Compounds > staurosporine
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staurosporine and dasatinib

staurosporine has been researched along with dasatinib in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (32.14)29.6817
2010's18 (64.29)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Antczak, C; Beresten-Kochetkov, T; Clarkson, B; Djaballah, H; Lambek, C; Larson, SM; Namavari, M; Pillarsetty, N; Punzalan, BJ; Santos, EB; Smith-Jones, PM; Veach, DR1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Gallant, P; Herrgard, S; Hunt, JP; Karaman, MW; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Treiber, DK; Wodicka, LM; Zarrinkar, PP1
Getlik, M; Grütter, C; Klüter, S; Rabiller, M; Rauh, D; Rode, HB; Simard, JR1
Russu, WA; Shallal, HM1
Andreani, A; Granaiola, M; Kondapaka, S; Lannigan, D; Leoni, A; Locatelli, A; Morigi, R; Rambaldi, M; Scudiero, D; Shoemaker, RH; Smith, J; Varoli, L1
Ciceri, P; Davis, MI; Herrgard, S; Hocker, M; Hunt, JP; Pallares, G; Treiber, DK; Wodicka, LM; Zarrinkar, PP1
Al-Mazaideh, GM; Erdmann, F; Göllner, C; Rohe, A; Schmidt, M; Sippl, W; Wichapong, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, Y; Gao, L; Li, J; Lu, W; Shen, Q; Tong, L; Zhang, Q1
Aydogan, Y; Berger, BT; Chaikuad, A; Drewry, DH; Knapp, S; Mandel, S; Mauer, S; Müller, S; Pohl, C; Russ, N; Schröder, M1
von Mehren, M1
Aichberger, KJ; Baumgartner, C; Fabbro, D; Gleixner, KV; Gruze, A; Lee, FY; Manley, PW; Mayerhofer, M; Pickl, WF; Samorapoompichit, P; Sillaber, C; Sonneck, K; Valent, P1
Clement, M; Dix, C; Einsele, H; Fenton-May, A; Gostick, E; Greiner, E; Price, DA; Seggewiss, R; Sewell, AK; Weichsel, R; Wooldridge, L; Zezula, J1
Tallman, M1
Baumgartner, C; Gleixner, KV; Gruze, A; Hadzijusufovic, E; Peter, B; Pickl, WF; Rebuzzi, L; Thaiwong, T; Valent, P; Willmann, M; Yuzbasiyan-Gurkan, V1
Ashman, LK; Griffith, R; Mashkani, B1
Gleixner, KV; Hadzijusufovic, E; Mirkina, I; Peter, B; Pickl, WF; Schuch, K; Thaiwong, T; Valent, P; Willmann, M; Yuzbasiyan-Gurkan, V1
Pardanani, A1
Akin, C; DeRemer, DL; Ustun, C1
Andrich, K; Dalhoff, C; Dreger, M; Fischer, JJ; Glinski, M; Graebner, OY; Koester, H; Kroll, F; Michaelis, S; Schrey, AK; Sefkow, M1
Bennett, KL; Cerny-Reiterer, S; Gleixner, KV; Gotlib, J; Hadzijusufovic, E; Hörmann, G; Horny, HP; Mayerhofer, M; Meyer, RA; Mitterbauer-Hohendanner, G; Pickl, WF; Reiter, A; Rix, U; Superti-Furga, G; Valent, P1
Akita, K; Fujii, I; Gouda, M; Ishihama, Y; Kirii, Y; Kitagawa, D; Narumi, Y; Sugiyama, N; Yokota, K1
Bronson, R; Christie, AL; Daley, JF; Galinsky, I; Gray, N; Griffin, JD; Hur, W; Kung, AL; Liu, Q; Mitsiades, C; Nelson, E; Sanda, T; Sattler, M; Smith, R; Stone, R; Weisberg, E; Zhao, Z1
Barra, FF; Costa, FF; de Melo Campos, P; Duarte, AS; Lorand-Metze, I; Machado-Neto, JA; Olalla Saad, ST; Rogers, HJ; Scopim-Ribeiro, R; Tabarroki, A; Tiu, RV; Traina, F; Vassalo, J; Visconte, V1
Arock, M; Berger, D; Bibi, S; Blatt, K; Eisenwort, G; Hadzijusufovic, E; Herrmann, H; Hoermann, G; Hoffmann, T; Horny, HP; Jawhar, M; Moriggl, R; Peter, B; Reiter, A; Schwaab, J; Sotlar, K; Sperr, WR; Stefanzl, G; Valent, P; Willmann, M; Wingelhofer, B; Zuber, J1
Dixit, SM; Kulju, KD; Polasky, DA; Ruotolo, BT; Vallejo, DD1
Anders, S; Bach, K; Bantscheff, M; Childs, D; Franken, H; Huber, W; Kurzawa, N; Savitski, MM1

