staurosporine has been researched along with dinoprostone in 72 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.39) | 18.7374 |
| 1990's | 56 (77.78) | 18.2507 |
| 2000's | 13 (18.06) | 29.6817 |
| 2010's | 2 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hébert, RL; Nadler, SP; Zimpelmann, JA | 1 |
| Conquer, JA; Cruz, TF; Kandel, RA | 1 |
| Dieter, P; Duyster, J; Fitzke, E; Schulze-Specking, A | 1 |
| Kawase, T; Orikasa, M; Suzuki, A | 1 |
| Breyer, MD; Carter, CE; Jacobson, HR; Noland, TD | 1 |
| MacLeod, EA; Olson, DM; Zakar, T | 1 |
| Jiang, H; Kato, R; Yamamoto, S | 1 |
| Evans, CH; Georgescu, HI; Hulkower, KI | 1 |
| Hanna, N; Mong, S; White, JR; Zembryki, D | 1 |
| Davis, BB; Jacob, AK; Thomas, DJ; Zenser, TV | 1 |
| Decker, K; Schulze-Specking, A; Weinhold, L | 1 |
| Arner, EC; Pratta, MA | 1 |
| Tai, HH; Tian, ZG; Xun, CQ | 1 |
| Dieter, P; Fitzke, E | 1 |
| Chuang, ST; Grunstein, MM; Pawlowski, NA; Schramm, CM | 1 |
| Moore, JJ; Moore, RM; Vander Kooy, D | 1 |
| Iaizzo, PA; Olsen, RA; Powis, G; Seewald, MJ; Sehgal, I | 1 |
| Gimbrone, MA; Hrbolich, JK; Schafer, AI; Zavoico, GB | 1 |
| Fujiki, H; Hirasawa, N; Ohashi, M; Ohuchi, K; Ozeki, T; Tamura, T; Tsurufuji, S; Watanabe, M | 1 |
| Brieland, JK; Fantone, JC; McNish, RW; Peters-Golden, M | 1 |
| Breyer, MD; Hébert, RL; Jacobson, HR | 1 |
| Fertel, RH; Gabbe, SG; Iams, JD; Kniss, DA; Mershon, J; Sonek, J; Su, HC; Waxman, M | 1 |
| Insel, PA; Slivka, SR; Weiss, BA | 1 |
| Eling, TE; Hamasaki, Y | 1 |
| Cole, OF; Elder, MG; Seki, H; Sullivan, MH | 1 |
| Iitaka, M; Ishii, J; Kitahama, S | 1 |
| Benishin, CG; Ren, J | 1 |
| Dewald, B; Fey, MF; Meier, RW; Niklaus, G; Tobler, A | 1 |
| DiBattista, JA; Iwata, K; Martel-Pelletier, J; Pelletier, JP; Zafarullah, M | 1 |
| Sottile, A; Teti, D; Venza, I; Venza, M | 1 |
| Amon, U; Subramanian, N; von Stebut, E; Wolff, HH | 1 |
| Good, DW | 1 |
| Evans, CH; Georgescu, HI; Stadler, J; Stefanovic-Racic, M | 1 |
| Shibata, Y | 1 |
| Fujimura, S; Kato, N; Miya, T; Sato, K; Tagawa, M; Takahashi, K | 1 |
| Adamson, S; Coulam, C; Edwin, SS; LaMarche, S; Mitchell, MD; Silver, RM | 1 |
| Huwiler, A; Pfeilschifter, J | 1 |
| Breyer, MD; Fredin, D; Hébert, RL; Jacobson, HR | 1 |
| Hosono, T; Ito, A; Mori, Y; Nagase, H; Ojima, Y; Sato, T; Takahashi, S | 1 |
| Hirasawa, N; Mue, S; Ohuchi, K; Tamura, T; Watanabe, M | 1 |
| Mitchell, MD; Pollard, JK | 1 |
| Boneh, A; Brenner, T; Shohami, E | 1 |
| Marunouchi, T; Ohno, K; Sawada, M; Suzumura, A | 1 |
| Borzecki, JS; McKay, AJ; Peterson, LN | 1 |
| Fredholm, BB; Lerner, UH; Ljunggren, O; Ljunghall, S; Nordstedt, C | 1 |
| Breitbart, H; Marcus, S; Shalev, Y; Shemesh, M | 1 |
| Benishin, CG; Karpinski, E; Ren, J | 1 |
| Daphna-Iken, D; Morrison, AR; Rzymkiewicz, DM; Srivastava, S; Tetsuka, T | 1 |
| Gerritsen, ME; Moatter, T | 1 |
| Baylink, DJ; Baylink, TM; Fitzsimmons, RJ; Mohan, S | 1 |
| Petersen, MM; Steadman, R; Williams, JD | 1 |
| Bisogno, T; De Petrocellis, L; Di Marzo, V; Maurelli, S | 1 |
