staurosporine has been researched along with okadaic acid in 169 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.59) | 18.7374 |
| 1990's | 111 (65.68) | 18.2507 |
| 2000's | 51 (30.18) | 29.6817 |
| 2010's | 6 (3.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balch, WE; Davidson, HW; McGowan, CH | 1 |
| Berthoud, VM; Hertzberg, EL; Ledbetter, ML; Sáez, JC | 1 |
| Hershkoviz, R; Lider, O; Miron, S; Schechter, Y; Tirosh, I; Yayun, A | 1 |
| Kiss, Z | 1 |
| Endo, Y; Furuya, S; Matsui, Y; Nozawa, S; Oba, M; Suzuki, S | 1 |
| Endo, Y; Furuya, S; Nozawa, S; Oba, M; Suzuki, S | 1 |
| Hedman, H; Lundgren, E | 1 |
| Chambers, TC; Kuo, JF; Zheng, B | 1 |
| Gschwendt, M; Kittstein, W; Lindner, D; Marks, F | 1 |
| DeBiasio, RL; Giuliano, KA; Kolega, J; Taylor, DL | 1 |
| Curtis, A; Gasmi, L | 1 |
| Deli, E; Kiss, Z | 1 |
| Hino, A; Isono, K; Magae, J; Nagai, K | 1 |
| Isono, K; Kurisaki, T; Magae, J; Nagai, K; Yamasaki, M | 1 |
| Livne, AA; Pouyssegur, J; Sardet, C | 1 |
| Hegg, GG; Karnovsky, MJ; Steinbeck, MJ | 1 |
| Aharonovitz, O; Fridman, H; Livne, AA; Markus, S; Tsukitani, Y | 1 |
| Haystead, TA; Krebs, EG; Licciardi, KA; Meier, KE | 1 |
| Fujiki, H; Hirota, M; Suganuma, M; Sugimura, T; Suguri, H; Takagi, K; Yoshizawa, S | 1 |
| Yang, SD; Yu, JS | 1 |
| Fishman, GI; Moreno, AP; Sáez, JC; Spray, DC | 1 |
| Adlersberg, M; al-Awqati, Q; Gershon, MD; Hsiung, SC; Liu, KP; Nicolaides, M; Nunez, EA; Piscopo, I; Tamir, H | 1 |
| Carter, V; Gale, M; Parsons, M | 1 |
| Chou, CF; Omary, MB | 1 |
| García-Sáinz, JA; González-Espinosa, C | 1 |
| Houslay, MD; Savage, A; Zeng, L | 1 |
| Nakajima, S; Nakajima, Y; Stanfield, PR; Takano, K | 1 |
| McCleskey, EW; Wilding, TJ; Womack, MD | 1 |
| Goshima, Y; Li, L; Strittmatter, SM; Xie, R | 1 |
| Desai, RK; Lian, JB; Stein, GS; Stein, JL; van Wijnen, AJ | 1 |
| Chida, K; Kuroki, T; Tagawa, T; Vogt, PK | 1 |
| Gahmberg, CG; Valmu, L | 1 |
| Aperia, A; Eklöf, AC; Greengard, P; Ibarra, F; Svensson, LB | 1 |
| Azzi, A; Boscoboinik, D; Galeotti, T | 1 |
| Bertrand, R; Jenkins, J; Pommier, Y; Solary, E | 1 |
| Alling, C; Larsson, C; Simonsson, P | 1 |
| Jesaitis, AJ; Klotz, KN | 1 |
| Brewer, CB; Roth, MG | 1 |
| Terrian, DM; Ways, DK | 1 |
| Aziz, F; De Luca, A; Desai, RK; Giordano, A; Graña, X; Jaarsveld, K; Last, TJ; Lian, JB; Soprano, K; van Wijnen, AJ | 1 |
| Anderson, HJ; Bradbury, EM; Guo, XW; Roberge, M; Swank, RA; Th'ng, JP; Tudan, C | 1 |
| Huttner, WB; Ohashi, M | 1 |
| Aikawa, M; Fujioka, H; Miller, LH; Ward, GE | 1 |
| Collins, CA; Ferro, KL; Lin, SX | 1 |
| Joggerst, B; Parton, RG; Simons, K | 1 |
| Alverez, J; Garcia-Sancho, J; Montero, M | 1 |
| Beauchamp, JR; Woodman, PG | 1 |
| Amara, FM; Chen, FY; Wright, JA | 1 |
| Crowell, DN | 1 |
| Gahmberg, CG; Kantor, C; Kovanen, P; Li, R; Nortamo, P; Timonen, T | 1 |
| Antoku, S; Nakamura, K | 1 |
| Baldini, P; Bellucci, V; Incerpi, S; Luly, P; Zannetti, A | 1 |
| Sakamoto, N; Shuntoh, H; Tanaka, C | 1 |
| Shechter, Y; Shisheva, A | 1 |
| Benistant, C; Gustavsson, L; Hoek, JB; Moehren, G; Rubin, R; Torres-Marquez, ME | 1 |
| Mayer, AM; Spitzer, JA | 1 |
| Brenner, HR; Britt, JC; Caroni, P; Rotzler, S | 1 |
| Finnegan, SG; Koenig, E; Lemmon, VP | 1 |
| Livne, AA; Packham, MA; Rand, ML; Ruben, DH | 1 |
| Greenwel, P; Hu, W; Kohanski, RA; Ramirez, F | 1 |
| Cohen, MB; Rokhlin, OW | 1 |
| Matsui, T; Yamaguchi, M | 2 |
| Goracci, G; Gresele, P; Iorio, P; Nenci, GG; Nucciarelli, F; Stasi, M; Vezza, R | 1 |
| Agnew, WS; Bendahhou, S; Cummins, TR; Potts, JF; Tong, J | 1 |
| el-Deiry, WS; Zeng, YX | 1 |
| Cherington, V; Corbley, MJ; Lydon, NB; Roberts, TM; Traxler, PM | 1 |
| Chock, PB; Huang, CY; Tekle, E; Zhu, DM | 1 |
| Asano, T; Hasegawa, K; Inaguma, Y; Ito, H; Kato, K; Kozawa, O | 1 |
| Dluzewski, AR; Garcia, CR | 1 |
| Vernon, RG | 1 |
| Fong, LG | 1 |
| Andersson, TB; Blomstrand, F; Sadar, MD | 1 |
| Matsumoto, Y; Tanimura, A; Tojyo, Y | 1 |
| Patzlaff, JS; Paulson, JR; Vallis, AJ | 1 |
| Atabay, C; Cagnoli, CM; Kharlamov, E; Manev, H; Uz, T | 1 |
| Arbuckle, J; Boddeke, HW; Boeijinga, P; Docherty, RJ; Meigel, I | 1 |
| Sansom, SC; Stockand, JD | 1 |
| Shaw, MK | 1 |
| Bhat, R; Bodwell, JE; Bresnick, E; Wagner, C; Weaver, JA | 1 |
| Londos, C; Rondinone, CM; Smith, UP; Zarnowski, MJ | 1 |
| Grumbles, RM; Howell, DS; Jeffrey, JJ; Shao, L | 1 |
| Eguchi, T; Ishida, H; Ishikawa, Y | 1 |
| Jorcano, JL; Paramio, JM | 1 |
| Baylink, DJ; Mohan, S; Sampath, K; Srinivasan, N | 1 |
| Cassimeris, L; Howell, B; Odde, DJ | 1 |
| Badwey, JA; Ding, J; Ellis, BA; Heyworth, PG; Robinson, JM | 1 |
| Agranoff, BW; Heacock, AM | 1 |
| Kramer, RH; Molokanova, E; Savchenko, A; Trivedi, B | 1 |
| Orchard, MA; Trotter, PJ; Walker, JH | 1 |
| Djamgoz, MB; Fraser, SP; Moon, C | 2 |
| Jones, SW; Kammermeier, PJ | 1 |
| Bize, I; Canessa, M; Dunham, PB; Muñoz, P | 1 |
| Badiani, K; Byers, DM; Cook, HW; Ridgway, ND | 1 |
| Hanahisa, Y; Murata, T; Takahashi, H; Yamaguchi, M | 1 |
| Blackhall, J; Fuentes, A; Magnusson, G; Muñoz, M | 1 |
| Ling, YH; Perez-Soler, R; Tornos, C | 1 |
| Berger, S; León, J; Rojo, E; Sánchez-Serrano, JJ; Titarenko, E; Vancanneyt, G | 1 |
| Auslender, M; Obejero-Paz, CA; Scarpa, A | 1 |
| Moreland, RS; Rokolya, A; Singer, HA; Walsh, MP | 1 |
| Haug, FM; Laake, JH; Ottersen, OP; Rundén, E; Seglen, PO; Shamloo, M; Wieloch, T | 1 |
| Anderson, HJ; Gowdy, PM; Roberge, M | 1 |
| Kuusisto, E; Kyrylenko, S; Roschier, M; Salminen, A | 1 |
| Masaki, T; Ono, K; Sakamoto, A; Satake, M | 1 |
| Breitbart, H; Luria, A; Rubinstein, S; Sun, QY | 1 |
| Fabre, S; Georget, V; Lobaccaro, JM; Lumbroso, S; Poujol, N; Sultan, C; Térouanne, B | 1 |
| Lian, JB; Montecino, M; Stein, GS; Stein, JL; van Wijnen, AJ | 1 |
| Cathala, L; Paupardin-Tritsch, D | 1 |
| Gefel, D; He, Z; Li, J; Sekar, N; Shechter, Y | 1 |
| Paramio, JM | 1 |
| Magga, J; Ruskoaho, H; Taskinen, P; Toth, M; Vuolteenaho, O | 1 |
| Gomes, R; Sampaio-Maia, B; Soares-da-Silva, P | 1 |
| Connelly, PS; Guild, GM; Shaw, MK; Tilney, LG; Vranich, KA | 1 |
| Danielpour, D; Hajouj, T; Hsing, AY; Kerner, H; Larisch-Bloch, S; Lechleider, RJ; Lotan, R; Roberts, AB; Roche, NS | 1 |
| Alcántara-Hernández, R; Gárcia-Sáinz, JA; Vázquez-Prado, J | 1 |
| Dudler, R; Freydl, E; Granado, J; Hassa, P; Wäspi, U | 1 |
| Antonelli, A; Cerasi, A; Columbaro, M; Falcieri, E; Luchetti, F; Magnani, M; Papa, S | 1 |
| Overholt, JL; Prabhakar, NR; Summers, BA | 1 |
| Kajiya, H; Okabe, K; Okamoto, F; Soeda, H; Takada, K | 1 |
| Boutin, JP; Dewaele, E; Druart, N; Goupil, P; Rambour, S | 1 |
| Imai, A; Nashida, T; Shimomura, H | 1 |
| Hara, K; Koizumi, N; Kusano, T; Sano, H; Yagi, M | 1 |
| Iwasaki, S; Kataoka, M; Sato, K; Sekiguchi, M; Shimazaki, Y; Takahashi, M | 1 |
| Dietrich, J; Geisler, C; Kastrup, J; Lauritsen, JP; Menné, C; Odum, N | 1 |
| Altiok, N; Changeux, JP | 1 |
| Crook, RB; Layne, J; Yip, S | 1 |
| Anguissola, S; Comoglio, PM; Giordano, S; Gual, P; Parker, PJ | 1 |
| Chang, SC; Cho, MH; Kang, BG; Kaufman, PB | 1 |
| Ahlgren, R; Døskeland, SO; Lillehaug, J; Sandal, T | 1 |
| Bernard, LP; Manzino, L; Sonsalla, PK; Zeevalk, GD | 1 |
| Chang, SC; Kaufman, PB | 1 |
| Alper, SL; Berton, G; Brugnara, C; Corato, C; De Franceschi, L; Fumagalli, L; Motta, R; Turrini, F; Veghini, E; Villa-Moruzzi, E | 1 |
| Correia, MA; Maltby, D; Medzihradszky, KF; Wang, X | 1 |
| Bahamonde, MI; Diaz, M; Hardy, SP; Lock, H; Muñoz, FJ; Posas, F; Valverde, MA | 1 |
| Balaraman, S; Kapoor, P; Madhubala, R; Raj, VS; Saxena, S | 1 |
| Egger, T; Goti, D; Hammer, A; Malle, E; Sattler, W; Wintersperger, A | 1 |
| Gaa, ST; Long, X; Rogers, TB; Wu, G | 1 |
| Jensen, AB; Mundy, J; Raventos, D | 1 |
| Chung, IK; Jin, E; Kim, WT; Yang, SW | 1 |
| Kurihara, K; Moore-Hoon, ML; Nakanishi, N; Turner, RJ | 1 |
| Knight, H; Knight, MR; Wright, AJ | 1 |
| Gimbrone, MA; Masuda, J; Ochi, H | 1 |
| Kim, HJ; Kim, J; Kim, YK; Park, JY | 1 |
| Ramonell, K; Somerville, S; Stacey, G; Zhang, B | 1 |
| Andrews, DA; Low, PS; Yang, L | 1 |
| Grewal, S; Morrison, EE; Ponnambalam, S; Walker, JH | 1 |
| De Souza, W; Limongi, CL; Rozental, S | 1 |
| Ciereszko, R; Dusza, L; Górska, T; Kaminska, B; Opalka, M | 1 |
| Bulgakov, VP; Fedoreyev, SA; Glazunov, VP; Mischenko, NP; Shkryl, YN; Tchernoded, GK; Zhuravlev, YN | 1 |
| duBell, WH; Rogers, TB | 1 |
| Hu, YX; Li, JY; Liu, XF; Wang, YX | 1 |
| Andreka, P; Bishopric, NH; Evans, WH; Haywood, GA; Martin, PE; Turner, MS; Webster, KA; You, L | 1 |
| Bełtowski, J; Borkowska, E; Jamroz-Wiśniewska, A; Marciniak, A; Wójcicka, G | 1 |
