staurosporine has been researched along with colforsin in 127 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (5.51) | 18.7374 |
| 1990's | 94 (74.02) | 18.2507 |
| 2000's | 24 (18.90) | 29.6817 |
| 2010's | 2 (1.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crook, RB; Yabu, JM | 1 |
| Holmes, R; Kelly, E; Perez, HD | 1 |
| Ashcroft, SJ; Goodison, S; Kenna, S | 1 |
| Zawalich, KC; Zawalich, WS | 2 |
| Fujimoto, M; Shigeri, Y | 1 |
| Bégeot, M; Berthelon, MC; Jaillard, C; Langlois, D; Saez, JM | 1 |
| Koyama, N; Morisaki, N; Saito, Y; Yoshida, S | 1 |
| Bernhardt, J; Buhler, FR; Orlov, SN; Resink, TJ | 1 |
| Beermann, ML; Leli, U; Nixon, RA; Shea, TB | 1 |
| Bockaert, J; Curry, K; Homburger, V; Manzoni, O; Prezeau, L; Sladeczek, F | 1 |
| Andrews, PE; Montgomery, BT; Tindall, DJ; Young, CY | 1 |
| Bradbury, NA; Bridges, RJ | 1 |
| Fernandez-Gallardo, S; Guntaka, RV; Kandala, JC; Lim, RW; Shukla, SD; Tripathi, YB | 1 |
| Bennett, MV; Durand, GM; Gregor, P; Uhl, GR; Zheng, X; Zukin, RS | 1 |
| Asano, K; Iizuka, H; Ito, F; Takahashi, H; Tamura, T; Tsutsui, M | 1 |
| Tait, JF; Thiagarajan, P | 1 |
| Koch, B; Lutz-Bucher, B | 1 |
| Arneson-Rotert, LJ; Hoffman, JM; Johnson, RA; Toews, ML | 1 |
| Bryant, SH; Conte-Camerino, D | 1 |
| Jansen, PL; Ottenhoff, R; Oude Elferink, RP; Roelofsen, H | 1 |
| Anderson, RJ; Breckon, R; Colston, D | 1 |
| Perlman, RL; Ruzicka, LA; Tischler, AS | 1 |
| Fickenscher, H; Fleckenstein, B; Stamminger, T | 1 |
| Bizzarri, C; Corda, D; D'Orazio, MC; Di Girolamo, M | 1 |
| de Boland, AR; Norman, A | 1 |
| Dinarello, CA; Morse, C; Zucali, JR | 1 |
| Patke, CL; Shearer, WT | 1 |
| Bonin, PD; Chiou, WJ; McGee, JE; Singh, JP | 1 |
| Scholz, W | 1 |
| Dustin, ML; Springer, TA | 1 |
| Levin, EG; Marotti, KR; Santell, L | 1 |
| Cabot, MC; Cao, HT; Welsh, CJ; Zhang, ZC | 1 |
| Murer, H; Pfeilschifter, J; Quamme, G | 1 |
| Biber, J; Murer, H; Quamme, G | 1 |
| Fukuzaki, H; Shuntoh, H; Tanaka, C; Taniyama, K | 1 |
| Bollinger, DW; Toews, ML; Turner, JT | 1 |
| De Pont, JJ; Van Emst-de Vries, SE; Willems, PH | 1 |
| Kasuya, H; Stefansson, K; Weir, BK; White, DM | 1 |
| Adachi, I; Sasaki, K; Tsukada, T; Yamaguchi, K | 1 |
| DiBattista, JA; Iwata, K; Martel-Pelletier, J; Pelletier, JP; Zafarullah, M | 1 |
| Reich, H; Sei, Y | 1 |
| Abou-Samra, AB; Bringhurst, FR; Guo, J; Huang, X; Iida-Klein, A; Segre, GV | 1 |
| Akaike, N; Uneyama, C; Uneyama, H | 1 |
| Bellido, T; Boland, R; Fernández, LM; Morelli, S | 1 |
| Di Marzo, V; Piomelli, D; Schwartz, JC; Sokoloff, P; Vial, D | 1 |
| Good, DW | 1 |
| Aston-Jones, G; Shiekhattar, R | 1 |
| Aharon, A; Kraiem, Z; Sadeh, O; Yosef, M | 1 |
| Hall, IP; Hill, SJ; McCreath, G | 1 |
| Baumgold, J; Curran, P; Fishman, PH; Zhou, XM | 1 |
| Collins, CA; Ferro, KL; Lin, SX | 1 |
| Dekel, N; Granot, I | 1 |
| Borghini, I; Geering, K; Gjinovci, A; Pralong, WF; Wollheim, CB | 1 |
| Pimplikar, SW; Simons, K | 1 |
| Gabrielian, K; Hinton, DR; Ryan, SJ; Sakamoto, H; Sakamoto, T; Sheu, SJ | 1 |
| Armelin, HA; Armelin, MC; Kimura, E; Sonobe, MH | 1 |
| Calmus, Y; Cherqui, G; Podevin, P; Poupon, R; Robert, A | 1 |
| Berg, KA; Chen, Y; Clarke, WP; Ebersole, BJ; Maayani, S; McKay, RD | 1 |
| Hertelendy, F; Jamaluddin, M; Marrone, BL; Molnár, M | 1 |