| Brennand, JE; Calder, AA; Greer, IA; Kelly, RW; Leask, R | 1 |
| Huh, SO; Kim, YH; Lee, JK; Lee, KJ; Song, DK; Suh, HW; Won, JS | 1 |
| Buc, HA; Moncion, A; Pérignon, JL | 1 |
| Fujimoto, Y; Hirata, M; Inoue, H; Iwao, T; Kajiyama, G; Kariya, K; Kawasaki, Y; Matsubara, K; Morinaka, K; Sasaki, T; Tsuchida, A; Yamamoto, S | 1 |
| Ohuchi, K; Yamaki, K; Yonezawa, T | 1 |
| Boyan, BD; Dean, DD; Schwartz, Z; Sylvia, VL | 1 |
| Boiti, C; Gobbetti, A; Guelfi, G; Zampini, D; Zerani, M | 1 |
| Asbóth, G; Barlow, DH; Bellinger, J; Bernal, AL; Ledger, W; Price, SA | 1 |
| Conquer, JA; Cruz, TF; Jones, SA | 1 |
| Iwata, N; Kataoka, Y; Masui, H; Wakabayashi, I | 1 |
| Kato, K; Kozawa, O; Matsuno, H; Niwa, M; Tokuda, H; Uematsu, T | 1 |
| Ma, ZJ; Yamaguchi, M | 1 |
| Ban, HS; Kim, YP; Lee, S; Ohuchi, K; Shin, KH; Yamaki, K | 1 |
| Akopian, AN; Flores, CM; Hargreaves, KM; Patwardhan, A; Price, TJ | 1 |
| Kim, CH; Kim, HM; Park, SY; Park, WH | 1 |
| Gangloff, SC; Grandjean-Laquerriere, A; Guenounou, M; Le Naour, R | 1 |
| Ikeda, M; Matsumoto, S; Nasu, M; Takeda, M; Tanimoto, T; Yoshida, S | 1 |
| Ceña, V; Posadas, I; Prieto-Lloret, J; Santos, P; Vellecco, V | 1 |
| Esser, J; Gabrielsson, S; Gehrmann, U; Haeggström, JZ; Rådmark, O; Salvado, MD; Samuelsson, B; Scheynius, A; Wetterholm, A | 1 |
| Chen, X; Fan, Y; Guo, N; Han, J; Yang, B; Zhang, L | 1 |
72 other study(ies) available for staurosporine and dinoprostone
| Article | Year |
|---|---|
PGE2 inhibits water permeability at a post-cAMP site in rat terminal inner medullary collecting duct.
Topics: Alkaloids; Animals; Calcium; Cyclic AMP; Dinoprostone; Intracellular Membranes; Kidney Medulla; Kidney Tubules, Collecting; Male; Permeability; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Vasopressins; Water | 1992 |
Interleukin 1 and phorbol 12-myristate 13-acetate induce collagenase and PGE2 production through a PKC-independent mechanism in chondrocytes.
Topics: Alkaloids; Animals; Arachidonic Acid; Cartilage, Articular; Cattle; Cell Compartmentation; Cells, Cultured; Dinoprostone; Enzyme Induction; Interleukin-1; Microbial Collagenase; Phospholipases A; Phospholipases A2; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Protein kinase C involved in zymosan-induced release of arachidonic acid and superoxide but not in calcium ionophore-elicited arachidonic acid release or formation of prostaglandin E2 from added arachidonate.
Topics: Alkaloids; Animals; Arachidonic Acids; Blotting, Western; Calcimycin; Carbazoles; Cells, Cultured; Dinoprostone; Indole Alkaloids; Kupffer Cells; Male; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Phorbol ester-like action of staurosporine on the cAMP response to prostaglandin E2 in two macrophage-like cell lines at distinct differentiation stages.
Topics: Alkaloids; Animals; Cell Differentiation; Cell Line; Culture Media; Cyclic AMP; Dinoprostone; Macrophages; Mice; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
PGE2 regulates cAMP production in cultured rabbit CCD cells: evidence for dual inhibitory mechanisms.