| Esclaire, F; Rametti, A; Terro, F; Yardin, C | 1 |
| Kishimoto, K; Matsui, K; Ozawa, R; Takabayashi, J | 1 |
| Fujita, R; Kawasaki, S; Kimura, S; Matsumoto, M; Sasaki, K; Watanabe, S | 1 |
| Harrison, RA; Jebe, E; Petrunkina, AM; Töpfer-Petersen, E; Tsolova, M | 1 |
| Betz, WJ; Gaffield, MA | 1 |
| Bai, GY; Kim, SH; Kim, SZ; Park, WH; Yuan, K | 1 |
| Cohen, IS; Doronin, SV; Potapova, IA | 1 |
| Bui, L; Konradsson, P; Magnusson, KE; Vikström, E | 1 |
| Jahnke, HG; Kurz, RG; Mack, TG; Pänke, O; Robitzki, AA; Rothermel, A; Sternberger, I; Striggow, F | 1 |
| Agalakova, NI; Gusev, GP | 1 |
| Bittencourt-Silvestre, J; de Souza, W; Lemgruber, L | 1 |
| Camacho, FG; Grima, EM; López, AM; Mirón, AS; Rodríguez, JJ | 1 |
| Chen, YC; Jeng, ST; Lin, CC; Lin, HH; Lin, JS | 1 |
| Imao, T; Nagata, S | 1 |
| Hirayama, N; Hisamitsu, T; Nakamura, TY; Shimada-Shimizu, N; Wakabayashi, S | 1 |
169 other study(ies) available for staurosporine and okadaic acid
| Article | Year |
|---|---|
Evidence for the regulation of exocytic transport by protein phosphorylation.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Cell Line; CHO Cells; Cricetinae; Endoplasmic Reticulum; Ethers, Cyclic; Exocytosis; Golgi Apparatus; Marine Toxins; Microcystins; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Phosphatase 2; Proteins; Staurosporine | 1992 |
Connexin43 in MDCK cells: regulation by a tumor-promoting phorbol ester and Ca2+.
Topics: Alkaloids; Animals; Calcium; Cell Adhesion; Cell Communication; Cell Membrane Permeability; Cells, Cultured; Connexins; Dogs; Ethers, Cyclic; Immunohistochemistry; Intercellular Junctions; Ionophores; Membrane Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinases; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Involvement of a protein kinase C and protein phosphatases in adhesion of CD4+ T cells to and detachment from extracellular matrix proteins.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; CD4 Antigens; Cell Adhesion; Cell Movement; Ethers, Cyclic; Fibronectins; Humans; Integrins; Isoquinolines; Laminin; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Staurosporine; T-Lymphocytes | 1992 |
The long-term combined stimulatory effects of ethanol and phorbol ester on phosphatidylethanolamine hydrolysis are mediated by a phospholipase C and prevented by overexpressed alpha-protein kinase C in fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Line; Enzyme Activation; Ethanol; Ethanolamines; Ethers, Cyclic; Fibroblasts; Hydrolysis; Isoenzymes; Isoquinolines; Mice; Mice, Inbred BALB C; Okadaic Acid; Phosphatidylethanolamines; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Protein phosphorylation regulates the mouse sperm acrosome reaction induced by the zona pellucida.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acrosome; Alkaloids; Animals; Diglycerides; Ethers, Cyclic; Exocytosis; Female; Genistein; Isoflavones; Isoquinolines; Male; Membrane Fusion; Mice; Okadaic Acid; Phorbol Esters; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Signal Transduction; Sperm-Ovum Interactions; Staurosporine; Tetradecanoylphorbol Acetate; Zona Pellucida | 1992 |
Effects of modulators of protein kinases and phosphatases on mouse sperm capacitation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bucladesine; Chlortetracycline; Dibutyryl Cyclic GMP; Diglycerides; Ethers, Cyclic; Fluorescence; Genistein; Isoflavones; Isoquinolines; Male; Mice; Okadaic Acid; Peptide Fragments; Phorbol Esters; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Sperm Capacitation; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Regulation of LFA-1 avidity in human B cells. Requirements for dephosphorylation events for high avidity ICAM-1 binding.
Topics: Alkaloids; B-Lymphocytes; Cell Adhesion Molecules; Cells, Cultured; Ethers, Cyclic; Humans; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Staurosporine | 1992 |
Regulation by phorbol ester and protein kinase C inhibitors, and by a protein phosphatase inhibitor (okadaic acid), of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human KB cells.
Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance; Ethers, Cyclic; Humans; KB Cells; Membrane Glycoproteins; Naphthalenes; Okadaic Acid; Peptide Mapping; Phenotype; Phospholipid Ethers; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Vinblastine | 1992 |
Differential inhibition by staurosporine of phorbol ester, bryostatin and okadaic acid effects on mouse skin.
Topics: Alkaloids; Animals; Bryostatins; Cyclosporine; Edema; Ethers, Cyclic; Female; Lactones; Macrolides; Mice; Okadaic Acid; Protein Kinase C; Skin; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Myosin II phosphorylation and the dynamics of stress fibers in serum-deprived and stimulated fibroblasts.
Topics: 3T3 Cells; Alkaloids; Animals; Cell Size; Culture Media; Cytochalasin D; Ethers, Cyclic; Gels; Mice; Myosins; Okadaic Acid; Phosphorylation; Staurosporine | 1992 |
The effects of staurosporine and okadaic acid on baby hamster kidney fibroblast cell adhesion.
Topics: Alkaloids; Animals; Cell Adhesion; Cell Line; Cell Size; Cricetinae; Dose-Response Relationship, Drug; Ethers, Cyclic; Fibroblasts; Okadaic Acid; Protein Kinase C; Staurosporine | 1992 |
Regulation of phospholipase D by sphingosine involves both protein kinase C-dependent and -independent mechanisms in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Alkaloids; Animals; Bryostatins; Down-Regulation; Drug Interactions; Ethers, Cyclic; Hydrolysis; Lactones; Macrolides; Mice; Okadaic Acid; Phosphatidylethanolamines; Phospholipase D; Phospholipids; Platelet-Derived Growth Factor; Protein Kinase C; Sphingomyelin Phosphodiesterase; Sphingosine; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1992 |
Respiratory burst induced by phorbol ester in the presence of tautomycin, a novel inhibitor of protein phosphatases.
Topics: Alkaloids; Animals; Antifungal Agents; Cells, Cultured; Dogs; Echinomycin; Ethers, Cyclic; Hydrogen Peroxide; Nitroblue Tetrazolium; Okadaic Acid; Phorbol 12,13-Dibutyrate; Pyrans; Respiratory Burst; Spiro Compounds; Staurosporine | 1992 |
Effects of tautomycin, a protein phosphatase inhibitor, on recycling of mammalian cell surface molecules.
Topics: Alkaloids; Antifungal Agents; Carbazoles; CD4 Antigens; Down-Regulation; Ethers, Cyclic; Indole Alkaloids; Okadaic Acid; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrans; Receptors, Transferrin; Spiro Compounds; Staurosporine | 1992 |
The Na+/H+ exchanger is phosphorylated in human platelets in response to activating agents.
Topics: Alkaloids; Blood Platelets; Carrier Proteins; Diglycerides; Ethers, Cyclic; Humans; Hydrogen-Ion Concentration; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 1; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Arachidonate activation of the neutrophil NADPH-oxidase. Synergistic effects of protein phosphatase inhibitors compared with protein kinase activators.
Topics: Alkaloids; Animals; Arachidonic Acids; Enzyme Activation; Ethers, Cyclic; Guinea Pigs; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Retinoids; Staurosporine; Superoxides | 1991 |
Modulation of Na+/H+ exchange and intracellular pH by protein kinase C and protein phosphatase in blood platelets.
Topics: Alkaloids; Blood Platelets; Carrier Proteins; Cytoplasm; Diglycerides; Ethers, Cyclic; Fluoresceins; Humans; Hydrogen-Ion Concentration; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Activation of messenger-independent protein kinases in wild-type and phorbol ester-resistant EL4 thymoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Ethers, Cyclic; Glycogen Synthase Kinase 3; Isoquinolines; Mice; Molecular Sequence Data; Okadaic Acid; Oligopeptides; Phosphoproteins; Piperazines; Protein Kinase C; Protein Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 1991 |
Diversity in the chemical nature and mechanism of response to tumor promoters.
Topics: Acrylamides; Alkaloids; Animals; Carcinogenicity Tests; Carcinogens; Cells, Cultured; Cnidarian Venoms; Enzyme Induction; Ethers, Cyclic; Mice; Okadaic Acid; Ornithine Decarboxylase; Plant Extracts; Plants, Medicinal; Protein Kinase C; Skin; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Vasoconstrictor Agents | 1989 |
Okadaic acid, a serine/threonine phosphatase inhibitor, induces tyrosine dephosphorylation/inactivation of protein kinase FA/GSK-3 alpha in A431 cells.
