staurosporine has been researched along with kn 62 in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (66.67) | 18.2507 |
| 2000's | 7 (25.93) | 29.6817 |
| 2010's | 2 (7.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
| Terrian, DM; Ways, DK | 1 |
| Onozuka, M; Watanabe, K | 1 |
| Emerling, D; Hashimoto, Y; Horie, Y; Kinoshita, M; Kurokawa, K; Nakao, A; Tsukamoto, K; Watanabe, T | 1 |
| Bers, DM; Yuan, W | 1 |
| Kimura, I; Kimura, M; Nojima, H | 1 |
| Boniece, IR; Maiese, K; Skurat, K; Wagner, JA | 1 |
| Maurer, JA; McKay, DB; Wenger, BW | 1 |
| Rothstein, TL; Wang, Z; Xie, H | 1 |
| Chock, PB; Huang, CY; Tekle, E; Zhu, DM | 1 |
| Moreland, RS; Rokolya, A; Walsh, MP | 1 |
| Frindt, G; Palmer, LG; Windhager, EE | 1 |
| Ruskoaho, H; Taskinen, P; Toth, M | 1 |
| Fukunaga, K; Kano, M; Konnerth, A | 1 |
| Puschner, B; Schacht, J | 1 |
| Haug, FM; Laake, JH; Ottersen, OP; Rundén, E; Seglen, PO; Shamloo, M; Wieloch, T | 1 |
| Huh, SO; Kim, YH; Lee, JK; Lee, KJ; Song, DK; Suh, HW; Won, JS | 1 |
| Diener, M; Heinke, B; Ribeiro, R | 1 |
| Greger, R; Henger, A; Mundel, P; Nitschke, R; Pavenstädt, H; Rüdiger, F | 1 |
| Ardenghi, P; Barros, DM; Izquierdo, I; Izquierdo, LA; Medinam, JH; Mello e Souza, T; Rodrigues, C; Sant'Anna, MK; Vianna, M | 1 |
| Bhattacharya, A; Chandok, MR; Deswal, R; Pandey, GK; Sopory, SK; Yadav, N | 1 |
| Davis, J; Schiebinger, R; Yingst, DR | 1 |
| Hermans, E; Maloteaux, JM; Najimi, M; Page, G; Peeters, M | 1 |
| Beauchemin, N; Fournès, B; Létourneau, S; Sadekova, S; Turbide, C | 1 |
| Hackman, JC; Holohean, AM | 1 |
| Liu, Y; Randall, WR; Schneider, MF | 1 |
| Ayalew, S; Chintagari, NR; Hartson, SD; Liu, L; Mishra, A; Su, L; Wang, Y | 1 |
27 other study(ies) available for staurosporine and kn 62
| Article | Year |
|---|---|
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |
Persistent enhancement of sustained calcium-dependent glutamate release by phorbol esters: role of calmodulin-independent serine/threonine phosphorylation and actin disassembly.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Alkaloids; Animals; Barium; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cytochalasin D; Ethers, Cyclic; Glutamates; Guinea Pigs; Hippocampus; Isoquinolines; Male; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Phosphotransferases; Piperazines; Protein Kinase C; Serine; Sphingosine; Staurosporine; Subcellular Fractions; Sulfonamides; Synaptosomes; Threonine | 1995 |
Glutamate elicits an outward K+ current which is normally suppressed by a Ca2+/calmodulin-dependent protein kinase II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alkaloids; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cholera Toxin; Dose-Response Relationship, Drug; Ganglia, Invertebrate; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kynurenic Acid; Membrane Potentials; Neurons; Pertussis Toxin; Piperazines; Potassium Channels; Protein Kinase Inhibitors; Snails; Staurosporine; Sulfonamides; Time Factors; Virulence Factors, Bordetella | 1994 |
Prostaglandin F2 alpha enhances tyrosine phosphorylation and DNA synthesis through phospholipase C-coupled receptor via Ca(2+)-dependent intracellular pathway in NIH-3T3 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Calcium; Dinoprost; DNA; Ionomycin; Isoquinolines; Mice; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Receptors, Prostaglandin; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Type C Phospholipases; Tyrosine | 1994 |
Ca-dependent facilitation of cardiac Ca current is due to Ca-calmodulin-dependent protein kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Alkaloids; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Electric Conductivity; Ferrets; Heart; Heart Ventricles; Isoquinolines; Myocardium; Peptide Fragments; Piperazines; Rabbits; Staurosporine; Sulfonamides | 1994 |
The evidence of accelerative interaction between cAMP-dependent protein kinase and external calcium for the desensitization of nicotinic acetylcholine receptor channel in mouse skeletal muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Hydroxybenzoates; Isoquinolines; Mice; Muscles; Piperazines; Receptors, Nicotinic; Staurosporine; Sulfonamides; Time Factors | 1994 |
Protein kinases modulate the sensitivity of hippocampal neurons to nitric oxide toxicity and anoxia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bucladesine; Cell Death; Cell Hypoxia; Cells, Cultured; Dibutyryl Cyclic GMP; Hippocampus; Isoquinolines; Nerve Tissue Proteins; Nitric Oxide; Phorbol Esters; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sphingosine; Staurosporine; Sulfonamides | 1993 |