Topics: Alkaloids; Animals; Arginine Vasopressin; Cells, Cultured; Cyclic AMP; Dinoprostone; Kidney Cortex; Kidney Tubules, Collecting; Pertussis Toxin; Prostaglandins; Protein Kinase C; Rabbits; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1992 |
Glucocorticoid stimulation of amnion cell prostaglandin synthesis: suppression by protein kinase C inhibitors and independence of phorbol ester-sensitive protein kinase C.
Topics: Alkaloids; Amnion; Cells, Cultured; Dexamethasone; Dinoprostone; Humans; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Staurosporine, a potent protein kinase C inhibitor, augments phorbol ester-caused ornithine decarboxylase induction in mouse epidermis.
Topics: Administration, Topical; Alkaloids; Animals; Dinoprostone; Drug Synergism; Enzyme Induction; Epidermis; Female; Indomethacin; Mice; Ornithine Decarboxylase; Protein Kinase C; Skin; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Evidence that responses of articular chondrocytes to interleukin-1 and basic fibroblast growth factor are not mediated by protein kinase C.
Topics: Alkaloids; Animals; Cartilage, Articular; Cells, Cultured; Dinoprostone; Enzyme Activation; Fibroblast Growth Factor 2; Gelatinases; Interleukin-1; Isoenzymes; Kinetics; Pepsin A; Phosphoproteins; Phosphorylation; Protein Kinase C; Rabbits; Recombinant Proteins; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Differential inhibition of histamine release from mast cells by protein kinase C inhibitors: staurosporine and K-252a.
Topics: Alkaloids; Animals; Antibodies, Anti-Idiotypic; Carbazoles; Dinoprostone; Enzyme Activation; Histamine Release; Immunoglobulin E; Indole Alkaloids; Male; Mast Cells; Mice; Mice, Inbred CBA; Molecular Weight; p-Methoxy-N-methylphenethylamine; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Rats, Inbred Strains; SRS-A; Staurosporine | 1990 |
Regulation of prostaglandin H synthase activity in dog urothelial cells.
Topics: Alkaloids; Animals; Arachidonic Acid; Aspirin; Cells, Cultured; Cycloheximide; Dinoprostone; Dogs; Prostaglandin-Endoperoxide Synthases; Staurosporine; Tetradecanoylphorbol Acetate; Urinary Bladder | 1992 |
Signal transduction in endotoxin-stimulated synthesis of TNF-alpha and prostaglandin E2 by rat Kupffer cells. Role of extracellular calcium ions and protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Cells, Cultured; Dinoprostone; Egtazic Acid; Endotoxins; Interferon-gamma; Isoquinolines; Kinetics; Kupffer Cells; Lipopolysaccharides; Male; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Recombinant Proteins; Salmonella; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1991 |
Modulation of interleukin-1-induced alterations in cartilage proteoglycan metabolism by activation of protein kinase C.
Topics: Alkaloids; Animals; Carcinogens; Cartilage; Cattle; Dinoprostone; Diterpenes; Down-Regulation; Enzyme Activation; Interleukin-1; Organ Culture Techniques; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Proteoglycans; Staurosporine; Terpenes | 1991 |
Stimulation of synthesis de novo of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase in human promyelocytic leukaemia (HL-60) cells by phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Western; Dimethyl Sulfoxide; Dinoprostone; Enzyme Activation; Enzyme Induction; Humans; Hydroxyprostaglandin Dehydrogenases; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; NAD; Piperazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
RO 31-8220 and RO 31-7549 show improved selectivity for protein kinase C over staurosporine in macrophages.
Topics: Alkaloids; Animals; Cells, Cultured; Dinoprostone; Indoles; Kinetics; Macrophages; Maleimides; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Role of endothelin 1 in regulating rabbit airway contractility.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Dinoprostone; Endothelins; Epithelium; Epoprostenol; In Vitro Techniques; Indomethacin; Isometric Contraction; Isoquinolines; Kinetics; Muscle, Smooth; Piperazines; Protein Kinase Inhibitors; Rabbits; Reference Values; Staurosporine; Sulfonamides; Trachea | 1991 |
Protein kinase-C activation is required for oxytocin-induced prostaglandin production in human amnion cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Isoquinolines; Oxytocin; Phorbol Esters; Piperazines; Pregnancy; Protein Kinase C; RNA, Messenger; Staurosporine; Time Factors; Type C Phospholipases | 1991 |
Platelet-derived growth factor stimulates non-mitochondrial Ca2+ uptake and inhibits mitogen-induced Ca2+ signaling in Swiss 3T3 fibroblasts.
