staurosporine and n-methylaspartate

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Colforsin; Diterpenes; Enzyme Activation; Female; Genetic Variation; Kinetics; Ligands; Molecular Sequence Data; N-Methylaspartate; Oligodeoxyribonucleotides; Oocytes; Polyamines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, N-Methyl-D-Aspartate; RNA Splicing; Sphingosine; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Xenopus laevis

Topics: Alkaloids; Animals; Aspartic Acid; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebellum; Dendrites; Enzyme Inhibitors; N-Methylaspartate; Protein Kinase C; Rats; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate

Topics: Alkaloids; Amino Acid Oxidoreductases; Analysis of Variance; Animals; Corpus Striatum; Dizocilpine Maleate; Hydroxyl Radical; Male; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Protein Kinase C; Rats; Receptors, N-Methyl-D-Aspartate; Staurosporine

Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Drug Synergism; Female; Hippocampus; In Vitro Techniques; N-Methylaspartate; Protein Kinase C; Rats; Receptors, Muscarinic; Staurosporine; Terpenes; Tetrodotoxin; Thapsigargin

Topics: Alkaloids; Animals; Calcium; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Enzyme Activation; Glycine; Intracellular Fluid; Kinetics; Magnesium Sulfate; N-Methylaspartate; Naphthalenes; Neurons; Pipecolic Acids; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Staurosporine; Tetradecanoylphorbol Acetate

Topics: Alkaloids; Animals; Animals, Newborn; Bradykinin; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; In Vitro Techniques; Kinetics; N-Methylaspartate; Neurokinin A; Protease Inhibitors; Protein Kinase C; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Staurosporine; Substance P; Time Factors

Topics: Alkaloids; Animals; Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kainic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Degeneration; Neurons; Staurosporine; Time Factors

Topics: Aging; Alkaloids; Animals; Cerebral Cortex; Electrophysiology; In Situ Hybridization; Male; N-Methylaspartate; Protein Kinase C; Rats; Rats, Inbred F344; Receptors, Serotonin; Serotonin; Signal Transduction; Staurosporine

Topics: Alkaloids; Animals; Biological Transport; Calcium; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Potassium Chloride; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides

Topics: Alkaloids; Animals; Carbachol; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dopamine; Drug Synergism; Fetus; Isoquinolines; Kainic Acid; Kinetics; Mesencephalon; N-Methylaspartate; Neurons; Oxotremorine; Protein Kinase C; Quisqualic Acid; Rats; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems; Staurosporine

Topics: Alkaloids; Amphetamines; Animals; Calmodulin; Carbachol; Cerebral Cortex; Concanavalin A; Drug Interactions; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Phenylephrine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Staurosporine

Topics: Animals; Cells, Cultured; Cerebellum; Cyclic GMP; Down-Regulation; Enzyme Inhibitors; N-Methylaspartate; NADP; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Protein Kinase C; Rats; Rats, Wistar; Staurosporine

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides

Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; Calcium; Carcinogens; Cell Death; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Fetus; Gene Expression; Glutamic Acid; Kainic Acid; Membrane Proteins; N-Methylaspartate; Naphthalenes; Neurons; Phenanthridines; Potassium Chloride; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Staurosporine; Tetradecanoylphorbol Acetate

Topics: Amyloid beta-Peptides; Animals; Calcium; Calpain; Caspase 1; Cell Death; Cells, Cultured; Cysteine Endopeptidases; DNA Fragmentation; Endopeptidases; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Interleukin-1; N-Methylaspartate; Neurotoxins; Peptide Fragments; Pregnancy; Pyramidal Cells; Rats; Staurosporine

Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Benzopyrans; Calcium; Cerebral Cortex; Cromakalim; Cycloheximide; Cysteine Proteinase Inhibitors; Gadolinium; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Nifedipine; Patch-Clamp Techniques; Potassium; Potassium Channels; Pyrroles; Staurosporine; Tetraethylammonium; Tetraethylammonium Compounds; Veratridine

Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Cerebral Cortex; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Membrane Potentials; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Phosphorylation; Pregnancy; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Staurosporine

Topics: Adenosine Triphosphate; Androstadienes; Animals; Apoptosis; Buthionine Sulfoximine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Flavonoids; Hypoglycemic Agents; Insulin; Insulin Antagonists; Insulin-Like Growth Factor I; Iron; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; N-Methylaspartate; Necrosis; Neocortex; Neurons; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorus Radioisotopes; Phosphorylation; Staurosporine; Wortmannin

