staurosporine and pd 98059

Topics: Animals; Antineoplastic Agents; Azepines; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Philippines; Phosphorylation; Porifera; Protein Serine-Threonine Kinases; Pyrroles; Structure-Activity Relationship; Tumor Cells, Cultured

Topics: Cell Death; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Humans; Ion Channel Gating; Mitogen-Activated Protein Kinase Kinases; Oxidative Stress; Phosphorylation; Piperazines; raf Kinases; ras Proteins; Sensitivity and Specificity; Signal Transduction; Voltage-Dependent Anion Channel 2

Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

Topics: Alkaloids; Benzophenanthridines; Butyrates; Butyric Acid; Calcitriol; Cell Adhesion; Cell Adhesion Molecules; Cell Differentiation; Cycloheximide; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Mitogen-Activated Protein Kinase Kinases; Osteopontin; Phenanthridines; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase Inhibitors; Recombinant Proteins; RNA, Messenger; Sialoglycoproteins; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tretinoin

Topics: Blotting, Northern; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Flavonoids; Gene Expression Regulation; Humans; Isoenzymes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Polymerase Chain Reaction; Protein Kinase C; Receptors, LDL; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

Topics: Androstadienes; Animals; Choline; Enzyme Inhibitors; Ethanolamine; Flavonoids; Glioma; Indoles; Phosphoinositide-3 Kinase Inhibitors; Phospholipase D; Polyenes; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Sirolimus; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin

Topics: Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Immunoglobulin G; Mitogen-Activated Protein Kinase 1; Monocytes; Naphthalenes; Phagocytosis; Phospholipases; Phosphorylation; Phosphotyrosine; Protein Kinase C; Receptors, IgG; Staurosporine

Topics: Androstadienes; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Genistein; Heart; Heart Ventricles; Insulin-Like Growth Factor I; Myocardium; Phosphorylation; Polyenes; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Signal Transduction; Sirolimus; Staurosporine; Wortmannin

Topics: Base Sequence; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Cyclic AMP Response Element-Binding Protein; DNA; Enzyme Inhibitors; Flavonoids; Gene Products, tat; Genes, Reporter; HIV-1; Humans; Jurkat Cells; Leukocytes, Mononuclear; Phosphorylation; Serine; Signal Transduction; Staurosporine; tat Gene Products, Human Immunodeficiency Virus; Transfection

Topics: Androstadienes; Antigens, CD; Cadherins; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Membrane Permeability; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Histocytochemistry; Humans; Indoles; Lymphokines; Membrane Proteins; Muscle, Smooth, Vascular; Nitriles; Occludin; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Serum Albumin; Staurosporine; Tyrphostins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin

Topics: 4-Aminopyridine; Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-Antagonists; Alkaloids; Animals; Benzophenanthridines; Bumetanide; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Enzyme Inhibitors; Flavonoids; In Vitro Techniques; Kinetics; Male; Myocardium; Phenanthridines; Phenylephrine; Potassium Channels; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters; Staurosporine; Timolol

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Apoptosis; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Enzyme Inhibitors; Flavanones; Flavonoids; Genistein; Hippocampus; Indole Alkaloids; Male; Microscopy, Electron; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neurons; Okadaic Acid; Organ Culture Techniques; Phosphoric Monoester Hydrolases; Propidium; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Staurosporine; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Dinoprostone; Enkephalins; Enzyme Inhibitors; Flavonoids; Imidazoles; Isoquinolines; Kinetics; Nimodipine; omega-Conotoxin GVIA; Peptides; Phosphorylation; Protein Precursors; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Sulfonamides; Transcription Factor AP-1; Transcription, Genetic

Topics: Adenosine Triphosphate; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Flavonoids; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Staurosporine

Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chemokine CXCL2; Cycloheximide; Down-Regulation; Enzyme Inhibitors; Flavonoids; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monokines; Neutrophils; p38 Mitogen-Activated Protein Kinases; Peritoneum; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine

Topics: Adenosine Triphosphate; Androstadienes; Animals; Apoptosis; Buthionine Sulfoximine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Flavonoids; Hypoglycemic Agents; Insulin; Insulin Antagonists; Insulin-Like Growth Factor I; Iron; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; N-Methylaspartate; Necrosis; Neocortex; Neurons; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorus Radioisotopes; Phosphorylation; Staurosporine; Wortmannin

Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Cell Line; Cytosol; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Flavonoids; Indoles; Isoenzymes; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Kinases; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Thionucleotides; Tritium; Uridine Triphosphate

