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staurosporine and guanosine triphosphate

staurosporine has been researched along with guanosine triphosphate in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's14 (66.67)18.2507
2000's5 (23.81)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Olianas, MC; Onali, P1
De Lisle, RC; Kitagawa, M; Williams, JA1
Akiba, S; Fujii, T; Sato, T1
Dufau, ML; Fabbri, A; Tinajero, JC; Ulisse, S1
Bizzarri, C; Corda, D; D'Orazio, MC; Di Girolamo, M1
Kakkar, VV; Krishnamurthi, S; Wheeler-Jones, CP1
Honda, Z; Kurokawa, K; Shimizu, T; Waga, I; Watanabe, T1
Janero, DR; Sharif, HM; Thakkar, JK; Yarwood, C1
Beckwith, M; Creekmore, SP; Longo, DL; Mason, AT; McVicar, DW; Ortaldo, JR1
Clancy, J; Emala, CW; Hirshman, CA; Schears, G1
Gomi, Y; Tsunobuchi-Ushijima, H1
Bremerich, DH; Jones, KA; Lorenz, RR; Shumway, R; Warner, DO1
Barber, SA; Clements, JE; Flaherty, MT; Plafker, SM1
Hattori, Y; Kanno, M; Kitabatake, A; Kohya, T; Moriishi, K; Oguma, K; Sasaki, M; Tomita, F1
Flaumenhaft, R; Furie, B; Furie, BC1
Hanson, C; Lyons, R; Muszynski, KW; Ruscetti, SK; Spadaccini, A; Thompson, D1
Bossemeyer, D; Engh, RA1
Kimchi, A; Mukamel, Z1
Gangaraju, S; McBride, H; Neuspiel, M; Rippstein, P; Zunino, R1
Sen, S; Webber, PJ; West, AB1
Potter, LR; Robinson, JW1

Reviews

1 review(s) available for staurosporine and guanosine triphosphate

ArticleYear
The protein kinase activity modulation sites: mechanisms for cellular regulation - targets for therapeutic intervention.
    Advances in enzyme regulation, 2001, Volume: 41

    Topics: Adenosine Triphosphate; Animals; Binding Sites; Catalytic Domain; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Guanosine Triphosphate; Ligands; MAP Kinase Signaling System; Models, Biological; Models, Genetic; Models, Molecular; Protein Binding; Protein Conformation; Protein Isoforms; Protein Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Staurosporine

2001

Other Studies

20 other study(ies) available for staurosporine and guanosine triphosphate

ArticleYear
Naturally occurring opioid receptor agonists stimulate adenylate cyclase activity in rat olfactory bulb.
    Molecular pharmacology, 1991, Volume: 39, Issue:4

    Topics: Adenylyl Cyclases; Alkaloids; Animals; beta-Endorphin; Calcium; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enzyme Activation; Guanosine Triphosphate; Intracellular Fluid; Kinetics; Male; Naloxone; Olfactory Bulb; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Opioid; Staurosporine; Stimulation, Chemical

1991
Amylase release from streptolysin O-permeabilized pancreatic acini.
    The American journal of physiology, 1990, Volume: 259, Issue:2 Pt 1

    Topics: Alkaloids; Amylases; Animals; Bacterial Proteins; Calcium; Cell Membrane Permeability; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Male; Mice; Pancreas; Protein Kinase C; Staurosporine; Streptolysins; Tetradecanoylphorbol Acetate; Thionucleotides

1990
Involvement of a guanine-nucleotide-binding protein-mediated mechanism in the enhancement of arachidonic acid liberation by phorbol 12-myristate 13-acetate and Ca2+ in saponin-permeabilized platelets.
    Biochimica et biophysica acta, 1990, Jun-14, Volume: 1044, Issue:3

    Topics: Alkaloids; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cell Membrane Permeability; Chlorides; Diglycerides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Pertussis Toxin; Protein Kinase C; Rabbits; Saponins; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella

1990
A novel mechanism of action of corticotropin releasing factor in rat Leydig cells.
    The Journal of biological chemistry, 1990, Feb-05, Volume: 265, Issue:4

    Topics: Adenylyl Cyclases; Alkaloids; Animals; Cells, Cultured; Chorionic Gonadotropin; Corticotropin-Releasing Hormone; Cyclic AMP; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Leydig Cells; Male; Protein Kinase C; Rats; Receptors, Corticotropin-Releasing Hormone; Receptors, Neurotransmitter; Sphingosine; Staurosporine; Testosterone; Tetradecanoylphorbol Acetate

