staurosporine has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 38 (82.61) | 18.2507 |
| 2000's | 8 (17.39) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fleischer, B; Mittrücker, HW | 1 |
| Dolphin, AC; McGuirk, SM | 1 |
| Abraham, RT; Leibson, PJ; Schoon, RA; Ting, AT | 1 |
| Mattera, R; Xing, M | 1 |
| Cockcroft, S; Geny, B | 1 |
| Freissmuth, M; Palmer, S; Pyne, NJ | 1 |
| Buccione, R; De Matteis, MA; Di Tullio, G; Luini, A | 1 |
| Jahr, CE; Nawy, S | 1 |
| De Lisle, RC; Kitagawa, M; Williams, JA | 1 |
| Furuya, W; Grinstein, S | 1 |
| Barreau, P; Basset, M; Cost, H; Geny, B; Le Peuch, C | 1 |
| Bowman, EP; Lambeth, JD; Olson, SC | 1 |
| Akiba, S; Fujii, T; Sato, T | 1 |
| Aiyar, J; Chandy, KG; Grissmer, S | 1 |
| Massry, SG; Ni, Z; Smogorzewski, M | 1 |
| Wang, HL; Wu, T | 1 |
| Akaike, N; Uneyama, C; Uneyama, H | 1 |
| Kitamura, K; Kuriyama, H; Oike, M | 1 |
| Di Marzo, V; Piomelli, D; Schwartz, JC; Sokoloff, P; Vial, D | 1 |
| Akisue, T; Inoue, H; Nakamura, S; Shimooku, K | 1 |
| Huttner, WB; Ohashi, M | 1 |
| Boulay, G; Chrétien, L; Guillemette, G; Richard, DE | 1 |
| Niessen, HW; Verhoeven, AJ | 1 |
| Ali, H; Didsbury, JR; Menard, L; Richardson, RM; Snyderman, R; Tomhave, ED | 1 |
| Breitwieser, GE; Lo, CF | 1 |
| Jones, CT; Khouja, A | 1 |
| Raffaniello, RD; Raufman, JP | 1 |
| Jones, PM; Mann, FM; Persaud, SJ; Wheeler-Jones, CP | 1 |
| Benzing, CF; Kono, T; Robinson, FW; Sumida, Y; Yano, Y | 1 |
| Edwards, SW; Galvani, DW; Lowe, GM; Slupsky, JR | 1 |
| Ali, H; Haribabu, B; Richardson, RM; Snyderman, R | 1 |
| Barritt, GJ; Gregory, RB | 1 |
| García-Sáinz, JA; Medina, LC; Vázquez-Prado, J | 1 |
| Grannass, A; Jakobs, KH; Rümenapp, U; Schmidt, M; Tapp, E; Wahn, F | 1 |
| Jones, SW; Kammermeier, PJ | 1 |
| Chen, J; Cheng, Z; Chi, Z; Li, G; Pei, G; Wang, C; Wei, Q; Zhou, D | 1 |
| Hattori, Y; Kanno, M; Kitabatake, A; Kohya, T; Moriishi, K; Oguma, K; Sasaki, M; Tomita, F | 1 |
| Anand-Srivastava, MB; Ge, C; Palaparti, A | 1 |
| Tse, A; Tse, FW | 1 |
| del Carmen Medina, L; García-Sáinz, JA; Vázquez-Prado, J | 1 |
| Adams, B; Melliti, K; Meza, U | 1 |
| Amano, M; Fukata, Y; Kaibuchi, K; Shimokawa, H | 1 |
| Adams, BA; Melliti, K; Meza, U | 1 |
| Brkic-Koric, D; Pfitzer, G; Sonntag-Bensch, D | 1 |
| Alper, RH; Mize, AL | 1 |
| Henkel, AW; Henkel, MK; Vogt, TK | 1 |
46 other study(ies) available for staurosporine and guanosine 5'-o-(3-thiotriphosphate)
| Article | Year |
|---|---|
Functional localization of an exocytosis-triggering G-protein in human cytotoxic T lymphocytes.
Topics: Alkaloids; Cells, Cultured; Cyclosporine; Exocytosis; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Lymphocyte Activation; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; T-Lymphocytes, Cytotoxic; Tacrolimus | 1992 |
G-protein mediation in nociceptive signal transduction: an investigation into the excitatory action of bradykinin in a subpopulation of cultured rat sensory neurons.
