staurosporine and endothelin-1

Topics: Alkaloids; Animals; Antithrombins; Arginine; Blotting, Northern; Cattle; Cells, Cultured; DNA Probes; Endothelin-1; Endothelins; Endothelium, Vascular; Gene Expression; Genes, fos; Heparin; Pipecolic Acids; Protein Kinase C; Protein Precursors; RNA, Messenger; Staurosporine; Sulfonamides; Thrombin

Topics: Affinity Labels; Animals; Aorta, Thoracic; Azides; Binding Sites; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Endothelin-1; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; Protein Kinase C; Rats; Staurosporine

Topics: Animals; Aorta; Cell Adhesion; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Endothelium, Vascular; Intercellular Adhesion Molecule-1; Myocardium; Neutrophils; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Staurosporine

Topics: Amiloride; Carrier Proteins; Cell Division; Cells, Cultured; Cerebrovascular Circulation; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Humans; Inositol 1,4,5-Trisphosphate; Microcirculation; Ouabain; Potassium; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate; Thymidine

Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bronchial Hyperreactivity; Cattle; Cyclooxygenase Inhibitors; Drug Synergism; Endothelin-1; Enzyme Inhibitors; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Muscle Contraction; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Staurosporine

Topics: Angiotensin II; Animals; Antibodies; Catheterization; Diastole; Endothelial Growth Factors; Endothelin Receptor Antagonists; Endothelin-1; Heart; In Vitro Techniques; Lymphokines; Male; Myocardial Ischemia; Myocardium; Peptides, Cyclic; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Saralasin; Staurosporine; Transcription, Genetic; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

Topics: Animals; Calcium; Cell Line; Cell Membrane; Cricetinae; Endothelin Receptor Antagonists; Endothelin-1; Fibroblasts; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Norepinephrine; Peptides, Cyclic; Phosphorylation; Rats; Receptor, Endothelin A; Receptors, Adrenergic, alpha-1; Receptors, Endothelin; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection

Topics: Actin Cytoskeleton; Actins; Animals; Aorta; Cattle; Cell Size; Cells, Cultured; Colforsin; Cytochalasin D; Cytoskeleton; Endothelin-1; Endothelium, Vascular; Gene Expression Regulation; Genistein; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic

Topics: Alkaloids; Animals; Animals, Newborn; Atrial Natriuretic Factor; Benzophenanthridines; Calcium; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Egtazic Acid; Endothelin-1; Enzyme Inhibitors; Epoprostenol; Heart; Heart Ventricles; Kinetics; Myocardium; Naphthalenes; Nifedipine; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Staurosporine; Thionucleotides

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Nifedipine; Norepinephrine; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rats; Rats, Wistar; Serotonin; Staurosporine; Streptozocin; Vasoconstriction; Vasoconstrictor Agents

Topics: Adrenergic alpha-Agonists; Animals; Autoradiography; Blotting, Western; Cells, Cultured; Down-Regulation; Endothelin-1; Enzyme Induction; Fibroblasts; Norepinephrine; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Receptors, Adrenergic, alpha-1; RNA, Messenger; Staurosporine

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Cardiotonic Agents; Cell Size; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Heart Failure; Hemodynamics; Isoproterenol; Male; Myocardial Contraction; Myocardium; Peptides, Cyclic; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Sodium-Hydrogen Exchangers; Staurosporine

Topics: Animals; Calcium; Cytoplasm; Endothelin-1; Male; Mesenteric Arteries; Norepinephrine; Osmolar Concentration; Potassium Chloride; Sodium-Potassium-Exchanging ATPase; Staurosporine; Swine; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cell Line; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; Norepinephrine; Phentolamine; Piperazines; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Staurosporine; Tetradecanoylphorbol Acetate; Transfection

Topics: Analgesics, Opioid; Animals; Anions; Arachidonic Acid; Calcium; Chelating Agents; Egtazic Acid; Endothelin-1; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gene Expression; GTP-Binding Proteins; Ion Channel Gating; Oocytes; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Rats; Receptor Cross-Talk; Receptors, Endothelin; Receptors, Muscarinic; Receptors, Opioid, mu; Staurosporine; Xenopus laevis

