Page last updated: 2024-08-23

staurosporine and indirubin-3'-monoxime

staurosporine has been researched along with indirubin-3'-monoxime in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (70.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhattacharjee, AK; Ellis, W; Gerena, L; Geyer, JA; Kathcart, AK; Kyle, DE; Li, Z; Lopez-Sanchez, M; Nichols, DA; Prigge, ST; Terrell, J; Waters, NC; Woodard, CL1
Bertrand, JA; Cristiani, C; Flocco, M; Kalisz, HM; Knapp, S; Thieffine, S; Valsasina, B; Vulpetti, A1
Bhattacharjee, AK; Geyer, JA; Kathcart, AK; Li, Z; Mott, BT; Nichols, DA; Prigge, ST; Waters, NC; Woodard, CL1
Flajolet, M; Greengard, P; Meijer, L1
Goekjian, P; Jochum, A; Jung, M; Kunick, C; Marshall, B; Meier, R; Saunders, L; Sippl, W; Trapp, J; Verdin, E1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Jagarlapudi, SA; Sinha, BN; Tajne, S; Vadivelan, S1
Anderson, E; Boardman, PE; Bryk, R; Chao, P; Cole, JL; Conn, GL; Duffy, NP; Griffin, JH; Nathan, C; Raimundo, BC; Wu, K1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1
Cheng, X; Christ, J; Eisenbrand, G; Merz, KH; Muehlbeyer, S; Thommet, A; Vatter, S; Wölfl, S; Zeller, J1

Reviews

1 review(s) available for staurosporine and indirubin-3'-monoxime

ArticleYear
Pharmacological inhibitors of glycogen synthase kinase 3.
    Trends in pharmacological sciences, 2004, Volume: 25, Issue:9

    Topics: Animals; Cell Differentiation; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Neoplasms; Nervous System Diseases; Parasitic Diseases; Signal Transduction; Stem Cells; Structure-Activity Relationship

2004

Other Studies

9 other study(ies) available for staurosporine and indirubin-3'-monoxime

ArticleYear
Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.
    Journal of medicinal chemistry, 2003, Aug-28, Volume: 46, Issue:18

    Topics: Amino Acid Sequence; Animals; Antimalarials; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Molecular Sequence Data; Plasmodium falciparum; Structure-Activity Relationship

2003
Structural characterization of the GSK-3beta active site using selective and non-selective ATP-mimetic inhibitors.
    Journal of molecular biology, 2003, Oct-17, Volume: 333, Issue:2

    Topics: Adenosine Triphosphate; Antibiotics, Antineoplastic; Benzazepines; Binding Sites; Binding, Competitive; CDC2 Protein Kinase; Crystallography, X-Ray; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Growth Inhibitors; Humans; Indoles; Maleimides; Molecular Mimicry; Phosphorylation; Protein Conformation; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Staurosporine; Structure-Activity Relationship

2003
A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors.
    Journal of medicinal chemistry, 2004, Oct-21, Volume: 47, Issue:22

    Topics: Adenosine Triphosphate; Animals; Antimalarials; Binding Sites; Cyclin-Dependent Kinases; Databases, Factual; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Plasmodium falciparum; Protein Kinases; Protozoan Proteins; Quantitative Structure-Activity Relationship

2004
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition.
    Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25

    Topics: Acetylation; Adenosine; Binding Sites; Cell Line, Tumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Mimicry; Protein Kinase Inhibitors; Sirtuins; Structure-Activity Relationship; Tubulin

2006
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Fragment and knowledge-based design of selective GSK-3beta inhibitors using virtual screening models.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:6

    Topics: Algorithms; Computer Simulation; Databases, Factual; Drug Design; Drug Evaluation, Preclinical; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Models, Chemical; Models, Molecular; Molecular Structure; Oxazines; Protein Kinase Inhibitors; Quinazolines; Reproducibility of Results; Stereoisomerism; Structure-Activity Relationship

2009
Identification of new inhibitors of protein kinase R guided by statistical modeling.
    Bioorganic & medicinal chemistry letters, 2011, Jul-01, Volume: 21, Issue:13

    Topics: Animals; Computer Simulation; Dose-Response Relationship, Drug; eIF-2 Kinase; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Macrophages; Mice; Models, Statistical; Molecular Structure; Small Molecule Libraries

2011
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013
Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule.
    Journal of medicinal chemistry, 2017, 06-22, Volume: 60, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Drug Screening Assays, Antitumor; Humans; Indoles; Oximes; Protein Kinase Inhibitors; Receptor, IGF Type 1; Signal Transduction; Solubility; Structure-Activity Relationship

2017