staurosporine has been researched along with epidermal growth factor in 71 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (5.63) | 18.7374 |
| 1990's | 52 (73.24) | 18.2507 |
| 2000's | 15 (21.13) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, NG | 1 |
| Andrejauskas-Buchdunger, E; Regenass, U | 1 |
| Kobayashi, T | 1 |
| Abe, K; Saito, H; Takayanagi, M | 1 |
| al-Awqati, Q; Herzlinger, D; Koseki, C | 1 |
| Ikeda, K; Kikuchi, T; Matsumoto, T; Morimoto, K; Nakano, T; Ogata, E; Okazaki, R; Sakamoto, A; Urakawa, K | 1 |
| Lane, HA; Susa, M; Thomas, G; Vulević, D | 1 |
| Knopf, JL; Lin, AY; Lin, LL | 1 |
| Dlugosz, AA; Yuspa, SH | 1 |
| Friedman, B; Fujiki, H; Rosner, MR | 1 |
| Kikuchi, T; Tamm, I | 1 |
| Johnson, AL; Tilly, JL | 1 |
| Cao, XM; Guy, GR; Sukhatme, VP; Tan, YH | 1 |
| Fox, MT; Hughes, JP; Prentice, DA | 1 |
| Ajakane, M; Baudet, V; Bellevergue, P; Boissin, P; Boursier, E; Coste, H; Grand-Perret, T; Loriolle, F; Pianetti, P; Toullec, D | 1 |
| Moore, JJ; Moore, RM; Vander Kooy, D | 1 |
| Ide, T; Tsuji, K; Ueno, A | 1 |
| Burns, KD; Harris, RC; Homma, T | 1 |
| Fertel, RH; Gabbe, SG; Iams, JD; Kniss, DA; Mershon, J; Sonek, J; Su, HC; Waxman, M | 1 |
| Goodrum, DD; Sachs, G; Wheeler, LA | 1 |
| Bjorge, JD; Kudlow, JE; Mills, GB; Paterson, AJ | 1 |
| Breyer, JA; Breyer, MD; Jacobson, HR | 1 |
| Blumberg, PM; Jeng, AY; Sako, T; Tauber, AI; Yuspa, SH | 1 |
| Eppenberger, U; Fabbro, D; Küng, W; Matter, A; Novak-Hofer, I | 1 |
| Eling, TE; Hamasaki, Y | 1 |
| Clemmons, DR; McCusker, RH | 1 |
| Asaoka, Y; Chang, WC; Liu, YW; Suzuki, H; Yamamoto, S; Yoshimoto, T | 1 |
| Bradshaw, RA; Raffioni, S | 1 |
| Goishi, K; Higashiyama, S; Ishikawa, M; Klagsbrun, M; Mekada, E; Nakano, N; Taniguchi, N; Umata, T | 1 |
| Fukami, J; Ide, T; Tsuji, K; Ueno, A | 1 |
| Aharon, A; Kraiem, Z; Sadeh, O; Yosef, M | 1 |
| Godson, C; Li, SL; Prentki, M; Roche, E; Schlegel, W; Zhao, SJ | 1 |
| Bowen, W; Michalopoulos, GK; Petersen, B; Yee, CJ; Zarnegar, R | 1 |
| Bonney, RC; Franks, S; Watson, H | 1 |
| Clark, S; Dunlop, M; Keogh, R | 1 |
| Bianchi, C; Chen, HC; Endege, W; Higashiyama, S; Lai, YH; Lee, YJ; Perrella, MA; Shin, SJ; Tan, MS; Tsai, JC | 1 |
| Lee, YJ; Shin, SJ; Tan, MS; Tsai, JH | 1 |
| Foster, DA; Jiang, YW; Song, J | 1 |
| Connor, P; Gretz, HF; Lelle, RJ; Menon, KM; Pearl, M; Roberts, JA; Talavera, F | 1 |
| Clark, OH; Duh, QY; Hoelting, T; Siperstein, AE; Tezelman, S | 1 |
| Hordijk, PL; Moolenaar, WH; van Corven, EJ; Verlaan, I | 1 |
| Gañan, Y; Garcia-Martinez, V; Hurle, JM; Macias, D | 1 |
| Davis, BB; Thomas, DJ; Zenser, TV | 1 |
| Birkedal-Hansen, B; Birkedal-Hansen, H; Lyons, JG; Pierson, MC; Whitelock, JM | 1 |
| Boniece, IR; Wagner, JA | 1 |
| DelValle, J; Osburn, J; Wang, L; Wilson, EJ | 1 |
| Blok, LJ; Grossmann, ME; Perry, JE; Tindall, DJ | 1 |
| Djakiew, D; Zolfaghari, A | 1 |
| Bar-Shalom, I; Beery, R; Geier, A; Haimsohn, M; Hemi, R; Karasik, A; Lunenfeld, B; Malik, Z | 1 |
| Kleijn, M; Korthout, MM; Thomas, AA; Voorma, HO | 1 |