| Meijer, DK; Merema, M; Nijholt, A; Smit, H; Steen, H | 1 |
| Fan, SF; Kao, CY; Wang, S | 1 |
| Izawa, T; Komabayashi, T; Noguchi, M; Suda, K; Tsuboi, M | 1 |
| Barajas-López, C | 1 |
| Boneh, A; Brenner, T; Shohami, E | 1 |
| Bryant, SH; Camerino, DC; Tricarico, D; Wagner, R | 1 |
| Savage, N; Weitzmann, MN | 1 |
| Davis, BB; Thomas, DJ; Zenser, TV | 1 |
| Borzecki, JS; McKay, AJ; Peterson, LN | 1 |
| Miyatake, Y; Nagai, K; Nakagawa, H; Okumura, N | 1 |
| Blum, WF; Ilvesmäki, V; Voutilainen, R | 1 |
| Hengels, KJ; Piontek, M; Porschen, R; Strohmeyer, G | 1 |
| Goligorsky, MS; Gordienko, DV; Tsukahara, H | 1 |
| Benishin, CG; Karpinski, E; Ren, J | 1 |
| Rothstein, TL; Wang, Z; Xie, H | 1 |
| Ericson, LE; Fagman, H; Nilsson, M | 1 |
| Paulding, WR; Sumners, C | 1 |
| Akaike, N; Takahashi, M; Uneyama, C; Uneyama, H | 1 |
| Abraham, EJ; Minton, JE | 1 |
| Chang, JP; Jobin, RM; Neumann, CM; Van Goor, F | 1 |
| Maruyama, K; Nishimura, E; Sasaki, K; Tsukada, T; Yamaguchi, K | 1 |
| Maruyama, K; Sasaki, K; Tsukada, T; Yamaguchi, K | 1 |
| Dawson, JJ; Iannazzo, L; Majewski, H | 1 |
| Cozza, EN; Gomez-Sanchez, CE; Lantos, CP; Pecci, A; Romero, DG | 1 |
| Coulombe, N; Lefebvre, A; LeHoux, JG | 1 |
| Bonci, A; Williams, JT | 1 |
| Hecker, M; Preiss, C; Schini-Kerth, VB | 1 |
| Nash, MS; Osborne, NN; Wood, JP | 1 |
| Levi, G; Patrizio, M; Slepko, N | 1 |
| Lee, HZ | 1 |
| Alper, SL; Izumo, S; Lee, IW; Malek, AM | 1 |
| Hashimoto, Y; Inui, K; Nagai, J; Takano, M; Yano, I | 1 |
| Borin, ML | 1 |
| Butler, K; Del Valle, J; Hare, B; Hoeltzel, M; Todisco, A; Wang, LD; Wang, M | 1 |
| Afzalov, R; Giniatullin, R; Khiroug, L; Nistri, A; Sokolova, E | 1 |
| Lippe, WR; Rubel, EW; Zirpel, L | 1 |
| Reenstra, WW; Yurko-Mauro, KA | 1 |
| Beales, IL; Calam, J; Jordinson, M | 1 |
| Anand-Srivastava, MB; Ge, C; Palaparti, A | 1 |
| Arias-Montaño, JA; Bahena-Trujillo, R | 1 |
| Chang, SH; Lin, WW; Wang, SM | 1 |
| Amara, SG; Daniels, GM | 1 |
| Ishida, H; Ishikawa, Y; Skowronski, MT | 1 |
| Diao, CT; Lau, SY; Li, L; Wong, NS; Wong, TM | 1 |
| Boiti, C; Gobbetti, A; Guelfi, G; Zampini, D; Zerani, M | 1 |
| Asbóth, G; Barlow, DH; Bellinger, J; Bernal, AL; Ledger, W; Price, SA | 1 |
| Bönisch, H; Bryan-Lluka, LJ; Paczkowski, FA | 1 |
| Kitahara, M; Naitoh, T; Tsuruzoe, N | 1 |
| Ishikawa, T; Kawai, C; Minatogawa, Y; Sano, M | 1 |
| Akaike, N; Cho, YW; Han, SH; Min, BI; Rhee, JS | 1 |
| Cho, KW; Cui, X; Jin, JY; Kim, SH; Kim, SZ; Lee, HS; Wen, JF; Xu, WX | 1 |
| Guimarães, S; Mota, A | 1 |
| Hsu, CC; Huang, BM; Huang, YL; Tsai, SJ | 1 |
| Fabbro, M; Nair, SV; Raftos, DA | 1 |
| Liao, EY; Luo, XH; Su, X; Wu, XP | 1 |
| Chakrabarti, S; Das, M; Lin, L; Rote, NS; Shivaswamy, V; Xu, B | 1 |
| Aicher, WK; Alexander, D; Franz, JK; Pap, T; Reyer, D; Schützle, H; Weis-Klemm, M | 1 |
| Huwiler, A; Pfeilschifter, J; Ren, S; Xin, C | 1 |
| Hirade, K; Ishisaki, A; Katagiri, Y; Kato, K; Kozawa, O; Nakajima, K; Nakamura, M; Niwa, M; Sugiyama, T; Tanabe, K | 1 |
| Koike, T; Suzuki, M | 1 |
| Alier, KA; Morris, BJ | 1 |
| Cho, S; Park, EM | 1 |
| Harrison, RA; Jebe, E; Petrunkina, AM; Töpfer-Petersen, E; Tsolova, M | 1 |
| Charles, A; Dharmarajan, A; White, L | 1 |
| Caruso-Neves, C; Einicker-Lamas, M; Masuda, CA; Nascimento, MT; Oliveira, MM | 1 |
