staurosporine and h 89

Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Methylamines; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Structure-Activity Relationship

Topics: Adrenal Medulla; Alkaloids; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cattle; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Enzyme Activation; Enzyme Inhibitors; Histamine; Indoles; Inositol Phosphates; Isoquinolines; Norepinephrine; Protein Kinase C; Signal Transduction; Staurosporine; Sulfonamides; Type C Phospholipases

Topics: Alkaloids; Carrier Proteins; Cholera Toxin; Choriocarcinoma; Cocaine; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Female; Humans; Isoquinolines; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Pregnancy; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

Topics: Alkaloids; Animals; Base Sequence; Bucladesine; Cell Line; Cell Line, Transformed; Cell Nucleus; Cyclic AMP-Dependent Protein Kinases; DNA, Viral; Gene Expression Regulation, Viral; Genes, ras; Isoquinolines; Kinetics; Minute Virus of Mice; Molecular Sequence Data; Nucleic Acid Conformation; Plasmids; Promoter Regions, Genetic; Rats; Rats, Inbred F344; Regulatory Sequences, Nucleic Acid; Staurosporine; Sulfonamides; TATA Box; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Viral Nonstructural Proteins

Topics: Alkaloids; Animals; Calmodulin; Cattle; Cell Division; Cell Line; Contact Inhibition; Culture Media; Culture Media, Serum-Free; Cyclic AMP-Dependent Protein Kinases; DNA Replication; Epithelial Cells; Epithelium; Fetal Blood; Gene Expression Regulation; Ionomycin; Isoquinolines; Kidney; Protein Kinase C; Rats; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic

Topics: Alkaloids; Bucladesine; Cell Division; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplasm; Enzyme Activation; Gene Expression; Humans; Indoles; Isoquinolines; Leukemia, Promyelocytic, Acute; Maleimides; Protein Kinase C; Protein Kinases; Receptors, Transferrin; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured

Topics: Alkaloids; Animals; Cell Line; Cell Line, Transformed; Collagen; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Edetic Acid; Fibroblasts; Gene Expression; Genes, jun; Genes, ras; Isoquinolines; Kinetics; Oncogene Protein p65(gag-jun); Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins c-jun; Rats; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alkaloids; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cholera Toxin; Dose-Response Relationship, Drug; Ganglia, Invertebrate; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kynurenic Acid; Membrane Potentials; Neurons; Pertussis Toxin; Piperazines; Potassium Channels; Protein Kinase Inhibitors; Snails; Staurosporine; Sulfonamides; Time Factors; Virulence Factors, Bordetella

Topics: Alkaline Phosphatase; Alkaloids; Animals; Bucladesine; Calcimycin; Cyclic AMP; Cycloheximide; Dinoprostone; Isoquinolines; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Alkaloids; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Electric Conductivity; Ferrets; Heart; Heart Ventricles; Isoquinolines; Myocardium; Peptide Fragments; Piperazines; Rabbits; Staurosporine; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Hydroxybenzoates; Isoquinolines; Mice; Muscles; Piperazines; Receptors, Nicotinic; Staurosporine; Sulfonamides; Time Factors

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adipose Tissue; Alkaloids; Animals; Cell Differentiation; Cells, Cultured; Culture Media, Serum-Free; Glycerolphosphate Dehydrogenase; Isoquinolines; Male; Piperazines; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bucladesine; Cell Death; Cell Hypoxia; Cells, Cultured; Dibutyryl Cyclic GMP; Hippocampus; Isoquinolines; Nerve Tissue Proteins; Nitric Oxide; Phorbol Esters; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sphingosine; Staurosporine; Sulfonamides