| Benahmed, M; Kolodié, L; Le Magueresse-Battistoni, B; Morera, AM; Pernod, G | 1 |
| Atsumi, T; Hosoi, K; Kurihara, K; Shioda, Y; Sugita, K; Ueha, T | 1 |
| Goretzki, L; Mueller, BM | 1 |
| Higashiyama, S; Ito, N; Kawata, S; Kiso, S; Matsuzawa, Y; Nakagawa, T; Tamura, S; Taniguchi, N; Tsushima, H | 1 |
| Butler, K; Del Valle, J; Hare, B; Hoeltzel, M; Todisco, A; Wang, LD; Wang, M | 1 |
| Lan, L; Wong, NS | 1 |
| Chang, C; Hu, C; Leu, CM | 1 |
| del Carmen Medina, L; García-Sáinz, JA; Vázquez-Prado, J | 1 |
| Haugen, KE; Johannessen, LE; Madshus, IH; Stang, E; østvold, AC | 1 |
| Chen, JS; Song, JG | 1 |
| Fong, WF; Lam, W; Leung, CH; Wong, NS; Yang, MS; Zhuang, WJ | 1 |
| Baker, PN; Barratt, S; Crocker, IP; Kaur, M | 1 |
| Dickenson, JM | 1 |
| Akita, Y; Gutierrez-Hartmann, A; Manning, N; Pickett, CA | 1 |
| Cusinato, F; Luciani, S; Nardelli, GB; Trevisi, L; Vinci, MC; Visentin, B | 1 |
| Li, C; Schwartz, SM; Shah, PK; Sharifi, BG; Wallner, K; Wu, KJ | 1 |
| Herzog, V; Kirfel, G; Siemes, C; Wehner, S | 1 |
| Calvo-Ochoa, E; García-Sáinz, JA; Kalashnikova, EV; Reyes-Cruz, G; Rodríguez-Pérez, CE; Romero-Avila, MT | 1 |
| Adolfo García-Sáinz, J; Alcántara-Hernández, R | 1 |
| Binge, LC; Gurung, R; Hakim, S; Horan, KA; Ivetac, I; Majerus, PW; Mitchell, CA; Sheffield, DA; Tiganis, T | 1 |
| Blick, T; Hugo, HJ; Newgreen, DF; Thompson, EW; Wafai, R | 1 |
71 other study(ies) available for staurosporine and epidermal growth factor
| Article | Year |
|---|---|
Growth hormone activates mitogen-activated protein kinase and S6 kinase and promotes intracellular tyrosine phosphorylation in 3T3-F442A preadipocytes.
Topics: 3T3 Cells; Adipose Tissue; Alkaloids; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Epidermal Growth Factor; Growth Hormone; Kinetics; Mice; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Kinases; Ribosomal Protein S6 Kinases; Staurosporine; Tyrosine | 1992 |
Differential inhibition of the epidermal growth factor-, platelet-derived growth factor-, and protein kinase C-mediated signal transduction pathways by the staurosporine derivative CGP 41251.
Topics: 3T3 Cells; Alkaloids; Animals; Antineoplastic Agents; Cells, Cultured; Epidermal Growth Factor; Gene Expression; Genes, fos; Mice; Mice, Inbred BALB C; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Receptors, Platelet-Derived Growth Factor; RNA, Messenger; Signal Transduction; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1992 |
[Sulfolipids and glycolipid sulfotransferases in a human renal cell carcinoma cell line].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Carcinoma, Renal Cell; Epidermal Growth Factor; Humans; Isoquinolines; Kidney Neoplasms; Lipid Metabolism; Lipids; Piperazines; Protein Kinase C; Staurosporine; Sulfotransferases; Sulfurtransferases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Neurotrophic effects of epidermal growth factor on cultured brain neurons are blocked by protein kinase inhibitors.
