, Affinity; Chromatography, Ion Exchange; Gossypol; Homeostasis; Isoquinolines; Kinetics; Ligands; Piperazines; Protein Kinase C; Quercetin; Rats; Sphingosine; Staurosporine; Substrate Specificity | 1990 |
Enhancement of the antiproliferative effect of cis-diamminedichloroplatinum(II) and nitrogen mustard by inhibitors of protein kinase C.
Topics: Alkaloids; Animals; Cell Division; Cisplatin; Drug Synergism; Mechlorethamine; Protein Kinase C; Quercetin; Rats; Staurosporine; Tamoxifen; Tetradecanoylphorbol Acetate | 1988 |
Inhibitory effects of quercetin and staurosporine on phasic contractions in rat vascular smooth muscle.
Topics: Alkaloids; Animals; Aorta; Caffeine; Calcium; Dose-Response Relationship, Drug; Female; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Protein Kinase C; Quercetin; Rats; Rats, Wistar; Serotonin; Sodium; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Integrated system for the screening of the specificity of protein kinase inhibitors.
Topics: Alkaloids; Animals; Carrier Proteins; Enzyme Inhibitors; Humans; Hydroquinones; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Kinetics; Mice; Peptides; Protein Kinase Inhibitors; Protein Kinases; Quercetin; Rats; Staurosporine; Suramin | 1993 |
Effect of various protein kinase inhibitors on the induction of milk protein gene expression by prolactin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenine; Alkaloids; Animals; Cells, Cultured; Epithelial Cells; Epithelium; Female; Gene Expression Regulation; Genistein; Isoflavones; Isoquinolines; Mammary Glands, Animal; Milk Proteins; Phenols; Phenylacetates; Piperazines; Polymyxin B; Pregnancy; Prolactin; Protein Kinase Inhibitors; Quercetin; Rabbits; Sphingosine; Staurosporine; Succinates | 1993 |
Acquired resistance to rechallenge injury with uranyl acetate in LLC-PK1 cells.
Topics: Animals; Enzyme Inhibitors; Hot Temperature; L-Lactate Dehydrogenase; LLC-PK1 Cells; Organometallic Compounds; Proteins; Quercetin; Staurosporine; Swine; Uranium | 1997 |
Influence of probes for calcium-calmodulin and protein kinase C signalling on the plasma membrane Ca2+-ATPase activity of rat synaptosomes and leukocyte membranes.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Calmodulin; Cell Membrane; Enzyme Inhibitors; Gallic Acid; Imidazoles; Leukocytes; Male; Phosphodiesterase Inhibitors; Phospholipid Ethers; Phosphorylcholine; Protein Kinase C; Quercetin; Rats; Rats, Wistar; Signal Transduction; Sphingosine; Staurosporine; Synaptosomes | 1998 |
IkappaB kinases alpha and beta show a random sequential kinetic mechanism and are inhibited by staurosporine and quercetin.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Enzyme Inhibitors; I-kappa B Kinase; Isoflavones; Kinetics; Molecular Structure; NF-kappa B; Peptide Fragments; Phosphorylation; Protein Serine-Threonine Kinases; Quercetin; Staurosporine; Transcriptional Activation | 1999 |
PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes.
Topics: Androstadienes; Animals; Cells, Cultured; Cytochrome P-450 CYP2E1; Drug Interactions; Enzyme Inhibitors; Gene Expression; Hepatocytes; Insulin; Insulin Antagonists; Male; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quercetin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serum Albumin; Staurosporine; Transcription Factor AP-1; Wortmannin | 2001 |
Effects of phosphatidylinositol kinase inhibitors on the activation of the store-operated calcium current ICRAC in RBL-1 cells.
Topics: 1-Phosphatidylinositol 4-Kinase; Androstadienes; Animals; Calcium; Chromones; Enzyme Inhibitors; Leukemia, Basophilic, Acute; Morpholines; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Quercetin; Rats; Staurosporine; Tumor Cells, Cultured; Wortmannin | 2001 |
Inhibition of heat-induced phosphorylation of stathmin by the bioflavonoid quercetin.
Topics: Flavonoids; Hot Temperature; Humans; Immunoblotting; Jurkat Cells; Microtubule Proteins; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Quercetin; Serine; Stathmin; Staurosporine | 2002 |
A versatile high-throughput screen for inhibitors of lipid kinase activity: development of an immobilized phospholipid plate assay for phosphoinositide 3-kinase gamma.
Topics: Adenosine Triphosphate; Androstadienes; Biological Assay; Class Ib Phosphatidylinositol 3-Kinase; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Isoenzymes; Lipid Metabolism; Microchemistry; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphoinositide-3 Kinase Inhibitors; Phospholipids; Phosphorus Radioisotopes; Quercetin; Recombinant Proteins; Staurosporine; Wortmannin | 2002 |
Structural insights into IKKbeta inhibition by natural products staurosporine and quercetin.
Topics: Biological Products; Drug Design; I-kappa B Kinase; Quercetin; Staurosporine; Structure-Activity Relationship | 2009 |
Regulation of K-Cl cotransport in erythrocytes of frog Rana temporaria by commonly used protein kinase and protein phosphatase inhibitors.
Topics: Animals; Benzophenanthridines; Biological Transport; Enzyme Inhibitors; Erythrocytes; Fluorides; Genistein; K Cl- Cotransporters; Okadaic Acid; Ouabain; Phosphoprotein Phosphatases; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quercetin; Rana temporaria; Staurosporine; Symporters; Tyrphostins | 2010 |