Topics: Alkaloids; Animals; Animals, Newborn; Bradykinin; Cells, Cultured; Evoked Potentials; Ganglia, Spinal; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indomethacin; Kinetics; Masoprocol; Neurons, Afferent; Pain; Protein Kinase C; Rats; Rats, Wistar; Ryanodine; Signal Transduction; Staurosporine | 1992 |
Interaction between protein kinase C-dependent and G protein-dependent pathways in the regulation of natural killer cell granule exocytosis.
Topics: Alkaloids; Antigens, CD; Cell Line; Cytoplasmic Granules; Drug Synergism; Enzyme Activation; Exocytosis; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Killer Cells, Natural; Kinetics; Protein Kinase C; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Phosphorylation-dependent regulation of phospholipase A2 by G-proteins and Ca2+ in HL60 granulocytes.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Alkaloids; Arachidonic Acid; Calcium; Egtazic Acid; Enzyme Activation; Granulocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Homeostasis; Humans; Isoflurophate; Kinetics; Leukemia, Promyelocytic, Acute; Models, Biological; Pertussis Toxin; Phosphorylation; Protein Kinase C; Ribonucleotides; Staurosporine; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Synergistic activation of phospholipase D by protein kinase C- and G-protein-mediated pathways in streptolysin O-permeabilized HL60 cells.
Topics: Adenosine Triphosphate; Alkaloids; Bacterial Proteins; Cell Line; Cell Membrane Permeability; Drug Synergism; Enzyme Activation; Glycerophospholipids; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Neomycin; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Staurosporine; Streptolysins; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Phosphorylation of the spliced variant forms of the recombinant stimulatory guanine-nucleotide-binding regulatory protein (Gs alpha) by protein kinase C.
Topics: Alkaloids; Animals; Autoradiography; Blotting, Western; Brain; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Phosphorylation; Protein Kinase C; Rats; Recombinant Proteins; RNA Splicing; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Characterization of calcium-triggered secretion in permeabilized rat basophilic leukemia cells. Possible role of vectorially acting G proteins.
Topics: Alkaloids; Animals; Calcium; Cyclic AMP; Cytoplasmic Granules; Exocytosis; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hydrogen-Ion Concentration; Leukemia, Experimental; Microscopy, Electron; Protein Kinase C; Proteoglycans; Rats; Serotonin Antagonists; Staurosporine; Tumor Cells, Cultured | 1991 |
cGMP-gated conductance in retinal bipolar cells is suppressed by the photoreceptor transmitter.
Topics: Alkaloids; Aminobutyrates; Animals; Cyclic GMP; Dark Adaptation; Dipyridamole; Electric Conductivity; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Light; Neurotransmitter Agents; Phorbol Esters; Photoreceptor Cells; Retina; Staurosporine | 1991 |
Amylase release from streptolysin O-permeabilized pancreatic acini.
Topics: Alkaloids; Amylases; Animals; Bacterial Proteins; Calcium; Cell Membrane Permeability; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Male; Mice; Pancreas; Protein Kinase C; Staurosporine; Streptolysins; Tetradecanoylphorbol Acetate; Thionucleotides | 1990 |
Tyrosine phosphorylation and oxygen consumption induced by G proteins in neutrophils.
Topics: Adenine Nucleotides; Alkaloids; Aluminum; Aluminum Compounds; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Kinetics; Neutrophils; Oxygen Consumption; Pertussis Toxin; Phosphorylation; Phosphotyrosine; Protein Kinase C; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1991 |
Phorbol myristate acetate inhibits phosphoinositol lipid-specific phospholipase C activity via protein kinase C activation in conditions inducing differentiation in HL-60 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cell Differentiation; Cell Membrane; Clone Cells; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Isoquinolines; Leukemia, Myeloid; Lipid Metabolism; Piperazines; Protein Kinase C; Staurosporine; Streptolysins; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1991 |
Phospholipase D activation in a cell-free system from human neutrophils by phorbol 12-myristate 13-acetate and guanosine 5'-O-(3-thiotriphosphate). Activation is calcium dependent and requires protein factors in both the plasma membrane and cytosol.
Topics: Adenosine Triphosphate; Adult; Alkaloids; Calcium; Cell Membrane; Cell-Free System; Cytosol; Enzyme Activation; Ethanol; Glycerophospholipids; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrogen-Ion Concentration; Kinetics; Magnesium; Neutrophils; Phosphatidic Acids; Phospholipase D; Proteins; Staurosporine; Substrate Specificity; Tetradecanoylphorbol Acetate | 1991 |
Involvement of a guanine-nucleotide-binding protein-mediated mechanism in the enhancement of arachidonic acid liberation by phorbol 12-myristate 13-acetate and Ca2+ in saponin-permeabilized platelets.
