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staurosporine and phorbol-12,13-didecanoate

staurosporine has been researched along with phorbol-12,13-didecanoate in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's30 (96.77)18.2507
2000's1 (3.23)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Heinrich, PC; Müllberg, J; Rose-John, S; Schooltink, H; Stoyan, T1
Endo, Y; Furuya, S; Matsui, Y; Nozawa, S; Oba, M; Suzuki, S1
Endo, Y; Furuya, S; Nozawa, S; Oba, M; Suzuki, S1
Alkhalaf, B; Gong, Y; Murphy, LC; Murphy, LJ1
Feldman, D; Krishnan, AV1
Koch, B; Lutz-Bucher, B1
Arner, EC; Pratta, MA1
Crane, DL; Elliott, MS1
Marshall, TM; Peters-Golden, M; Sporn, PH1
Ikebuchi, H; Saito, Y; Suzuki, K; Suzuki, S; Terao, T1
Pitt, BR; Weng, W1
Betz, H; Sato, K; Schloss, P1
de Prost, D; Hakim, J; Khechai, F; Ollivier, V; Ramani, M; Ternisien, C; Vu, T1
Crevel, H; Marthan, R; Rossetti, M; Savineau, JP1
Fujiwara, R; Miyabo, S; Nakai, T; Shimada, A; Tamai, T1
Dooley, NP; Noble, PG; Yong, VW1
Brown, HE; Kow, LM; Pfaff, DW1
Araki, M; Inaba, H; Numai, T1
Black, SC; Chi, L; Fagbemi, SO; Friedrichs, GS; Lucchesi, BR1
LaPointe, MC; Sitkins, JR1
Behue, N; Brule, G; Charpentier, G; Fournier, F; Marlot, D1
Tsien, RW; Yang, J1
Finnegan, SG; Koenig, E; Lemmon, VP1
Kozawa, O; Miwa, M; Tokuda, H1
Bennardini, F; Pinna, G; Pintus, G; Tadolini, B; Vaona, I; Ventura, C1
Hsieh, JT; Luo, SF; Ong, R; Tsao, HL; Yang, CM1
Crosson, CE; Ganel, R1
Amorena, C; Castro, AF; Müller, A; Ottaviano, G; Taquini, AC; Tellez-Iñon, MT1
Lee, FJ; Liu, F; Man, HY; McConkey, F; Niznik, HB; Pristupa, ZB; Wang, YT1
Behrens, MM; Choi, DW; Gwag, BJ; Koh, JY; Strasser, U1
Tai, HH; Tong, M1

Other Studies

31 other study(ies) available for staurosporine and phorbol-12,13-didecanoate

ArticleYear
Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor.
    Biochemical and biophysical research communications, 1992, Dec-15, Volume: 189, Issue:2

    Topics: Alkaloids; Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Humans; Interleukin-6; Kinetics; Liver Neoplasms; Macromolecular Substances; Phorbol Esters; Protein Kinase C; Receptors, Immunologic; Receptors, Interleukin-6; Recombinant Proteins; Staurosporine; Transfection; Tumor Cells, Cultured

1992
Protein phosphorylation regulates the mouse sperm acrosome reaction induced by the zona pellucida.
    Journal of assisted reproduction and genetics, 1992, Volume: 9, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acrosome; Alkaloids; Animals; Diglycerides; Ethers, Cyclic; Exocytosis; Female; Genistein; Isoflavones; Isoquinolines; Male; Membrane Fusion; Mice; Okadaic Acid; Phorbol Esters; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Signal Transduction; Sperm-Ovum Interactions; Staurosporine; Tetradecanoylphorbol Acetate; Zona Pellucida

1992
Effects of modulators of protein kinases and phosphatases on mouse sperm capacitation.
    Journal of assisted reproduction and genetics, 1992, Volume: 9, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bucladesine; Chlortetracycline; Dibutyryl Cyclic GMP; Diglycerides; Ethers, Cyclic; Fluorescence; Genistein; Isoflavones; Isoquinolines; Male; Mice; Okadaic Acid; Peptide Fragments; Phorbol Esters; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Sperm Capacitation; Staurosporine; Tetradecanoylphorbol Acetate