Effects of protein kinase inhibitors on morphology and function of cultured bovine adrenal chromaffin cells: KN-62 inhibits secretory function by blocking stimulated Ca2+ entry.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Medulla; Alkaloids; Animals; Benzophenanthridines; Biological Transport; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Catecholamines; Cattle; Cells, Cultured; Enzyme Inhibitors; Indole Alkaloids; Isoquinolines; Phenanthridines; Piperazines; Protein Kinase C; Staurosporine; Substrate Specificity | 1996 |
Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibodies, Anti-Idiotypic; Antigens, CD; B-Lymphocytes; B7-2 Antigen; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Immunoglobulins; Ionomycin; Isoquinolines; Lymphoma, B-Cell; Membrane Glycoproteins; Mice; Molecular Sequence Data; Phosphorylation; Piperazines; Protein Kinase C; Rats; Receptors, Antigen, B-Cell; Signal Transduction; Staurosporine; Sulfonamides | 1996 |
Reversible phosphorylation as a controlling factor for sustaining calcium oscillations in HeLa cells: Involvement of calmodulin-dependent kinase II and a calyculin A-inhibitable phosphatase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Binding Sites; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Enzyme Inhibitors; Ethers, Cyclic; HeLa Cells; Histamine; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoquinolines; Maleimides; Marine Toxins; Molecular Sequence Data; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; Ryanodine; Spectrometry, Fluorescence; Staurosporine; Sulfonamides | 1996 |
Calcium-and phorbol ester-dependent calponin phosphorylation in homogenates of swine carotid artery.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Calponins; Carotid Arteries; Electrophoresis; Enzyme Inhibitors; Microfilament Proteins; Muscle Proteins; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Staurosporine; Swine | 1996 |
Feedback regulation of Na channels in rat CCT. IV. Mediation by activation of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Feedback; Female; Kidney Tubules, Collecting; Male; Ouabain; Patch-Clamp Techniques; Phorbols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Staurosporine; Tetradecanoylphorbol Acetate; Up-Regulation | 1996 |
Relaxin stimulates atrial natriuretic peptide secretion in perfused rat heart.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart; Heart Rate; Isoquinolines; Male; Perfusion; Protein Kinase C; Rats; Rats, Sprague-Dawley; Relaxin; Staurosporine; Stimulation, Chemical; Sulfonamides | 1996 |
Ca(2+)-induced rebound potentiation of gamma-aminobutyric acid-mediated currents requires activation of Ca2+/calmodulin-dependent kinase II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cerebellum; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Kinetics; Marine Toxins; Membrane Potentials; Nerve Fibers; Oxazoles; Purkinje Cells; Rats; Receptors, GABA-A; Signal Transduction; Staurosporine | 1996 |
Calmodulin-dependent protein kinases mediate calcium-induced slow motility of mammalian outer hair cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Azepines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hair Cells, Auditory, Outer; Ionomycin; Ionophores; Isoquinolines; Myosin-Light-Chain Kinase; Naphthalenes; Phosphorylation; Staurosporine; Sulfonamides | 1997 |
Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Apoptosis; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Enzyme Inhibitors; Flavanones; Flavonoids; Genistein; Hippocampus; Indole Alkaloids; Male; Microscopy, Electron; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neurons; Okadaic Acid; Organ Culture Techniques; Phosphoric Monoester Hydrolases; Propidium; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Staurosporine; Sulfonamides | 1998 |
Prostaglandin E2 increases proenkephalin mRNA level in rat astrocyte-enriched culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Dinoprostone; Enkephalins; Enzyme Inhibitors; Flavonoids; Imidazoles; Isoquinolines; Kinetics; Nimodipine; omega-Conotoxin GVIA; Peptides; Phosphorylation; Protein Precursors; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Sulfonamides; Transcription Factor AP-1; Transcription, Genetic | 1998 |
Involvement of calmodulin and protein kinase C in the regulation of K+ transport by carbachol across the rat distal colon.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbachol; Cholinergic Agonists; Colon; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Ion Transport; Potassium; Protein Kinase C; Rats; Rats, Wistar; Rubidium Radioisotopes; Staurosporine | 1999 |