Topics: Alkaloids; Amino Acid Sequence; Antibodies; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Glycogen Synthase Kinase 3; Humans; Immunoblotting; Kinetics; Molecular Sequence Data; Molecular Weight; Okadaic Acid; Oligopeptides; Phosphoprotein Phosphatases; Phosphotyrosine; Protein Kinase C; Staurosporine; Tumor Cells, Cultured; Tyrosine | 1994 |
Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation.
Topics: Alkaloids; Cells, Cultured; Connexin 43; Ethers, Cyclic; Gap Junctions; Humans; Ion Channels; Okadaic Acid; Phosphorylation; Staurosporine | 1994 |
Secretogogue-induced gating of chloride channels in the secretory vesicles of parafollicular cells.
Topics: Acridine Orange; Alkaloids; Animals; Barium; Calcium; Calmodulin; Chloride Channels; Chlorides; Cyclosporine; Electron Probe Microanalysis; Ethers, Cyclic; Immunoblotting; Immunohistochemistry; Intracellular Membranes; Ion Channel Gating; Okadaic Acid; Phorbol Esters; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein Kinase Inhibitors; Serotonin; Sheep; Staurosporine; Tacrolimus; Thyroid Gland; Thyrotropin | 1994 |
Cell cycle-specific induction of an 89 kDa serine/threonine protein kinase activity in Trypanosoma brucei.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Catechols; Cell Cycle; Cell Division; Cycloheximide; DNA; Enzyme Induction; Ethers, Cyclic; Flow Cytometry; Genistein; Isoflavones; Isoquinolines; Molecular Weight; Nitriles; Okadaic Acid; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Denaturation; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; S Phase; Staurosporine; Trypanosoma brucei brucei; Tyrosine; Tyrphostins | 1994 |
Mitotic arrest with anti-microtubule agents or okadaic acid is associated with increased glycoprotein terminal GlcNAc's.
Topics: Acetylglucosamine; Acid Phosphatase; Alkaloids; Aphidicolin; Brefeldin A; Cell Cycle; Cell Line; Colon; Cyclopentanes; Epithelium; Ethers, Cyclic; G2 Phase; Glycoproteins; Glycosylation; Golgi Apparatus; HeLa Cells; Humans; Keratins; Microtubules; Mitosis; Nocodazole; Okadaic Acid; Protein Kinase C; Protein Synthesis Inhibitors; Staurosporine | 1994 |
Protein kinases and phosphatases modulate c-fos expression in rat hepatocytes. Effects of angiotensin II and phorbol myristate acetate.
Topics: Alkaloids; Angiotensin II; Animals; Ethers, Cyclic; Female; Gene Expression; Genes, fos; Genistein; Isoflavones; Marine Toxins; Microcystins; Naphthalenes; Okadaic Acid; Oxazoles; Peptides, Cyclic; Phosphoprotein Phosphatases; Phosphorylation; Polycyclic Compounds; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
A role for protein kinase C-mediated phosphorylation in eliciting glucagon desensitization in rat hepatocytes.
Topics: Adenylyl Cyclases; Alkaline Phosphatase; Alkaloids; Animals; Arginine Vasopressin; Benzophenanthridines; Cell Adhesion; Cells, Cultured; Collagen; Cyclic AMP; Drug Tolerance; Ethers, Cyclic; Glucagon; Liver; Male; Naphthalenes; Okadaic Acid; Phenanthridines; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine | 1995 |
Protein kinase C-mediated inhibition of an inward rectifier potassium channel by substance P in nucleus basalis neurons.
Topics: Alkaloids; Animals; Cells, Cultured; Ethers, Cyclic; Neurons; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Rats; Signal Transduction; Staurosporine; Substance P; Substantia Innominata | 1995 |
Fast, local signal transduction between the mu opioid receptor and Ca2+ channels.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Bucladesine; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethers, Cyclic; Ganglia, Spinal; Kinetics; Microcystins; Neurons, Afferent; Okadaic Acid; Patch-Clamp Techniques; Peptides, Cyclic; Pertussis Toxin; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Opioid, mu; Second Messenger Systems; Signal Transduction; Staurosporine; Time Factors; Virulence Factors, Bordetella | 1995 |
An activated mutant of the alpha subunit of G(o) increases neurite outgrowth via protein kinase C.
Topics: Alkaloids; Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethers, Cyclic; Gallic Acid; GTP-Binding Proteins; Mutation; Neurites; Okadaic Acid; PC12 Cells; Protein Kinase C; Rats; Second Messenger Systems; Staurosporine; Terpenes; Thapsigargin; Transfection | 1995 |
Control of 1,25-dihydroxyvitamin D3 receptor-mediated enhancement of osteocalcin gene transcription: effects of perturbing phosphorylation pathways by okadaic acid and staurosporine.
Topics: Alkaloids; Animals; Enzyme Inhibitors; Ethers, Cyclic; Okadaic Acid; Osteocalcin; Phosphoprotein Phosphatases; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Rats; Receptors, Calcitriol; Receptors, Retinoic Acid; Retinoid X Receptors; Staurosporine; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
The cell cycle-dependent nuclear import of v-Jun is regulated by phosphorylation of a serine adjacent to the nuclear localization signal.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Animals; Biological Transport; Cell Cycle; Cell Nucleus; Cells, Cultured; Chick Embryo; Cytoplasm; Ethers, Cyclic; Fibroblasts; Isoquinolines; Molecular Sequence Data; Nuclear Localization Signals; Nuclear Proteins; Okadaic Acid; Oncogene Protein p65(gag-jun); Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperazines; Protein Kinases; Staurosporine | 1995 |
Treatment with okadaic acid reveals strong threonine phosphorylation of CD18 after activation of CD11/CD18 leukocyte integrins with phorbol esters or CD3 antibodies.
Topics: Alkaloids; CD11 Antigens; CD18 Antigens; Cell Aggregation; Ethers, Cyclic; Humans; Muromonab-CD3; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphothreonine; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Staurosporine; T-Lymphocyte Subsets; Threonine | 1995 |
Bidirectional regulation of Na+,K(+)-ATPase activity by dopamine and an alpha-adrenergic agonist.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Alkaloids; Animals; Calcimycin; Denervation; Dopamine; Dopamine Agents; Ethers, Cyclic; Fenoldopam; In Vitro Techniques; Kidney; Kidney Tubules; Kinetics; Male; Okadaic Acid; Oxymetazoline; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tacrolimus | 1993 |
Regulation of the TNF-alpha receptor in human osteosarcoma cells: role of microtubules and of protein kinase C.
Topics: Alkaloids; Cell Membrane; Cycloheximide; Ethers, Cyclic; Humans; Kinetics; Microtubules; Naphthalenes; Okadaic Acid; Osteosarcoma; Phosphoprotein Phosphatases; Polycyclic Compounds; Protein Kinase C; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vinblastine | 1993 |
Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Aphidicolin; Apoptosis; Benzamides; Calcium; Calmodulin; Camptothecin; Cell Cycle; Chromatin; Cyclosporine; DNA; Egtazic Acid; Ethers, Cyclic; Humans; Isoquinolines; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Polycyclic Compounds; Protein Kinase C; Spermine; Staurosporine; Teniposide; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc | 1993 |
An okadaic acid-sensitive protein phosphatase counteracts protein kinase C-induced phosphorylation in SH-SY5Y cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Calcium; Cell Membrane Permeability; Diglycerides; Ethers, Cyclic; Humans; Isoenzymes; Isoquinolines; Molecular Sequence Data; Myelin Basic Protein; Neoplasm Proteins; Neuroblastoma; Okadaic Acid; Peptide Fragments; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Polymyxin B; Protein Kinase C; Protein Phosphatase 2; Protein Processing, Post-Translational; Signal Transduction; Staurosporine; Substrate Specificity; Tumor Cells, Cultured | 1993 |
The interaction of N-formyl peptide chemoattractant receptors with the membrane skeleton is energy-dependent.
Topics: Alkaloids; Cell Membrane; Energy Metabolism; Ethers, Cyclic; Humans; Neutrophils; Okadaic Acid; Phosphorylation; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Staurosporine | 1994 |
Polarized exocytosis in MDCK cells is regulated by phosphorylation.
Topics: Alkaloids; Animals; Cell Line; Cell Membrane; Cell Polarity; Chlorocebus aethiops; Dogs; Ethers, Cyclic; Exocytosis; Golgi Apparatus; GTP-Binding Proteins; Kidney; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Staurosporine | 1995 |
Persistent enhancement of sustained calcium-dependent glutamate release by phorbol esters: role of calmodulin-independent serine/threonine phosphorylation and actin disassembly.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Alkaloids; Animals; Barium; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cytochalasin D; Ethers, Cyclic; Glutamates; Guinea Pigs; Hippocampus; Isoquinolines; Male; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Phosphotransferases; Piperazines; Protein Kinase C; Serine; Sphingosine; Staurosporine; Subcellular Fractions; Sulfonamides; Synaptosomes; Threonine | 1995 |
Transcription of histone H4, H3, and H1 cell cycle genes: promoter factor HiNF-D contains CDC2, cyclin A, and an RB-related protein.
Topics: Alkaloids; Base Sequence; CDC2 Protein Kinase; Cell Cycle; Cyclins; DNA-Binding Proteins; Ethers, Cyclic; Gene Expression Regulation; Histones; Humans; In Vitro Techniques; Macromolecular Substances; Molecular Sequence Data; Okadaic Acid; Oligodeoxyribonucleotides; Phosphorylation; Promoter Regions, Genetic; Retinoblastoma Protein; RNA, Messenger; Staurosporine; Transcription Factors; Transcription, Genetic; Transcriptional Activation | 1994 |
Chromosome condensation induced by fostriecin does not require p34cdc2 kinase activity and histone H1 hyperphosphorylation, but is associated with enhanced histone H2A and H3 phosphorylation.
Topics: Alkaloids; Alkenes; Animals; CDC2 Protein Kinase; Chromosomes; Cyclins; Ethers, Cyclic; G2 Phase; Genes, cdc; Histones; Mice; Mitosis; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Polyenes; Protamine Kinase; Protein Kinase C; Protein Phosphatase 1; Pyrones; Staurosporine; Temperature; Tumor Cells, Cultured | 1995 |
An elevation of cytosolic protein phosphorylation modulates trimeric G-protein regulation of secretory vesicle formation from the trans-Golgi network.
Topics: Alkaloids; Animals; Cytosol; Ethers, Cyclic; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Okadaic Acid; PC12 Cells; Phosphoproteins; Phosphorylation; Rats; Staurosporine; Vacuoles | 1994 |
Staurosporine inhibits invasion of erythrocytes by malarial merozoites.