Topics: Amino Acids; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cerebral Cortex; DNA Fragmentation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gerbillinae; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neuroprotective Agents; Rats; Staurosporine

Topics: Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Cells, Cultured; Chelating Agents; Chlorides; Chromans; Estradiol; Estrogens; Estrone; Ethylenediamines; Excitatory Amino Acid Agonists; Ferric Compounds; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neurons; Organ of Corti; Peptide Fragments; Staurosporine

Topics: Alzheimer Disease; Animals; Animals, Newborn; Antibodies; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Apoptosis; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; Humans; Hypoxia-Ischemia, Brain; In Vitro Techniques; Mice; Mice, Inbred CBA; Mice, Knockout; N-Methylaspartate; Neurons; Neurotoxins; Staurosporine

Topics: Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cerebral Cortex; Drug Interactions; N-Methylaspartate; Neuroglia; Neurons; Rats; Staurosporine; Time Factors

Topics: Alkaloids; Animals; Animals, Newborn; Anions; Benzophenanthridines; Cerebral Arteries; Cerebrovascular Circulation; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Free Radicals; Hypoxia-Ischemia, Brain; Indicators and Reagents; Male; N-Methylaspartate; Nitroblue Tetrazolium; Nociceptin; Opioid Peptides; Peptide Fragments; Phenanthridines; Pia Mater; Protein Kinase C; Staurosporine; Superoxide Dismutase; Superoxides; Swine; Vasodilation; Vasodilator Agents

Topics: Animals; Apoptosis; Calcitonin; Cell Death; Cells, Cultured; Culture Media, Serum-Free; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glucose; Hypoxia-Ischemia, Brain; Kainic Acid; Mice; N-Methylaspartate; Necrosis; Neurons; Oxygen; Receptors, AMPA; Salmon; Staurosporine

Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Aspirin; Benzoates; Calcium; Calcium Channels, N-Type; Cerebral Cortex; Chromans; Excitatory Amino Acid Agonists; Ion Channel Gating; Ion Transport; Membrane Potentials; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; omega-Conotoxin GVIA; omega-Conotoxins; Staurosporine; Structure-Activity Relationship; Zinc

Topics: Amino Acid Chloromethyl Ketones; Animals; Caspase Inhibitors; Cell Cycle Proteins; Cell Death; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; GPI-Linked Proteins; Humans; Membrane Proteins; N-Methylaspartate; Neuroblastoma; Neurons; Neurotoxins; Proto-Oncogene Proteins c-bcl-2; Rats; Resting Phase, Cell Cycle; RNA, Antisense; RNA, Messenger; Staurosporine; Tumor Cells, Cultured

Topics: Acidosis; Apoptosis; Caspase Inhibitors; Cell Death; Cell Hypoxia; Cell Line; Cell Nucleus; Cell Survival; Culture Media; DNA Fragmentation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Free Radicals; Glucose; Humans; Hydrogen-Ion Concentration; N-Methylaspartate; Necrosis; Neurons; Oxygen; Poly(ADP-ribose) Polymerases; Staurosporine

Topics: Agmatine; Animals; Calcimycin; Cell Death; Cerebral Cortex; Enzyme Inhibitors; Fetus; Glutamic Acid; Ionophores; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; PC12 Cells; Protein Kinase Inhibitors; Protein Kinases; Rats; Staurosporine

Topics: Animals; Calcium; Catalase; Cell Death; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electrophysiology; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorometry; Free Radical Scavengers; Fura-2; Hippocampus; Immunohistochemistry; Membrane Potentials; Metalloporphyrins; Mitochondria; N-Methylaspartate; Oligonucleotides, Antisense; Oxygen; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Channels; Staurosporine; Superoxides; Tetrodotoxin; Time Factors; Tumor Suppressor Protein p53; Veratridine; Vitamin E

Topics: Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Embryo, Mammalian; Enzyme Inhibitors; Estrone; Hippocampus; L-Lactate Dehydrogenase; N-Methylaspartate; Neocortex; Neurons; Rats; Rats, Wistar; Staurosporine; Time Factors

Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Caspases; Cells, Cultured; Cerebral Cortex; Fetus; Flavoproteins; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Protein C; Receptor, PAR-1; Receptors, Thrombin; Staurosporine; Tumor Suppressor Protein p53