| Aguilera, G; Liu, Y; Poon, V; Sanchez-Watts, G; Takemori, H; Watts, AG | 1 |
| Grygorczyk, R; Hamet, P; Koltsova, SV; Orlov, SN; Platonova, A | 1 |
127 other study(ies) available for staurosporine and colforsin
| Article | Year |
|---|---|
Calcitonin gene-related peptide stimulates intracellular cAMP via a protein kinase C-controlled mechanism in human ocular ciliary epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Calcitonin; Calcitonin Gene-Related Peptide; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Epithelium; Eye; Fetus; Humans; Kinetics; Phorbol Esters; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Regulation of formyl peptide receptor expression and its mRNA levels during differentiation of HL-60 cells.
Topics: Alkaloids; Binding Sites; Bucladesine; Cell Differentiation; Chromatography, Liquid; Colforsin; Dexamethasone; Drug Antagonism; Gene Expression Regulation; Humans; Protein Kinase C; Protein Kinases; Receptors, Formyl Peptide; Receptors, Immunologic; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1992 |
Control of insulin gene expression by glucose.
Topics: Alkaloids; Blotting, Northern; Bucladesine; Cell Line; Chimera; Chloramphenicol O-Acetyltransferase; Colforsin; Enhancer Elements, Genetic; Gene Expression Regulation; Glucose; Insulin; Islets of Langerhans; Proinsulin; Promoter Regions, Genetic; Protein Kinase C; Protein Kinases; Protein Precursors; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transfection; Verapamil | 1992 |
Biochemical mechanisms involved in monomethyl succinate-induced insulin secretion.
Topics: Alkaloids; Animals; Colforsin; Diglycerides; Glucose; In Vitro Techniques; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Succinates | 1992 |
Two different signal transductions of neuropeptide Y1 receptor in SK-N-MC cells.
Topics: Alkaloids; Calcium; Colforsin; Cyclic AMP; Diglycerides; Humans; In Vitro Techniques; Neuropeptide Y; Pertussis Toxin; Receptors, Neuropeptide Y; Second Messenger Systems; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Angiotensin II potentiates agonist-induced 3',5'-cyclic adenosine monophosphate production by cultured bovine adrenal cells through protein kinase C and calmodulin pathways.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Alkaloids; Angiotensin II; Animals; Calcium Channels; Calmodulin; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Proteins; Hydrocortisone; Nifedipine; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Trifluoperazine | 1992 |
Regulatory effects of platelet-derived growth factor-AA homodimer on migration of vascular smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Aorta, Thoracic; Biological Factors; Bucladesine; Cell Division; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Fibronectins; Isoquinolines; Kinetics; Macromolecular Substances; Muscle, Smooth, Vascular; Pertussis Toxin; Piperazines; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Wistar; Recombinant Proteins; Second Messenger Systems; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Virulence Factors, Bordetella | 1992 |
Volume-dependent regulation of sodium and potassium fluxes in cultured vascular smooth muscle cells: dependence on medium osmolality and regulation by signalling systems.