Topics: Alkaloids; Animals; Biological Transport, Active; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Dinoprostone; Fibroblasts; Ionomycin; Kinetics; Mice; Mitogens; Phospholipid Ethers; Platelet-Derived Growth Factor; Protein Kinase C; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1990 |
Enhancement of thrombin- and ionomycin-stimulated prostacyclin and platelet-activating factor production in cultured endothelial cells by a tumor-promoting phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Arachidonic Acids; Calcimycin; Cells, Cultured; Dinoprost; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Ionomycin; Isoquinolines; Phorbol Esters; Phospholipases A; Phospholipases A2; Piperazines; Platelet Activating Factor; Prostaglandin D2; Prostaglandins H; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Dual effects of staurosporine on arachidonic acid metabolism in rat peritoneal macrophages.
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carcinogens; Cycloheximide; Dinoprostone; Dose-Response Relationship, Drug; Kinetics; Macrophages; Peritoneal Cavity; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Diminished protein kinase C-activated arachidonate metabolism accompanies rat macrophage differentiation in the lung.
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Differentiation; Dinoprostone; Eicosanoids; Enzyme Activation; Female; Macrophages; Peritoneal Cavity; Phorbol Esters; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Sphingosine; Staurosporine; Superoxides; Zymosan | 1990 |
PGE2 inhibits AVP-induced water flow in cortical collecting ducts by protein kinase C activation.
Topics: Alkaloids; Animals; Arginine Vasopressin; Calcium; Cyclic AMP; Dinoprostone; Enzyme Activation; In Vitro Techniques; Kidney Tubules; Kidney Tubules, Collecting; Osmolar Concentration; Osmosis; Protein Kinase C; Rabbits; Staurosporine; Thionucleotides; Water | 1990 |
Evidence of a role for protein kinase C in epidermal growth factor-induced prostaglandin E2 synthesis in amnion cells.
Topics: Alkaloids; Amnion; Cell Line; Dinoprostone; Down-Regulation; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Pregnancy; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Defining the role of protein kinase C in epinephrine- and bradykinin-stimulated arachidonic acid metabolism in Madin-Darby canine kidney cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Cell Line; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Epinephrine; Isoquinolines; Kidney; Piperazines; Protein Kinase C; Receptors, Adrenergic, alpha; Receptors, Bradykinin; Receptors, Neurotransmitter; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
EGF and TPA stimulate de novo synthesis of PGHS-1 and PGHS-2 through different signal transduction pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Line, Transformed; Cinnamates; Dinoprostone; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium; Isoquinolines; Piperazines; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Trachea | 1995 |
Interleukin-1 beta-stimulated prostaglandin synthesis by human decidual cells is independent of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Decidua; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Interleukin-1; Isoquinolines; Piperazines; Pregnancy; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Involvement of protein kinase A and C in the production of interleukin-1 alpha-induced prostaglandin E2 from mouse osteoblast-like cell line, MC3T3-E1.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dinoprostone; Humans; Indoles; Indomethacin; Interleukin-1; Isoquinolines; Kinetics; Mice; Osteoblasts; Piperazines; Protein Kinase C; Pyrroles; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Evidence that prostaglandin E2 can block calcium-activated 86Rb efflux from rat brain synaptosomes via a protein kinase C-dependent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Calcium Channel Blockers; Charybdotoxin; Cyclic AMP; Dinoprostone; Isoquinolines; Kinetics; Male; Phorbol 12,13-Dibutyrate; Piperazines; Prosencephalon; Protein Kinase C; Rats; Rats, Sprague-Dawley; Rubidium; Scorpion Venoms; Staurosporine; Sulfonamides; Synaptosomes; Thionucleotides | 1994 |
Inhibition of the arachidonic acid pathway prevents induction of IL-8 mRNA by phorbol ester and changes the release of IL-8 from HL 60 cells: differential inhibition of induced expression of IL-8, TNF-alpha, IL-1 alpha, and IL-1 beta.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Alkaloids; Arachidonic Acid; Cycloheximide; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Gene Expression; HL-60 Cells; Humans; In Vitro Techniques; Inflammation Mediators; Interleukin-1; Interleukin-8; Leukotriene B4; Lipoxygenase Inhibitors; Phospholipases A; Protein Kinase C; Protein Synthesis Inhibitors; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
Interleukin-1 beta induction of tissue inhibitor of metalloproteinase (TIMP-1) is functionally antagonized by prostaglandin E2 in human synovial fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Northern; Bucladesine; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Glycoproteins; Humans; Immunoenzyme Techniques; Interleukin-1; Isoquinolines; Metalloendopeptidases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Recombinant Proteins; RNA, Messenger; Staurosporine; Synovial Membrane; Tetradecanoylphorbol Acetate; Thionucleotides; Tissue Inhibitor of Metalloproteinases; Up-Regulation | 1995 |
Prostaglandins affect the respiratory burst of human neutrophils.