Topics: Animals; Arsenites; Bumetanide; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Chlorides; Edetic Acid; Enzyme Inhibitors; Erythrocytes; Ferrets; Flavonoids; Genistein; Homeostasis; Imidazoles; In Vitro Techniques; Models, Biological; Potassium; Pyridines; Rubidium; Rubidium Radioisotopes; Sodium; Sodium-Potassium-Chloride Symporters; Staurosporine

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Embryonal; Cell Differentiation; Ciliary Neurotrophic Factor; Cytokines; DNA-Binding Proteins; Flavonoids; Genes, Reporter; Growth Inhibitors; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Mice; Nerve Tissue Proteins; Neurons; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Signal Transduction; STAT3 Transcription Factor; Staurosporine; Trans-Activators; Transcriptional Activation; Tumor Cells, Cultured; Tyrphostins

Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; Enzyme Inhibitors; Flavonoids; Indoles; Isoquinolines; Kinetics; Lysophosphatidylcholines; Myocardium; Nimodipine; Phospholipases A; Protein Kinase C; Rats; Staurosporine; Structure-Activity Relationship; Sulfonamides

Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium-Calmodulin-Dependent Protein Kinases; Flavonoids; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; K562 Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Naphthalenes; Phorbol Esters; Protein Kinase C; Protein Kinase C-alpha; Proto-Oncogene Proteins c-raf; Signal Transduction; Staurosporine; Tumor Cells, Cultured

Topics: Amidines; Animals; Benzylamines; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Line; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Drug Design; Enzyme Inhibitors; Flavonoids; Imidazoles; Indole Alkaloids; Isoquinolines; Lipopolysaccharides; Mice; Microglia; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Pyridines; Staurosporine; Sulfonamides

Topics: Amyloid beta-Peptides; Animals; Brain-Derived Neurotrophic Factor; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Culture Media, Serum-Free; Cycloheximide; Enzyme Inhibitors; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Kinetics; Maleimides; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Neurons; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phorbol Esters; Protein Kinase C; Pyridines; Staurosporine; Tetradecanoylphorbol Acetate

Topics: Animals; Antihypertensive Agents; Blotting, Northern; Carcinogens; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation, Enzymologic; Genistein; Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; Oligopeptides; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Phorbol Esters; Phosphodiesterase Inhibitors; Phosphorylation; Piperidines; Propranolol; Protein Kinase C; Pyridines; Pyrrolidinones; RNA, Messenger; Skull; Staurosporine

Topics: Animals; Aurintricarboxylic Acid; bcl-2-Associated X Protein; Cell Line; Cell Survival; Drug Resistance; Enzyme Activation; Flavonoids; Interleukin-3; Mice; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Staurosporine; Transfection

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Animals; Avoidance Learning; Carbazoles; Entorhinal Cortex; Enzyme Inhibitors; Flavonoids; Guanylate Cyclase; Hippocampus; Indoles; Inhibition, Psychological; Male; Memory; Memory, Short-Term; Phenols; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Sodium Chloride; Staurosporine

Topics: Adenosine Triphosphate; Animals; Calcium; Cell Division; DNA; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glioma; Indoles; Isoenzymes; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; ras Proteins; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Staurosporine; Tumor Cells, Cultured; Uridine Triphosphate; Virulence Factors, Bordetella

Topics: Androstadienes; Apoptosis; Carcinoma; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA, Antisense; Epidermal Growth Factor; ErbB Receptors; Esophageal Neoplasms; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; Staurosporine; Transfection; Tumor Cells, Cultured; Wortmannin

Topics: Bridged-Ring Compounds; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Fluorescent Antibody Technique; Gene Expression; Humans; I-kappa B Kinase; Imidazoles; Indoles; Intercellular Adhesion Molecule-1; Interleukin-1; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Naphthalenes; NF-kappaB-Inducing Kinase; Norbornanes; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Kinase C-alpha; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Thiocarbamates; Thiones; Tyrphostins

Topics: Animals; Blotting, Western; Carrier Proteins; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Lectins; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Rats; Receptors, Cell Surface; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; U937 Cells

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Vessels; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Genistein; In Vitro Techniques; Indoles; Kidney; Male; Maleimides; Mesentery; Norepinephrine; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Staurosporine; Tyrphostins; Vasoconstriction

Topics: Animals; Benzoquinones; Calcium; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Genistein; Humans; Lactams, Macrocyclic; Lipoproteins, LDL; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Muscle, Smooth, Vascular; Pertussis Toxin; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Pyrrolidinones; Quinones; ras Proteins; Rats; Rats, Sprague-Dawley; Rifabutin; Staurosporine; Virulence Factors, Bordetella