Topics: Alkaloids; Animals; Brain; Carbazoles; Cell Survival; Cells, Cultured; Epidermal Growth Factor; Indole Alkaloids; Neurons; Protein Kinase C; Rats; Recombinant Proteins; Staurosporine | 1992 |
Apoptosis in metanephric development.
Topics: Alkaloids; Animals; Apoptosis; Cycloheximide; Dactinomycin; Embryonic Induction; Epidermal Growth Factor; Epidermis; Mesoderm; Nephrons; Organ Culture Techniques; Phorbol Esters; Protein Kinase C; Rats; Spinal Cord; Staurosporine; Ureter | 1992 |
Transcriptional activation of c-fos and c-jun protooncogenes by serum growth factors in osteoblast-like MC3T3-E1 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Cell Differentiation; Cycloheximide; Dactinomycin; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression Regulation; Growth Substances; Insulin-Like Growth Factor I; Isoquinolines; Mice; Osteoblasts; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA, Messenger; Staurosporine; Transforming Growth Factor beta | 1992 |
Inhibition or down-regulation of protein kinase C attenuates late phase p70s6k activation induced by epidermal growth factor but not by platelet-derived growth factor or insulin.
Topics: 3T3 Cells; Alkaloids; Animals; Autoradiography; Down-Regulation; Epidermal Growth Factor; Insulin; Mice; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinase C; Protein Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Arachidonic Acid; Calcimycin; Calcium; CHO Cells; Cricetinae; Cytosol; Enzyme Activation; Epidermal Growth Factor; In Vitro Techniques; Phospholipases A; Phospholipases A2; Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
Staurosporine induces protein kinase C agonist effects and maturation of normal and neoplastic mouse keratinocytes in vitro.
Topics: Alkaloids; Animals; Carcinogenicity Tests; Cell Differentiation; Dimethyl Sulfoxide; Enzyme Induction; Epidermal Growth Factor; Keratinocytes; Mice; Mice, Inbred BALB C; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; RNA, Messenger; Skin Neoplasms; Staurosporine; Tetradecanoylphorbol Acetate; Transglutaminases; Tumor Cells, Cultured | 1991 |
Regulation of the epidermal growth factor receptor by growth-modulating agents: effects of staurosporine, a protein kinase inhibitor.
Topics: Alkaloids; Animals; Calcimycin; Epidermal Growth Factor; ErbB Receptors; Humans; Mice; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Tumor Cells, Cultured; Tyrosine | 1990 |
Activation of signal transduction pathways protects quiescent Balb/c-3T3 fibroblasts against death due to serum deprivation.
Topics: 2-Aminopurine; Alkaloids; Animals; Cell Division; Cell Survival; Cells, Cultured; Epidermal Growth Factor; Fibroblasts; Insulin; Insulin-Like Growth Factor I; Mice; Mice, Inbred BALB C; Neutral Red; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Proteins; RNA; S Phase; Second Messenger Systems; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Second messenger pathways mediating chicken luteinizing hormone secretion from dispersed pituitary cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Arachidonic Acids; Calcimycin; Calcium; Carcinogens; Chickens; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Pituitary Gland; Protein Kinase C; Second Messenger Systems; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transforming Growth Factor alpha | 1991 |
Regulation of the Egr-1 gene by tumor necrosis factor and interferons in primary human fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Blotting, Northern; Blotting, Western; DNA; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; HeLa Cells; Humans; Interferon-gamma; Isoquinolines; Kinetics; Mice; Phosphorylation; Piperazines; RNA, Messenger; Staurosporine; Sulfonamides; Thymidine; Tumor Necrosis Factor-alpha | 1992 |
Increases in p11 and annexin II proteins correlate with differentiation in the PC12 pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Alkaloids; Animals; Annexin A2; Annexins; Calcium-Binding Proteins; Cell Differentiation; Cell Line; Epidermal Growth Factor; Kinetics; Membrane Proteins; Nerve Growth Factors; Peptide Biosynthesis; Peptides; Pheochromocytoma; Protein Kinase C; Rats; S100 Proteins; Staurosporine | 1991 |
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Blood Platelets; Bombesin; Collagen; DNA; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Fibroblasts; Humans; Indoles; Maleimides; Mice; Phorbol 12,13-Dibutyrate; Phosphorylation; Platelet Aggregation; Protein Kinase C; Staurosporine; Structure-Activity Relationship; Thymidine; Vimentin | 1991 |
Protein kinase-C activation is required for oxytocin-induced prostaglandin production in human amnion cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Isoquinolines; Oxytocin; Phorbol Esters; Piperazines; Pregnancy; Protein Kinase C; RNA, Messenger; Staurosporine; Time Factors; Type C Phospholipases | 1991 |
Dual effect of protein kinase C on the induction of DNA synthesis by colcemid in G0-arrested human diploid fibroblasts.