Topics: Alkaloids; Bucladesine; Enzyme Activation; Humans; In Vitro Techniques; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipase D; Protein Kinase C; Staurosporine; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminopyrine; Animals; Calcium; Carbachol; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dogs; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Gastric Acid; Inositol 1,4,5-Trisphosphate; Isoquinolines; Parasympathomimetics; Parietal Cells, Gastric; Piperazines; Protein Kinase C; Receptors, Muscarinic; Staurosporine; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibodies, Anti-Idiotypic; Antigens, CD; B-Lymphocytes; B7-2 Antigen; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Immunoglobulins; Ionomycin; Isoquinolines; Lymphoma, B-Cell; Membrane Glycoproteins; Mice; Molecular Sequence Data; Phosphorylation; Piperazines; Protein Kinase C; Rats; Receptors, Antigen, B-Cell; Signal Transduction; Staurosporine; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Drug Synergism; Enzyme Inhibitors; In Vitro Techniques; Isoquinolines; Male; Muscle, Smooth, Vascular; Naphthalenes; Nitroglycerin; Potassium Channels; Protein Kinase C; Purinones; Rats; Rats, Wistar; Staurosporine; Sulfonamides; Vasodilator Agents

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart; Heart Rate; Isoquinolines; Male; Perfusion; Protein Kinase C; Rats; Rats, Sprague-Dawley; Relaxin; Staurosporine; Stimulation, Chemical; Sulfonamides

Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Staurosporine; Sulfonamides; Time Factors; Ureter

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides

Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Antibodies; Base Sequence; Cell Line; Cells, Cultured; Conserved Sequence; DNA Primers; Enzyme Inhibitors; Epithelium; Female; Gene Expression; Genistein; Isoflavones; Isoquinolines; Kinetics; Mammary Glands, Animal; Mice; Molecular Sequence Data; Mucin-1; Naphthalenes; Peptide Fragments; Polymerase Chain Reaction; Pregnancy; Protein Biosynthesis; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Uterus

Topics: Animals; Calcium; Cell Aggregation; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Enzyme Inhibitors; Eosinophils; Female; GTP-Binding Proteins; Guinea Pigs; Indoles; Isoenzymes; Isoquinolines; Leukotriene B4; Pertussis Toxin; Phospholipase C beta; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Staurosporine; Sulfonamides; Type C Phospholipases; Virulence Factors, Bordetella

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibodies, Monoclonal; Cell Adhesion; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Female; Intercellular Adhesion Molecule-1; Isoquinolines; Liver Neoplasms, Experimental; Lymphocyte Function-Associated Antigen-1; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Tumor Cells, Cultured

Topics: Adenoviruses, Human; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endocytosis; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; Humans; Indole Alkaloids; Indoles; Isoflavones; Isoquinolines; Lactoferrin; Low Density Lipoprotein Receptor-Related Protein-1; Maleimides; Melanoma; Naphthalenes; Phenols; Protein Kinase C; Receptors, Immunologic; Signal Transduction; Staurosporine; Sulfonamides; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

Topics: Adenosine Triphosphate; Amides; Animals; Cell Membrane; Cyclic AMP; Dithiothreitol; Enzyme Inhibitors; Isoquinolines; Kinetics; Liver; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxidants; Oxidation-Reduction; Protein Kinase Inhibitors; Rats; Reducing Agents; Staurosporine; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Azepines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hair Cells, Auditory, Outer; Ionomycin; Ionophores; Isoquinolines; Myosin-Light-Chain Kinase; Naphthalenes; Phosphorylation; Staurosporine; Sulfonamides

Topics: Alkaloids; Animals; Benzophenanthridines; Carcinogens; Cell Membrane; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Growth Hormone; Growth Hormone-Releasing Hormone; Isoquinolines; Naphthalenes; Oligopeptides; Phenanthridines; Pituitary Gland; Protein Kinase C; Second Messenger Systems; Sheep; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors

Topics: Alkaloids; Cell Differentiation; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glutathione; Humans; Isoquinolines; Naphthol AS D Esterase; Naphthoquinones; Nitroblue Tetrazolium; Phagocytosis; Protein Kinase C; Staurosporine; Sulfonamides; Tumor Cells, Cultured

Topics: Cell Division; Cell Nucleus; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Isoquinolines; Lung; Maleimides; Naphthalenes; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine; Sulfonamides

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Carcinogens; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; GTP-Binding Protein alpha Subunits, Gi-Go; Hippocampus; Isoquinolines; Kainic Acid; Membrane Potentials; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Second Messenger Systems; Sodium; Staurosporine; Sulfonamides; Tetraethylammonium; Tetrodotoxin; Thionucleotides; Type C Phospholipases; Virulence Factors, Bordetella

Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenal Glands; Animals; Calcium; Cattle; Chromaffin Cells; Cyclic AMP-Dependent Protein Kinases; Cytosol; Electrophysiology; Enzyme Inhibitors; In Vitro Techniques; Isoquinolines; Magnesium; Membrane Potentials; Nucleotides; Patch-Clamp Techniques; Potassium Channels; Protein Kinase Inhibitors; Staurosporine; Sulfonamides

Topics: Adenylyl Cyclase Inhibitors; Animals; Bivalvia; Cell Size; Cosyntropin; Dideoxyadenosine; Enzyme Inhibitors; GTP-Binding Proteins; Hemocytes; Hemolymph; Image Processing, Computer-Assisted; Isoquinolines; Microscopy, Phase-Contrast; Naphthalenes; Protein Kinase Inhibitors; Signal Transduction; Staurosporine; Sulfonamides; Suramin

Topics: 3T3 Cells; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprost; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Iodides; Isoquinolines; Kinetics; Mice; Phosphopeptides; Phosphorylation; Protein Kinase C; Recombinant Proteins; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Dinoprostone; Enkephalins; Enzyme Inhibitors; Flavonoids; Imidazoles; Isoquinolines; Kinetics; Nimodipine; omega-Conotoxin GVIA; Peptides; Phosphorylation; Protein Precursors; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Sulfonamides; Transcription Factor AP-1; Transcription, Genetic

Topics: Benzoquinones; Cell Division; Cell Survival; Cells, Cultured; DNA; Dose-Response Relationship, Drug; G(M3) Ganglioside; Gangliosides; Humans; Interleukin-10; Isoquinolines; Lactams, Macrocyclic; Protein Kinase Inhibitors; Protein Kinases; Quinones; Rifabutin; RNA, Messenger; Signal Transduction; Staurosporine; Sulfonamides; T-Lymphocytes; Time Factors; Transcriptional Activation

Topics: Adenosine Triphosphate; beta-Thromboglobulin; Blood Platelets; Calcium; Cell Membrane Permeability; Cytoplasmic Granules; Egtazic Acid; Enzyme Inhibitors; Flow Cytometry; Genistein; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Isoquinolines; Magnesium; Manganese; Nucleotides; P-Selectin; Protein Kinase Inhibitors; Protons; Staurosporine; Sulfonamides; Type C Phospholipases; Tyrphostins

Topics: Animals; Carrier Proteins; Cell Line; Ciliary Body; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Hydrogen Peroxide; Isoquinolines; Ouabain; Rabbits; Rubidium; Sodium; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Staurosporine; Sulfonamides

Topics: Animals; Carbazoles; Chromones; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Indole Alkaloids; Indoles; Interleukin-6; Isoquinolines; Macrophages, Peritoneal; Male; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Sulfonamides; Time Factors

Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; Enzyme Inhibitors; Flavonoids; Indoles; Isoquinolines; Kinetics; Lysophosphatidylcholines; Myocardium; Nimodipine; Phospholipases A; Protein Kinase C; Rats; Staurosporine; Structure-Activity Relationship; Sulfonamides

Topics: Arrestins; beta-Adrenergic Receptor Kinases; beta-Arrestins; Biological Transport; Cell Compartmentation; Cyclic AMP-Dependent Protein Kinases; Dynamins; Endocytosis; GTP Phosphohydrolases; GTP-Binding Proteins; Isoquinolines; Oligopeptides; Peptide Fragments; Peptides; Phosphorylation; Protein Kinases; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, beta-2; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Receptors, Gastrointestinal Hormone; Recombinant Fusion Proteins; Secretin; Sequence Deletion; Staurosporine; Sulfonamides

Topics: Amidines; Animals; Benzylamines; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Line; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Drug Design; Enzyme Inhibitors; Flavonoids; Imidazoles; Indole Alkaloids; Isoquinolines; Lipopolysaccharides; Mice; Microglia; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Pyridines; Staurosporine; Sulfonamides