Topics: Alkaloids; Animals; Erythrocytes; Ethers, Cyclic; Macaca mulatta; Microscopy, Electron; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Plasmodium knowlesi; Protein Kinase C; Signal Transduction; Staurosporine | 1994 |
Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Alkaloids; Animals; Bucladesine; Calcimycin; Calmodulin; Cell Line; Colforsin; Culture Media; Cytoplasm; Dyneins; Edetic Acid; Ethers, Cyclic; Imidazoles; Kidney; Kinetics; Macromolecular Substances; Okadaic Acid; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate | 1994 |
Regulated internalization of caveolae.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Biological Transport; Caveolin 1; Caveolins; Cell Line; Cell Membrane; Cytochalasin D; Ethers, Cyclic; Genistein; Hypertonic Solutions; Isoflavones; Membrane Proteins; Microscopy, Electron; Microtubules; Nocodazole; Okadaic Acid; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Chemotactic peptide down-regulation of calcium mobilization induced by platelet-activating factor and by leukotriene B4 in human neutrophils is uncovered by protein phosphatase inhibitors.
Topics: Alkaloids; Calcium; Down-Regulation; Ethers, Cyclic; Humans; Indoles; Leukotriene B4; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Oxazoles; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Staurosporine | 1994 |
Regulation of transferrin receptor recycling by protein phosphorylation.
Topics: Adenosine Triphosphate; Alkaloids; Binding Sites; Cell Line; Cell Survival; Deferoxamine; DNA; Endocytosis; Ethers, Cyclic; HeLa Cells; Humans; Isotope Labeling; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Receptors, Transferrin; Staurosporine; Transferrin | 1994 |
Regulation of mammalian ribonucleotide reductase R1 mRNA stability is mediated by a ribonucleotide reductase R1 mRNA 3'-untranslated region cis-trans interaction through a protein kinase C-controlled pathway.
Topics: 3T3 Cells; Alkaloids; Animals; Binding Sites; Cell Line; Chloramphenicol O-Acetyltransferase; Ethers, Cyclic; Haplorhini; Mice; Mice, Inbred BALB C; Okadaic Acid; Protein Biosynthesis; Protein Kinase C; Ribonucleotide Reductases; RNA-Binding Proteins; RNA, Messenger; Signal Transduction; Staurosporine | 1994 |
Cytokinin regulation of a soybean pollen allergen gene.
Topics: Alkaloids; Allergens; Amino Acid Sequence; Antigens, Plant; Base Sequence; Cells, Cultured; Cytokinins; Ethers, Cyclic; Gene Expression Regulation; Genes, Plant; Glycine max; Molecular Sequence Data; Okadaic Acid; Phosphoprotein Phosphatases; Plant Proteins; Pollen; Protein Kinase C; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Soybean Proteins; Staurosporine | 1994 |
A leukocyte integrin binding peptide from intercellular adhesion molecule-2 stimulates T cell adhesion and natural killer cell activity.
Topics: Alkaloids; Amino Acid Sequence; Antigens, CD; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cytotoxicity, Immunologic; Ethers, Cyclic; Humans; Integrins; Killer Cells, Natural; Lymphocyte Function-Associated Antigen-1; Molecular Sequence Data; Okadaic Acid; Peptide Fragments; Protein Binding; Protein Kinase C; Receptors, Leukocyte-Adhesion; Staurosporine; T-Lymphocytes; Tumor Cells, Cultured | 1993 |
Protein kinase inhibitor, staurosporine, prevents okadaic acid- or caffeine-induced chromosome condensation.
Topics: Alkaloids; Animals; Caffeine; Cells, Cultured; Chromosomes; Cricetinae; Drug Interactions; Enzyme Activation; Ethers, Cyclic; Mitosis; Okadaic Acid; Protamine Kinase; Protein Kinase Inhibitors; Staurosporine | 1993 |
Modulation of the Na-H antiport by insulin: interplay between protein kinase C, tyrosine kinase, and protein phosphatases.
Topics: Alkaloids; Animals; Ethers, Cyclic; Insulin; Male; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Protein phosphatase inhibitors induce the release of serotonin from rat basophilic leukemia cells (RBL-2H3).
Topics: Alkaloids; Animals; Calcium; Ethers, Cyclic; Leukemia, Basophilic, Acute; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Rats; Serotonin; Staurosporine; Tumor Cells, Cultured | 1994 |
A dynamic system for suppression and re-expression of insulin and pervanadate bioresponses in rat adipocytes. Treatment with okadaic acid and staurosporine.
Topics: Adipose Tissue; Alkaloids; Animals; Drug Interactions; Ethers, Cyclic; Gene Expression Regulation; Insulin; Lipolysis; Male; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Rats; Rats, Wistar; Staurosporine; Vanadates | 1994 |
The role of cytosolic Ca2+, protein kinase C, and protein kinase A in hormonal stimulation of phospholipase D in rat hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ethers, Cyclic; Glycerophospholipids; Isoquinolines; Liver; Male; Okadaic Acid; Phosphatidic Acids; Phospholipase D; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasopressins | 1994 |
Modulation of superoxide generation in in vivo lipopolysaccharide-primed Kupffer cells by staurosporine, okadaic acid, manoalide, arachidonic acid, genistein and sodium orthovanadate.
Topics: Alkaloids; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Enzyme Inhibitors; Ethers, Cyclic; Genistein; In Vitro Techniques; Isoflavones; Kupffer Cells; Lipopolysaccharides; Male; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Staurosporine; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Vanadates | 1994 |
Calcium influx and protein phosphorylation mediate the metabolic stabilization of synaptic acetylcholine receptors in muscle.
Topics: Alkaloids; Animals; Bucladesine; Calcium; Calcium Channels; Cyclic AMP; Dibutyryl Cyclic GMP; Dihydropyridines; Electric Stimulation; Ethers, Cyclic; Kinetics; Male; Marine Toxins; Motor Endplate; Muscle Denervation; Muscles; Okadaic Acid; Organ Culture Techniques; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Staurosporine; Synapses; Tetrodotoxin; Time Factors | 1993 |
Monoclonal antibody 8A2-induced retraction appears to be mediated by protein phosphorylation in goldfish retinal ganglion cell axons.
Topics: Alkaloids; Animals; Antibodies, Monoclonal; Axons; Calcium; Cyclic AMP; Ethers, Cyclic; Goldfish; Nerve Regeneration; Okadaic Acid; Organ Culture Techniques; Phorbol Esters; Phorbols; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Retinal Ganglion Cells; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Activation of phospholipase C and protein kinase C has little involvement in ADP-induced primary aggregation of human platelets: effects of diacylglycerols, the diacylglycerols, the diacylglycerol kinase inhibitor R59022, staurosporine and okadaic acid.
Topics: Adenosine Diphosphate; Alkaloids; Blood Platelets; Diacylglycerol Kinase; Diglycerides; Enzyme Activation; Ethers, Cyclic; Humans; Okadaic Acid; Phosphotransferases; Platelet Aggregation; Protein Kinase C; Pyrimidinones; Serotonin; Staurosporine; Thiazoles; Thrombin; Type C Phospholipases | 1993 |
Tyrosine dephosphorylation of nuclear proteins mimics transforming growth factor beta 1 stimulation of alpha 2(I) collagen gene expression.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Collagen; Enzyme Inhibitors; Ethers, Cyclic; Fetus; Fibroblasts; Gene Expression; Genistein; Humans; Isoflavones; Isoquinolines; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphotyrosine; Piperazines; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Skin; Staurosporine; Transcription, Genetic; Transforming Growth Factor beta; Vanadates | 1995 |
Differential sensitivity of human prostatic cancer cell lines to the effects of protein kinase and phosphatase inhibitors.
Topics: Alkaloids; Antigens, CD; Antigens, Neoplasm; Cell Adhesion Molecules; Cell Division; Endoglin; Enzyme Inhibitors; Ethers, Cyclic; Genistein; Humans; Hyaluronan Receptors; Intercellular Adhesion Molecule-1; Isoflavones; Male; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Cell Surface; Staurosporine; Tumor Cells, Cultured; Vanadates; Vascular Cell Adhesion Molecule-1 | 1995 |
Zinc modulation of insulin-like growth factor's effect in osteoblastic MC3T3-E1 cells.
Topics: 3T3 Cells; Alkaline Phosphatase; Alkaloids; Animals; Carnosine; Cycloheximide; DNA; Drug Synergism; Enzyme Inhibitors; Ethers, Cyclic; Insulin; Insulin-Like Growth Factor I; Mice; Okadaic Acid; Organometallic Compounds; Osteoblasts; Protein Synthesis Inhibitors; Proteins; Staurosporine; Zinc; Zinc Compounds | 1995 |
Protein kinase C inhibitors enhance G-protein induced phospholipase A2 activation in intact human platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aluminum Compounds; Arachidonic Acid; beta-Thromboglobulin; Blood Platelets; Enzyme Activation; Enzyme Inhibitors; Ethers, Cyclic; Fluorides; GTP-Binding Proteins; Humans; Isoquinolines; Kinetics; Naphthalenes; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Piperazines; Platelet Aggregation; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1996 |
Serine-1321-independent regulation of the mu 1 adult skeletal muscle Na+ channel by protein kinase C.
Topics: Adult; Alkaloids; Amino Acid Sequence; Base Sequence; Cell Line; Consensus Sequence; Conserved Sequence; DNA Primers; Enzyme Inhibitors; Ethers, Cyclic; Humans; Ion Channel Gating; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Multiple Sclerosis; Muscle, Skeletal; Mutagenesis, Site-Directed; Naphthalenes; Okadaic Acid; Phosphorylation; Polymerase Chain Reaction; Polyradiculoneuropathy; Protein Kinase C; Recombinant Proteins; Serine; Sodium Channels; Staurosporine; Transfection | 1995 |
Regulation of p21WAF1/CIP1 expression by p53-independent pathways.
Topics: Alkaloids; Blood; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Ethers, Cyclic; Gene Expression Regulation; Genes, p53; Humans; Okadaic Acid; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
A strategy for screening anti-tumor drugs utilizing oncogenes encoded in retroviral vectors.
Topics: 3T3 Cells; Alkaloids; Animals; Antigens, Polyomavirus Transforming; Benzamides; Cell Division; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Ethers, Cyclic; Genes, ras; Genes, src; Genetic Vectors; Hydroquinones; Mice; Okadaic Acid; Oncogenes; Phenols; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Retroviridae; Signal Transduction; Staurosporine; Styrenes; Sulfones; Thiazoles | 1996 |
Reversible phosphorylation as a controlling factor for sustaining calcium oscillations in HeLa cells: Involvement of calmodulin-dependent kinase II and a calyculin A-inhibitable phosphatase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Binding Sites; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Enzyme Inhibitors; Ethers, Cyclic; HeLa Cells; Histamine; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoquinolines; Maleimides; Marine Toxins; Molecular Sequence Data; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; Ryanodine; Spectrometry, Fluorescence; Staurosporine; Sulfonamides | 1996 |
Modulation of the stress-induced synthesis of stress proteins by a phorbol ester and okadaic acid.
Topics: Alkaloids; Animals; Arachidonic Acid; Arsenites; Blotting, Northern; Blotting, Western; Enzyme Activation; Ethers, Cyclic; Glioma; Heat-Shock Proteins; Okadaic Acid; Protein Kinase C; Rats; RNA, Messenger; Serine Proteinase Inhibitors; Staurosporine; Stimulation, Chemical; Stress, Physiological; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Inhibition of invasion and intraerythrocytic development of Plasmodium falciparum by kinase inhibitors.