Topics: Carcinogens; Catalase; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Insulin Resistance; Mitogen-Activated Protein Kinases; Monocytes; Protein Kinase C; Serum Albumin; Signal Transduction; Staurosporine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

Topics: Alkaloids; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Butadienes; Caspases; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Jurkat Cells; Leukemia; MAP Kinase Signaling System; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Nitriles; Staurosporine; Tumor Cells, Cultured; U937 Cells

Topics: Acetophenones; Benzopyrans; Cell Division; Cycloheximide; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; GADD45 Proteins; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Kinetics; Leupeptins; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Proteins; Pyridines; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ubiquitins

Topics: Animals; Cell Line; Enzyme Inhibitors; Flavonoids; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Imidazoles; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prostaglandin D2; Pyridines; RNA, Messenger; Staurosporine

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Antibodies, Monoclonal; Calcium; Calcium-Binding Proteins; Carboxylic Ester Hydrolases; Carcinoma, Hepatocellular; Cell Division; Cell Nucleus; Clone Cells; Culture Media; DNA; Enzyme Inhibitors; Flavonoids; Intracellular Signaling Peptides and Proteins; Male; Protein Kinase Inhibitors; Rats; Rats, Wistar; Staurosporine; Sulfotransferases; Trifluoperazine

Topics: Anisomycin; Arsenites; Butadienes; Cadmium Chloride; Carcinogens; Dithiothreitol; Enzyme Inhibitors; Flavonoids; Glioma; Heat-Shock Proteins; Humans; Hydrogen Peroxide; Imidazoles; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nitriles; Osmotic Pressure; Oxidants; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Sodium Compounds; Sorbitol; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

Topics: Cell Differentiation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Indoles; Inhibitory Concentration 50; Interphase; Maleimides; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Naphthalenes; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Staurosporine; Transcription Factors; Tretinoin

Topics: Age Factors; Animals; Animals, Newborn; Bone Development; Cells, Cultured; Diaphyses; DNA; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Female; Femur; Flavonoids; Insulin-Like Growth Factor I; Male; Mitogen-Activated Protein Kinases; Nucleic Acid Synthesis Inhibitors; Picolinic Acids; Rats; Rats, Wistar; Staurosporine; Transforming Growth Factor beta; Zinc Sulfate

Topics: Acetylcysteine; Analgesics, Opioid; Animals; Antirheumatic Agents; Chloroquine; Cysteine Proteinase Inhibitors; Diprenorphine; Down-Regulation; Etorphine; Flavonoids; Genistein; GTP-Binding Proteins; Humans; Kidney; MAP Kinase Signaling System; Narcotic Antagonists; Neuroblastoma; Phosphorylation; Radioligand Assay; Receptors, Opioid, delta; Staurosporine; Teprotide; Transfection; Tritium; Tumor Cells, Cultured

Topics: 3T3 Cells; Acetophenones; Animals; Arsenates; Benzopyrans; Blotting, Northern; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Hydrogen Peroxide; Isoenzymes; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Peroxidases; Peroxiredoxins; Protein Binding; Protein Biosynthesis; Protein Kinase C; Protein Kinase C-delta; Protein Structure, Tertiary; RNA, Messenger; Signal Transduction; Staurosporine; Time Factors; Transcription, Genetic

Topics: Analysis of Variance; Animals; Butadienes; Calcium; Calcium Channel Blockers; Cell Line; Chelating Agents; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Gallic Acid; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Molecular Chaperones; Naphthalenes; Neoplasm Proteins; Nitriles; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Pyrrolidinones; Staurosporine; Stimulation, Chemical; Time Factors; Type C Phospholipases

Topics: Animals; Bone and Bones; Cycloheximide; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Estradiol; Flavonoids; Fracture Healing; Fractures, Bone; Insulin-Like Growth Factor I; Male; Parathyroid Hormone; Phosphoproteins; Rats; Rats, Wistar; Staurosporine; Time Factors; Transforming Growth Factor beta; Zinc

Topics: Blotting, Northern; Cell Cycle; Cell Division; Curcumin; Cyclin A; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Hypercholesterolemia; Immunoblotting; Luciferases; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Receptors, LDL; Signal Transduction; Staurosporine; Subcellular Fractions; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Up-Regulation

Topics: Adenocarcinoma; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Chromosome Mapping; Colonic Neoplasms; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Disease Progression; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

