staurosporine has been researched along with indomethacin in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (8.70) | 18.7374 |
| 1990's | 33 (71.74) | 18.2507 |
| 2000's | 6 (13.04) | 29.6817 |
| 2010's | 3 (6.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Dolphin, AC; McGuirk, SM | 1 |
| Ishihara, M; Jiang, H; Kato, R; Nishikawa, K; Wang, JC; Yamamoto, S | 1 |
| Hassinen, IE; Ruskoaho, H; Uusimaa, PA; Vuolteenaho, O | 1 |
| Frangos, JA; Hsieh, HJ; Li, NQ | 1 |
| Jiang, H; Kato, R; Yamamoto, S | 1 |
| Calixto, JB; Guimarães, CL; Rae, GA | 1 |
| Beraud, M; Cambon, C; Didier, A; Forgue, MF; Pinelli, E; Pipy, B; Souqual, MC; Vandaele, J | 1 |
| Boeckh, C; Otten, U; Pfeilschifter, J; Radeke, H; Steiner, P | 1 |
| Chuang, ST; Grunstein, MM; Pawlowski, NA; Schramm, CM | 1 |
| Burgoyne, RD; Morgan, A | 1 |
| Ando, Y; Breyer, MD; Jacobson, HR | 3 |
| Breyer, JA; Breyer, MD; Jacobson, HR | 1 |
| Iitaka, M; Ishii, J; Kitahama, S | 1 |
| Manzini, S; Palma, C; Urbani, F | 1 |
| Chen, F; Demers, LM; Gaydos, LJ; Kuhn, DC; Sun, SC | 1 |
| Murai, A; Nakahata, N; Nakamura, H; Ohizumi, Y; Rho, MC | 2 |
| Canalis, E; Jeffrey, JJ; Ramsby, ML; Varghese, S | 1 |
| Bennett, SA; Birnboim, HC | 2 |
| Marunouchi, T; Ohno, K; Sawada, M; Suzumura, A | 1 |
| Basudev, H; Howell, SL; Jones, PM; Persaud, SJ | 1 |
| Davis, BB; Thomas, DJ; Zenser, TV | 1 |
| Borzecki, JS; McKay, AJ; Peterson, LN | 1 |
| Fredholm, BB; Lerner, UH; Ljunggren, O; Ljunghall, S; Nordstedt, C | 1 |
| Chang, B; Chang, WC; Jen, CJ; Lin, MT; Shi, GY; Tasi, CF; Wang, SJ; Wing, LY; Wu, HL | 1 |
| Armour, CL; Black, JL; McKay, KO | 1 |
| Baum, C; Hazel, BA; Kalf, GF | 1 |
| Bunton, DC; Martin, D; Nally, JE; Thomson, NC | 1 |
| Kudo, LH; Rouch, AJ | 1 |
| Kruse, ML; Schmidt, WE; Schmidt-Choudhury, A; Schmidtmayer, J; Seebeck, J | 1 |
| Akashi, K; Asayama, J; Kawahara, A; Keira, N; Kobara, M; Matoba, S; Nakagawa, M; Tatsumi, T | 1 |
| Fujimoto, Y; Hirata, M; Inoue, H; Iwao, T; Kajiyama, G; Kariya, K; Kawasaki, Y; Matsubara, K; Morinaka, K; Sasaki, T; Tsuchida, A; Yamamoto, S | 1 |
| Oriji, GK | 1 |
| Diener, M; Heinke, B; Ribeiro, R | 1 |
| Gupte, SA; Ochi, R; Okada, T; Tateyama, M | 1 |
| Al-Azzeh, E; Azarschab, P; Gött, P; Kornberger, W | 1 |
| Kaca, W; Saluk-Juszczak, J; Wachowicz, B; Zielinski, T | 1 |
| Cocker, HA; Kelland, LR; Pinkerton, CR; Pritchard-Jones, K; Tiffin, N | 1 |
| Berg, T | 1 |
| Kim, CH; Kim, HM; Park, SY; Park, WH | 1 |
46 other study(ies) available for staurosporine and indomethacin
| Article | Year |
|---|---|
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
G-protein mediation in nociceptive signal transduction: an investigation into the excitatory action of bradykinin in a subpopulation of cultured rat sensory neurons.