1992
Differential effects of phorbol esters on proliferation and calcyclin expression in human endometrial carcinoma cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1992, Volume: 3, Issue:11

    Topics: Adenocarcinoma; Alkaloids; Calcimycin; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Division; Cycloheximide; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; S100 Calcium Binding Protein A6; S100 Proteins; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Uterine Neoplasms

1992
Activation of protein kinase-C inhibits vitamin D receptor gene expression.
    Molecular endocrinology (Baltimore, Md.), 1991, Volume: 5, Issue:4

    Topics: Alkaloids; Animals; Blotting, Northern; Blotting, Southern; Calcimycin; Cell Division; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Down-Regulation; Fibroblast Growth Factor 2; Gene Expression Regulation, Enzymologic; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate

1991
Inhibition of protein kinase C activity in cultured pituitary cells attenuates both cyclic AMP-independent and -dependent secretion of ACTH.
    Molecular and cellular endocrinology, 1991, Volume: 77, Issue:1-3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Alkaloids; Animals; Arginine Vasopressin; Carcinogens; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Kinetics; Male; Phorbol Esters; Pituitary Gland, Anterior; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate; Veratridine

1991
Modulation of interleukin-1-induced alterations in cartilage proteoglycan metabolism by activation of protein kinase C.
    Arthritis and rheumatism, 1991, Volume: 34, Issue:8

    Topics: Alkaloids; Animals; Carcinogens; Cartilage; Cattle; Dinoprostone; Diterpenes; Down-Regulation; Enzyme Activation; Interleukin-1; Organ Culture Techniques; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Proteoglycans; Staurosporine; Terpenes

1991
Protein kinase C modulation of queuine uptake in cultured human fibroblasts.
    Biochemical and biophysical research communications, 1990, Aug-31, Volume: 171, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Calcimycin; Cells, Cultured; Diglycerides; Enzyme Activation; Fibroblasts; Growth Substances; Guanine; Humans; In Vitro Techniques; Isoquinolines; Male; Phorbol Esters; Phosphatidylserines; Piperazines; Protein Kinase C; Sphingosine; Staurosporine

1990
Differential dependence on protein kinase C of arachidonic acid metabolism stimulated by hydrogen peroxide and by zymosan in the alveolar macrophage.
    Biochimica et biophysica acta, 1990, Nov-12, Volume: 1047, Issue:2

    Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Eicosanoids; Female; Hydrogen Peroxide; Macrophages; Phorbol Esters; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan

1990
Human growth hormone-stimulated growth of human cultured lymphocytes (IM-9) and its inhibition by phorbol diesters through down-regulation of the hormone receptors. Possible involvement of phosphorylation of a 55,000 molecular weight protein associated wi
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Alkaloids; Blood; Cell Division; Cell Line; Down-Regulation; Enzyme Activation; Growth Hormone; Humans; Kinetics; Lymphocytes; Molecular Weight; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphoproteins; Phosphorylation; Protein Kinase C; Receptors, Somatotropin; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate

1990
Activation of protein kinase C inhibits extraction of serotonin by perfused rat lung in situ.
    The American journal of physiology, 1990, Volume: 258, Issue:6 Pt 1

    Topics: Alkaloids; Animals; Carcinogens; Diterpenes; Enzyme Activation; Kinetics; Lung; Male; Papaverine; Perfusion; Phorbol Esters; Protein Kinase C; Pulmonary Circulation; Rats; Rats, Inbred Strains; Serotonin; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate

1990
The recombinant GABA transporter GAT1 is downregulated upon activation of protein kinase C.
    FEBS letters, 1995, Nov-13, Volume: 375, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Biological Transport; Carrier Proteins; Cell Line; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Isoquinolines; Kidney; Kinetics; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Phorbol Esters; Piperazines; Protein Kinase C; Rats; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection

1995
Endotoxin-induced tissue factor in human monocytes is dependent upon protein kinase C activation.
    Thrombosis and haemostasis, 1993, Nov-15, Volume: 70, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Endotoxins; Enzyme Activation; Gene Expression Regulation; Humans; Isoquinolines; Monocytes; Naphthalenes; Naphthol AS D Esterase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Polycyclic Compounds; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thromboplastin