Topics: Alkaloids; Blotting, Northern; Cell Line; Colchicine; Demecolcine; DNA; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Humans; Protein Kinase C; Resting Phase, Cell Cycle; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Agonist stimulation of Na+/K+/Cl- cotransport in rat glomerular mesangial cells. Evidence for protein kinase C-dependent and Ca2+/calmodulin-dependent pathways.
Topics: Alkaloids; Amino Acid Sequence; Angiotensin II; Animals; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cells, Cultured; Chlorides; Epidermal Growth Factor; Glomerular Mesangium; Kinetics; Molecular Sequence Data; Oligopeptides; Pertussis Toxin; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Sodium; Sodium-Potassium-Chloride Symporters; Staurosporine; Substrate Specificity; Sulfonamides; Thrombin; Virulence Factors, Bordetella | 1990 |
Evidence of a role for protein kinase C in epidermal growth factor-induced prostaglandin E2 synthesis in amnion cells.
Topics: Alkaloids; Amnion; Cell Line; Dinoprostone; Down-Regulation; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Pregnancy; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Role of protein kinase C in the regulation of cytosolic Ca2+ in A431 cells: separation of growth factor and bradykinin pathways.
Topics: Alkaloids; Bradykinin; Calcium; Cytosol; Down-Regulation; Epidermal Growth Factor; Humans; Ionomycin; Manganese; Protein Kinase C; Pyrimidinones; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thiazoles; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1990 |
Inhibition of stimulus-dependent epidermal growth factor receptor and transforming growth factor-alpha mRNA accumulation by the protein kinase C inhibitor staurosporine.
Topics: Alkaloids; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation; Humans; Phosphotyrosine; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Tumor Cells, Cultured; Tyrosine | 1989 |
Epidermal growth factor inhibits the hydroosmotic effect of vasopressin in the isolated perfused rabbit cortical collecting tubule.
Topics: Alkaloids; Animals; Arginine Vasopressin; Cyclic AMP; Electric Conductivity; Epidermal Growth Factor; Epithelium; Female; Indomethacin; Kidney Cortex; Kidney Tubules; Kidney Tubules, Collecting; Osmolar Concentration; Perfusion; Rabbits; Staurosporine; Thionucleotides; Water-Electrolyte Balance | 1988 |
Contrasting actions of staurosporine, a protein kinase C inhibitor, on human neutrophils and primary mouse epidermal cells.
Topics: Alkaloids; Animals; Cells, Cultured; Epidermal Growth Factor; Epidermis; Humans; Mice; Mice, Inbred BALB C; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Ornithine Decarboxylase; Protein Kinase C; Staurosporine; Transglutaminases | 1988 |
Regulation of ribosomal protein S6 kinase in human mammary tumor cells: effect of estrogen, growth factors and phorbol ester.
Topics: Alkaloids; Breast Neoplasms; Enzyme Activation; Epidermal Growth Factor; Estradiol; Growth Substances; Humans; Insulin; Phorbol Esters; Phosphorylation; Protein Kinases; Ribosomal Protein S6 Kinases; Ribosomal Proteins; Staurosporine; Tumor Cells, Cultured | 1988 |
EGF and TPA stimulate de novo synthesis of PGHS-1 and PGHS-2 through different signal transduction pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Line, Transformed; Cinnamates; Dinoprostone; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium; Isoquinolines; Piperazines; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Trachea | 1995 |
Effects of cytokines on insulin-like growth factor-binding protein secretion by muscle cells in vitro.
Topics: Alkaloids; Animals; Blotting, Western; Carrier Proteins; Cell Line; Culture Media, Conditioned; Cytokines; Epidermal Growth Factor; Fibroblast Growth Factor 2; Insulin; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Mice; Muscle, Smooth, Vascular; Muscles; Rats; Staurosporine; Suramin; Swine; Thrombin; Transforming Growth Factor beta | 1994 |
Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells.
Topics: Alkaloids; Arachidonate 12-Lipoxygenase; Carcinoma, Squamous Cell; Diglycerides; Enzyme Induction; Epidermal Growth Factor; Humans; Naphthalenes; Phosphatidylinositol Phosphates; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Staurosporine causes epidermal growth factor to induce differentiation in PC12 cells via receptor up-regulation.