Topics: Adult; Antigens, CD34; Antigens, Differentiation; Butadienes; Carbazoles; Cell Cycle; Cell Differentiation; Cell Division; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoiesis; Erythropoietin; Flavonoids; Glycophorins; Hematopoietic Stem Cells; Humans; Indoles; Isoenzymes; Morpholines; Naphthalenes; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase C-alpha; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Staurosporine; Stem Cell Factor

Topics: Amanitins; Animals; Blotting, Western; Calcium-Binding Proteins; Carboxylic Ester Hydrolases; Cell Nucleus; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Intracellular Signaling Peptides and Proteins; Liver; Male; Nucleic Acid Synthesis Inhibitors; Rats; Rats, Wistar; Regeneration; RNA; Staurosporine; Sulfotransferases; Time Factors; Vanadates

Topics: Amino Acid Sequence; Cell Count; Cell Division; Cell Line; Cell Nucleus; Cytosol; Fatty Acids, Unsaturated; Flavonoids; Gene Expression Regulation, Enzymologic; Group IV Phospholipases A2; Humans; Imidazoles; Lectins; Models, Molecular; Molecular Sequence Data; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Conformation; Protein Transport; Pyridines; Staurosporine

Topics: Antineoplastic Agents; Apoptosis; Cell Survival; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Mitogen-Activated Protein Kinases; Nicotine; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Serine; Staurosporine; Tumor Cells, Cultured; Type C Phospholipases

Topics: Adenosine Triphosphate; Cell Division; DNA-Binding Proteins; Epithelium; ets-Domain Protein Elk-1; Female; Flavonoids; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Precancerous Conditions; Proto-Oncogene Proteins; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; RNA, Neoplasm; Staurosporine; Transcription Factors; Tumor Cells, Cultured

Topics: Animals; Apoptosis; Caspases; Cell Line; Chromones; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Isoquinolines; Macrophages; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Staurosporine; Sulfonamides

Topics: Androstadienes; Anilides; Animals; Annexin A5; Apoptosis; Carrier Proteins; Caspase 3; Caspases; Cell Death; Cell Survival; Chromones; Culture Media, Serum-Free; Flavonoids; Flow Cytometry; Humans; Imidazoline Receptors; Immunoblotting; Intracellular Signaling Peptides and Proteins; Morpholines; Oligopeptides; PC12 Cells; Proteins; Rats; Staurosporine; Thapsigargin; Transfection; Wortmannin

Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells

Topics: Animals; Bucladesine; Cell Differentiation; Central Nervous System; Dose-Response Relationship, Drug; Drug Synergism; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavonoids; MAP Kinase Signaling System; Neurites; PC12 Cells; Phosphorylation; Polycyclic Sesquiterpenes; Rats; Sesquiterpenes; Staurosporine

Topics: Androstadienes; Animals; Apoptosis; Cells, Cultured; Chromones; Coronary Vessels; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Flavonoids; Humans; Imidazoles; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Microscopy, Electron, Scanning; Microscopy, Video; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth, Vascular; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Signal Transduction; Staurosporine; Time Factors; Wortmannin

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Division; Cell Line; Cell Survival; Cholera Toxin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; fas Receptor; Flavonoids; Humans; Intestinal Mucosa; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Signal Transduction; Staurosporine; Time Factors

Topics: Adenosine Triphosphate; Animals; Calmodulin-Binding Proteins; Catalysis; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Flavonoids; Histamine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth, Vascular; Octoxynol; Phosphorylation; Staurosporine; Swine

Topics: Adenoviridae; Angiopoietin-2; Animals; Blotting, Northern; Blotting, Western; Butadienes; Carbazoles; Cattle; Cell Division; Disease Models, Animal; DNA; Enzyme Inhibitors; Flavonoids; Genes, Dominant; Humans; Hypoxia; Indoles; Maleimides; Mice; Models, Biological; Neovascularization, Pathologic; Neuropilin-1; Nitriles; Phosphorylation; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Reperfusion Injury; Retina; RNA, Messenger; Staurosporine; Time Factors; Transcription Factors; Up-Regulation; Vascular Endothelial Growth Factor A