Topics: Alkaloids; Cells, Cultured; Dinoprostone; Humans; Neutrophils; Prostaglandins; Protein Kinase C; Respiratory Burst; Staurosporine; Superoxides | 1995 |
CGP 41251, a novel protein kinase inhibitor with in vitro selectivity for protein kinase C, strongly inhibits immunological activation of human skin mast cells and human basophils.
Topics: Alkaloids; Basophils; Dinoprostone; Female; Histamine Release; Humans; Leukotrienes; Mast Cells; Protein Kinase C; Receptors, IgE; Signal Transduction; Skin; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Hyperosmolality inhibits bicarbonate absorption in rat medullary thick ascending limb via a protein-tyrosine kinase-dependent pathway.
Topics: Absorption; Alkaloids; Animals; Arginine Vasopressin; Benzoquinones; Bicarbonates; Colforsin; Dinoprostone; Drug Interactions; Genistein; Isoflavones; Kidney Medulla; Lactams, Macrocyclic; Loop of Henle; Mannitol; Molybdenum; Osmolar Concentration; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Sodium Chloride; Staurosporine | 1995 |
Nitric oxide synthesis and its regulation by rabbit synoviocytes.
Topics: Alkaloids; Animals; Cell Line; Cells, Cultured; Cytokines; Dinoprostone; Fibroblasts; Free Radicals; Interferon-gamma; Interleukin-1; Metalloendopeptidases; Nitric Oxide; Platelet-Derived Growth Factor; Protein Kinase C; Rabbits; Staurosporine; Synovial Membrane; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1994 |
Prostaglandin E2 release triggered by phagocytosis of latex particles. A distinct association with prostaglandin synthase isozymes in bone marrow macrophages.
Topics: Alkaloids; Animals; Bone Marrow; Bone Marrow Cells; Cytochalasin D; Dinoprostone; Female; Flow Cytometry; Interferon-gamma; Interleukin-3; Isoenzymes; Latex; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Microspheres; Phagocytosis; Prostaglandin-Endoperoxide Synthases; Staurosporine | 1995 |
Prostaglandin E2/parathyroid hormone-induced suppression of alkaline phosphatase activity is mediated by protein kinase C.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Bucladesine; Calcimycin; Cyclic AMP; Cycloheximide; Dinoprostone; Isoquinolines; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Regulation of intrauterine prostaglandin biosynthesis: interactions between protein kinase C and interleukin 1 beta.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Chorion; Decidua; Dinoprostone; Female; Humans; In Vitro Techniques; Interleukin-1; Isoquinolines; Obstetric Labor, Premature; Piperazines; Pregnancy; Protein Kinase C; Staurosporine; Uterus | 1994 |
A role for protein kinase C-alpha in zymosan-stimulated eicosanoid synthesis in mouse peritoneal macrophages.
Topics: Alkaloids; Animals; Arachidonic Acid; Cells, Cultured; Dinoprostone; Eicosanoids; Fatty Acids; Isoenzymes; Kinetics; Leukotriene C4; Macrophages, Peritoneal; Mice; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Evidence that separate PGE2 receptors modulate water and sodium transport in rabbit cortical collecting duct.
Topics: Alkaloids; Analysis of Variance; Animals; Arginine Vasopressin; Body Water; Calcium; Dinoprostone; Egtazic Acid; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Perfusion; Pertussis Toxin; Protein Kinase C; Rabbits; Receptors, Prostaglandin E; Sodium; Staurosporine; Time Factors; Virulence Factors, Bordetella | 1993 |
Involvement of protein kinase C in the interleukin 1 alpha-induced gene expression of matrix metalloproteinases and tissue inhibitor-1 of metalloproteinases (TIMP-1) in human uterine cervical fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cells, Cultured; Collagen; Dinoprostone; Down-Regulation; Extracellular Matrix; Female; Fibroblasts; Gene Expression Regulation; Glycoproteins; Guinea Pigs; Humans; Interleukin-1; Isoquinolines; Metalloendopeptidases; Piperazines; Protein Kinase C; Protein Precursors; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Uterus | 1993 |
Stimulation of prostaglandin E2 production and induction of specific protein synthesis in rat peritoneal macrophages by a tumor promoter staurosporine.