Topics: Alkaloids; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cell Membrane Permeability; Chlorides; Diglycerides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Pertussis Toxin; Protein Kinase C; Rabbits; Saponins; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Full-length and truncated Kv1.3 K+ channels are modulated by 5-HT1c receptor activation and independently by PKC.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcineurin; Calmodulin-Binding Proteins; Charybdotoxin; Cloning, Molecular; Electric Stimulation; Female; Guanosine 5'-O-(3-Thiotriphosphate); Isoquinolines; Membrane Potentials; Mice; Oocytes; Pertussis Toxin; Phorbol Esters; Phosphoprotein Phosphatases; Piperazines; Potassium Channels; Protein Kinase C; Receptors, Serotonin; Recombinant Proteins; RNA, Complementary; Scorpion Venoms; Second Messenger Systems; Serotonin; Staurosporine; Transcription, Genetic; Virulence Factors, Bordetella; Xenopus laevis | 1993 |
Effects of parathyroid hormone on cytosolic calcium of rat adipocytes.
Topics: Adipocytes; Alkaloids; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Naphthalenes; Nifedipine; Parathyroid Hormone; Peptide Fragments; Pertussis Toxin; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Teriparatide; Verapamil; Virulence Factors, Bordetella | 1994 |
CCK-8-evoked cationic currents in substantia nigra dopaminergic neurons are mediated by InsP3-induced Ca2+ release.
Topics: Alkaloids; Animals; Calcium; Calcium Channels; Dopamine; Egtazic Acid; Evoked Potentials; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ion Channels; Neurons; Peptide Fragments; Pertussis Toxin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sincalide; Staurosporine; Substantia Nigra; Thionucleotides; Time Factors; Virulence Factors, Bordetella | 1994 |
Intracellular mechanisms of cytoplasmic Ca2+ oscillation in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Alkaloids; Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Calmodulin; Colforsin; Cyclic AMP; Cytoplasm; Egtazic Acid; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Megakaryocytes; Models, Biological; Oscillometry; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Trifluoperazine | 1993 |
Protein kinase C activates the non-selective cation channel in the rabbit portal vein.
Topics: Alkaloids; Animals; Chlorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Ion Channels; Male; Muscle, Smooth, Vascular; Nicardipine; Niflumic Acid; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Portal Vein; Protein Kinase C; Rabbits; Staurosporine; Virulence Factors, Bordetella | 1993 |
Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaloids; Animals; Arachidonic Acid; Calcimycin; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diglycerides; Diterpenes; Dopamine D2 Receptor Antagonists; Ergolines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Protein Kinase C; Quinpirole; Raclopride; Receptors, Dopamine D2; Recombinant Proteins; Salicylamides; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Potential role of protein phosphorylation in GTP-gamma-S-dependent activation of phospholipase D.
Topics: Adenosine Triphosphate; Alkaloids; Cell Line; Enzyme Activation; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Isoflavones; Phospholipase D; Phosphorylation; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
An elevation of cytosolic protein phosphorylation modulates trimeric G-protein regulation of secretory vesicle formation from the trans-Golgi network.
Topics: Alkaloids; Animals; Cytosol; Ethers, Cyclic; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Okadaic Acid; PC12 Cells; Phosphoproteins; Phosphorylation; Rats; Staurosporine; Vacuoles | 1994 |
Short-term desensitization of the angiotensin II receptor of bovine adrenal glomerulosa cells corresponds to a shift from a high to a low affinity state.
Topics: Aldosterone; Alkaloids; Angiotensin II; Animals; Biphenyl Compounds; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Imidazoles; Losartan; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Receptors, Angiotensin; Staurosporine; Tetrazoles; Time Factors; Zona Glomerulosa | 1994 |
Role of protein phosphorylation in the degranulation of electropermeabilized human neutrophils.
Topics: Adenosine Triphosphate; Alkaloids; Antigens, CD; Calcium; Cell Degranulation; Cytochalasin B; Deoxyglucose; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Neutrophils; Phosphorylation; Proteins; Staurosporine | 1994 |
Cross-desensitization of receptors for peptide chemoattractants. Characterization of a new form of leukocyte regulation.