Topics: Amino Acid Chloromethyl Ketones; Animals; Annexin A5; Antibodies, Monoclonal; Benzimidazoles; Blotting, Western; Caspase Inhibitors; Caspases; Cell Death; Cell Differentiation; Cell Line; Chromatin; Coumarins; Cytochromes c; Drug Interactions; Electrophoresis, Gel, Pulsed-Field; Enzyme Inhibitors; fas Receptor; Flavonoids; Fluorescent Dyes; Free Radical Scavengers; Immunohistochemistry; Metalloporphyrins; Mice; Mitochondria; Mitogen-Activated Protein Kinases; Naphthoquinones; Neurons; Oligopeptides; Propidium; Staurosporine; Stem Cells; Subcellular Fractions; Time Factors

Topics: alpha7 Nicotinic Acetylcholine Receptor; Antineoplastic Agents; Apoptosis; Bungarotoxins; Carcinogens; Carcinoma, Small Cell; Cell Division; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cisplatin; Enzyme Inhibitors; Flavonoids; Humans; Lung Neoplasms; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitrosamines; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Receptors, Nicotinic; RNA, Small Interfering; Signal Transduction; Staurosporine

Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Apoptosis; Calcium; Calcium Channel Agonists; Calcium-Binding Proteins; Calmodulin; Carboxylic Ester Hydrolases; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Death; Clone Cells; Dibucaine; Flavonoids; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Nitric Oxide Synthase; Protein Kinase Inhibitors; Rats; Staurosporine; Sulfotransferases; Tumor Cells, Cultured

Topics: Animals; Apoptosis; Blotting, Western; Cell Adhesion; Cell Line; Cell Survival; Cells, Cultured; Chromones; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibronectins; Fibrosis; Flavonoids; Flow Cytometry; Immunoprecipitation; Integrins; Ligands; MAP Kinase Signaling System; Mice; Microscopy, Confocal; Morpholines; Phosphatidylinositol 3-Kinases; Protein Binding; Signal Transduction; Staurosporine; Transfection

Topics: Amphiregulin; Androstadienes; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Line, Tumor; Culture Media, Serum-Free; EGF Family of Proteins; Enzyme Inhibitors; Flavonoids; Glycoproteins; Humans; Insulin-Like Growth Factor I; Intercellular Signaling Peptides and Proteins; Isoenzymes; Lung Neoplasms; MAP Kinase Signaling System; Models, Biological; Naphthalenes; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Staurosporine; Wortmannin

Topics: Androstadienes; Apoptosis; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, High Pressure Liquid; Diterpenes; Diterpenes, Kaurane; Enzyme Activation; Enzyme Inhibitors; Estrenes; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flow Cytometry; Humans; Molecular Structure; Phagocytosis; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrrolidinones; Staurosporine; Time Factors; Type C Phospholipases; U937 Cells; Ultraviolet Rays; Wortmannin

Topics: Analysis of Variance; Androstadienes; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Flavonoids; Histamine; Imidazoles; Indoles; Male; Maleimides; Mast Cells; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Kinase C; Pyridines; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Tyrosine; Wortmannin

Topics: Animals; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Enzymologic; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mice; Podocytes; Proto-Oncogene Protein c-ets-1; Smad2 Protein; Staurosporine; Transforming Growth Factor beta; Transforming Growth Factor beta1

Topics: Apoptosis; Cell Line, Tumor; Evodia; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Melanoma; Plant Extracts; Plants, Medicinal; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Staurosporine

Topics: Androstadienes; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Survival; Chromones; Enzyme Inhibitors; Etoposide; Flavonoids; Flow Cytometry; Humans; Indoles; Lung Neoplasms; MAP Kinase Kinase Kinases; Mitosis; Morpholines; Nocodazole; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Staurosporine; Wortmannin

Topics: Amyloid beta-Protein Precursor; Astrocytes; Cell Differentiation; Cells, Cultured; Excitatory Amino Acid Transporter 1; Flavonoids; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Promoter Regions, Genetic; Protein Kinase Inhibitors; RNA Interference; Staurosporine; Stem Cells

Topics: Apoptosis; CDC2 Protein Kinase; Cell Line, Tumor; Checkpoint Kinase 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Multiple Myeloma; Phosphorylation; Protein Kinases; RNA Interference; Staurosporine

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Base Sequence; Binding Sites; Blotting, Western; Calcium-Binding Proteins; Carboxylic Ester Hydrolases; Cell Line; Clone Cells; DNA-Binding Proteins; Epithelial Cells; Flavonoids; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins; Kidney Tubules, Proximal; Luciferases; Mutation; NFI Transcription Factors; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Signal Transduction; Staurosporine; Transfection