Topics: Actins; Adenosine Triphosphate; Animals; Blotting, Northern; Cattle; Cell Membrane; Cell Nucleus; Cells, Cultured; Collagenases; Dose-Response Relationship, Drug; Endothelin-1; Endothelium; Enzyme Inhibitors; Gene Expression Regulation; Hypoxia; Luciferases; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; RNA, Messenger; Staurosporine; Time Factors

Topics: Analysis of Variance; Animals; Anticoagulants; Antithrombin III; Calcium Channel Blockers; Drug Interactions; Endothelin-1; Enzyme Inhibitors; Genistein; Heparin; Lung; Male; Nicardipine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Staurosporine; Up-Regulation

Topics: Amiloride; Animals; Aortic Diseases; Aspartic Acid Endopeptidases; Blood Pressure; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Hypertrophy, Left Ventricular; In Vitro Techniques; Male; Metalloendopeptidases; Myocardium; Nitroglycerin; Protein Kinase C; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Endothelin; Staurosporine

Topics: Animals; Antihypertensive Agents; Blotting, Northern; Carcinogens; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation, Enzymologic; Genistein; Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; Oligopeptides; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Phorbol Esters; Phosphodiesterase Inhibitors; Phosphorylation; Piperidines; Propranolol; Protein Kinase C; Pyridines; Pyrrolidinones; RNA, Messenger; Skull; Staurosporine

Topics: Alkaloids; Animals; Benzophenanthridines; Cell Division; Cells, Cultured; DNA; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Interleukin-1; Isoenzymes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Myocardium; Phenanthridines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate

Topics: 4-Aminopyridine; Adolescent; Adult; Animals; Cells, Cultured; Charybdotoxin; Child; Endothelin-1; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Indoles; Male; Maleimides; Middle Aged; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pulmonary Artery; Staurosporine; Vasoconstriction

Topics: Animals; Blood Glucose; Body Weight; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Endothelin-1; Enzyme Inhibitors; Estrenes; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Methoxamine; Nifedipine; Perfusion; Phosphatidylinositols; Potassium Chloride; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Sodium Fluoride; Staurosporine; Streptozocin; Type C Phospholipases; Vasoconstriction; Vasoconstrictor Agents

Topics: Animals; Calcium; Endothelin-1; Enzyme Inhibitors; Gene Expression; Genes, fos; In Situ Hybridization; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Organ Culture Techniques; Phosphorylation; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptor, Endothelin A; RNA, Messenger; Signal Transduction; Staurosporine

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Azepines; Endothelin-1; Enzyme Inhibitors; Genistein; Hypoxia; Indoles; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Maleimides; Myosin-Light-Chain Kinase; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pulmonary Artery; Pyridines; Pyrimidines; Rats; Rats, Wistar; rho-Associated Kinases; src-Family Kinases; Staurosporine; Vasoconstriction

Topics: Aged; Alkaloids; Animals; Benzophenanthridines; Endothelin-1; Enzyme Inhibitors; Heart Atria; Humans; Middle Aged; Myocytes, Cardiac; Oocytes; Patch-Clamp Techniques; Potassium; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Protein Subunits; Receptor, Endothelin A; Staurosporine; Tachycardia; Xenopus laevis

Topics: Animals; Astrocytes; Cells, Cultured; Endothelin B Receptor Antagonists; Endothelin-1; Endothelins; Flavonoids; Matrix Metalloproteinase 10; Matrix Metalloproteinase 11; Matrix Metalloproteinase 3; Protein Kinase Inhibitors; Rats; RNA, Messenger; Staurosporine

Topics: Androstadienes; Animals; Butadienes; Calcium Signaling; Cell Line; Cricetinae; Endothelin-1; Epidermal Growth Factor; Flavonoids; Genistein; Humans; Indoles; Lysophospholipids; Maleimides; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Norepinephrine; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Adrenergic, alpha-1; RNA, Small Interfering; Staurosporine; Tetradecanoylphorbol Acetate; Wortmannin