Topics: Alkaloids; Animals; Arachidonic Acid; Carcinogens; Cells, Cultured; Dinoprostone; Macrophages, Peritoneal; Male; Methionine; Protein Biosynthesis; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Time Factors | 1993 |
Tumor necrosis factor alpha stimulates amnion prostaglandin biosynthesis primarily via an action on fatty acid cyclooxygenase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Arachidonic Acid; Aspirin; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Female; Humans; Isoquinolines; Piperazines; Pregnancy; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Differential effects of phorbol myristate acetate and dexamethasone on protein kinase C activity and eicosanoids production in cultured rat astrocytes.
Topics: Alkaloids; Animals; Astrocytes; Biomarkers; Cells, Cultured; Colforsin; Dexamethasone; Dinoprostone; Eicosanoids; Female; Fluorescent Antibody Technique; Neuroglia; Pregnancy; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Regulation of astrocyte proliferation by prostaglandin E2 and the alpha subtype of protein kinase C.
Topics: Alkaloids; Animals; Astrocytes; Cell Division; Cells, Cultured; Dinoprostone; Enzyme Activation; Indomethacin; Lipopolysaccharides; Mice; Mice, Inbred ICR; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Endogenous prostaglandin E2 mediates inhibition of rat thick ascending limb Cl reabsorption in chronic hypercalcemia.
Topics: Alkaloids; Animals; Biological Transport, Active; Chlorides; Chronic Disease; Colforsin; Cyclic AMP; Dihydrotachysterol; Dinoprostone; Furosemide; Hypercalcemia; In Vitro Techniques; Indomethacin; Kidney Medulla; Kidney Tubules, Collecting; Male; Perfusion; Rats; Rats, Sprague-Dawley; Staurosporine | 1993 |
Role of protein kinase C in bradykinin-induced prostaglandin formation in osteoblasts.
Topics: Alkaloids; Animals; Bradykinin; Calcimycin; Cell Membrane; Cells, Cultured; Dinoprostone; Enzyme Activation; Hydrocortisone; Indomethacin; Mice; Osteoblasts; Phorbol 12,13-Dibutyrate; Prostaglandins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Modulation of prostaglandin synthesis in mammalian sperm acrosome reaction.
Topics: Acrosome; Alkaloids; Animals; Arachidonic Acid; Calcimycin; Cattle; Dinoprost; Dinoprostone; Enzyme Inhibitors; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Prostaglandin-Endoperoxide Synthases; Spermatozoa; Staurosporine | 1995 |
The actions of prostaglandin E2 on potassium currents in rat tail artery vascular smooth muscle cells: regulation by protein kinase A and protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Male; Muscle, Smooth, Vascular; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Tail; Tetradecanoylphorbol Acetate | 1996 |
Interleukin-1beta activates protein kinase C zeta in renal mesangial cells. Potential role in prostaglandin E2 up-regulation.
Topics: Alkaloids; Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Cytosol; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Interleukin-1; Kinetics; Male; Molecular Sequence Data; Naphthalenes; NF-kappa B; Oligonucleotide Probes; Oligonucleotides, Antisense; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Restriction Mapping; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1996 |
Acidic fibroblast factor induction of cyclooxygenase II in rabbit cardiac muscle microvessel endothelial cells: mediation by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Arachidonic Acid; Blotting, Northern; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Fibroblast Growth Factor 1; Inositol Phosphates; Isoenzymes; Isoquinolines; Microcirculation; Myocardium; Naphthalenes; Piperazines; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rabbits; RNA, Messenger; Staurosporine; Sulfonamides | 1994 |
Evaluation of signal transduction mechanisms for the mitogenic effects of prostaglandin E2 in normal human bone cells in vitro.