Topics: Alkaloids; Animals; Antimalarials; Benzylidene Compounds; Cinnamates; Enzyme Inhibitors; Erythrocytes; Ethers, Cyclic; Genistein; Humans; Isoflavones; Nitriles; Okadaic Acid; Phenols; Phosphoric Monoester Hydrolases; Plasmodium falciparum; Protein Kinase Inhibitors; Staurosporine; Tyrphostins | 1996 |
GH inhibition of lipogenesis and stimulation of lipolysis in sheep adipose tissue: involvement of protein serine phosphorylation and dephosphorylation and phospholipase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetyl-CoA Carboxylase; Adipose Tissue; Alkaloids; Animals; Bridged-Ring Compounds; Culture Techniques; Ethers, Cyclic; Glycerol; Growth Hormone; Isoquinolines; Lipid Metabolism; Lipids; Lipolysis; Male; Norbornanes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Sheep; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Type C Phospholipases | 1996 |
Modulation of macrophage scavenger receptor transport by protein phosphorylation.
Topics: Animals; Blotting, Northern; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Pinocytosis; Protein Binding; Protein Kinase C; Receptors, Immunologic; Receptors, Scavenger; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Phenobarbital induction of cytochrome P4501A1 is regulated by cAMP-dependent protein kinase-mediated signaling pathways in rainbow trout hepatocytes.
Topics: Alkaloids; Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; DNA Primers; Enzyme Induction; Enzyme Inhibitors; Epinephrine; Ethers, Cyclic; Liver; Molecular Sequence Data; Okadaic Acid; Oncorhynchus mykiss; Phenobarbital; Polychlorinated Dibenzodioxins; RNA, Messenger; Signal Transduction; Staurosporine | 1996 |
Suppression of capacitative Ca2+ entry by serine/threonine phosphatase inhibitors in rat parotid acinar cells.
Topics: Alkaloids; Animals; Antifungal Agents; Calcium; Carbachol; Enzyme Inhibitors; Ethers, Cyclic; Male; Okadaic Acid; Parotid Gland; Phosphoric Monoester Hydrolases; Pyrans; Rats; Rats, Wistar; Spiro Compounds; Staurosporine | 1995 |
Evidence that the endogenous histone H1 phosphatase in HeLa mitotic chromosomes is protein phosphatase 1, not protein phosphatase 2A.
Topics: Cell Nucleus; Chromatin; Enzyme Inhibitors; HeLa Cells; Histones; Humans; Kinetin; Marine Toxins; Metaphase; Microcystins; Mitosis; Okadaic Acid; Oxazoles; Peptides, Cyclic; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 1; Protein Phosphatase 2; Purines; Staurosporine | 1996 |
Apoptosis induced in neuronal cultures by either the phosphatase inhibitor okadaic acid or the kinase inhibitor staurosporine is attenuated by isoquinolinesulfonamides H-7, H-8, and H-9.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Cells, Cultured; Cerebellum; Enzyme Inhibitors; Isoquinolines; Neurons; Okadaic Acid; Phosphoric Monoester Hydrolases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Sulfonamides | 1996 |
Modulation by calcineurin of 5-HT3 receptor function in NG108-15 neuroblastoma x glioma cells.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Brain Neoplasms; Calcineurin; Calmodulin-Binding Proteins; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Glioma; Half-Life; Molecular Sequence Data; Neuroblastoma; Okadaic Acid; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Rats; Receptors, Serotonin; Staurosporine; Tumor Cells, Cultured | 1996 |
Mechanism of activation by cGMP-dependent protein kinase of large Ca(2+)-activated K+ channels in mesangial cells.
Topics: Adenosine Triphosphate; Alkaloids; Calcium; Carbazoles; Cells, Cultured; Cyclic GMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Humans; Indoles; Kinetics; Membrane Potentials; Okadaic Acid; Patch-Clamp Techniques; Potassium Channels; Protein Kinase Inhibitors; Pyrroles; Staurosporine | 1996 |
Theileria parva sporozoite entry into bovine lymphocytes involves both parasite and host cell signal transduction processes.
Topics: Adenosine; Animals; Cattle; Down-Regulation; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Isoflavones; Lymphocytes; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Suramin; Tetradecanoylphorbol Acetate; Theileria parva; Trypanocidal Agents; Type C Phospholipases | 1996 |
ATP depletion affects the phosphorylation state, ligand binding, and nuclear transport of the 4 S polycyclic aromatic hydrocarbon-binding protein in rat hepatoma cells.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Azides; Benzo(a)pyrene; Biological Transport; Carrier Proteins; Cell Compartmentation; Cell Nucleus; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytosol; Glycine N-Methyltransferase; Liver Neoplasms, Experimental; Methyltransferases; Okadaic Acid; Phosphoprotein Phosphatases; Rats; Staurosporine | 1996 |
The inhibitory effect of staurosporine on insulin action is prevented by okadaic acid. Evidence for an important role of serine/threonine phosphorylation in eliciting insulin-like effects.
Topics: Animals; Biological Transport; Enzyme Activation; Enzyme Inhibitors; Glucose; Insulin; Insulin Antagonists; Male; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinases; Protein Phosphatase 1; Rats; Receptor, Insulin; Serine; Staurosporine; Threonine; Tyrosine | 1996 |
Regulation of rat interstitial collagenase gene expression in growth cartilage and chondrocytes by vitamin D3, interleukin-1 beta, and okadaic acid.
Topics: Actins; Animals; Blotting, Northern; Carcinogens; Cartilage; Cells, Cultured; Cholecalciferol; Collagenases; Dactinomycin; DNA, Complementary; Electrophoresis, Agar Gel; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genes, Reporter; Interleukin-1; Male; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1996 |
Zinc enhancement of 17beta-estradiol's anabolic effect in osteoblastic MC3T3-E1 cells.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Carnosine; Cell Count; Cells, Cultured; Cycloheximide; DNA; Drug Synergism; Enzyme Inhibitors; Estradiol; Iron Chelating Agents; Mice; Okadaic Acid; Organometallic Compounds; Osteoblasts; Picolinic Acids; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Proteins; Staurosporine; Zinc; Zinc Compounds; Zinc Sulfate | 1997 |
Mechanism of beta-adrenergic agonist-induced transmural transport of glucose in rat small intestine. Regulation of phosphorylation of SGLT1 controls the function.
Topics: Adrenergic beta-Agonists; Animals; Biological Transport; Epinephrine; Glucose; In Vitro Techniques; Intestine, Small; Male; Membrane Glycoproteins; Monosaccharide Transport Proteins; Norepinephrine; Okadaic Acid; Ouabain; Phlorhizin; Phosphorylation; Rats; Rats, Wistar; Sodium-Glucose Transporter 1; Staurosporine; Vinblastine | 1997 |
Role of protein kinases in the in vitro differentiation of human epidermal HaCaT cells.
Topics: Adenine; Cell Differentiation; Cell Line; Enzyme Inhibitors; Epidermal Cells; Epidermis; Genistein; Humans; Indoles; Isoenzymes; Isoflavones; Keratinocytes; Maleimides; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Effects of inhibitors of signal transduction pathways on transforming growth factor beta1 and osteogenic protein-1-induced insulinlike growth factor binding protein-3 expression in human bone cells.
Topics: Bone and Bones; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Cells, Cultured; Culture Media, Conditioned; Gene Expression Regulation; Genistein; Humans; Insulin-Like Growth Factor Binding Protein 3; Isoflavones; Okadaic Acid; Osteoblasts; Phosphoprotein Phosphatases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Cells, Cultured; Vanadates | 1997 |
Kinase and phosphatase inhibitors cause rapid alterations in microtubule dynamic instability in living cells.
Topics: Animals; Cells, Cultured; Enzyme Inhibitors; Epithelium; Kinetin; Lung; Microscopy, Interference; Microtubules; Okadaic Acid; Phosphorylases; Phosphotransferases; Purines; Salamandridae; Staurosporine; Time Factors | 1997 |
Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriched in products of the NADPH oxidase complex. Evidence for a novel cycle of phosphorylation and dephosphorylation.
Topics: Actin Depolymerizing Factors; Actins; Amino Acid Sequence; Animals; Calcimycin; Cell Membrane; Diglycerides; Diterpenes; Guinea Pigs; Humans; Hydrogen Peroxide; Immunoblotting; Marine Toxins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Okadaic Acid; Oxazoles; Oxides; Phosphorylation; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate | 1997 |
Protein kinase inhibitors block neurite outgrowth from explants of goldfish retina.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Goldfish; Indole Alkaloids; Nerve Crush; Neurites; Okadaic Acid; Optic Nerve; Protein Kinase C; Protein Kinase Inhibitors; Retina; Sphingosine; Staurosporine | 1997 |
Modulation of rod photoreceptor cyclic nucleotide-gated channels by tyrosine phosphorylation.
Topics: Adenosine Triphosphate; Animals; Cyclic GMP; Enzyme Inhibitors; Eye Proteins; Hydroquinones; Ion Channel Gating; Marine Toxins; Microcystins; Okadaic Acid; Oocytes; Oxazoles; Patch-Clamp Techniques; Peptides, Cyclic; Phenols; Phosphorylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Rod Cell Outer Segment; Staurosporine; Vanadates; Xenopus laevis | 1997 |
Relocation of annexin V to platelet membranes is a phosphorylation-dependent process.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Annexin A5; Biological Transport; Blood Platelets; Calcimycin; Cell Compartmentation; Humans; Membranes; Okadaic Acid; Phosphoproteins; Phosphorylation; Platelet Activation; Protein Binding; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
G-protein activation, intracellular Ca2+ mobilization and phosphorylation studies of membrane currents induced by AlF4- in Xenopus oocytes.
Topics: Aluminum Compounds; Animals; Calcium; Cell Membrane; Electrophysiology; Fluorides; GTP-Binding Proteins; Okadaic Acid; Oocytes; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Signal Transduction; Staurosporine; Xenopus laevis | 1997 |
Facilitation of L-type calcium current in thalamic neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Electrophysiology; Enzyme Inhibitors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons; Okadaic Acid; omega-Conotoxin GVIA; omega-Conotoxins; Peptides; Rats; Staurosporine; Thalamic Nuclei; Thionucleotides; Time Factors | 1998 |
Stimulation of membrane serine-threonine phosphatase in erythrocytes by hydrogen peroxide and staurosporine.
Topics: Animals; Carrier Proteins; Cytosol; Enzyme Activation; Enzyme Inhibitors; Erythrocyte Membrane; Erythrocytes; Humans; Hydrogen Peroxide; In Vitro Techniques; K Cl- Cotransporters; Okadaic Acid; Phosphoprotein Phosphatases; Sheep; Staurosporine; Symporters | 1998 |
Inhibition of phosphorylation of the oxysterol binding protein by brefeldin A.
Topics: Animals; Brefeldin A; CHO Cells; Cricetinae; Cyclopentanes; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Golgi Apparatus; Hydroxycholesterols; Molecular Weight; Okadaic Acid; Phosphorylation; Protein Kinases; Protein Synthesis Inhibitors; Rabbits; Rats; Receptors, Steroid; Serine; Staurosporine | 1998 |
Streptozotocin-induced diabetes increases (Ca2+-Mg2+)-ATPase activity in hepatic plasma membranes of rats: involvement of protein kinase C.