Reviews

2 review(s) available for staurosporine and dasatinib

ArticleYear
Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors.
    Clinical colorectal cancer, 2006, Volume: 6 Suppl 1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Bevacizumab; Clinical Trials as Topic; Dasatinib; Drug Resistance, Neoplasm; Everolimus; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunosuppressive Agents; Indoles; Niacinamide; Oligonucleotides; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sirolimus; Staurosporine; Sunitinib; Thiazoles

2006
Tyrosine kinase inhibitors in the treatment of systemic mastocytosis.
    Leukemia research, 2011, Volume: 35, Issue:9

    Topics: Animals; Benzamides; Dasatinib; Humans; Imatinib Mesylate; Mastocytosis, Systemic; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Staurosporine; Thiazoles

2011

Other Studies

26 other study(ies) available for staurosporine and dasatinib

ArticleYear
Synthesis and biological evaluation of a fluorine-18 derivative of dasatinib.
    Journal of medicinal chemistry, 2007, Nov-15, Volume: 50, Issue:23

    Topics: Animals; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Dasatinib; Fluorine Radioisotopes; Fusion Proteins, bcr-abl; Humans; Mice; Mice, Nude; Positron-Emission Tomography; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Radiopharmaceuticals; src-Family Kinases; Thiazoles; Transplantation, Heterologous

2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
A quantitative analysis of kinase inhibitor selectivity.
    Nature biotechnology, 2008, Volume: 26, Issue:1

    Topics: Binding Sites; Enzyme Activation; Humans; Phosphotransferases; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Proteome; Quantitative Structure-Activity Relationship

2008
A new screening assay for allosteric inhibitors of cSrc.
    Nature chemical biology, 2009, Volume: 5, Issue:6

    Topics: Adenosine Triphosphate; Allosteric Regulation; Binding Sites; Crystallography, X-Ray; Hydrogen Bonding; Proto-Oncogene Proteins pp60(c-src)

2009
Discovery, synthesis, and investigation of the antitumor activity of novel piperazinylpyrimidine derivatives.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Pyrimidines; Stereoisomerism; Structure-Activity Relationship

2011
Imidazo[2,1-b]thiazole guanylhydrazones as RSK2 inhibitors.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Hydrazones; Magnetic Resonance Spectroscopy; Ribosomal Protein S6 Kinases; Spectrophotometry, Infrared

2011
Comprehensive analysis of kinase inhibitor selectivity.
    Nature biotechnology, 2011, Oct-30, Volume: 29, Issue:11

    Topics: Catalysis; Drug Design; Enzyme Stability; High-Throughput Screening Assays; Humans; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Proteomics; Signal Transduction; Substrate Specificity

2011
Evaluation of potential Myt1 kinase inhibitors by TR-FRET based binding assay.
    European journal of medicinal chemistry, 2013, Volume: 61

    Topics: Dose-Response Relationship, Drug; Fluorescence Resonance Energy Transfer; Glycolipids; Humans; Membrane Proteins; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Structure-Activity Relationship

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Animals; Antineoplastic Agents; Aurora Kinase A; Aurora Kinase B; Azepines; Cell Line, Tumor; Humans; Mice; Mice, Nude; Neoplasms; Protein Kinase Inhibitors; Pyrazoles; Vascular Endothelial Growth Factor Receptor-2