Topics: Analysis of Variance; Anti-Bacterial Agents; Bone and Bones; Bone Development; Calcium; Calcium Channels; Cell Count; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Isotope Labeling; Mitogens; Protein Kinase C; Pyrimidine Nucleosides; Signal Transduction; Staurosporine; Thymidine | 1996 |
Human neutrophil secondary granule exocytosis is independent of protein kinase activation and is modified by calmodulin activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Bucladesine; Calmodulin; Cytoplasmic Granules; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Genistein; Humans; Isoflavones; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vanadates | 1996 |
The endogenous cannabimimetic eicosanoid, anandamide, induces arachidonate release in J774 mouse macrophages.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amides; Animals; Arachidonic Acid; Arachidonic Acids; Cyclic AMP; Dinoprostone; Endocannabinoids; Enzyme Activation; Ethanolamines; Genistein; GTP-Binding Proteins; Linoleic Acids; Macrophages; Mice; Naphthalenes; Neuroblastoma; Nitriles; Palmitic Acids; Phospholipases A; Polyunsaturated Alkamides; Second Messenger Systems; Staurosporine; Tumor Cells, Cultured; Tyrphostins; Virulence Factors, Bordetella | 1997 |
Mechanisms involved in the stimulatory effect of amniotic fluid on prostaglandin production by human fetal membranes.
Topics: Amniotic Fluid; Cells, Cultured; Cesarean Section; Chorion; Cycloheximide; Dactinomycin; Dinoprost; Dinoprostone; Enzyme Inhibitors; Extraembryonic Membranes; Female; Genistein; Humans; Labor, Obstetric; Pregnancy; Prostaglandins; Staurosporine | 1998 |
Prostaglandin E2 increases proenkephalin mRNA level in rat astrocyte-enriched culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Dinoprostone; Enkephalins; Enzyme Inhibitors; Flavonoids; Imidazoles; Isoquinolines; Kinetics; Nimodipine; omega-Conotoxin GVIA; Peptides; Phosphorylation; Protein Precursors; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Sulfonamides; Transcription Factor AP-1; Transcription, Genetic | 1998 |
Regulation of adenylyl cyclase activity in human peripheral blood mononuclear cells: effects of protein kinase inhibitors and of a calcium ionophore.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adult; Calcimycin; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Humans; Ionophores; Leukocytes, Mononuclear; Staurosporine | 1998 |
Cholecystokinin regulates the invasiveness of human pancreatic cancer cell lines via protein kinase C pathway.
Topics: Blotting, Western; Cholecystokinin; Collagenases; Cyclooxygenase Inhibitors; Dinoprostone; Dopamine Agents; Enzyme Induction; Enzyme Inhibitors; Humans; Immunoenzyme Techniques; Indomethacin; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Pancreatic Neoplasms; Protein Kinase C; Signal Transduction; Sincalide; Staurosporine; Tumor Cells, Cultured | 1999 |
Signal transduction cascade in staurosporine-induced prostaglandin E(2) production by rat peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Blotting, Western; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Isoenzymes; Kinetics; Macrophages, Peritoneal; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine | 2000 |
Transforming growth factor-beta1 regulation of resting zone chondrocytes is mediated by two separate but interacting pathways.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Arachidonic Acid; Benzophenanthridines; Cell Division; Cell Membrane; Chondrocytes; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Male; Phenanthridines; Phospholipases A; Protein Kinase C; Proteoglycans; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Transforming Growth Factor beta | 2000 |
Prostaglandin receptors and role of G protein-activated pathways on corpora lutea of pseudopregnant rabbit in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Analysis of Variance; Animals; Colforsin; Corpus Luteum; Culture Techniques; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Imipramine; Luteal Phase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Progesterone; Protein Kinase C; Pseudopregnancy; Rabbits; Receptors, Prostaglandin; Receptors, Prostaglandin E; Signal Transduction; Statistics, Nonparametric; Staurosporine; Type C Phospholipases | 2001 |
Characterization of adenylyl cyclases in cultured human granulosa cells.
Topics: Adenylyl Cyclases; Calcimycin; Calcium; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Female; Granulosa Cells; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Isoenzymes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 2001 |
Effect of interleukin 1, lipopolysaccharide and phorbol esters on phospholipase D activity in chondrocytes.
Topics: Animals; Cattle; Chondrocytes; Dinoprostone; Down-Regulation; Interleukin-1; Lipopolysaccharides; Phospholipase D; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Acidosis inhibits gallbladder contraction mediated by protein kinase C activation.
Topics: Acidosis; Animals; Calcium; Calcium Chloride; Dinoprostone; Enzyme Activation; Extracellular Space; Gallbladder; Guinea Pigs; HEPES; Histamine; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle Contraction; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Staurosporine | 2001 |
Mechanism of prostaglandin E2-stimulated heat shock protein 27 induction in osteoblast-like MC3T3-E1 cells.