Topics: Alkaloids; Amiloride; Animals; Bumetanide; Calmodulin; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Male; Muscle, Smooth, Vascular; Osmolar Concentration; Ouabain; Phosphatidylinositols; Potassium Channels; Protein Kinase C; Rats; Rats, Inbred WKY; Rubidium Radioisotopes; Second Messenger Systems; Sodium Channels; Sodium Fluoride; Sodium Radioisotopes; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Staurosporine | 1992 |
Opposing influences of protein kinase activities on neurite outgrowth in human neuroblastoma cells: initiation by kinase A and restriction by kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Bucladesine; Colforsin; Humans; Immunohistochemistry; Isoquinolines; Nervous System Neoplasms; Neurites; Neuroblastoma; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Tumor Cells, Cultured | 1992 |
Characterization of a metabotropic glutamate receptor: direct negative coupling to adenylyl cyclase and involvement of a pertussis toxin-sensitive G protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alanine; Alkaloids; Animals; Cell Membrane; Cells, Cultured; Colforsin; Corpus Striatum; Cycloleucine; Glutamates; Glutamic Acid; GTP-Binding Proteins; In Vitro Techniques; Mice; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Signal Transduction; Staurosporine; Virulence Factors, Bordetella | 1992 |
Tumor-promoting phorbol ester down-regulates the androgen induction of prostate-specific antigen in a human prostatic adenocarcinoma cell line.
Topics: Alkaloids; Antigens, Neoplasm; Biomarkers, Tumor; Calcimycin; Colforsin; Dose-Response Relationship, Drug; Down-Regulation; Humans; Male; Nandrolone; Phorbols; Prostate-Specific Antigen; Prostatic Neoplasms; RNA, Messenger; Staurosporine; Testosterone Congeners; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Endocytosis is regulated by protein kinase A, but not protein kinase C in a secretory epithelial cell line.
Topics: Alkaloids; Animals; Calcium; Cell Line; Chlorides; Colforsin; Cyclic AMP; Dextrans; Diglycerides; Endocytosis; Epithelium; Fluorescein-5-isothiocyanate; Homeostasis; Horseradish Peroxidase; Kinetics; Protein Kinase C; Protein Kinases; Second Messenger Systems; Staurosporine; Temperature; Tetradecanoylphorbol Acetate | 1992 |
Involvement of tyrosine kinase and protein kinase C in platelet-activating-factor-induced c-fos gene expression in A-431 cells.
Topics: Alkaloids; Blotting, Northern; Cinnamates; Colforsin; Cycloheximide; Gene Expression; Genes, fos; Genistein; Humans; Isoflavones; Platelet Activating Factor; Protein Kinase C; Protein-Tyrosine Kinases; RNA; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Cloning of an apparent splice variant of the rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Colforsin; Diterpenes; Enzyme Activation; Female; Genetic Variation; Kinetics; Ligands; Molecular Sequence Data; N-Methylaspartate; Oligodeoxyribonucleotides; Oocytes; Polyamines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, N-Methyl-D-Aspartate; RNA Splicing; Sphingosine; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Xenopus laevis | 1992 |
Desensitization of the epidermal adenylate cyclase system: agonists and phorbol esters desensitize by independent mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Epidermis; Epinephrine; Histamine; Isoquinolines; Pertussis Toxin; Piperazines; Receptors, Adrenergic, beta; Receptors, Histamine; Skin; Staurosporine; Swine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Collagen-induced exposure of anionic phospholipid in platelets and platelet-derived microparticles.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine; Affinity Labels; Alkaloids; Anions; Annexin A5; Binding Sites; Blood Platelets; Bucladesine; Calcimycin; Calcium-Binding Proteins; Colforsin; Collagen; Cyclic GMP; Factor Va; Flow Cytometry; Humans; Nitroprusside; Phospholipids; Platelet Aggregation; Pregnancy Proteins; Signal Transduction; Staurosporine; Theophylline; Thromboplastin | 1991 |
Inhibition of protein kinase C activity in cultured pituitary cells attenuates both cyclic AMP-independent and -dependent secretion of ACTH.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Alkaloids; Animals; Arginine Vasopressin; Carcinogens; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Kinetics; Male; Phorbol Esters; Pituitary Gland, Anterior; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate; Veratridine | 1991 |
Serum-induced sensitization of cyclic AMP accumulation in 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Astrocytoma; Blood; Cholera Toxin; Colforsin; Culture Media; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Pertussis Toxin; Protein Kinase C; Receptors, Cell Surface; Staurosporine; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Chloride channel regulation in the skeletal muscle of normal and myotonic goats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Membrane Permeability; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Electric Conductivity; Female; Goats; Ion Channels; Isoquinolines; Male; Membrane Potentials; Muscles; Myotonia; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Staurosporine; Tetrahydropapaveroline | 1991 |
Hepatocanalicular organic-anion transport is regulated by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Anion Transport Proteins; Anions; Bile Canaliculi; Biological Transport; Bucladesine; Carrier Proteins; Colforsin; Cyclic AMP; Glucagon; Glutathione; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1991 |
Regulation by forskolin of cyclic AMP phosphodiesterase and protein kinase C activity in LLC-PK1 cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Cells, Cultured; Colforsin; Cyclic GMP; Galactose; Macaca mulatta; Pregnenolone; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Mimicry and inhibition of nerve growth factor effects: interactions of staurosporine, forskolin, and K252a in PC12 cells and normal rat chromaffin cells in vitro.
Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Alkaloids; Animals; Animals, Newborn; Axons; Carbazoles; Cell Line; Colforsin; Dihydroxyphenylalanine; Dopamine; Indole Alkaloids; Kinetics; Nerve Growth Factors; Pheochromocytoma; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine | 1990 |
Cell type-specific induction of the major immediate early enhancer of human cytomegalovirus by cyclic AMP.
Topics: Alkaloids; Animals; Antigens, Viral; Base Sequence; Cell Line; Colforsin; Cyclic AMP; Cytomegalovirus; Enhancer Elements, Genetic; Gene Expression Regulation, Viral; HeLa Cells; Humans; Immediate-Early Proteins; Molecular Sequence Data; Oligonucleotides; Plasmids; Promoter Regions, Genetic; Protein Kinase C; Repetitive Sequences, Nucleic Acid; Staurosporine; Transfection | 1990 |
Evidence that a guanine nucleotide-binding protein linked to a muscarinic receptor inhibits directly phospholipase C.
Topics: Alkaloids; Animals; Atropine; Calcimycin; Calcium; Carbachol; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cytosol; GTP-Binding Proteins; Guanosine Triphosphate; Inositol Phosphates; Kinetics; Norepinephrine; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Staurosporine; Type C Phospholipases; Virulence Factors, Bordetella | 1990 |
Evidence for involvement of protein kinase C and cyclic adenosine 3',5' monophosphate-dependent protein kinase in the 1,25-dihydroxy-vitamin D3-mediated rapid stimulation of intestinal calcium transport, (transcaltachia).
Topics: Alkaloids; Animals; Biological Transport; Calcitriol; Calcium; Chickens; Colforsin; Cyclic AMP; Duodenum; Intestinal Mucosa; Intestines; Kinetics; Male; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Vitamin D Deficiency | 1990 |
The role of protein kinase C in interleukin 1 and tumor necrosis factor alpha induction of fibroblasts to produce and release granulocyte-macrophage colony-stimulating activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Alkaloids; Bone Marrow Cells; Bucladesine; Calcium Channel Blockers; Calmodulin; Cell Line; Colforsin; Colony-Forming Units Assay; Colony-Stimulating Factors; Cyclic AMP; Fibroblasts; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Interleukin-1; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Staurosporine; Sulfonamides; Tumor Necrosis Factor-alpha | 1990 |
Enhancement of cyclic AMP metabolism in a B cell line by protein kinase C.
Topics: Alkaloids; Alprostadil; B-Lymphocytes; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Down-Regulation; Drug Synergism; Humans; Immunoglobulin M; In Vitro Techniques; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Two signal transduction pathways mediate interleukin-1 receptor expression in Balb/c3T3 fibroblasts.
Topics: Alkaloids; Animals; Cell Line; Colforsin; Cyclic AMP; Drug Synergism; Fibroblasts; Gene Expression; Interleukin-1; Mice; Mice, Inbred BALB C; Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinases; Receptors, Immunologic; Receptors, Interleukin-1; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Synergistic induction of interleukin 2 receptor (TAC) expression on YT cells by simultaneous activation of distinct signal transduction pathways.