2018
Design and Development of a Chemical Probe for Pseudokinase Ca
    Journal of medicinal chemistry, 2021, 10-14, Volume: 64, Issue:19

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Drug Design; Humans; Molecular Probes; Protein Kinase Inhibitors; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine

2021
Synergistic growth-inhibitory effects of two tyrosine kinase inhibitors, dasatinib and PKC412, on neoplastic mast cells expressing the D816V-mutated oncogenic variant of KIT.
    Haematologica, 2007, Volume: 92, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Survival; Dasatinib; Drug Synergism; Humans; Mast Cells; Mastocytosis, Systemic; Mutation, Missense; Neoplasm Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Staurosporine; Thiazoles

2007
Profound inhibition of antigen-specific T-cell effector functions by dasatinib.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Apr-15, Volume: 14, Issue:8

    Topics: Apoptosis; Cells, Cultured; Dasatinib; Dose-Response Relationship, Drug; Humans; Immunologic Memory; Interleukin-2; Lymphocyte Activation; Protein Kinase Inhibitors; Pyrimidines; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Staurosporine; T-Lymphocytes; Thiazoles

2008
Existing and emerging therapeutic options for the treatment of acute myeloid leukemia.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Adenine; Adenine Nucleotides; Aminoglycosides; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arabinonucleosides; Carbazoles; Clofarabine; Cytarabine; Dasatinib; Daunorubicin; fms-Like Tyrosine Kinase 3; Furans; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Naphthalimides; Organophosphonates; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Sesquiterpenes; Staurosporine; Stem Cell Transplantation; Thiazoles; Tretinoin

2008
Growth-inhibitory effects of four tyrosine kinase inhibitors on neoplastic feline mast cells exhibiting a Kit exon 8 ITD mutation.
    Veterinary immunology and immunopathology, 2009, Dec-15, Volume: 132, Issue:2-4

    Topics: Animals; Apoptosis; Base Sequence; Benzamides; Cat Diseases; Cats; Cell Proliferation; Dasatinib; DNA Primers; Exons; Female; Humans; Imatinib Mesylate; In Vitro Techniques; Male; Mast Cells; Mastocytosis, Systemic; Molecular Sequence Data; Mutation; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Staurosporine; Tandem Repeat Sequences; Thiazoles

2009
Colony stimulating factor-1 receptor as a target for small molecule inhibitors.
    Bioorganic & medicinal chemistry, 2010, Mar-01, Volume: 18, Issue:5

    Topics: Benzamides; Binding Sites; Carbazoles; Computer Simulation; Dasatinib; Drug Design; Furans; Humans; Hydrogen Bonding; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor, Macrophage Colony-Stimulating Factor; Staurosporine; Sunitinib; Thiazoles

2010
H1-receptor antagonists terfenadine and loratadine inhibit spontaneous growth of neoplastic mast cells.
    Experimental hematology, 2010, Volume: 38, Issue:10

    Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cats; Cell Line, Tumor; Cell Proliferation; Dasatinib; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Histamine H1 Antagonists, Non-Sedating; Humans; Inhibitory Concentration 50; Loratadine; Mastocytoma; Mastocytosis, Systemic; Proto-Oncogene Proteins c-kit; Pyrimidines; Staurosporine; Terfenadine; Thiazoles; Tumor Cells, Cultured

2010
Systemic mastocytosis in adults: 2011 update on diagnosis, risk stratification, and management.
    American journal of hematology, 2011, Volume: 86, Issue:4

    Topics: Adult; Antineoplastic Agents; Benzamides; Bone Marrow; Cladribine; Dasatinib; Disease-Free Survival; Humans; Hydroxyurea; Imatinib Mesylate; Interferon Type I; Mast Cells; Mastocytosis, Systemic; Piperazines; Point Mutation; Proto-Oncogene Proteins c-kit; Pyrimidines; Recombinant Proteins; Risk; Staurosporine; Thiazoles

2011
Dasatinib, imatinib and staurosporine capture compounds - Complementary tools for the profiling of kinases by Capture Compound Mass Spectrometry (CCMS).
    Journal of proteomics, 2011, Dec-10, Volume: 75, Issue:1