Topics: Animals; Arsenicals; Cell Line; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; Genistein; Glycine; Humans; N-Methylaspartate; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor Cross-Talk; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Resorcinols; Staurosporine; Thapsigargin; Transfection; Tyrosine; Vanadates

Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Brain Ischemia; Caspases; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glucose; Models, Biological; N-Methylaspartate; Neurons; Oligopeptides; Oxygen; Rats; Rats, Sprague-Dawley; Staurosporine; Time Factors

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Ergolines; Excitatory Amino Acid Antagonists; Gallopamil; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Indoles; Magnesium; Memantine; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nifedipine; Protein Kinase C; Pyridines; Rana pipiens; Receptor, Serotonin, 5-HT2B; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Staurosporine; Sulfonamides; Tetrodotoxin

Topics: Animals; Apoptosis; Benzimidazoles; Caspase 3; Caspases; Cells, Cultured; Cytochromes c; Drug Resistance; Drug Synergism; Excitatory Amino Acid Agonists; Hippocampus; L-Lactate Dehydrogenase; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; N-Methylaspartate; Neocortex; Neurons; Receptors, N-Methyl-D-Aspartate; Staurosporine; Telencephalon; Up-Regulation

Topics: Animals; Apoptosis; Caffeine; Caspase 3; Caspases; Chromosomes, Artificial, Yeast; Humans; Huntingtin Protein; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neurotoxins; Nuclear Proteins; Recombinant Proteins; Staurosporine

Topics: Animals; Blotting, Northern; Blotting, Western; Brain; Cell Death; Cells, Cultured; Culture Media, Conditioned; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; High Mobility Group Proteins; HMGB1 Protein; Infarction, Middle Cerebral Artery; Inflammation; Male; Mice; Microglia; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Time Factors; Transfection

Topics: Active Transport, Cell Nucleus; Animals; Brain; Caspase 6; Caspases; Cell Nucleus; Humans; Huntingtin Protein; Huntington Disease; Hydrolysis; Mice; Mice, Transgenic; Mutation; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Quinolinic Acid; Staurosporine

Topics: Animals; Apoptosis; Blotting, Western; Brain Injuries; Caspases; Cells, Cultured; Cerebral Cortex; Cytochromes c; Disease Models, Animal; Embryo, Mammalian; Enzyme Inhibitors; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Molsidomine; N-Methylaspartate; Neural Inhibition; Neurons; Nitric Oxide Donors; Peroxynitrous Acid; Physical Stimulation; Rats; Rats, Sprague-Dawley; Staurosporine

Topics: Animals; Apoptosis; Calcium; Cell Survival; Humans; Mice; Mice, Transgenic; N-Methylaspartate; Staurosporine; Telomerase; Telomere

Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Death; Cerebral Cortex; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Excitatory Amino Acids; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Neurotransmitter Agents; Phosphoinositide-3 Kinase Inhibitors; Pregnanolone; Pregnenolone; Reactive Oxygen Species; Staurosporine; Steroids

Topics: Animals; Animals, Newborn; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cerebellum; Humans; Isoquinolines; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Methylaspartate; Neurons; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Potassium; Proto-Oncogene Proteins c-akt; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Staurosporine

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Kainic Acid; Mice; Mitogen-Activated Protein Kinases; N-Methylaspartate; Necrosis; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Pregnancy; Proto-Oncogene Proteins c-akt; Quisqualic Acid; Staurosporine; Thyrotropin-Releasing Hormone

Topics: Animals; Apoptosis; Biomarkers; Brain Injuries; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Glial Fibrillary Acidic Protein; Marine Toxins; Mass Spectrometry; N-Methylaspartate; Necrosis; Neuroglia; Neurons; Oxocins; Protein Interaction Maps; Proteomics; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Ubiquitin Thiolesterase

Topics: Animals; Calcimycin; Calpain; Cells, Cultured; Chromatography, Liquid; Marine Toxins; Mice; Mice, Transgenic; Molecular Weight; N-Methylaspartate; Nanotechnology; Neurons; Oxocins; Peptides; Phosphorylation; Primary Cell Culture; Proteolysis; Rats; Spectrometry, Mass, Electrospray Ionization; Staurosporine; Tandem Mass Spectrometry; tau Proteins