Topics: Adenylyl Cyclases; Alkaloids; Colforsin; Humans; Interleukin-1; Killer Cells, Natural; Leukemia; Protein Kinase C; Receptors, Interleukin-2; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Antigens, Differentiation; Bucladesine; Cell Adhesion; Cell Adhesion Molecules; Colforsin; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; Micelles; Phorbol Esters; Receptors, Antigen, T-Cell; Receptors, Leukocyte-Adhesion; Staurosporine; T-Lymphocytes; Temperature | 1989 |
Protein kinase C and the stimulation of tissue plasminogen activator release from human endothelial cells. Dependence on the elevation of messenger RNA.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Northern; Calcium Channel Blockers; Cells, Cultured; Cloning, Molecular; Colforsin; Cycloheximide; DNA; Endothelium, Vascular; Humans; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator | 1989 |
Evidence for a protein kinase C-directed mechanism in the phorbol diester-induced phospholipase D pathway of diacylglycerol generation from phosphatidylcholine.
Topics: Alkaloids; Animals; Bucladesine; Cell Line; Choline; Colforsin; Diglycerides; Embryo, Mammalian; Fibroblasts; Glycerides; Glycerophospholipids; Hydrolysis; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipases; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Parathyroid hormone inhibition of Na+/phosphate cotransport in OK cells: requirement of protein kinase C-dependent pathway.
Topics: Alkaloids; Animals; Biological Transport; Carrier Proteins; Cell Line; Colforsin; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Kidney; Opossums; Parathyroid Hormone; Protein Kinase C; Sodium-Phosphate Cotransporter Proteins; Staurosporine; Symporters; Tetradecanoylphorbol Acetate | 1989 |
Sodium-phosphate cotransport in OK cells: inhibition by PTH and "adaptation" to low phosphate.
Topics: Alkaloids; Animals; Bucladesine; Carrier Proteins; Cell Line; Colforsin; Kidney; Kinetics; Parathyroid Hormone; Peptide Fragments; Phosphates; Sodium-Phosphate Cotransporter Proteins; Staurosporine; Symporters; Teriparatide; Tetradecanoylphorbol Acetate | 1989 |
Inhibition by cyclic AMP of phorbol ester-potentiated norepinephrine release from guinea pig brain cortical synaptosomes.
Topics: Alkaloids; Animals; Bucladesine; Carbazoles; Cerebral Cortex; Colforsin; Cyclic AMP; Enzyme Activation; Female; Guinea Pigs; Indoles; Male; Norepinephrine; Polymyxin B; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Staurosporine; Synaptosomes; Tetradecanoylphorbol Acetate | 1988 |
Vasoactive intestinal peptide receptor/adenylate cyclase system: differences between agonist- and protein kinase C-mediated desensitization and further evidence for receptor internalization.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Alkaloids; Animals; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoquinolines; Peptide PHI; Piperazines; Protein Kinase C; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Staurosporine; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1988 |
Cholecystokinin-stimulated enzyme secretion from dispersed rabbit pancreatic acinar cells: phosphorylation-dependent changes in potency and efficacy.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Amylases; Animals; Calcium-Transporting ATPases; Cells, Cultured; Cholecystokinin; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Pancreas; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Sincalide; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1995 |
Mechanism of oxyhemoglobin-induced release of endothelin-1 from cultured vascular endothelial cells and smooth-muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Blotting, Northern; Cattle; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Methemoglobin; Muscle, Smooth, Vascular; Oxyhemoglobins; Protein Kinase C; Rats; Reference Values; RNA; RNA, Messenger; Staurosporine; Thrombin | 1993 |
Staurosporine potentiates cAMP-mediated promoter activity of the vasoactive intestinal polypeptide gene in rat pheochromocytoma PC12 cells.
Topics: Adrenal Gland Neoplasms; Alkaloids; Animals; beta-Galactosidase; Colforsin; Cyclic AMP; Enzyme Inhibitors; Humans; Kinetics; Neurites; Neuroblastoma; PC12 Cells; Pheochromocytoma; Promoter Regions, Genetic; Protein Kinase C; Rats; Recombinant Proteins; Staurosporine; Transfection; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 1995 |
Interleukin-1 beta induction of tissue inhibitor of metalloproteinase (TIMP-1) is functionally antagonized by prostaglandin E2 in human synovial fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Northern; Bucladesine; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Glycoproteins; Humans; Immunoenzyme Techniques; Interleukin-1; Isoquinolines; Metalloendopeptidases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Recombinant Proteins; RNA, Messenger; Staurosporine; Synovial Membrane; Tetradecanoylphorbol Acetate; Thionucleotides; Tissue Inhibitor of Metalloproteinases; Up-Regulation | 1995 |
Thapsigargin induces IL-2 receptor alpha-chain in human peripheral and Jurkat T cells via a protein kinase C-independent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Base Sequence; Calcimycin; Calcium; Calcium-Transporting ATPases; Cholera Toxin; Colforsin; Drug Synergism; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Humans; Hydroquinones; Isoquinolines; Leukemia-Lymphoma, Adult T-Cell; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; Piperazines; Protein Kinase C; Receptors, Interleukin-2; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Staurosporine; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Parathyroid hormone (PTH)/PTH-related peptide receptor density modulates activation of phospholipase C and phosphate transport by PTH in LLC-PK1 cells.