Topics: Alkaloids; Animals; Blotting, Northern; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Kinetics; Mice; Neurites; PC12 Cells; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Rats; RNA, Messenger; Staurosporine; Tyrosine; Up-Regulation | 1995 |
Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acids; Animals; Anti-Bacterial Agents; Cell Membrane; Chlorocebus aethiops; Diphtheria Toxin; DNA; Endosomes; Enzyme Inhibitors; Epidermal Growth Factor; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Isoquinolines; Kinetics; Macrolides; Molecular Weight; Piperazines; Protein Kinase C; Protein Precursors; Protein Processing, Post-Translational; Staurosporine; Tetradecanoylphorbol Acetate; Vero Cells | 1995 |
Transforming growth factor-beta 1 has both promoting and inhibiting effects on induction of DNA synthesis in human fibroblasts.
Topics: Alkaloids; DNA; DNA-Binding Proteins; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; GTP-Binding Proteins; Humans; Pertussis Toxin; Protein Kinase C; Resting Phase, Cell Cycle; Signal Transduction; Staurosporine; Transforming Growth Factor beta; Virulence Factors, Bordetella | 1995 |
Mutual antagonistic interactions between the thyrotropin (adenosine 3',5'-monophosphate) and protein kinase C/epidermal growth factor (tyrosine kinase) pathways in cell proliferation and differentiation of cultured human thyroid follicles.
Topics: Alkaloids; Cell Differentiation; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Epidermal Growth Factor; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Second Messenger Systems; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1995 |
Induction of c-fos in pituitary cells by thyrotrophin-releasing hormone and phorbol 12-myristate 13-acetate depends upon Ca2+ influx.
Topics: Alkaloids; Animals; Calcium; Cell Line; Culture Media, Serum-Free; Cytoplasm; Down-Regulation; Edetic Acid; Egtazic Acid; Epidermal Growth Factor; Gene Expression Regulation; Genes, fos; Phorbol 12,13-Dibutyrate; Pituitary Gland; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Transcription, Genetic | 1994 |
Distinct morphological and mito-inhibitory effects induced by TGF-beta 1, HGF and EGF on mouse, rat and human hepatocytes.
Topics: Alkaloids; Animals; Cell Size; Cells, Cultured; Cycloheximide; Cytoskeletal Proteins; Cytoskeleton; DNA Replication; Dose-Response Relationship, Drug; Epidermal Growth Factor; Female; Genistein; Hepatocyte Growth Factor; Humans; Isoflavones; Liver; Male; Mice; Rats; Rats, Inbred F344; Staurosporine; Sulfonamides; Transforming Growth Factor beta | 1994 |
The epidermal growth factor receptor in the human endometrial adenocarcinoma cell line HEC-1-B.
Topics: Adenocarcinoma; Alkaloids; Binding Sites; Endometrial Neoplasms; Epidermal Growth Factor; ErbB Receptors; Estradiol; Female; Humans; Kinetics; Progesterone; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
The role of protein kinase C in arachidonic acid release and prostaglandin E production from CHO cells transfected with EGF receptors.
Topics: Alkaloids; Animals; Arachidonic Acid; CHO Cells; Cricetinae; Epidermal Growth Factor; ErbB Receptors; Phospholipases A; Phospholipases A2; Prostaglandins E; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1994 |
Induction of heparin-binding epidermal growth factor-like growth factor mRNA by protein kinase C activators.
Topics: Alkaloids; Animals; Cell Line; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation; Glomerular Mesangium; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 1994 |
Regulation of heparin binding-epidermal growth factor like growth factor gene expression by LDL and oxidized-LDL in rat mesangial cells.
Topics: Alkaloids; Animals; Blotting, Northern; Epidermal Growth Factor; Gene Expression Regulation; Glomerular Mesangium; Heparin; Kinetics; Lipoproteins, LDL; Male; Oxidation-Reduction; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Epidermal growth factor induces the production of biologically distinguishable diglyceride species from phosphatidylinositol and phosphatidylcholine via the independent activation of type C and type D phospholipases.
Topics: Alkaloids; Animals; Cell Line; Diglycerides; Epidermal Growth Factor; Humans; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Staurosporine; Time Factors; Type C Phospholipases | 1994 |
Protein kinase C-dependent and -independent pathways mediate epidermal growth factor (EGF) effects in human endometrial adenocarcinoma cell line KLE.