1990
Evidence that a guanine nucleotide-binding protein linked to a muscarinic receptor inhibits directly phospholipase C.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:12

    Topics: Alkaloids; Animals; Atropine; Calcimycin; Calcium; Carbachol; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cytosol; GTP-Binding Proteins; Guanosine Triphosphate; Inositol Phosphates; Kinetics; Norepinephrine; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Staurosporine; Type C Phospholipases; Virulence Factors, Bordetella

1990
Effect of phorbol ester treatment on receptor-mediated versus G-protein-activator-mediated responses in platelets. Evidence for a two-site action of phorbol ester at the level of G-protein function.
    The Biochemical journal, 1989, Aug-15, Volume: 262, Issue:1

    Topics: Alkaloids; Blood Platelets; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; In Vitro Techniques; Male; Phosphatidic Acids; Protein Kinase C; Serotonin; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Time Factors; Type C Phospholipases

1989
Prostaglandin F2 alpha stimulates formation of p21ras-GTP complex and mitogen-activated protein kinase in NIH-3T3 cells via Gq-protein-coupled pathway.
    The Journal of biological chemistry, 1995, Apr-14, Volume: 270, Issue:15

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Dinoprost; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Isoquinolines; Mice; Oncogene Protein p21(ras); Piperazines; Protein Kinase Inhibitors; Protein Kinases; Staurosporine

1995
Modulation of mammalian cardiac AMP deaminase by protein kinase C-mediated phosphorylation.
    The Biochemical journal, 1993, Apr-15, Volume: 291 ( Pt 2)

    Topics: Alkaline Phosphatase; Alkaloids; AMP Deaminase; Animals; Calcineurin; Calmodulin-Binding Proteins; Guanosine Triphosphate; Kinetics; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Rabbits; Staurosporine

1993
T cell activation via the disialoganglioside GD3: analysis of signal transduction.
    Journal of leukocyte biology, 1996, Volume: 60, Issue:4

    Topics: Benzoquinones; Calcium; Cells, Cultured; Enzyme Inhibitors; Gangliosides; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Isoenzymes; Lactams, Macrocyclic; Lymphocyte Activation; Phosphatidylinositols; Phospholipase C gamma; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Quinones; Rifabutin; Signal Transduction; Staurosporine; T-Lymphocytes; Type C Phospholipases

1996
Chronic carbachol pretreatment decreases adenylyl cyclase activity in airway smooth muscle.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1

    Topics: Adenylyl Cyclases; Animals; Atropine; Carbachol; Cattle; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Kinetics; Muscle, Smooth; Protein Kinase C; Receptor, Muscarinic M3; Receptors, Muscarinic; Staurosporine; Trachea

1997
Effects of phorbol-12,13-dibutyrate and protein kinase C inhibitors on Mn(2+)-dependent norepinephrine-induced contractions involving increase in Mn2+ sensitivity in Ca(2+)-depleted vas deferens of the guinea pig.
    General pharmacology, 1997, Volume: 29, Issue:4

    Topics: Animals; Calcium; Enzyme Inhibitors; Escin; Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Indoles; Magnesium; Male; Maleimides; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Staurosporine; Vas Deferens

1997
Role of protein kinase C in calcium sensitization during muscarinic stimulation in airway smooth muscle.
    The American journal of physiology, 1997, Volume: 273, Issue:4

    Topics: Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Calcium; Cell Membrane Permeability; Cytosol; Diglycerides; Dogs; Enzyme Inhibitors; Escin; Female; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Naphthalenes; Peptide Fragments; Phenanthridines; Protein Kinase C; Receptors, Muscarinic; Staurosporine; Trachea

1997
A novel kinase activity associated with Nef derived from neurovirulent simian immunodeficiency virus.
    Virology, 1998, Nov-10, Volume: 251, Issue:1

    Topics: Adenosine Triphosphate; Animals; Blotting, Western; Cells, Cultured; Gene Products, nef; Genistein; Guanosine Triphosphate; Humans; Isoelectric Point; Macaca mulatta; Macrophages; Molecular Weight; Mutagenesis, Site-Directed; p21-Activated Kinases; Phosphoamino Acids; Phosphorylation; Precipitin Tests; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteins; Simian Immunodeficiency Virus; Staurosporine; Transfection; U937 Cells