Topics: Animals; Carbazoles; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Indoles; Isoquinolines; Lipopolysaccharides; Microglia; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Isoforms; Protein Kinase C; Pyrroles; Rats; Signal Transduction; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Animals; Cell Line; Cell Nucleus; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Isoquinolines; Lipopolysaccharides; Lysine; Macrophages; Macrophages, Alveolar; Male; Mice; Molsidomine; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Phagocytosis; Protein Binding; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Silicon Dioxide; Staurosporine; Sulfonamides; Tyrphostins; Up-Regulation

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Indoles; Isoquinolines; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Phosphorylation; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Staurosporine; Sulfonamides; Synaptosomes; Tetradecanoylphorbol Acetate

Topics: 3T3 Cells; Adipocytes; Animals; Fatty Acid Synthases; Gene Expression Regulation, Enzymologic; Growth Hormone; Indoles; Insulin; Isoquinolines; Janus Kinase 2; Maleimides; Mice; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; RNA, Messenger; Signal Transduction; Staurosporine; Sulfonamides

Topics: Animals; Bufo marinus; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphorylation; Rats; Rats, Long-Evans; Staurosporine; Sulfonamides

Topics: Adenosine Triphosphate; Animals; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indole Alkaloids; Indoles; Isoproterenol; Isoquinolines; Maleimides; Marine Toxins; Microcystins; Okadaic Acid; Oxazoles; Parotid Gland; Peptides, Cyclic; Phenols; Phosphorus Radioisotopes; Phosphorylation; Rats; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Staurosporine; Sulfonamides; Sympathomimetics; Vanadates

Topics: Animals; Basilar Artery; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Male; Maleimides; Muscle Contraction; Muscle, Smooth, Vascular; Organ Culture Techniques; Protein Kinase C; Rats; Rats, Inbred WKY; Receptor, Endothelin A; Receptor, Endothelin B; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Endothelin; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Sulfonamides; Up-Regulation

Topics: Animals; Apoptosis; Caspases; Cell Line; Chromones; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Isoquinolines; Macrophages; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Staurosporine; Sulfonamides

Topics: Androstenedione; Animals; Cells, Cultured; Colforsin; Cordyceps; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Hydroxycholesterols; Isoquinolines; Leydig Cells; Male; Mice; Mice, Inbred C57BL; Mycelium; Progestins; Protein Kinase C; Staurosporine; Sulfonamides; Testosterone; Tetradecanoylphorbol Acetate

Topics: Adenylyl Cyclase Inhibitors; Alkaloids; Aminobenzoates; Animals; Atrial Natriuretic Factor; Benzophenanthridines; Benzothiazoles; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Dose-Response Relationship, Drug; Heart; Heart Atria; Imines; Indoles; Isoquinolines; Ketanserin; Male; Myocytes, Cardiac; Neomycin; para-Aminobenzoates; Perfusion; Phenanthridines; Piperazines; Piperidines; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Staurosporine; Sulfonamides; Thiazoles; Type C Phospholipases

Topics: Blotting, Northern; Blotting, Western; Carrier Proteins; Cell Line, Tumor; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Gene Expression; Humans; Isoquinolines; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Membrane Glycoproteins; Metalloendopeptidases; Osteoblasts; Protein Kinase C; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Signal Transduction; Staurosporine; Sulfonamides; Teriparatide

Topics: Animals; Cell Membrane; Cell Nucleus; COS Cells; Indoles; Intracellular Membranes; Isoquinolines; Maleimides; Microscopy, Fluorescence; Protein Kinase C; Protein Kinases; Protein Structure, Tertiary; Receptor, Fibroblast Growth Factor, Type 4; Receptors, Fibroblast Growth Factor; Sequence Deletion; Staurosporine; Sulfonamides

Topics: Adenosine Triphosphate; Animals; Biological Assay; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorescence; Humans; Isoquinolines; Marine Toxins; Microcystins; Peptide Library; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Staurosporine; Sulfonamides; Vanadates

Topics: Amphibian Proteins; Animals; Arrestins; beta-Arrestin 1; beta-Arrestins; Binding Sites; Cattle; Cell Line; Clathrin-Coated Vesicles; Cyclic AMP-Dependent Protein Kinases; Endocytosis; Humans; Immunohistochemistry; Isoquinolines; Microscopy, Confocal; Mutagenesis, Site-Directed; Peptide Hormones; Peptides; Phosphorylation; Protein Kinase C; Radioligand Assay; Receptors, Corticotropin-Releasing Hormone; Recombinant Proteins; Staurosporine; Sulfonamides