1993
Role of protein kinase C in nonsensitized and passively sensitized human isolated bronchial smooth muscle.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: Alkaloids; Allergens; Asthma; Bronchi; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Immunization, Passive; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Staurosporine; Time Factors; Verapamil

1995
Effects of insulin, insulin-like growth factor-I, and phorbol esters on neutral cholesteryl esterase activity in cultured rat vascular smooth muscle cells.
    The Journal of laboratory and clinical medicine, 1995, Volume: 126, Issue:3

    Topics: Alkaloids; Animals; Aorta; Carbazoles; Cells, Cultured; Cyclic AMP; Indoles; Insulin; Insulin-Like Growth Factor I; Male; Muscle, Smooth, Vascular; Phenylurea Compounds; Phorbol Esters; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Staurosporine; Sterol Esterase; Sterol O-Acyltransferase; Tetradecanoylphorbol Acetate

1995
Protein kinase C in cultured adult human oligodendrocytes: a potential role for isoform alpha as a mediator of process outgrowth.
    Journal of neuroscience research, 1994, Sep-01, Volume: 39, Issue:1

    Topics: Adult; Alkaloids; Animals; Base Sequence; Benzophenanthridines; Brain; Cells, Cultured; Diterpenes; Female; Humans; Isoenzymes; Molecular Sequence Data; Myelin Sheath; Nerve Tissue Proteins; Oligodendroglia; Phenanthridines; Phorbol Esters; Protein Kinase C; Rats; Rats, Wistar; Staurosporine

1994
Activation of protein kinase C in the hypothalamic ventromedial nucleus or the midbrain central gray facilitates lordosis.
    Brain research, 1994, Oct-17, Volume: 660, Issue:2

    Topics: Alkaloids; Animals; Cholesterol; Enzyme Activation; Estradiol; Female; Infusions, Parenteral; Male; Mesencephalon; Mifepristone; Ovariectomy; Phorbol Esters; Posture; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sexual Behavior, Animal; Staurosporine; Tetradecanoylphorbol Acetate; Ventromedial Hypothalamic Nucleus

1994
Modulation of protein kinase C alters hemodynamics and metabolism in the isolated liver in fed and fasted rats.
    Journal of hepatology, 1993, Volume: 19, Issue:3

    Topics: Alkaloids; Animals; Enzyme Activation; Fasting; Food; Hemodynamics; In Vitro Techniques; Liver; Liver Circulation; Male; Organ Size; Perfusion; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate

1993
Phorbol ester-induced ventricular fibrillation in the Langendorff-perfused rabbit heart: antagonism by staurosporine and glibenclamide.
    Journal of molecular and cellular cardiology, 1993, Volume: 25, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Diglycerides; Glyburide; Guanidines; Isoquinolines; Perfusion; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pinacidil; Piperazines; Protein Kinase C; Rabbits; Staurosporine; Ventricular Fibrillation

1993
Phorbol ester stimulates the synthesis and secretion of brain natriuretic peptide from neonatal rat ventricular cardiocytes: a comparison with the regulation of atrial natriuretic factor.
    Molecular endocrinology (Baltimore, Md.), 1993, Volume: 7, Issue:10

    Topics: Alkaloids; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Cultured; Dactinomycin; Heart Ventricles; Kinetics; Myocardium; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Phorbol Esters; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic

1993
Positive regulation by protein kinase C of slow Na current in Xenopus oocytes.
    Proceedings. Biological sciences, 1993, Oct-22, Volume: 254, Issue:1339

    Topics: Alkaloids; Animals; Diglycerides; Enzyme Activation; Female; Membrane Potentials; Oocytes; Phorbol Esters; Protein Kinase C; Sodium Channels; Staurosporine; Tamoxifen; Tetradecanoylphorbol Acetate; Tetrodotoxin; Xenopus laevis

1993
Enhancement of N- and L-type calcium channel currents by protein kinase C in frog sympathetic neurons.
    Neuron, 1993, Volume: 10, Issue:2