Topics: Adenylyl Cyclases; Alkaloids; Animals; Biological Transport; Calcitonin; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Hydrolysis; Inositol Phosphates; Kidney; LLC-PK1 Cells; Parathyroid Hormone; Phorbol Esters; Phosphates; Protein Kinase C; Receptor, Parathyroid Hormone, Type 1; Receptors, Parathyroid Hormone; Second Messenger Systems; Staurosporine; Swine; Type C Phospholipases | 1995 |
Intracellular mechanisms of cytoplasmic Ca2+ oscillation in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Alkaloids; Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Calmodulin; Colforsin; Cyclic AMP; Cytoplasm; Egtazic Acid; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Megakaryocytes; Models, Biological; Oscillometry; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Trifluoperazine | 1993 |
Evidence for the participation of protein kinase C and 3',5'-cyclic AMP-dependent protein kinase in the stimulation of muscle cell proliferation by 1,25-dihydroxy-vitamin D3.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Bucladesine; Calcitriol; Calcium; Calcium Channels; Cell Division; Cells, Cultured; Chick Embryo; Colforsin; Diglycerides; DNA; Dose-Response Relationship, Drug; Muscles; Nifedipine; Protein Kinase C; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaloids; Animals; Arachidonic Acid; Calcimycin; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diglycerides; Diterpenes; Dopamine D2 Receptor Antagonists; Ergolines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Protein Kinase C; Quinpirole; Raclopride; Receptors, Dopamine D2; Recombinant Proteins; Salicylamides; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Hyperosmolality inhibits bicarbonate absorption in rat medullary thick ascending limb via a protein-tyrosine kinase-dependent pathway.
Topics: Absorption; Alkaloids; Animals; Arginine Vasopressin; Benzoquinones; Bicarbonates; Colforsin; Dinoprostone; Drug Interactions; Genistein; Isoflavones; Kidney Medulla; Lactams, Macrocyclic; Loop of Henle; Mannitol; Molybdenum; Osmolar Concentration; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Sodium Chloride; Staurosporine | 1995 |
Activation of adenylate cyclase attenuates the hyperpolarization following single action potentials in brain noradrenergic neurons independently of protein kinase A.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adenylyl Cyclases; Alkaloids; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; In Vitro Techniques; Indoles; Isoquinolines; Locus Coeruleus; Neurons; Norepinephrine; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Staurosporine; Thionucleotides | 1994 |
Mutual antagonistic interactions between the thyrotropin (adenosine 3',5'-monophosphate) and protein kinase C/epidermal growth factor (tyrosine kinase) pathways in cell proliferation and differentiation of cultured human thyroid follicles.
Topics: Alkaloids; Cell Differentiation; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Epidermal Growth Factor; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Second Messenger Systems; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1995 |
Agonist-induced desensitization of histamine H1 receptor-mediated inositol phospholipid hydrolysis in human umbilical vein endothelial cells.
Topics: Alkaloids; Cells, Cultured; Colforsin; Endothelium, Vascular; Histamine; Humans; Hydrolysis; Indoles; Nitroprusside; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Receptors, Histamine H1; Sodium Fluoride; Staurosporine; Umbilical Veins | 1994 |
Modulation of adenylylcyclase by protein kinase C in human neurotumor SK-N-MC cells: evidence that the alpha isozyme mediates both potentiation and desensitization.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Alkaloids; Aluminum Compounds; Animals; Brain; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Dopamine; Drug Synergism; Fluorides; GTP-Binding Proteins; Humans; Isoenzymes; Isoproterenol; Kinetics; Manganese; Neuroblastoma; Neuropeptide Y; Propanolamines; Protein Kinase C; Rats; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Alkaloids; Animals; Bucladesine; Calcimycin; Calmodulin; Cell Line; Colforsin; Culture Media; Cytoplasm; Dyneins; Edetic Acid; Ethers, Cyclic; Imidazoles; Kidney; Kinetics; Macromolecular Substances; Okadaic Acid; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate | 1994 |
Phosphorylation and expression of connexin-43 ovarian gap junction protein are regulated by luteinizing hormone.