Topics: Alkaloids; Animals; Animals, Newborn; Bradykinin; Cells, Cultured; Evoked Potentials; Ganglia, Spinal; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indomethacin; Kinetics; Masoprocol; Neurons, Afferent; Pain; Protein Kinase C; Rats; Rats, Wistar; Ryanodine; Signal Transduction; Staurosporine | 1992 |
Protein kinase C-dependent and -independent actions of a potent protein kinase C inhibitor, staurosporine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cells, Cultured; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Epidermal Cells; Epidermis; Indomethacin; Isoquinolines; Mice; Ornithine Decarboxylase; Phosphorylation; Piperazines; Protein Kinase C; Proteins; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Endothelin-induced atrial natriuretic peptide release from cultured neonatal cardiac myocytes: the role of extracellular calcium and protein kinase-C.
Topics: Alkaloids; Analysis of Variance; Animals; Animals, Newborn; Atrial Natriuretic Factor; Calcium; Cells, Cultured; Diltiazem; Endothelins; Heart; Indomethacin; Kinetics; L-Lactate Dehydrogenase; Myocardium; Perfusion; Protein Kinase C; Radioimmunoassay; Rats; Staurosporine | 1992 |
Shear-induced platelet-derived growth factor gene expression in human endothelial cells is mediated by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Egtazic Acid; Endothelium, Vascular; Gene Expression Regulation; Guanosine Diphosphate; Humans; Ibuprofen; Indomethacin; Isoquinolines; Neomycin; Piperazines; Platelet-Derived Growth Factor; Protein Kinase C; RNA, Messenger; Signal Transduction; Staurosporine; Stress, Mechanical; Sulfonamides; Transcriptional Activation | 1992 |
Staurosporine, a potent protein kinase C inhibitor, augments phorbol ester-caused ornithine decarboxylase induction in mouse epidermis.
Topics: Administration, Topical; Alkaloids; Animals; Dinoprostone; Drug Synergism; Enzyme Induction; Epidermis; Female; Indomethacin; Mice; Ornithine Decarboxylase; Protein Kinase C; Skin; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Potent constrictor actions of endothelin-1, endothelin-2, and endothelin-3 in rat isolated portal vein.
Topics: Alkaloids; Animals; Benzopyrans; Calcium; Cromakalim; Endothelins; Glyburide; Indomethacin; Male; Mesenteric Veins; Nicardipine; Phorbols; Portal Vein; Protein Kinase C; Pyrroles; Rats; Rats, Inbred Strains; Staurosporine; Vasoconstriction; Vasodilator Agents | 1992 |
Possible implication of arachidonic acid metabolism in the decrease of chemiluminescence production after exposure of murine peritoneal macrophages to diethylnitrosamine and tumour promoter, 12-O-tetradecanoylphorbol-13-acetate.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Cell Survival; Culture Media; Cyclooxygenase Inhibitors; Diethylnitrosamine; Dose-Response Relationship, Drug; Extracellular Space; Female; Indomethacin; Intracellular Fluid; Isoquinolines; Kinetics; Leukotrienes; Luminescent Measurements; Macrophage Activation; Macrophages; Mice; Oxygen; Peritoneal Cavity; Phospholipids; Piperazines; Prostaglandins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tritium | 1991 |
Interleukin-1 beta and tumor necrosis factor-alpha synergistically stimulate nerve growth factor synthesis in rat mesangial cells.
Topics: Alkaloids; Analysis of Variance; Animals; Cells, Cultured; Clone Cells; Diclofenac; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glomerular Mesangium; Indomethacin; Interleukin-1; Kinetics; Male; Masoprocol; Nerve Growth Factors; Protein Kinase C; Rats; Rats, Inbred Strains; Recombinant Proteins; RNA, Messenger; Staurosporine; Tumor Necrosis Factor-alpha | 1991 |
Role of endothelin 1 in regulating rabbit airway contractility.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Dinoprostone; Endothelins; Epithelium; Epoprostenol; In Vitro Techniques; Indomethacin; Isometric Contraction; Isoquinolines; Kinetics; Muscle, Smooth; Piperazines; Protein Kinase Inhibitors; Rabbits; Reference Values; Staurosporine; Sulfonamides; Trachea | 1991 |
Relationship between arachidonic acid release and Ca2(+)-dependent exocytosis in digitonin-permeabilized bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cattle; Cell Membrane Permeability; Chromaffin Granules; Cyclohexanones; Digitonin; Ethylmaleimide; Exocytosis; Indomethacin; Phospholipases A; Phospholipases A2; Protein Kinase C; Quinacrine; Staurosporine | 1990 |
Dose-dependent heterogenous actions of vasopressin in rabbit cortical collecting ducts.
Topics: Alkaloids; Animals; Arginine Vasopressin; Calcium; Dose-Response Relationship, Drug; Female; Homeostasis; Indomethacin; Kidney Tubules; Kidney Tubules, Collecting; Protein Kinase C; Rabbits; Staurosporine; Water-Electrolyte Balance | 1989 |
Phosphatidates inhibit vasopressin-induced water transport via protein kinase C activation.