Topics: Aniline Compounds; Antibodies, Monoclonal; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Communication; Cell Line; Cells, Cultured; Estrenes; Extracellular Fluid; Flavonoids; Glucose; Humans; Immunohistochemistry; Indoles; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mitogen-Activated Protein Kinases; Phenethylamines; Propylamines; Protein Kinase C; Protein Kinases; Pyrrolidinones; Receptors, Calcium-Sensing; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Stimulation, Chemical; Sulfonamides; Type C Phospholipases

Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Benzamides; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activators; Flavonoids; Hypolipidemic Agents; In Vitro Techniques; Lipoprotein Lipase; Male; Muscle Contraction; Muscle, Smooth, Vascular; Organophosphorus Compounds; Phenylephrine; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Vasoconstriction; Vasodilation; Verapamil

Topics: Animals; Base Sequence; Benzodiazepinones; Cell Line, Tumor; Chromones; Dose-Response Relationship, Drug; Flavonoids; Gastric Mucosa; Gastrins; GC Rich Sequence; Genes, Reporter; Humans; Luciferases; MAP Kinase Kinase 1; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Morpholines; Mucins; Muscle Proteins; Mutation; Peptides; Phenylurea Compounds; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase Inhibitors; Receptor, Cholecystokinin B; RNA, Messenger; Signal Transduction; Staurosporine; Stomach; Time Factors; Transcription, Genetic; Transfection; Trefoil Factor-2

Topics: Cyclic AMP-Dependent Protein Kinases; Endocytosis; Flavonoids; Fluorescent Antibody Technique; Golgi Apparatus; Horseradish Peroxidase; HT29 Cells; Humans; Isoquinolines; Light; Mitogen-Activated Protein Kinases; Naphthalenes; Staurosporine; Sulfonamides

Topics: Adult; Aged; Antineoplastic Agents; Areca; Arecoline; Blotting, Western; Carcinoma, Squamous Cell; Curcumin; Epithelium; Female; Flavonoids; HSP70 Heat-Shock Proteins; Humans; Lymphatic Metastasis; Male; Mastication; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Staurosporine; Up-Regulation

Topics: Animals; Benzylamines; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP; Cytoskeleton; Flavonoids; Hippocampus; Homocysteine; Inositol Phosphates; Intermediate Filaments; Mitogen-Activated Protein Kinases; Models, Biological; Phosphorylation; Protein Kinase C; Rats; Receptors, N-Methyl-D-Aspartate; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Staurosporine; Sulfonamides; Type C Phospholipases

Topics: Animals; Astrocytes; Cells, Cultured; Endothelin B Receptor Antagonists; Endothelin-1; Endothelins; Flavonoids; Matrix Metalloproteinase 10; Matrix Metalloproteinase 11; Matrix Metalloproteinase 3; Protein Kinase Inhibitors; Rats; RNA, Messenger; Staurosporine

Topics: 3T3 Cells; Animals; Calcitriol; Calcium-Binding Proteins; Cell Differentiation; Dose-Response Relationship, Drug; Estradiol; Flavonoids; Hormones; Humans; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Mice; Osteoblasts; Parathyroid Hormone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Staurosporine; Tumor Necrosis Factor-alpha

Topics: Androstadienes; Animals; Butadienes; Calcium Signaling; Cell Line; Cricetinae; Endothelin-1; Epidermal Growth Factor; Flavonoids; Genistein; Humans; Indoles; Lysophospholipids; Maleimides; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Norepinephrine; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Adrenergic, alpha-1; RNA, Small Interfering; Staurosporine; Tetradecanoylphorbol Acetate; Wortmannin

Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Cell Line, Tumor; Cnidarian Venoms; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glioblastoma; Humans; MAP Kinase Signaling System; Marine Toxins; Mitogen-Activated Protein Kinases; Perforin; Phosphatidylinositol 3-Kinases; Protein Kinase C; Staurosporine; Thymidine

Topics: Acetylcysteine; Areca; Arecoline; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Cell Line; Cholinergic Agonists; Curcumin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Free Radical Scavengers; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Mouth Mucosa; Mouth Neoplasms; Protein Kinase C; Staurosporine; Time Factors; Transcription Factor AP-1

Topics: Carbazoles; Cell Degranulation; Complement C3b; Eosinophils; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine

Topics: Apoptosis; Cell Culture Techniques; Cell Survival; Cells, Cultured; Cellular Senescence; Child, Preschool; Diploidy; Fibroblasts; Flavonoids; Foreskin; Humans; Hydrogen Peroxide; Imidazoles; Interphase; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Pyridines; Staurosporine; Stress, Physiological; Wheat Germ Agglutinins