Topics: Animals; Blood Glucose; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium-Binding Proteins; Carboxylic Ester Hydrolases; Cell Membrane; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Liver; Male; Okadaic Acid; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Sulfotransferases | 1998 |
Analysis of rotavirus nonstructural protein NSP5 phosphorylation.
Topics: Animals; Cell Line; COS Cells; Enzyme Inhibitors; Kinetics; Macaca mulatta; Okadaic Acid; Phosphorylation; Rotavirus; Staurosporine; Viral Proteins | 1998 |
Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.
Topics: Antineoplastic Agents; Apoptosis; CDC28 Protein Kinase, S cerevisiae; Cyclin B; Cyclin B1; Enzyme Activation; Enzyme Inhibitors; Female; Genistein; HeLa Cells; Humans; Mitosis; Nocodazole; Okadaic Acid; Paclitaxel; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Tumor Cells, Cultured | 1998 |
Reversible protein phosphorylation regulates jasmonic acid-dependent and -independent wound signal transduction pathways in Arabidopsis thaliana.
Topics: Arabidopsis; Cycloheximide; Cyclopentanes; Enzyme Inhibitors; Feedback; Gene Expression Regulation, Plant; Genes, Plant; Indoleacetic Acids; Models, Biological; Okadaic Acid; Oxylipins; Phosphoprotein Phosphatases; Phosphorylation; Plant Growth Regulators; Plant Proteins; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Staurosporine; Transcriptional Activation | 1998 |
PKC activity modulates availability and long openings of L-type Ca2+ channels in A7r5 cells.
Topics: Alkaloids; Animals; Aorta; Benzophenanthridines; Calcium Channels; Calcium Channels, L-Type; Cell Line; Enzyme Activation; Enzyme Inhibitors; Ion Channel Gating; Kinetics; Membrane Potentials; Muscle, Smooth, Vascular; Okadaic Acid; Patch-Clamp Techniques; Phenanthridines; Phorbol 12,13-Dibutyrate; Probability; Protein Kinase C; Rats; Staurosporine | 1998 |
Protein kinase C--catalyzed calponin phosphorylation in swine carotid arterial homogenate.
Topics: Animals; Antiemetics; Calcium; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Calmodulin-Binding Proteins; Calponins; Carcinogens; Carotid Arteries; Chelating Agents; Diglycerides; Egtazic Acid; Electrophoresis; Enzyme Inhibitors; Imidazoles; Microfilament Proteins; Okadaic Acid; Organ Culture Techniques; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phosphorus Radioisotopes; Phosphorylation; Protein Kinase C; Staurosporine; Sulfonamides; Swine; Trifluoperazine; Vasodilator Agents | 1998 |
Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Apoptosis; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Enzyme Inhibitors; Flavanones; Flavonoids; Genistein; Hippocampus; Indole Alkaloids; Male; Microscopy, Electron; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neurons; Okadaic Acid; Organ Culture Techniques; Phosphoric Monoester Hydrolases; Propidium; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Staurosporine; Sulfonamides | 1998 |
Entry into mitosis without Cdc2 kinase activation.
Topics: Animals; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Chromosomes; Enzyme Activation; Enzyme Inhibitors; G2 Phase; Lamins; Mammary Neoplasms, Experimental; Mice; Microtubules; Mitosis; Nuclear Envelope; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Staurosporine; Tumor Cells, Cultured | 1998 |
Expression of seizure-related PTZ-17 is induced by potassium deprivation in cerebellar granule cells.
Topics: Aging; Animals; Apoptosis; Cells, Cultured; Cerebellum; Dactinomycin; Nerve Tissue Proteins; Neurons; Okadaic Acid; Oncogene Proteins; Potassium Deficiency; Rats; Rats, Wistar; RNA, Messenger; Seizures; Staurosporine; Transcription, Genetic | 1998 |
Desensitization of ET(A) endothelin receptor-mediated negative chronotropic response in right atria--species difference and intracellular mechanisms.
Topics: Animals; Base Sequence; Endothelin Receptor Antagonists; Guinea Pigs; Heart Atria; Heart Rate; Male; Molecular Sequence Data; Okadaic Acid; Oligopeptides; Peptides, Cyclic; Phorbol Esters; Phosphorylation; Piperidines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Endothelin; Species Specificity; Staurosporine; Time Factors | 1998 |
Protein kinase inhibitors induce the interphase transition by inactivating mitogen-activated protein kinase in mouse eggs.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Genistein; Immunoblotting; Indoles; Interphase; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Okadaic Acid; Ovum; Protein-Tyrosine Kinases; Staurosporine | 1998 |
Transcriptional interferences between normal or mutant androgen receptors and the activator protein 1--dissection of the androgen receptor functional domains.
Topics: Aldehyde Reductase; Androgens; Animals; Breast Neoplasms, Male; COS Cells; DNA; Enzyme Inhibitors; Genes, Reporter; Genetic Engineering; Humans; Luciferases; Male; Marine Toxins; Mice; Mutation; Okadaic Acid; Oxazoles; Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Androgen; Staurosporine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection | 1999 |
Phosphorylation-mediated control of chromatin organization and transcriptional activity of the tissue-specific osteocalcin gene.
Topics: Animals; Chromatin; Deoxyribonuclease I; Enzyme Inhibitors; Gene Expression Regulation; Okadaic Acid; Osteocalcin; Phosphoprotein Phosphatases; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Rats; Staurosporine; Tumor Cells, Cultured; Vitamin D | 1999 |
Effect of catecholamines on the hyperpolarization-activated cationic Ih and the inwardly rectifying potassium I(Kir) currents in the rat substantia nigra pars compacta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cardiotonic Agents; Cations; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Agonists; Electric Conductivity; Enzyme Inhibitors; Male; Membrane Potentials; Neurons; Norepinephrine; Okadaic Acid; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Phosphorylation; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Protein Phosphatase 1; Quinpirole; Rats; Rats, Wistar; Staurosporine; Substantia Nigra; Sympathomimetics; Ventral Tegmental Area | 1999 |
Independent signal-transduction pathways for vanadate and for insulin in the activation of glycogen synthase and glycogenesis in rat adipocytes.
Topics: Adipocytes; Animals; Cytosol; Enzyme Activation; Enzyme Inhibitors; Glycogen; Glycogen Synthase; Insulin; Insulin Antagonists; Male; Okadaic Acid; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Vanadates | 1999 |
A role for phosphorylation in the dynamics of keratin intermediate filaments.
Topics: Adenine; Blotting, Western; Cell Line; Cytoskeleton; Densitometry; Fluorescent Antibody Technique; Intermediate Filaments; Keratins; Okadaic Acid; Phosphorylation; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 1999 |
Inhibition of atrial wall stretch-induced cardiac hormone secretion by lavendustin A, a potent tyrosine kinase inhibitor.
Topics: Animals; Atrial Function; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; In Vitro Techniques; Male; Myocardium; Myosin-Light-Chain Kinase; Natriuretic Peptide, Brain; Okadaic Acid; Phenols; Physical Stimulation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Staurosporine | 1999 |
P-glycoprotein phosphorylation/dephosphorylation and cellular accumulation of L-DOPA in LLC-GA5 Col300 cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Epithelium; Humans; Kidney; Levodopa; Okadaic Acid; Phorbols; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Staurosporine; Time Factors; Verapamil | 1999 |
Regulation of actin filament cross-linking and bundle shape in Drosophila bristles.
Topics: Actin Cytoskeleton; Actins; Animals; Carrier Proteins; Cell Membrane; Cross-Linking Reagents; Drosophila melanogaster; Drosophila Proteins; Enzyme Inhibitors; Insect Proteins; Microfilament Proteins; Okadaic Acid; Phosphorylation; Staurosporine; Time Factors | 2000 |
Selective loss of the transforming growth factor-beta apoptotic signaling pathway in mutant NRP-154 rat prostatic epithelial cells.
Topics: Animals; Apoptosis; bcl-X Protein; Cell Division; In Situ Nick-End Labeling; Male; Mutagenesis, Insertional; Okadaic Acid; Prostate; Proto-Oncogene Proteins c-bcl-2; Rats; Receptors, Transforming Growth Factor beta; Retroviridae; RNA, Messenger; Signal Transduction; Staurosporine; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured | 2000 |
Protein kinase and phosphatase modulation of quail brain GABA(A) and non-NMDA receptors co-expressed in Xenopus oocytes.
Topics: Animals; Brain Chemistry; Carcinogens; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Immunoblotting; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Okadaic Acid; Oocytes; Phorbol Esters; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinases; Quail; Receptors, GABA-A; Receptors, Kainic Acid; RNA, Messenger; Signal Transduction; Staurosporine; Vasodilator Agents; Xenopus | 2000 |
Protein phosphatase-protein kinase interplay modulates alpha 1b-adrenoceptor phosphorylation: effects of okadaic acid.
Topics: Animals; Antifungal Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indoles; Kinetics; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Pyrans; Pyrethrins; Rats; Receptors, Adrenergic, alpha-1; Spiro Compounds; Staurosporine; Tetradecanoylphorbol Acetate | 2000 |
Syringolin-mediated activation of the Pir7b esterase gene in rice cells is suppressed by phosphatase inhibitors.
Topics: Carbazoles; Cycloheximide; Enzyme Inhibitors; Esterases; Indole Alkaloids; Okadaic Acid; Oryza; Phosphoprotein Phosphatases; Phosphorylation; Plant Proteins; Protein Synthesis Inhibitors; RNA, Messenger; Signal Transduction; Staurosporine; Transcription, Genetic | 2000 |
Programmed cell death in 2',3'-dideoxycytidine-resistant human monoblastoid U937 cells.
Topics: Anti-HIV Agents; Apoptosis; DNA; Drug Resistance; Electrophoresis, Agar Gel; Enzyme Inhibitors; Glutathione; Humans; Molsidomine; Nitric Oxide Donors; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Staurosporine; U937 Cells; Zalcitabine | 2000 |
Augmentation of calcium current by hypoxia in carotid body glomus cells.
Topics: Animals; Buffers; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carotid Body; Cell Hypoxia; Cytosol; Enzyme Inhibitors; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Maleimides; Membrane Potentials; Nisoldipine; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Rabbits; Staurosporine | 2000 |
Estrogen directly acts on osteoclasts via inhibition of inward rectifier K+ channels.
Topics: Animals; Barium; Calcium; Cells, Cultured; Chelating Agents; Cyclic AMP; Dose-Response Relationship, Drug; Estradiol; Guanosine Diphosphate; Membrane Potentials; Okadaic Acid; Osteoclasts; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Progesterone; Rats; Rats, Wistar; Staurosporine; Testosterone; Tetradecanoylphorbol Acetate; Thionucleotides; Time Factors | 2000 |
Nitrate assimilation in chicory roots (Cichorium intybus L.) which acquire radial growth.
Topics: Blotting, Northern; Cichorium intybus; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Nitrate Reductase; Nitrate Reductases; Nitrates; Okadaic Acid; Phosphorylation; Plant Roots; Protein Processing, Post-Translational; RNA, Messenger; Staurosporine | 2000 |
Regulation of ANP-stimulated guanylate cyclase in the presence of Mn2+ in rat lung membranes.