    Topics: Benzamides; Chromatography, Liquid; Dasatinib; Gene Expression Profiling; Hep G2 Cells; Humans; Imatinib Mesylate; Liver Neoplasms; Mass Spectrometry; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Proteomics; Pyrimidines; Staurosporine; Thiazoles

2011
KIT-D816V-independent oncogenic signaling in neoplastic cells in systemic mastocytosis: role of Lyn and Btk activation and disruption by dasatinib and bosutinib.
    Blood, 2011, Aug-18, Volume: 118, Issue:7

    Topics: Agammaglobulinaemia Tyrosine Kinase; Aniline Compounds; Cell Line, Tumor; Dasatinib; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Mast Cells; Mastocytosis, Systemic; Mutation; Nitriles; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Quinolines; Signal Transduction; src-Family Kinases; Staurosporine; Thiazoles; Tumor Cells, Cultured

2011
Characterization of kinase inhibitors using different phosphorylation states of colony stimulating factor-1 receptor tyrosine kinase.
    Journal of biochemistry, 2012, Volume: 151, Issue:1

    Topics: Animals; Benzamides; Benzenesulfonates; Binding, Competitive; Cell Line; Dasatinib; Dose-Response Relationship, Drug; Humans; Imatinib Mesylate; Indazoles; Indoles; Kinetics; Niacinamide; Phenylurea Compounds; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Receptor, Macrophage Colony-Stimulating Factor; Sorafenib; Spodoptera; Staurosporine; Sulfonamides; Sunitinib; Surface Plasmon Resonance; Thiazoles; Transfection

2012
Using combination therapy to override stromal-mediated chemoresistance in mutant FLT3-positive AML: synergism between FLT3 inhibitors, dasatinib/multi-targeted inhibitors and JAK inhibitors.
    Leukemia, 2012, Volume: 26, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dasatinib; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; Humans; Janus Kinases; Leukemia, Myeloid, Acute; Mice; Mutation; Protein Kinase Inhibitors; Pyrimidines; STAT5 Transcription Factor; Staurosporine; Stromal Cells; Thiazoles

2012
Familial systemic mastocytosis with germline KIT K509I mutation is sensitive to treatment with imatinib, dasatinib and PKC412.
    Leukemia research, 2014, Volume: 38, Issue:10

    Topics: Adult; Apoptosis; Base Sequence; Benzamides; Blotting, Western; Dasatinib; Female; Germ-Line Mutation; Humans; Imatinib Mesylate; Mastocytosis, Systemic; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Staurosporine; Thiazoles; Young Adult

2014
Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells.
    Leukemia, 2018, Volume: 32, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Dasatinib; Dogs; Drug Resistance, Neoplasm; Drug Synergism; Female; G2 Phase Cell Cycle Checkpoints; Humans; Leukemia, Mast-Cell; Male; Mast Cells; Mastocytosis, Systemic; Middle Aged; Norbornanes; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; STAT5 Transcription Factor; Staurosporine; Tumor Suppressor Proteins; Young Adult

2018
An Algorithm for Building Multi-State Classifiers Based on Collision-Induced Unfolding Data.
    Analytical chemistry, 2019, 08-20, Volume: 91, Issue:16

    Topics: Algorithms; Anilides; Dasatinib; Escherichia coli; High-Throughput Screening Assays; Humans; Imidazoles; Immunoglobulin Isotypes; Models, Molecular; Multiple Myeloma; Protein Kinase Inhibitors; Protein Structure, Secondary; Pyridazines; Quinolines; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; src-Family Kinases; Static Electricity; Staurosporine

2019
Nonparametric Analysis of Thermal Proteome Profiles Reveals Novel Drug-binding Proteins.
    Molecular & cellular proteomics : MCP, 2019, Volume: 18, Issue:12

    Topics: Antineoplastic Agents; Cell Line; Dasatinib; Datasets as Topic; Drug Stability; Enzyme Inhibitors; Humans; K562 Cells; Panobinostat; Pharmaceutical Preparations; Protein Binding; Proteome; Proteomics; Sensitivity and Specificity; Software; Statistics, Nonparametric; Staurosporine; Temperature

2019