Topics: 8-Bromo Cyclic Adenosine Monophosphate; ADAM Proteins; ADAM17 Protein; Animals; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Dust; Epithelial Cells; Housing, Animal; Humans; Interleukin-6; Isoquinolines; Metalloendopeptidases; Microscopy, Fluorescence; Phosphorylation; Pulmonary Alveoli; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Sulfonamides; Swine; Time Factors; Tumor Necrosis Factor-alpha

Topics: Amiloride; Angiotensin II; Calcium; Cell Line, Tumor; Cell Size; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Hydrogen-Ion Concentration; Isoquinolines; Losartan; Signal Transduction; Sodium-Hydrogen Exchangers; Staurosporine; Sulfonamides

Topics: Animals; Apoptosis; beta Catenin; Bone and Bones; Bone Development; Cell Line, Tumor; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Enzyme Inhibitors; Etoposide; Gene Expression Regulation; Isoquinolines; Lithium Chloride; Luciferases; Mice; Naphthalenes; NIH 3T3 Cells; Osteoblasts; Parathyroid Hormone; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad3 Protein; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Transforming Growth Factor beta

Topics: Actins; Animals; Bumetanide; Carcinoma, Ehrlich Tumor; Cell Membrane; Cell Size; Cell-Free System; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Female; Hypertonic Solutions; Isoquinolines; Marine Toxins; Mice; Myosin Type II; Myosin-Light-Chain Kinase; Oxazoles; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rubidium Radioisotopes; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Staurosporine; Sulfonamides

Topics: Cyclic AMP-Dependent Protein Kinases; Endocytosis; Flavonoids; Fluorescent Antibody Technique; Golgi Apparatus; Horseradish Peroxidase; HT29 Cells; Humans; Isoquinolines; Light; Mitogen-Activated Protein Kinases; Naphthalenes; Staurosporine; Sulfonamides

Topics: Amphotericin B; Animals; Antiprotozoal Agents; Enzyme Inhibitors; Fluorescence; Humans; Indicators and Reagents; Isoquinolines; Leishmania donovani; Leishmania tropica; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Oxazines; Parasitic Sensitivity Tests; Staurosporine; Sulfonamides; Time Factors; Xanthenes

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Bufo arenarum; Chorionic Gonadotropin; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Male; Maleimides; Ouabain; Protein Kinase C; Sertoli Cells; Sodium-Potassium-Exchanging ATPase; Spermatozoa; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Annexin A5; Apoptosis; Bicarbonates; Caspase 3; Cattle; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cytochromes c; Epithelium, Corneal; Estradiol; Isoquinolines; Phosphodiesterase 4 Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Rolipram; Staurosporine; Sulfonamides

Topics: Animals; Benzophenanthridines; Calcium; Calcium Channels, T-Type; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Electrophysiological Phenomena; Isoquinolines; Leydig Cells; Luteinizing Hormone; Male; Mice; Peptides; Protein Kinase C; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: Animals; Cardiac Myosins; Cyclic AMP-Dependent Protein Kinases; Heart Ventricles; Isoquinolines; Male; Myocardial Contraction; Myocardium; Myofibrils; Myosin Light Chains; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rabbits; Staining and Labeling; Staurosporine; Sulfonamides; Time Factors; Tropomyosin; Troponin I; Troponin T

Topics: Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase 8; Caspase 9; Cells, Cultured; Fibroblasts; Isoquinolines; Mice; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Protein Kinase Inhibitors; Staurosporine; Sulfonamides; Thymocytes

Topics: Electrophoresis, Capillary; Fluoresceins; Fluorescence; Isoquinolines; Protein Kinase Inhibitors; Protein Kinases; Spectrometry, Fluorescence; Staurosporine; Sulfonamides

Topics: Apoptosis; Autophagy; Cell Cycle; Ceramides; HCT116 Cells; Humans; Isoquinolines; Membrane Proteins; Microtubule-Associated Proteins; Nuclear Envelope; Nuclear Proteins; Phagosomes; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Signal Transduction; Staurosporine; Sulfonamides