Topics: Alkaloids; Animals; Arginine Vasopressin; Body Water; Calcium; Enzyme Activation; Female; In Vitro Techniques; Indomethacin; Kidney Cortex; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Phosphatidic Acids; Protein Kinase C; Rabbits; Signal Transduction; Staurosporine | 1989 |
Epidermal growth factor inhibits the hydroosmotic effect of vasopressin in the isolated perfused rabbit cortical collecting tubule.
Topics: Alkaloids; Animals; Arginine Vasopressin; Cyclic AMP; Electric Conductivity; Epidermal Growth Factor; Epithelium; Female; Indomethacin; Kidney Cortex; Kidney Tubules; Kidney Tubules, Collecting; Osmolar Concentration; Perfusion; Rabbits; Staurosporine; Thionucleotides; Water-Electrolyte Balance | 1988 |
Phorbol ester and A23187 have additive but mechanistically separate effects on vasopressin action in rabbit collecting tubule.
Topics: Alkaloids; Animals; Arginine Vasopressin; Calcimycin; Calcium; Enzyme Activation; Female; Indomethacin; Kidney Tubules; Kidney Tubules, Collecting; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Staurosporine; Temperature; Tetradecanoylphorbol Acetate | 1988 |
Involvement of protein kinase A and C in the production of interleukin-1 alpha-induced prostaglandin E2 from mouse osteoblast-like cell line, MC3T3-E1.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dinoprostone; Humans; Indoles; Indomethacin; Interleukin-1; Isoquinolines; Kinetics; Mice; Osteoblasts; Piperazines; Protein Kinase C; Pyrroles; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Interleukin-6 production by U373 MG, a human astrocytoma cell line: different pathways involved in substance P and lipopolysaccharide activation.
Topics: Alkaloids; Astrocytoma; Bucladesine; Calcimycin; Cholera Toxin; Humans; Indomethacin; Interleukin-6; Lipopolysaccharides; Receptors, Neurokinin-1; Staurosporine; Substance P; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages.
Topics: Acetylcysteine; Alkaloids; Animals; Arginine; Base Sequence; Cell Line; Cell Nucleus; Enzyme Inhibitors; Indomethacin; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Molecular Sequence Data; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotide Probes; omega-N-Methylarginine; Protein Kinase C; Silicon Dioxide; Staurosporine; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine | 1995 |
Activation of rabbit platelets by Ca2+ influx and thromboxane A2 release in an external Ca(2+)-dependent manner by zooxanthellatoxin-A, a novel polyol.
Topics: Alkaloids; Animals; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Chlorpheniramine; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Unsaturated; Genistein; Histamine H1 Antagonists; Hydrazines; Imidazoles; Indomethacin; Isoflavones; Male; Marine Toxins; Methysergide; Platelet Aggregation Inhibitors; Polyenes; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; Serotonin Antagonists; Staurosporine; Tetrodotoxin; Thromboxane A2; Thromboxane B2 | 1995 |
Basic fibroblast growth factor stimulates expression of interstitial collagenase and inhibitors of metalloproteinases in rat bone cells.
Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Blotting, Northern; Cells, Cultured; Collagenases; Cycloheximide; Dose-Response Relationship, Drug; Fetus; Fibroblast Growth Factor 2; Gene Expression; Glycoproteins; Indomethacin; Kinetics; Matrix Metalloproteinase 1; Osteoblasts; Protein Kinase C; Pyrimidine Nucleosides; Rats; Recombinant Proteins; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tissue Inhibitor of Metalloproteinases; Transcription, Genetic | 1995 |
Platelet activating factor induces transformation of human fibroblasts.
Topics: Alkaloids; Analysis of Variance; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Genistein; Growth Inhibitors; Humans; Indomethacin; Infant, Newborn; Isoflavones; Phospholipid Ethers; Platelet Activating Factor; Protein Kinase C; Skin; Staurosporine | 1995 |
Regulation of astrocyte proliferation by prostaglandin E2 and the alpha subtype of protein kinase C.
Topics: Alkaloids; Animals; Astrocytes; Cell Division; Cells, Cultured; Dinoprostone; Enzyme Activation; Indomethacin; Lipopolysaccharides; Mice; Mice, Inbred ICR; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Arachidonic acid-induced insulin secretion from rat islets of Langerhans is not mediated by protein phosphorylation.