Topics: Adenosine Triphosphate; Alkaloids; Calcium; Cell Membrane; Chemotaxis, Leukocyte; Cytochalasin B; Down-Regulation; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Neutrophils; Phospholipase D; Protein Kinase C; Receptor, Anaphylatoxin C5a; Receptors, Complement; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Protein kinase-independent inhibition of muscarinic K+ channels by staurosporine.
Topics: Adenylyl Imidodiphosphate; Alkaloids; Animals; Guanosine 5'-O-(3-Thiotriphosphate); Heart Atria; Myocardium; Potassium Channel Blockers; Protein Kinase Inhibitors; Protein Kinases; Rana catesbeiana; Receptors, Muscarinic; Staurosporine | 1994 |
Modulation by protein kinase C of arachidonic acid release from permeabilised myometrial cells of guinea pig uterus.
Topics: Alkaloids; Animals; Arachidonic Acid; Calcium; Cell Membrane Permeability; Cells, Cultured; Enzyme Activation; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Inositol Phosphates; Myometrium; Phospholipases A; Phospholipases A2; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1993 |
Guanine nucleotides activate multiple signaling pathways in permeabilized gastric chief cells. Evidence for GTP gamma S-induced calcium-independent pepsinogen secretion.
Topics: Alkaloids; Animals; Bacterial Proteins; Calcium; Carbachol; Cell Membrane Permeability; Cyclic AMP; Cytidine Diphosphate Diglycerides; Gastric Mucosa; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Male; Pepsinogens; Phorbol Esters; Phosphorylation; Protein Kinase C; Signal Transduction; Staurosporine; Streptolysins; Type C Phospholipases | 1993 |
Mastoparan stimulates insulin secretion from pancreatic beta-cells by effects at a late stage in the secretory pathway.
Topics: Adenosine Triphosphate; Alkaloids; Amino Acid Sequence; Animals; Calcium; Cell Membrane Permeability; Cyclic AMP; Enzyme Activation; Glucose; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Insulin; Insulin Secretion; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Molecular Sequence Data; Peptides; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rats; Signal Transduction; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thionucleotides; Wasp Venoms | 1993 |
Primary sites of actions of staurosporine and H-7 in the cascade of insulin action to glucose transport in rat adipocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adipose Tissue; Alkaloids; Animals; Binding Sites; Biological Transport; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Insulin; Isoquinolines; Male; Monosaccharide Transport Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Staurosporine | 1993 |
GTPgammaS-stimulated phospholipase D activation in human neutrophils occurs by protein kinase C-dependent and -independent pathways but not tyrosine kinases.
Topics: Alkaloids; Benzylidene Compounds; Cell Membrane Permeability; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydroquinones; In Vitro Techniques; Indoles; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Nitriles; Phospholipase D; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tyrphostins; Vanadates | 1996 |
Cross-desensitization among receptors for platelet activating factor and peptide chemoattractants. Evidence for independent regulatory pathways.
Topics: Amino Acid Sequence; Calcium; Chemotactic Factors; Egtazic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Interleukin-8; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Store-activated Ca2+ inflow in Xenopus laevis oocytes: inhibition by primaquine and evaluation of the role of membrane fusion.
Topics: Aniline Compounds; Animals; Calcium; Calcium Channels; Calmodulin-Binding Proteins; Cell Membrane; Cholera Toxin; Deferoxamine; Drosophila; Drosophila Proteins; Female; Fluorescent Dyes; Gadolinium; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Kinetics; Membrane Fusion; Membrane Proteins; Oocytes; Primaquine; Staurosporine; Transient Receptor Potential Channels; Xanthenes; Xenopus laevis | 1996 |
Activation of endothelin ETA receptors induces phosphorylation of alpha1b-adrenoreceptors in Rat-1 fibroblasts.
Topics: Animals; Calcium; Cell Line; Cell Membrane; Cricetinae; Endothelin Receptor Antagonists; Endothelin-1; Fibroblasts; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Norepinephrine; Peptides, Cyclic; Phosphorylation; Rats; Receptor, Endothelin A; Receptors, Adrenergic, alpha-1; Receptors, Endothelin; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Characteristics of protein-kinase-C- and ADP-ribosylation-factor-stimulated phospholipase D activities in human embryonic kidney cells.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Cell Line; Digitonin; GTP-Binding Proteins; GTPase-Activating Proteins; Guanine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Isoenzymes; Kidney; Neomycin; Permeability; Phospholipase D; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Facilitation of L-type calcium current in thalamic neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Electrophysiology; Enzyme Inhibitors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons; Okadaic Acid; omega-Conotoxin GVIA; omega-Conotoxins; Peptides; Rats; Staurosporine; Thalamic Nuclei; Thionucleotides; Time Factors | 1998 |
The C-truncated delta-opioid receptor underwent agonist-dependent activation and desensitization.