Topics: Adenocarcinoma; Alkaloids; Animals; Cell Division; Dose-Response Relationship, Drug; Endometrial Neoplasms; Epidermal Growth Factor; Female; Humans; Mice; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured | 1994 |
Thyrotropin stimulates invasion and growth of follicular thyroid cancer cells via PKC- rather than PKA-activation.
Topics: Alkaloids; Cell Division; Cholera Toxin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Humans; Neoplasm Invasiveness; Pertussis Toxin; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Thyrotropin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Protein tyrosine phosphorylation induced by lysophosphatidic acid in Rat-1 fibroblasts. Evidence that phosphorylation of map kinase is mediated by the Gi-p21ras pathway.
Topics: Adenylate Cyclase Toxin; Alkaloids; Animals; Cell Adhesion Molecules; Cells, Cultured; Endothelins; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Proteins; Kinetics; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Oncogene Protein p21(ras); Pertussis Toxin; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Staurosporine; Tyrosine; Virulence Factors, Bordetella | 1994 |
In vivo experimental induction of interdigital tissue chondrogenesis in the avian limb bud results in the formation of extradigits. Effects of local microinjection of staurosporine, zinc chloride and growth factors.
Topics: Alkaloids; Animals; Cartilage; Chick Embryo; Chlorides; Epidermal Growth Factor; Hindlimb; Mesoderm; Microinjections; Protein Kinase C; Staurosporine; Toes; Transforming Growth Factor beta; Zinc Compounds | 1993 |
Cyclic adenosine monophosphate response in primary and subcultured bladder epithelial cells: inhibition by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Alkaloids; Animals; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Dogs; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Epithelium; Indomethacin; Models, Biological; Protein Kinase C; Second Messenger Systems; Signal Transduction; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Urinary Bladder | 1993 |
Interleukin-1 beta and transforming growth factor-alpha/epidermal growth factor induce expression of M(r) 95,000 type IV collagenase/gelatinase and interstitial fibroblast-type collagenase by rat mucosal keratinocytes.
Topics: Alkaloids; Animals; Cell Line; Collagenases; Dexamethasone; Endopeptidases; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; Fibroblasts; Gelatinases; Interleukin-1; Keratinocytes; Mammary Neoplasms, Experimental; Molecular Weight; Mouth Mucosa; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1993 |
Growth factors protect PC12 cells against ischemia by a mechanism that is independent of PKA, PKC, and protein synthesis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Anisomycin; Cell Hypoxia; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Fibroblast Growth Factor 2; Ischemia; Isoquinolines; Kinetics; Models, Biological; Neoplasm Proteins; Nerve Growth Factors; PC12 Cells; Phosphorylation; Piperazines; Protein Kinase C; Staurosporine; Time Factors | 1993 |
Epidermal growth factor inhibits carbachol-stimulated canine parietal cell function via protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminopyrine; Animals; Calcium; Carbachol; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dogs; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Gastric Acid; Inositol 1,4,5-Trisphosphate; Isoquinolines; Parasympathomimetics; Parietal Cells, Gastric; Piperazines; Protein Kinase C; Receptors, Muscarinic; Staurosporine; Sulfonamides | 1996 |
Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation.
Topics: Alkaloids; Amino Acid Sequence; Androgens; Animals; Base Sequence; Binding Sites; Carcinoma; Cell Cycle; Consensus Sequence; DNA; Early Growth Response Transcription Factors; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Transcription Factors; Male; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Kinase C; Rabbits; Rats; Regulatory Sequences, Nucleic Acid; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity; Staurosporine; Transcription Factors; Zinc Fingers | 1995 |
Inhibition of chemomigration of a human prostatic carcinoma cell (TSU-pr1) line by inhibition of epidermal growth factor receptor function.
Topics: Alkaloids; Antibodies, Monoclonal; Carbazoles; Carcinogens; Carcinoma; Cell Movement; Dimethyl Sulfoxide; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Immunoblotting; Indole Alkaloids; Male; Neoplasm Metastasis; Phosphorylation; Prostatic Neoplasms; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 1996 |
Induction of apoptosis in MDA-231 cells by protein synthesis inhibitors is suppressed by multiple agents.