1998
Tyrosine phosphorylation as a convergent pathway of heterotrimeric G protein- and rho protein-mediated Ca2+ sensitization of smooth muscle of rabbit mesenteric artery.
    British journal of pharmacology, 1998, Volume: 125, Issue:8

    Topics: Adenosine Diphosphate; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcium; Carcinogens; Dimerization; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; rho GTP-Binding Proteins; Ribose; Staurosporine; Tyrosine; Tyrphostins; Vasoconstrictor Agents

1998
Alpha-granule secretion from alpha-toxin permeabilized, MgATP-exposed platelets is induced independently by H+ and Ca2+.
    Journal of cellular physiology, 1999, Volume: 179, Issue:1

    Topics: Adenosine Triphosphate; beta-Thromboglobulin; Blood Platelets; Calcium; Cell Membrane Permeability; Cytoplasmic Granules; Egtazic Acid; Enzyme Inhibitors; Flow Cytometry; Genistein; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Isoquinolines; Magnesium; Manganese; Nucleotides; P-Selectin; Protein Kinase Inhibitors; Protons; Staurosporine; Sulfonamides; Type C Phospholipases; Tyrphostins

1999
Growth factor-independent proliferation of erythroid cells infected with Friend spleen focus-forming virus is protein kinase C dependent but does not require Ras-GTP.
    Journal of virology, 2000, Volume: 74, Issue:18

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Blotting, Western; Cell Division; Enzyme Inhibitors; ErbB Receptors; Erythroblasts; Erythropoietin; GRB2 Adaptor Protein; Guanosine Triphosphate; Humans; Indoles; Isoquinolines; Maleimides; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Kinase C; Proteins; Proto-Oncogene Proteins c-raf; ras Proteins; Shc Signaling Adaptor Proteins; Signal Transduction; Spleen Focus-Forming Viruses; Src Homology 2 Domain-Containing, Transforming Protein 1; Staurosporine; Sulfonamides; Transfection; Tumor Cells, Cultured

2000
Death-associated protein 3 localizes to the mitochondria and is involved in the process of mitochondrial fragmentation during cell death.
    The Journal of biological chemistry, 2004, Aug-27, Volume: 279, Issue:35

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Death; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Enzyme Inhibitors; Fibroblasts; Green Fluorescent Proteins; Guanosine Triphosphate; HeLa Cells; Humans; Luminescent Proteins; Mice; Microscopy, Confocal; Mitochondria; Mutation; NIH 3T3 Cells; Precipitin Tests; Protein Biosynthesis; Proteins; Proteome; Rats; Ribosomal Proteins; RNA Interference; RNA-Binding Proteins; Staurosporine; Subcellular Fractions; Transfection

2004
Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization.
    The Journal of biological chemistry, 2005, Jul-01, Volume: 280, Issue:26

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Binding Sites; COS Cells; Cytochromes c; DNA, Complementary; Fluorescent Dyes; Free Radicals; Genes, Dominant; GTP Phosphohydrolases; Guanosine Triphosphate; Humans; Hydrolysis; Membrane Proteins; Microscopy, Electron; Microscopy, Fluorescence; Mitochondria; Mitochondrial Proteins; Mutation; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Time Factors; Transfection

2005
Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization.
    The Journal of biological chemistry, 2009, Dec-25, Volume: 284, Issue:52

    Topics: Amino Acid Substitution; Cell Line; Enzyme Activation; Enzyme Inhibitors; Guanosine Triphosphate; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation, Missense; Parkinson Disease; Protein Multimerization; Protein Serine-Threonine Kinases; Protein Structure, Quaternary; Protein Structure, Tertiary; Staurosporine

2009
ATP potentiates competitive inhibition of guanylyl cyclase A and B by the staurosporine analog, Gö6976: reciprocal regulation of ATP and GTP binding.
    The Journal of biological chemistry, 2011, Sep-30, Volume: 286, Issue:39

    Topics: Adenosine Triphosphate; Binding Sites; Carbazoles; Cell Line; Enzyme Activation; Enzyme Inhibitors; Guanosine Triphosphate; Humans; Protein Binding; Receptors, Atrial Natriuretic Factor; Staurosporine

2011