Polycations induce calcium signaling in glomerular podocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Animals; Benzoquinones; Calcium Signaling; Cells, Cultured; DEAE-Dextran; Heparin; Kidney Glomerulus; Lactams, Macrocyclic; Marine Toxins; Mice; Muramidase; Oxazoles; Protamines; Quinones; Rifabutin; Staurosporine; Thapsigargin | 1999 |
Short- and long-term memory are differentially affected by metabolic inhibitors given into hippocampus and entorhinal cortex.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Animals; Avoidance Learning; Carbazoles; Entorhinal Cortex; Enzyme Inhibitors; Flavonoids; Guanylate Cyclase; Hippocampus; Indoles; Inhibition, Psychological; Male; Memory; Memory, Short-Term; Phenols; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Sodium Chloride; Staurosporine | 2000 |
A novel protein kinase from Brassica juncea stimulated by a protozoan calcium binding protein. Purification and partial characterization.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brassica; Calcium; Calcium Signaling; Calcium-Binding Proteins; Calmodulin; Chelating Agents; Egtazic Acid; Entamoeba histolytica; Histones; Immunoglobulin G; Intercellular Signaling Peptides and Proteins; Peptides; Phosphorylation; Phosphoserine; Plant Proteins; Protein Kinases; Protein Processing, Post-Translational; Protozoan Proteins; Recombinant Fusion Proteins; Staurosporine; Sulfonamides | 2000 |
Effects of extracellular calcium and potassium on the sodium pump of rat adrenal glomerulosa cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldosterone; Animals; Calcimycin; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Enzyme Inhibitors; Extracellular Space; Female; Imidazoles; Intracellular Fluid; Ionophores; Isradipine; Potassium; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Sodium-Potassium-Exchanging ATPase; Staurosporine; Zona Glomerulosa | 2001 |
Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Indoles; Isoquinolines; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Phosphorylation; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Staurosporine; Sulfonamides; Synaptosomes; Tetradecanoylphorbol Acetate | 2001 |
The CEACAM1-L Ser503 residue is crucial for inhibition of colon cancer cell tumorigenicity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoembryonic Antigen; Carcinogenicity Tests; Carcinoma; Cell Adhesion Molecules; Colonic Neoplasms; Cyclic AMP; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Naphthalenes; Point Mutation; Protein Kinase C; Serine; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured | 2001 |
Mechanisms intrinsic to 5-HT2B receptor-induced potentiation of NMDA receptor responses in frog motoneurones.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Ergolines; Excitatory Amino Acid Antagonists; Gallopamil; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Indoles; Magnesium; Memantine; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nifedipine; Protein Kinase C; Pyridines; Rana pipiens; Receptor, Serotonin, 5-HT2B; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Staurosporine; Sulfonamides; Tetrodotoxin | 2004 |
Activity-dependent and -independent nuclear fluxes of HDAC4 mediated by different kinases in adult skeletal muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Active Transport, Cell Nucleus; Adenoviridae; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cells, Cultured; Cytoplasm; DNA-Binding Proteins; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Fluorescence Recovery After Photobleaching; Gene Expression Regulation, Enzymologic; Green Fluorescent Proteins; Histone Deacetylases; Kinetics; MEF2 Transcription Factors; Mice; Mice, Inbred Strains; Microscopy, Confocal; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Myogenic Regulatory Factors; Recombinant Fusion Proteins; Staurosporine; Time Factors; Transcription Factors | 2005 |
Vacuolar ATPase regulates surfactant secretion in rat alveolar type II cells by modulating lamellar body calcium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Hydrogen-Ion Concentration; Macrolides; Male; Membrane Microdomains; Organelles; Protein Kinase C; Protein Subunits; Proteomics; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; RNA Interference; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staurosporine; Vacuolar Proton-Translocating ATPases | 2010 |