Topics: Analysis of Variance; Animals; Butadienes; Calcium; Calcium Channel Blockers; Cell Line; Chelating Agents; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Gallic Acid; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Molecular Chaperones; Naphthalenes; Neoplasm Proteins; Nitriles; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Pyrrolidinones; Staurosporine; Stimulation, Chemical; Time Factors; Type C Phospholipases | 2002 |
Inhibitory effect of menaquinone-7 (vitamin K2) on osteoclast-like cell formation and osteoclastic bone resorption in rat bone tissues in vitro.
Topics: Animals; Bone and Bones; Bone Marrow Cells; Bone Resorption; Bucladesine; Calcitonin; Calcium; Carcinogens; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Hemostatics; Male; Osteoclasts; Oxytocics; Peptide Fragments; Rats; Rats, Wistar; Staurosporine; Teriparatide; Tetradecanoylphorbol Acetate; Vitamin K 2 | 2001 |
Inhibition of prostaglandin E(2) production by taiwanin C isolated from the root of Acanthopanax chiisanensis and the mechanism of action.
Topics: Animals; Arachidonic Acid; Araliaceae; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Drug Interactions; Enzyme Inhibitors; Isoenzymes; Lactones; Lignans; Macrophages, Peritoneal; Male; Membrane Proteins; Plant Roots; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Tritium | 2002 |
Modulation of trigeminal sensory neuron activity by the dual cannabinoid-vanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide.
Topics: Aminobutyrates; Animals; Arachidonic Acid; Arachidonic Acids; Calcitonin Gene-Related Peptide; Calcium Channels; Capsaicin; Dinoprostone; Diterpenes; Dopamine; Endocannabinoids; Ganglia, Spinal; Male; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Drug; Staurosporine; Trigeminal Ganglion; TRPC Cation Channels; TRPV Cation Channels | 2004 |
Effect of a Korean traditional formulation, Hwaotang, on superoxide generation in human neutrophils, platelet aggregation in human blood, and nitric oxide, prostaglandin E2 production and paw oedema induced by carrageenan in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Carrageenan; Cell Degranulation; Cyclooxygenase 1; Cyclooxygenase 2; Cytochalasin B; Dinoprostone; Edema; Female; Gastric Mucosa; Gene Expression; Genistein; Hindlimb; Humans; Indomethacin; Isoenzymes; Korea; Leukotriene B4; Lipopolysaccharides; Macrophages, Peritoneal; Medicine, East Asian Traditional; Membrane Proteins; Mice; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pancreatic Elastase; Phosphoproteins; Phosphorylation; Phosphotyrosine; Plant Extracts; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Staurosporine; Stomach; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 2004 |
Contribution of protein kinase A and protein kinase C pathways in ultraviolet B-induced IL-8 expression by human keratinocytes.
Topics: Cell Line; Cholera Toxin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Gene Expression Regulation; Humans; Interleukin-8; Keratinocytes; NF-kappa B; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Staurosporine; Ultraviolet Rays | 2005 |
Prostaglandin E2-induced modification of tetrodotoxin-resistant Na+ currents involves activation of both EP2 and EP4 receptors in neonatal rat nodose ganglion neurones.
Topics: Alprostadil; Animals; Animals, Newborn; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorides; Gene Expression; Immunohistochemistry; Membrane Potentials; Methyl Ethers; Neurons; Nodose Ganglion; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channels; Staurosporine; Tetrodotoxin; Time Factors | 2005 |
Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line.
Topics: Acetaminophen; Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochromes c; Dinoprostone; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Free Radical Scavengers; Glutathione; Humans; Metalloporphyrins; Neuroblastoma; Prostaglandin-Endoperoxide Synthases; Staurosporine; Time Factors | 2007 |
Zymosan suppresses leukotriene C₄ synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors.
Topics: Aspirin; Cell Differentiation; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Glutathione Transferase; Humans; Leukotriene C4; Macrophages; Protein Kinase C; Protein Kinase Inhibitors; Receptors, Prostaglandin E; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Staurosporine; Toll-Like Receptor 2; Zymosan | 2011 |
Effects of all-trans retinoic acid on signal pathway of cyclooxygenase-2 and Smad3 in transforming growth factor-β-stimulated glomerular mesangial cells.
Topics: Animals; Apoptosis; Cell Line; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Fibrosis; Glomerular Mesangium; Mesangial Cells; Nitrobenzenes; Protein Transport; Rats; RNA, Messenger; Signal Transduction; Smad3 Protein; Smad7 Protein; Staurosporine; Sulfonamides; Thromboxane A2; Transforming Growth Factor beta; Tretinoin | 2014 |