Topics: Animals; Cell Membrane; CHO Cells; Cricetinae; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Peptide Fragments; Phosphorylation; Polymerase Chain Reaction; Protein Kinase Inhibitors; Receptors, Opioid, delta; Staurosporine; Structure-Activity Relationship; Transfection | 1998 |
Tyrosine phosphorylation as a convergent pathway of heterotrimeric G protein- and rho protein-mediated Ca2+ sensitization of smooth muscle of rabbit mesenteric artery.
Topics: Adenosine Diphosphate; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcium; Carcinogens; Dimerization; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; rho GTP-Binding Proteins; Ribose; Staurosporine; Tyrosine; Tyrphostins; Vasoconstrictor Agents | 1998 |
Angiotensin II enhances the expression of Gialpha in A10 cells (smooth muscle): relationship with adenylyl cyclase activity.
Topics: Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cell Line; Colforsin; Dactinomycin; Dose-Response Relationship, Drug; Drug Interactions; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Muscle, Smooth, Vascular; Peptide Fragments; Protein Kinase C; Rats; Staurosporine | 1999 |
Stimulation of Ca(2+)-independent exocytosis in rat pituitary gonadotrophs by G-protein.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aluminum Compounds; Animals; Calcium; Calcium-Transporting ATPases; Cyclic AMP; Cytoplasmic Granules; Cytosol; Egtazic Acid; Enzyme Inhibitors; Exocytosis; Fluorides; Fluorometry; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Male; Patch-Clamp Techniques; Photolysis; Pituitary Gland, Anterior; Protein Kinase C; Rats; Staurosporine | 2000 |
Cross-talk between receptors with intrinsic tyrosine kinase activity and alpha1b-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Androstadienes; Animals; Cell Line; Cell Membrane; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblasts; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Norepinephrine; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet-Derived Growth Factor; Protein Binding; Protein Kinase C; Protein-Tyrosine Kinases; Quinazolines; Rats; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, alpha-1; Staurosporine; Time Factors; Transfection; Tyrphostins; Wortmannin | 2000 |
Muscarinic stimulation of alpha1E Ca channels is selectively blocked by the effector antagonist function of RGS2 and phospholipase C-beta1.
Topics: Animals; Brain; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, R-Type; Carbachol; Cation Transport Proteins; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ion Transport; Isoenzymes; Muscarinic Agonists; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Pertussis Toxin; Phospholipase C beta; Rabbits; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; RGS Proteins; Signal Transduction; Staurosporine; Transfection; Type C Phospholipases; Virulence Factors, Bordetella | 2000 |
Purification and in vitro activity of Rho-associated kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Baculoviridae; Catalytic Domain; Cattle; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Signaling Peptides and Proteins; Protein Serine-Threonine Kinases; Pyridines; Recombinant Fusion Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Staurosporine | 2000 |
RGS2 blocks slow muscarinic inhibition of N-type Ca(2+) channels reconstituted in a human cell line.
Topics: Calcium Channels, N-Type; Carbachol; Cell Line; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Muscarinic Agonists; Pertussis Toxin; RGS Proteins; Staurosporine; Time Factors; Virulence Factors, Bordetella | 2001 |
Thiophosphorylation-induced Ca(2+) sensitization of guinea-pig ileum contractility is not mediated by Rho-associated kinase.
Topics: Actin Cytoskeleton; Adenosine Triphosphate; Amides; Animals; Calcium; Carbachol; Drug Synergism; Enzyme Inhibitors; Female; Gastrointestinal Motility; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Staurosporine; Sulfhydryl Compounds; Sulfur | 2001 |
Rapid uncoupling of serotonin-1A receptors in rat hippocampus by 17beta-estradiol in vitro requires protein kinases A and C.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Carbazoles; Cell Membrane; Culture Techniques; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Indoles; Naphthalenes; Ovariectomy; Phosphorylation; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Staurosporine | 2002 |
Staurosporine restores GTPgammaS induced block of rapid endocytosis in chromaffin cells.
Topics: Adrenal Medulla; Animals; Cattle; Cells, Cultured; Chromaffin Cells; Endocytosis; Exocytosis; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Staurosporine | 2004 |