    Topics: Alkaloids; Animals; Barium; Calcium Channels; Electric Conductivity; Ganglia, Sympathetic; GTP-Binding Proteins; Kinetics; Neurons; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rana catesbeiana; Staurosporine

1993
Monoclonal antibody 8A2-induced retraction appears to be mediated by protein phosphorylation in goldfish retinal ganglion cell axons.
    Developmental biology, 1993, Volume: 156, Issue:1

    Topics: Alkaloids; Animals; Antibodies, Monoclonal; Axons; Calcium; Cyclic AMP; Ethers, Cyclic; Goldfish; Nerve Regeneration; Okadaic Acid; Organ Culture Techniques; Phorbol Esters; Phorbols; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Retinal Ganglion Cells; Staurosporine; Tetradecanoylphorbol Acetate

1993
Cross-talk between Ca2+ influx and phosphoinositide hydrolysis by extracellular adenosine triphosphate in rat PC12 pheochromocytoma cells.
    Endocrinology, 1993, Volume: 133, Issue:1

    Topics: Adenosine Triphosphate; Alkaloids; Animals; Calcium; Calcium Radioisotopes; Hydrolysis; Kinetics; Nifedipine; PC12 Cells; Pertussis Toxin; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1993
Phorbol ester regulation of opioid peptide gene expression in myocardial cells. Role of nuclear protein kinase.
    The Journal of biological chemistry, 1995, Dec-15, Volume: 270, Issue:50

    Topics: Alkaloids; Animals; Cell Nucleus; Cells, Cultured; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalins; Enzyme Inhibitors; Gene Expression; Heart Ventricles; Isoenzymes; Kinetics; Male; Myocardium; Phorbol Esters; Protein Kinase C; Protein Precursors; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic

1995
Inhibitory effect of phorbol ester on bradykinin-induced phosphoinositide hydrolysis and calcium mobilization in cultured canine tracheal smooth muscle cells.
    Cellular signalling, 1995, Volume: 7, Issue:6

    Topics: Alkaloids; Animals; Bradykinin; Calcium; Cells, Cultured; Dogs; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Female; Hydrolysis; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Muscle, Smooth; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Receptors, Bradykinin; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Trachea

1995
Modulation of human glutamate transporter activity by phorbol ester.
    Journal of neurochemistry, 1998, Volume: 70, Issue:3

    Topics: Amino Acid Transport System X-AG; Anti-Bacterial Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Carcinogens; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamates; Glutamic Acid; Humans; Kainic Acid; Kinetics; Phorbol Esters; Protein Kinase C; Retinoblastoma; Staurosporine; Tumor Cells, Cultured

1998
Extracellular ATP and bradykinin increase cGMP in vascular endothelial cells via activation of PKC.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Bradykinin; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Fetus; Kinetics; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phorbol Esters; Polyethylene Glycols; Protein Kinase C; Staurosporine; Swine; Tetradecanoylphorbol Acetate; Time Factors; Vasodilator Agents

1998
Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter.
    Synapse (New York, N.Y.), 1998, Volume: 30, Issue:1

    Topics: Animals; Carrier Proteins; Cell Line; Cloning, Molecular; Cocaine; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Phorbol Esters; Protein Kinase C; Recombinant Proteins; Spodoptera; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection

1998
Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase C: blockade of p38 mitogen-activated protein kinase.
    Neuroscience, 1999, Volume: 94, Issue:3

    Topics: Amyloid beta-Peptides; Animals; Brain-Derived Neurotrophic Factor; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Culture Media, Serum-Free; Cycloheximide; Enzyme Inhibitors; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Kinetics; Maleimides; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Neurons; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phorbol Esters; Protein Kinase C; Pyridines; Staurosporine; Tetradecanoylphorbol Acetate

1999
Dexamethasone inhibits the induction of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase by phorbol ester in human promonocytic U937 cells.
    Biochimica et biophysica acta, 2000, Jun-02, Volume: 1497, Issue:1

    Topics: Anti-Inflammatory Agents; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Hydroxyprostaglandin Dehydrogenases; Indoles; Maleimides; Mifepristone; Phorbol Esters; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; U937 Cells

2000