Topics: Adenosine Triphosphate; Affinity Labels; Animals; Atrial Natriuretic Factor; Buffers; Enzyme Inhibitors; Guanylate Cyclase; Isoquinolines; Lung; Male; Manganese; Membranes; Okadaic Acid; Phosphates; Rats; Rats, Wistar; Receptors, Atrial Natriuretic Factor; Staurosporine; Vanadates | 2000 |
Screening of wound-responsive genes identifies an immediate-early expressed gene encoding a highly charged protein in mechanically wounded tobacco plants.
Topics: Amino Acid Sequence; Cycloheximide; Cytosol; DNA, Complementary; Egtazic Acid; Erythrosine; Gene Expression Regulation, Plant; Genes, Immediate-Early; Immediate-Early Proteins; Kinetics; Molecular Sequence Data; Molecular Weight; Nicotiana; Okadaic Acid; Plant Proteins; Plants, Toxic; Propionates; Sequence Homology, Amino Acid; Staurosporine; Time Factors; Transcription, Genetic | 2000 |
Two distinct mechanisms underlie the stimulation of neurotransmitter release by phorbol esters in clonal rat pheochromocytoma PC12 cells.
Topics: Acetylcholine; Animals; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Membrane Proteins; Microscopy, Fluorescence; Nerve Tissue Proteins; Okadaic Acid; PC12 Cells; Phorbol Esters; Phosphopeptides; Phosphorylation; Potassium; Protein Kinase C; Rats; Staurosporine; Synaptosomal-Associated Protein 25 | 2000 |
beta2-adaptin is constitutively de-phosphorylated by serine/threonine protein phosphatase PP2A and phosphorylated by a staurosporine-sensitive kinase.
Topics: Adaptor Protein Complex beta Subunits; Antifungal Agents; Cell Membrane; Cells, Cultured; Endocytosis; Enzyme Inhibitors; Humans; Jurkat Cells; Marine Toxins; Membrane Proteins; Microscopy, Confocal; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinases; Protein Phosphatase 2; Pyrans; Spiro Compounds; Staurosporine | 2000 |
Electrical activity regulates AChR gene expression via JNK, PKCzeta and Sp1 in skeletal chick muscle.
Topics: Activating Transcription Factor 2; Animals; Cells, Cultured; Chick Embryo; Cyclic AMP Response Element-Binding Protein; Electrophysiology; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Okadaic Acid; Phosphorylation; Protein Kinase C; Receptors, Nicotinic; Signal Transduction; Sp1 Transcription Factor; Staurosporine; Tetrodotoxin; Transcription Factors | 2001 |
Down-regulation of Na-K-Cl cotransport by protein kinase C is mediated by protein phosphatase 1 in pigmented ciliary epithelial cells.
Topics: Carcinogens; Cells, Cultured; Chloride Channels; Ciliary Body; Down-Regulation; Enzyme Inhibitors; Humans; Indoles; Maleimides; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Pigment Epithelium of Eye; Potassium Channels; Protein Kinase C; Protein Phosphatase 1; Rubidium Radioisotopes; Sodium Channels; Staurosporine; Tetradecanoylphorbol Acetate | 2001 |
Gab1 phosphorylation: a novel mechanism for negative regulation of HGF receptor signaling.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Communication; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Female; Hepatocyte Growth Factor; Humans; Isoenzymes; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Proto-Oncogene Proteins c-met; Serine; Signal Transduction; src Homology Domains; Staurosporine; Threonine | 2001 |
Changes in starch content in oat (Avena sativa) shoot pulvini during the gravitropic response.
Topics: Avena; Calcium Channel Blockers; Chloroplasts; Enzyme Inhibitors; Gravitropism; Lanthanum; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Plant Proteins; Plant Shoots; Signal Transduction; Starch; Staurosporine | 2001 |
Establishment of okadaic acid resistant cell clones using a cDNA expression library.
Topics: Amino Acid Sequence; Animals; Apoptosis; Base Sequence; Caspases; Cell Size; Clone Cells; Cloning, Molecular; Cytochrome c Group; Drug Resistance; Drug Resistance, Multiple; Enzyme Inhibitors; Fibroblasts; Gene Library; Humans; Jurkat Cells; Mice; Molecular Sequence Data; Okadaic Acid; Phenotype; Phosphoprotein Phosphatases; Phosphoproteins; Staurosporine; Transfection | 2001 |
Differential sensitivity of mesencephalic neurons to inhibition of phosphatase 2A.
Topics: Animals; Cell Count; Cells, Cultured; DNA Fragmentation; Dopamine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Immunohistochemistry; Injections; Male; Mesencephalon; Neostriatum; Neurons; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Staurosporine; Tyrosine 3-Monooxygenase | 2001 |
Effects of staurosporine, okadaic acid and sodium fluoride on protein phosphorylation in graviresponding oat shoot pulvini.
Topics: Avena; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gravitropism; Okadaic Acid; Phosphorylation; Plant Proteins; Plant Shoots; Pulvinus; Sodium Fluoride; Staurosporine | 2000 |
K-Cl cotransport modulation by intracellular Mg in erythrocytes from mice bred for low and high Mg levels.
Topics: Animals; Biological Transport; Carrier Proteins; Cations; Enzyme Inhibitors; Erythrocytes; Ethylmaleimide; K Cl- Cotransporters; Magnesium; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Okadaic Acid; Oxidation-Reduction; Phosphoprotein Phosphatases; Phosphorylation; Proto-Oncogene Proteins; Sodium-Potassium-Exchanging ATPase; Species Specificity; src-Family Kinases; Staurosporine; Symporters | 2001 |
Phosphorylation of native and heme-modified CYP3A4 by protein kinase C: a mass spectrometric characterization of the phosphorylated peptides.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Chromatography, Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Inhibitors; Heme; Humans; Kinetics; Liver; Mass Spectrometry; Mixed Function Oxygenases; Models, Molecular; Mutagenesis; Okadaic Acid; Peptide Fragments; Phenylalanine; Phosphopeptides; Phosphorylation; Protein Conformation; Protein Kinase C; Protein Structure, Secondary; Rats; Recombinant Proteins; Sequence Deletion; Serine; Staurosporine | 2001 |
Okadaic acid-sensitive activation of Maxi Cl(-) channels by triphenylethylene antioestrogens in C1300 mouse neuroblastoma cells.
Topics: Animals; Carcinogens; Chloride Channels; Chlorides; Cyclic AMP; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Ion Channel Gating; Mice; Neuroblastoma; Okadaic Acid; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Phosphorylation; Selective Estrogen Receptor Modulators; Signal Transduction; Staurosporine; Stilbenes; Tamoxifen; Toremifene; Tumor Cells, Cultured | 2001 |
Effect of Leishmania donovani lipophosphoglycan on ornithine decarboxylase activity in macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Bacterial Agents; Bucladesine; Calcimycin; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glycosphingolipids; Leishmania donovani; Leishmaniasis, Visceral; Lipopolysaccharides; Macrophages; Mice; Okadaic Acid; Ornithine Decarboxylase; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Modulation of microglial superoxide production by alpha-tocopherol in vitro: attenuation of p67(phox) translocation by a protein phosphatase-dependent pathway.
Topics: alpha-Tocopherol; Animals; Antioxidants; Cell Membrane; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Marine Toxins; Mice; Microglia; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nerve Tissue Proteins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Transport; Rats; Respiratory Burst; Staurosporine; Superoxides; Swine | 2001 |
Inhibition of protein phosphatase-1 is linked to phosphorylation of p53 and apoptosis.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Apoptosis; Blotting, Western; Catalytic Domain; DNA; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Macrolides; Male; Myocardium; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Protein Phosphatase 1; Protein Subunits; Rats; Rats, Wistar; Staurosporine; Trypsin; Tumor Suppressor Protein p53 | 2002 |
Fusion genetic analysis of jasmonate-signalling mutants in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Cyclopentanes; Escherichia coli; Gene Expression Regulation; Glucuronidase; Lipoxygenase; Luciferases; Luminescent Measurements; Mutation; Okadaic Acid; Oxylipins; Phenotype; Phosphoric Monoester Hydrolases; Plant Growth Regulators; Plant Proteins; Plants, Genetically Modified; Promoter Regions, Genetic; Protein Kinase Inhibitors; Protein Kinases; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction; Staurosporine | 2002 |
Cell cycle-dependent regulation of telomerase activity by auxin, abscisic acid and protein phosphorylation in tobacco BY-2 suspension culture cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2,4-Dichlorophenoxyacetic Acid; Abscisic Acid; Cantharidin; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Indoleacetic Acids; Nicotiana; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Plant Growth Regulators; Protein Phosphatase 2; Staurosporine; Telomerase; Telomere; Time Factors | 2002 |
Phosphorylation of the salivary Na(+)-K(+)-2Cl(-) cotransporter.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indole Alkaloids; Indoles; Isoproterenol; Isoquinolines; Maleimides; Marine Toxins; Microcystins; Okadaic Acid; Oxazoles; Parotid Gland; Peptides, Cyclic; Phenols; Phosphorus Radioisotopes; Phosphorylation; Rats; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Staurosporine; Sulfonamides; Sympathomimetics; Vanadates | 2002 |
Mechanically stimulated TCH3 gene expression in Arabidopsis involves protein phosphorylation and EIN6 downstream of calcium.
Topics: Arabidopsis; Arabidopsis Proteins; Calcium; Calcium-Binding Proteins; Dimethyl Sulfoxide; Gene Expression Regulation, Plant; Marine Toxins; Mutation; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Plant Proteins; Protein Kinase Inhibitors; Receptors, Cell Surface; Signal Transduction; Staurosporine; Stress, Mechanical | 2002 |
Hyperosmotic stimuli inhibit VCAM-1 expression in cultured endothelial cells via effects on interferon regulatory factor-1 expression and activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Membrane; Cells, Cultured; Culture Media; Cycloheximide; DNA-Binding Proteins; E-Selectin; Endothelium, Vascular; Gene Expression Regulation; GTP-Binding Proteins; Imidazoles; Intercellular Adhesion Molecule-1; Interferon Regulatory Factor-1; Interferon-gamma; Interferon-Stimulated Gene Factor 3; Interleukin-1; Interleukin-13; Interleukin-4; NF-kappa B; Okadaic Acid; Osmosis; Phosphoproteins; Promoter Regions, Genetic; Pyridines; RNA, Messenger; Staurosporine; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2002 |
Light signalling mediated by phytochrome plays an important role in cold-induced gene expression through the C-repeat/dehydration responsive element (C/DRE) in Arabidopsis thaliana.
Topics: Abscisic Acid; Acclimatization; Arabidopsis; Arabidopsis Proteins; Cold Temperature; Darkness; Disasters; Diuron; DNA-Binding Proteins; Gene Expression Regulation; Light; Mutation; Okadaic Acid; Phosphoprotein Phosphatases; Photoreceptor Cells; Phytochrome; Phytochrome B; Plants, Genetically Modified; Protein Phosphatase 2; Signal Transduction; Sodium Chloride; Staurosporine; Trans-Activators; Transcription Factors | 2002 |
Characterization of early, chitin-induced gene expression in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Carbazoles; Chitin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Plant; Indole Alkaloids; Lectins; Marine Toxins; Mitogen-Activated Protein Kinase Kinases; Okadaic Acid; Oligosaccharides; Oxazoles; Phosphorylation; Plant Proteins; RNA, Messenger; Signal Transduction; Staurosporine; Transcriptional Activation; Zinc Fingers | 2002 |
Phorbol ester stimulates a protein kinase C-mediated agatoxin-TK-sensitive calcium permeability pathway in human red blood cells.