Topics: Alkaloids; Animals; Arachidonic Acid; Cyclic AMP; Fatty Acids, Unsaturated; Indomethacin; Insulin; Insulin Secretion; Islets of Langerhans; Masoprocol; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Rats; Staurosporine | 1993 |
Cyclic adenosine monophosphate response in primary and subcultured bladder epithelial cells: inhibition by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Alkaloids; Animals; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Dogs; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Epithelium; Indomethacin; Models, Biological; Protein Kinase C; Second Messenger Systems; Signal Transduction; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Urinary Bladder | 1993 |
Endogenous prostaglandin E2 mediates inhibition of rat thick ascending limb Cl reabsorption in chronic hypercalcemia.
Topics: Alkaloids; Animals; Biological Transport, Active; Chlorides; Chronic Disease; Colforsin; Cyclic AMP; Dihydrotachysterol; Dinoprostone; Furosemide; Hypercalcemia; In Vitro Techniques; Indomethacin; Kidney Medulla; Kidney Tubules, Collecting; Male; Perfusion; Rats; Rats, Sprague-Dawley; Staurosporine | 1993 |
Role of protein kinase C in bradykinin-induced prostaglandin formation in osteoblasts.
Topics: Alkaloids; Animals; Bradykinin; Calcimycin; Cell Membrane; Cells, Cultured; Dinoprostone; Enzyme Activation; Hydrocortisone; Indomethacin; Mice; Osteoblasts; Phorbol 12,13-Dibutyrate; Prostaglandins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Regulation of plasminogen activator inhibitor activity by plasmin in endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aspirin; Cells, Cultured; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Fibrinolysin; Fibrinolysis; Gene Expression Regulation; GTP-Binding Proteins; Humans; Indomethacin; Isoquinolines; Lipoxygenase Inhibitors; Masoprocol; Pertussis Toxin; Phospholipases A; Phospholipases A2; Piperazines; Plasminogen Activator Inhibitor 1; Protein Kinase C; Quinacrine; Staurosporine; Tissue Plasminogen Activator; Umbilical Veins; Virulence Factors, Bordetella | 1996 |
Endothelin receptors and activity differ in human, dog, and rabbit lung.
Topics: Animals; Bronchi; Calcium; Calcium Channel Blockers; Dogs; Endothelin Receptor Antagonists; Endothelins; Extracellular Space; Humans; Indomethacin; Peptide Fragments; Peptides, Cyclic; Rabbits; Receptors, Endothelin; Staurosporine; Verapamil | 1996 |
Hydroquinone, a bioreactive metabolite of benzene, inhibits apoptosis in myeloblasts.
Topics: Animals; Apoptosis; Cell Division; Cell Survival; Cysteine Endopeptidases; DNA Fragmentation; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Hydroquinones; Indomethacin; Interleukin-3; Mice; Mutagens; Radiation-Sensitizing Agents; Staurosporine | 1996 |
The role of cyclooxygenase and 5-lipoxygenase metabolites in potentiated endothelin-1-evoked contractions in bovine bronchi.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bronchial Hyperreactivity; Cattle; Cyclooxygenase Inhibitors; Drug Synergism; Endothelin-1; Enzyme Inhibitors; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Muscle Contraction; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Staurosporine | 1996 |
Involvement of phospholipase C-gamma2 in activation of mitogen-activated protein kinase and phospholipase A2 by zooxanthellatoxin-A in rabbit platelets.
Topics: Animals; Arachidonic Acid; Blood Platelets; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Genistein; Indomethacin; Isoflavones; Male; Naphthalenes; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Phosphorylation; Polyenes; Rabbits; Staurosporine; Type C Phospholipases; Tyrosine | 1997 |
Indomethacin and staurosporine reverse alpha 2 inhibition of water transport in rat IMCD.
Topics: Animals; Arginine Vasopressin; Body Water; Imidazoles; Indomethacin; Kidney Medulla; Kidney Tubules, Collecting; Medetomidine; Prostaglandins; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Staurosporine | 1997 |
Receptor-mediated and protein kinase-dependent growth enhancement of primary human fibroblasts by platelet activating factor.
Topics: Animals; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Fibroblasts; Genistein; Humans; Indomethacin; Infant, Newborn; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Protein Kinase C; Protein Kinases; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sepharose; Skin; Staurosporine; Transcription, Genetic; Up-Regulation | 1997 |
Pituitary adenylate cyclase activating polypeptide induces multiple signaling pathways in rat peritoneal mast cells.