Topics: Alkaloids; Apoptosis; Breast Neoplasms; Cycloheximide; DNA; Epidermal Growth Factor; Female; Humans; Protein Biosynthesis; Protein Synthesis Inhibitors; Ricin; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Phosphorylation of the eIF4E-binding protein PHAS-I after exposure of PC12 cells to EGF and NGF.
Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Enzyme Inhibitors; Epidermal Growth Factor; Eukaryotic Initiation Factor-4E; Immunophilins; Intracellular Signaling Peptides and Proteins; Nerve Growth Factors; PC12 Cells; Peptide Initiation Factors; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Polyenes; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Staurosporine; TOR Serine-Threonine Kinases; Wortmannin | 1996 |
Tumor necrosis factor-alpha regulates plasminogen activator inhibitor-1 in rat testicular peritubular cells.
Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; Isoflavones; Male; Plasminogen Activator Inhibitor 1; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Staurosporine; Testis; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Up-Regulation | 1997 |
ATP- and EGF-stimulated phosphatidulinositol synthesis by two different pathways, phospholipase D and diacylglycerol kinase, in A-431 epidermoid carcinoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Bradykinin; Calcimycin; Calcium; Carcinoma, Squamous Cell; Chelating Agents; Choline; Diacylglycerol Kinase; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Ionophores; Neoplasm Proteins; Pertussis Toxin; Phosphatidic Acids; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Pyrimidinones; Receptors, Purinergic P2; Signal Transduction; Staurosporine; Sulfonamides; Thiazoles; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Receptor-mediated endocytosis of urokinase-type plasminogen activator is regulated by cAMP-dependent protein kinase.
Topics: Adenoviruses, Human; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endocytosis; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; Humans; Indole Alkaloids; Indoles; Isoflavones; Isoquinolines; Lactoferrin; Low Density Lipoprotein Receptor-Related Protein-1; Maleimides; Melanoma; Naphthalenes; Phenols; Protein Kinase C; Receptors, Immunologic; Signal Transduction; Staurosporine; Sulfonamides; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1997 |
Regulation of heparin-binding EGF-like growth factor expression by phorbol ester in a human hepatoma-derived cell line.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Hepatocellular; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Heparin; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Naphthalenes; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Activation of the human histamine H2 receptor is linked to cell proliferation and c-fos gene transcription.
Topics: Cell Division; Cell Line; Cimetidine; Cloning, Molecular; Colforsin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; Epinephrine; Genes, fos; Genes, Reporter; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; Luciferases; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins c-fos; Receptors, Histamine H2; Recombinant Fusion Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1997 |
Phosphatidylinositol 3-kinase and protein kinase C are required for the inhibition of caspase activity by epidermal growth factor.
Topics: Alkaloids; Androstadienes; Apoptosis; Benzophenanthridines; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Chromatin; Chromones; DNA Fragmentation; Enzyme Precursors; Epidermal Growth Factor; Flow Cytometry; Humans; Indoles; Maleimides; Molecular Weight; Morpholines; Phenanthridines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin | 1999 |
Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway.
Topics: Androstadienes; Apoptosis; Carcinoma; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA, Antisense; Epidermal Growth Factor; ErbB Receptors; Esophageal Neoplasms; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; Staurosporine; Transfection; Tumor Cells, Cultured; Wortmannin | 2000 |
Cross-talk between receptors with intrinsic tyrosine kinase activity and alpha1b-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Androstadienes; Animals; Cell Line; Cell Membrane; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblasts; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Norepinephrine; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet-Derived Growth Factor; Protein Binding; Protein Kinase C; Protein-Tyrosine Kinases; Quinazolines; Rats; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, alpha-1; Staurosporine; Time Factors; Transfection; Tyrphostins; Wortmannin | 2000 |
Heterodimerization of the epidermal-growth-factor (EGF) receptor and ErbB2 and the affinity of EGF binding are regulated by different mechanisms.
Topics: Dimerization; Dynamins; Endocytosis; Epidermal Growth Factor; ErbB Receptors; GTP Phosphohydrolases; HeLa Cells; Humans; Phosphoamino Acids; Phosphorylation; Protein Binding; Receptor, ErbB-2; Staurosporine; Tetradecanoylphorbol Acetate | 2001 |
Bradykinin induces protein kinase C-dependent activation of phospholipase D in A-431 cells.
Topics: Acetophenones; Benzopyrans; Bradykinin; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Immunoblotting; Indoles; Isoenzymes; Kinetics; Maleimides; Phospholipase D; Phospholipids; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
PKCdelta-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF.