Topics: Adult; Agatoxins; Alkaloids; Benzophenanthridines; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Signaling; Cell Size; Diglycerides; Dimethyl Sulfoxide; Enzyme Inhibitors; Erythrocytes; Humans; Ion Transport; Ionophores; Marine Toxins; Okadaic Acid; Osmotic Fragility; Oxazoles; Phenanthridines; Phosphoprotein Phosphatases; Protein Kinase C; Spider Venoms; Staurosporine; Tetradecanoylphorbol Acetate | 2002 |
Nuclear localisation of cytosolic phospholipase A2-alpha in the EA.hy.926 human endothelial cell line is proliferation dependent and modulated by phosphorylation.
Topics: Amino Acid Sequence; Cell Count; Cell Division; Cell Line; Cell Nucleus; Cytosol; Fatty Acids, Unsaturated; Flavonoids; Gene Expression Regulation, Enzymologic; Group IV Phospholipases A2; Humans; Imidazoles; Lectins; Models, Molecular; Molecular Sequence Data; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Conformation; Protein Transport; Pyridines; Staurosporine | 2002 |
Protein kinase antagonists inhibit invasion of mammalian cells by Fonsecaea pedrosoi.
Topics: Animals; Cell Adhesion; CHO Cells; Cricetinae; Drug Interactions; Enzyme Inhibitors; Fungi; Genistein; Naphthalenes; Okadaic Acid; Protein Kinase Inhibitors; Staurosporine | 2003 |
Prolactin signalling in porcine theca cells: the involvement of protein kinases and phosphatases.
Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Female; Genistein; Inositol Phosphates; Kinetics; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Progesterone; Prolactin; Protein Kinase C; Protein Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Swine; Theca Cells; Vanadates | 2003 |
Effects of Ca(2+) channel blockers and protein kinase/phosphatase inhibitors on growth and anthraquinone production in Rubia cordifolia callus cultures transformed by the rolB and rolC genes.
Topics: Anthraquinones; beta-Glucosidase; Calcium; Calcium Channel Blockers; Cantharidin; Carrier Proteins; Culture Techniques; Intracellular Signaling Peptides and Proteins; Okadaic Acid; Oncogene Proteins; Onium Compounds; Phenotype; Phosphoprotein Phosphatases; Plant Proteins; Plants, Genetically Modified; Rubia; Staurosporine | 2003 |
Protein phosphatase 1 and an opposing protein kinase regulate steady-state L-type Ca2+ current in mouse cardiac myocytes.
Topics: Animals; Biophysical Phenomena; Biophysics; Buffers; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Electric Conductivity; Enzyme Inhibitors; Homeostasis; Isoenzymes; Male; Marine Toxins; Mice; Mice, Inbred Strains; Myocytes, Cardiac; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Protein Kinase C; Protein Phosphatase 1; Staurosporine; Thionucleotides | 2004 |
Arabidopsis RAV1 is down-regulated by brassinosteroid and may act as a negative regulator during plant development.
Topics: 2,4-Dichlorophenoxyacetic Acid; Arabidopsis; Arabidopsis Proteins; Blotting, Northern; Blotting, Southern; Blotting, Western; Brassinosteroids; Cholestanols; Cycloheximide; DNA-Binding Proteins; DNA, Antisense; Down-Regulation; Flowers; Gene Dosage; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Models, Biological; Mutation; Okadaic Acid; Oligonucleotide Array Sequence Analysis; Plant Growth Regulators; Plant Leaves; Plant Roots; Plants, Genetically Modified; Protein Kinases; Rhizobium; Signal Transduction; Staurosporine; Steroids, Heterocyclic; Transformation, Genetic; Zeatin | 2004 |
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate | 2004 |
Bidirectional regulation of renal cortical Na+,K+-ATPase by protein kinase C.
Topics: Amiloride; Animals; Arachidonic Acids; Brefeldin A; Cytochrome P-450 Enzyme System; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Kidney Cortex; Kinetics; Male; Models, Biological; Nocodazole; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositol 3-Kinases; Protein Kinase C; Rats; Rats, Wistar; Sodium; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate | 2004 |
Linking alterations in tau phosphorylation and cleavage during neuronal apoptosis.
Topics: Alzheimer Disease; Animals; Apoptosis; Caspase Inhibitors; Cells, Cultured; Cerebral Cortex; Colchicine; Embryo, Mammalian; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lithium; Neurons; Okadaic Acid; Peptide Fragments; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; Staurosporine; tau Proteins | 2004 |
Volatile C6-aldehydes and Allo-ocimene activate defense genes and induce resistance against Botrytis cinerea in Arabidopsis thaliana.
Topics: Acyclic Monoterpenes; Aldehydes; Arabidopsis; Arabidopsis Proteins; Botrytis; Gene Expression Regulation, Plant; Genes, Plant; Nucleotidyltransferases; Okadaic Acid; Plant Diseases; Polyenes; Receptors, Cell Surface; Staurosporine; Time Factors; Volatilization | 2005 |
Augmenting effect of serotonin on the voltage-dependent Ca2+ current and subsequently activated K+ current in Aplysia neurons.
Topics: Animals; Aplysia; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Cholera Toxin; Enzyme Inhibitors; Guanosine Diphosphate; Large-Conductance Calcium-Activated Potassium Channels; Neurons; Okadaic Acid; Patch-Clamp Techniques; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Potassium Channels, Calcium-Activated; Protein Kinase C; Receptors, Serotonin; Serotonin; Signal Transduction; Staurosporine; Tetraethylammonium; Thionucleotides | 2007 |
Signalling pathways involved in the control of sperm cell volume.
Topics: Animals; Cell Size; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indoles; Ion Channels; Male; Maleimides; Marine Toxins; Okadaic Acid; Osmosis; Oxazoles; Papaverine; Phosphoprotein Phosphatases; Protein Kinase C; Signal Transduction; Spermatozoa; Staurosporine; Swine | 2007 |
Synaptic vesicle mobility in mouse motor nerve terminals with and without synapsin.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Egtazic Acid; Enzyme Inhibitors; Fluorescence Recovery After Photobleaching; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Neurons; Okadaic Acid; Organ Culture Techniques; Phosphoric Monoester Hydrolases; Phosphotransferases; Presynaptic Terminals; Pyridinium Compounds; Quaternary Ammonium Compounds; Staurosporine; Synapsins; Synaptic Vesicles; Temperature; Thiazolidines | 2007 |
Attenuation of hypoosmotic stress-induced ANP secretion via I(Cl,swell) in renal hypertensive rat atria.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Atrial Natriuretic Factor; Cardiomegaly; Chloride Channels; Estrenes; Extracellular Fluid; Genistein; Heart Atria; Hypertension, Renal; Indoles; Maleimides; Okadaic Acid; Osmotic Pressure; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Staurosporine; Tamoxifen; Vanadates | 2008 |
Apoptotic endothelial cells demonstrate increased adhesiveness for human mesenchymal stem cells.
Topics: Androstadienes; Animals; Antigens, Surface; Apoptosis; Cell Adhesion; Cells, Cultured; Cycloheximide; Endothelial Cells; Enzyme Inhibitors; Humans; Interleukin-1beta; Membrane Potential, Mitochondrial; Mesenchymal Stem Cells; NADH Dehydrogenase; Okadaic Acid; Protein Synthesis Inhibitors; Signal Transduction; Staurosporine; Tumor Necrosis Factor-alpha; von Willebrand Factor; Wortmannin | 2009 |
The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms.
Topics: 4-Butyrolactone; beta Catenin; Caco-2 Cells; Cadherins; Cytoplasm; Epithelial Cells; Genistein; Homoserine; Humans; Intercellular Junctions; Membrane Proteins; Occludin; Okadaic Acid; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Pseudomonas aeruginosa; Quorum Sensing; Staurosporine; Zonula Occludens-1 Protein | 2009 |
An impedimetric microelectrode-based array sensor for label-free detection of tau hyperphosphorylation in human cells.
Topics: Analysis of Variance; Carbazoles; Cell Line, Tumor; Electric Impedance; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Laminin; Microchip Analytical Procedures; Microelectrodes; Neuroblastoma; Okadaic Acid; Phosphorylation; Staurosporine; tau Proteins | 2009 |
Regulation of K-Cl cotransport in erythrocytes of frog Rana temporaria by commonly used protein kinase and protein phosphatase inhibitors.
Topics: Animals; Benzophenanthridines; Biological Transport; Enzyme Inhibitors; Erythrocytes; Fluorides; Genistein; K Cl- Cotransporters; Okadaic Acid; Ouabain; Phosphoprotein Phosphatases; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quercetin; Rana temporaria; Staurosporine; Symporters; Tyrphostins | 2010 |
Encystation process of Giardia lamblia: morphological and regulatory aspects.
Topics: Androstadienes; Chromones; Culture Media; Enzyme Inhibitors; Genistein; Giardia lamblia; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Morpholines; Okadaic Acid; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein-Tyrosine Kinases; Protozoan Proteins; Staurosporine; Wortmannin | 2010 |
Immunoregulatory potential of marine algal toxins yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4.
Topics: Adjuvants, Immunologic; Animals; CD3 Complex; Cell Line; Flow Cytometry; Mice; Mollusk Venoms; Okadaic Acid; Oxocins; Protein Kinase C; Receptor-CD3 Complex, Antigen, T-Cell; Staurosporine; T-Lymphocytes | 2011 |
MicroR828 regulates lignin and H2O2 accumulation in sweet potato on wounding.
Topics: Acetates; Agrobacterium; Antioxidants; Base Sequence; Calcium; Cyclic ADP-Ribose; Cyclic GMP; Cyclopentanes; Ethylenes; Gene Expression Profiling; Gene Expression Regulation, Plant; Hydrogen Peroxide; Ipomoea batatas; Lignin; MicroRNAs; Molecular Sequence Data; Niacinamide; Nitric Oxide; Okadaic Acid; Oxylipins; Phosphoprotein Phosphatases; Plant Proteins; Plants, Genetically Modified; Propanols; Protein Kinases; RNA, Messenger; Staurosporine; Stress, Mechanical | 2012 |
Apaf-1- and Caspase-8-independent apoptosis.
Topics: Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase 8; Caspase 9; Cells, Cultured; Fibroblasts; Isoquinolines; Mice; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Protein Kinase Inhibitors; Staurosporine; Sulfonamides; Thymocytes | 2013 |
Na+/H+ exchanger 1 is regulated via its lipid-interacting domain, which functions as a molecular switch: a pharmacological approach using indolocarbazole compounds.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Binding, Competitive; Carbazoles; Cation Transport Proteins; Cell Membrane; Cricetinae; Cricetulus; Databases, Chemical; Indoles; Lipids; Maleimides; Mice; Mutation; Okadaic Acid; Osmotic Pressure; Phosphatidylinositol 4,5-Diphosphate; Protein Kinase C; Protein Kinase Inhibitors; Protein Structure, Tertiary; Protein Transport; Receptors, Adrenergic, alpha-1; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Staurosporine; Transfection | 2014 |