Topics: Adenylate Cyclase Toxin; Animals; Bridged-Ring Compounds; Estrenes; Indomethacin; Masoprocol; Mast Cells; Neuropeptides; Norbornanes; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Pertussis Toxin; Phospholipid Ethers; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyrrolidinones; Rats; Signal Transduction; Staurosporine; Thiocarbamates; Thiones; Virulence Factors, Bordetella | 1998 |
Cardioprotective effect of angiotensin-converting enzyme inhibition against hypoxia/reoxygenation injury in cultured rat cardiac myocytes.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Cell Hypoxia; Cells, Cultured; Cilazapril; Creatine Kinase; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Guanidines; Indomethacin; Methylene Blue; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Rats; Rats, Wistar; Staurosporine; Tetrazoles | 1999 |
Cholecystokinin regulates the invasiveness of human pancreatic cancer cell lines via protein kinase C pathway.
Topics: Blotting, Western; Cholecystokinin; Collagenases; Cyclooxygenase Inhibitors; Dinoprostone; Dopamine Agents; Enzyme Induction; Enzyme Inhibitors; Humans; Immunoenzyme Techniques; Indomethacin; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Pancreatic Neoplasms; Protein Kinase C; Signal Transduction; Sincalide; Staurosporine; Tumor Cells, Cultured | 1999 |
Endothelin-induced prostacyclin production in rat aortic endothelial cells is mediated by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Arachidonic Acid; Cells, Cultured; Eicosanoids; Endothelins; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Epoprostenol; Indomethacin; Male; Protein Kinase C; Rats; Staurosporine | 1999 |
Involvement of calmodulin and protein kinase C in the regulation of K+ transport by carbachol across the rat distal colon.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbachol; Cholinergic Agonists; Colon; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Ion Transport; Potassium; Protein Kinase C; Rats; Rats, Wistar; Rubidium Radioisotopes; Staurosporine | 1999 |
Activation of TxA2/PGH2 receptors and protein kinase C contribute to coronary dysfunction in superoxide treated rat hearts.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium Channel Blockers; Cardiovascular Agents; Coronary Disease; Dinoprost; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Male; Methacrylates; Naphthalenes; Perfusion; Prostaglandins; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Staurosporine; Superoxides; Thromboxane A2; Thromboxane-A Synthase; Vasoconstrictor Agents | 2000 |
Aspirin promotes TFF2 gene activation in human gastric cancer cell lines.
Topics: Arachidonic Acid; Aspirin; Gastrointestinal Neoplasms; Genes, Reporter; Growth Substances; Humans; Indomethacin; Models, Biological; Mucins; Muscle Proteins; Neuropeptides; Peptides; Protein Kinase C; Response Elements; RNA, Messenger; Sequence Deletion; Signal Transduction; Staurosporine; Transcriptional Activation; Transfection; Trefoil Factor-2; Trefoil Factor-3; Tumor Cells, Cultured | 2001 |
The generation of superoxide anion in blood platelets in response to different forms of Proteus mirabilis lipopolysaccharide: effects of staurosporin, wortmannin, and indomethacin.
Topics: Androstadienes; Animals; Blood Platelets; Cyclooxygenase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Indomethacin; Lipopolysaccharides; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Proteus mirabilis; Signal Transduction; Staurosporine; Superoxides; Swine; Wortmannin | 2001 |
In vitro prevention of the emergence of multidrug resistance in a pediatric rhabdomyosarcoma cell line.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Cisplatin; Cyclosporins; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Inhibitory Concentration 50; Piperidines; Pyridines; Quinolines; Razoxane; Rhabdomyosarcoma; RNA, Neoplasm; Staurosporine; Time Factors; Tumor Cells, Cultured; Vincristine | 2001 |
The vascular response to the K+ channel inhibitor 4-aminopyridine in hypertensive rats.
Topics: 4-Aminopyridine; Adrenalectomy; Adrenergic Antagonists; Amifampridine; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Indomethacin; Losartan; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phentolamine; Potassium Channel Blockers; Prazosin; Protein Kinase C; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Staurosporine; Sulfonamides; Vascular Resistance; Vasoconstriction | 2003 |
Effect of a Korean traditional formulation, Hwaotang, on superoxide generation in human neutrophils, platelet aggregation in human blood, and nitric oxide, prostaglandin E2 production and paw oedema induced by carrageenan in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Carrageenan; Cell Degranulation; Cyclooxygenase 1; Cyclooxygenase 2; Cytochalasin B; Dinoprostone; Edema; Female; Gastric Mucosa; Gene Expression; Genistein; Hindlimb; Humans; Indomethacin; Isoenzymes; Korea; Leukotriene B4; Lipopolysaccharides; Macrophages, Peritoneal; Medicine, East Asian Traditional; Membrane Proteins; Mice; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pancreatic Elastase; Phosphoproteins; Phosphorylation; Phosphotyrosine; Plant Extracts; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Staurosporine; Stomach; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 2004 |