Topics: Acetophenones; Benzopyrans; Cell Division; Cycloheximide; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; GADD45 Proteins; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Kinetics; Leupeptins; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Proteins; Pyridines; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ubiquitins | 2001 |
The in-vitro characterization of induced apoptosis in placental cytotrophoblasts and syncytiotrophoblasts.
Topics: Acridine Orange; Adenosine Diphosphate; Adenosine Triphosphate; Annexin A5; Apoptosis; Cells, Cultured; Dexamethasone; Epidermal Growth Factor; Ethidium; Female; Fluorescent Dyes; Glucocorticoids; Humans; In Situ Nick-End Labeling; Indicators and Reagents; Interferon-gamma; Microscopy, Fluorescence; Oxygen; Pregnancy; Propidium; Staurosporine; Trophoblasts; Tumor Necrosis Factor-alpha | 2001 |
Stimulation of protein kinase B and p70 S6 kinase by the histamine H1 receptor in DDT1MF-2 smooth muscle cells.
Topics: Animals; Caspase 3; Caspases; Cell Division; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Enzyme Activators; Epidermal Growth Factor; Histamine; Male; Muscle, Smooth; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Histamine H1; Ribosomal Protein S6 Kinases; Staurosporine | 2002 |
Role of specific protein kinase C isozymes in mediating epidermal growth factor, thyrotropin-releasing hormone, and phorbol ester regulation of the rat prolactin promoter in GH4/GH4C1 pituitary cells.
Topics: Acetophenones; Animals; Benzopyrans; Calcium; Carbazoles; Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression Regulation; Indoles; Isoenzymes; Maleimides; Naphthalenes; Phorbol Esters; Pituitary Gland; Prolactin; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Staurosporine; Thyrotropin-Releasing Hormone; Transcription, Genetic | 2002 |
Effect of vascular endothelial growth factor and epidermal growth factor on iatrogenic apoptosis in human endothelial cells.
Topics: Apoptosis; Cells, Cultured; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Protective Agents; Staurosporine; Vascular Endothelial Growth Factor A | 2004 |
EGF-Like domain of tenascin-C is proapoptotic for cultured smooth muscle cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Carotid Arteries; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Cricetinae; Cysteine Proteinase Inhibitors; Dactinomycin; Dipeptides; Enzyme Activation; Enzyme Induction; Epidermal Growth Factor; Humans; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mesocricetus; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oligopeptides; Peptide Fragments; Protease Inhibitors; Protein Isoforms; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Staurosporine; Tenascin | 2004 |
Cytoprotective function of sAppalpha in human keratinocytes.
Topics: Amyloid beta-Protein Precursor; Apoptosis; Cell Adhesion; Cells, Cultured; Cytoprotection; Enzyme Activation; Epidermal Cells; Epidermal Growth Factor; Epidermis; Humans; Keratinocytes; Peptide Fragments; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Staurosporine; Sunscreening Agents; Ultraviolet Rays | 2004 |
Receptor tyrosine kinases regulate alpha1D-adrenoceptor signaling properties: phosphorylation and desensitization.
Topics: Animals; Calcium; Cell Line; Epidermal Growth Factor; Fibroblasts; Humans; Insulin; Insulin-Like Growth Factor I; Norepinephrine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Inbred F344; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, alpha-1; Signal Transduction; Staurosporine | 2009 |
Effect of inhibitors of mitogen-activated protein kinase kinase on alpha(1B)-adrenoceptor phosphorylation.
Topics: Androstadienes; Animals; Butadienes; Calcium Signaling; Cell Line; Cricetinae; Endothelin-1; Epidermal Growth Factor; Flavonoids; Genistein; Humans; Indoles; Lysophospholipids; Maleimides; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Norepinephrine; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Adrenergic, alpha-1; RNA, Small Interfering; Staurosporine; Tetradecanoylphorbol Acetate; Wortmannin | 2009 |
Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1.
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Cycloheximide; Epidermal Growth Factor; Fibroblasts; Mice; Phosphatidylinositol 3-Kinases; Phosphoric Monoester Hydrolases; Proto-Oncogene Proteins c-akt; Signal Transduction; Staurosporine | 2009 |
Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction - a model for cross-modulation.
Topics: Actins; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cytoskeleton; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium; Humans; Mesoderm; Microscopy, Confocal; Microscopy, Fluorescence; Snail Family Transcription Factors; Staurosporine; Transcription Factors; Tumor Cells, Cultured | 2009 |