Topics: Alkaloids; Animals; Blotting, Northern; Blotting, Western; Cells, Cultured; Colforsin; Connexin 43; Electrophoresis, Polyacrylamide Gel; Female; Gap Junctions; Gene Expression; Granulosa Cells; Kinetics; Luteinizing Hormone; Meiosis; Ovarian Follicle; Ovary; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
In vivo phosphorylation of the Na,K-ATPase alpha subunit in sciatic nerves of control and diabetic rats: effects of protein kinase modulators.
Topics: Alkaloids; Animals; Blotting, Western; Calcium; Colforsin; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Isoenzymes; Kinetics; Macromolecular Substances; Male; Membrane Proteins; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Reference Values; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Activators of protein kinase A stimulate apical but not basolateral transport in epithelial Madin-Darby canine kidney cells.
Topics: Alkaloids; Aluminum Compounds; Animals; Biological Transport; Cell Line; Cell Membrane; Cell Polarity; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dogs; Endoplasmic Reticulum; Enzyme Activation; Epithelium; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Hemagglutinins; In Vitro Techniques; Kidney; Membrane Glycoproteins; Phorbol 12,13-Dibutyrate; Phosphoproteins; Staurosporine; Viral Envelope Proteins | 1994 |
Intercellular gap formation induced by thrombin in confluent cultured bovine retinal pigment epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Alkaloids; Animals; Cattle; Cells, Cultured; Colforsin; Cytoskeleton; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Gap Junctions; Isoquinolines; Pigment Epithelium of Eye; Piperazines; Protein Kinase Inhibitors; Staurosporine; Thrombin; Time Factors; Vinculin | 1994 |
Induction of FOS and JUN proteins by adrenocorticotropin and phorbol ester but not by 3',5'-cyclic adenosine monophosphate derivatives.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Alkaloids; Animals; Bucladesine; Colforsin; Cycloheximide; Dactinomycin; Enzyme Induction; Genes, fos; Genes, jun; Kinetics; Mice; Neoplasm Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Inhibition of procoagulant activity of human monocytes by chenodeoxycholic acid: involvement of protein kinase C.
Topics: Alkaloids; Blood Coagulation; Bucladesine; Chenodeoxycholic Acid; Colforsin; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Humans; Monocytes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
5-Hydroxytryptamine type 2A receptors regulate cyclic AMP accumulation in a neuronal cell line by protein kinase C-dependent and calcium/calmodulin-dependent mechanisms.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alkaloids; Animals; Calcium; Calmodulin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Inositol Phosphates; Neurons; Protein Kinase C; Rats; Receptors, Serotonin; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Signal transduction in avian granulosa cells: effects of protein kinase C inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Chickens; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Female; Granulosa Cells; Inositol Phosphates; Isoquinolines; Piperazines; Progesterone; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Modulators of the protein kinase C system influence biliary excretion of cationic drugs.
Topics: Alkaloids; Animals; Bile; Biological Transport, Active; Carrier Proteins; Cations; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Glucagon; In Vitro Techniques; Liver; Male; Perfusion; Protein Kinase C; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1993 |
The transduction system in the isoproterenol activation of the Ca(2+)-activated K+ channel in guinea pig taenia coli myocytes.
Topics: Adenylyl Cyclases; Alkaloids; Animals; Bucladesine; Calcium; Calcium Channel Blockers; Cholera Toxin; Colforsin; Colon; Cyclic AMP-Dependent Protein Kinases; Gallic Acid; GTP-Binding Proteins; Guanosine Diphosphate; Guinea Pigs; Isoproterenol; Membrane Potentials; Muscles; Potassium Channels; Protein Kinase C; Signal Transduction; Staurosporine; Thionucleotides | 1993 |
Mechanism of isoprenaline-stimulated diacylglycerol formation in rat parotid acinar cells.
Topics: Alkaloids; Animals; Bucladesine; Cells, Cultured; Colforsin; Diglycerides; In Vitro Techniques; Isoproterenol; Kinetics; Male; Parotid Gland; Phentolamine; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Propranolol; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Staurosporine; Stimulation, Chemical; Vasoactive Intestinal Peptide | 1993 |
Adenosine reduces the potassium conductance of guinea pig submucosal plexus neurons by activating protein kinase A.
Topics: 2-Chloroadenosine; Adenosine; Alkaloids; Animals; Cadmium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Guinea Pigs; Membrane Potentials; Neurons; Phorbol 12,13-Dibutyrate; Potassium; Staurosporine; Submucous Plexus | 1993 |
Differential effects of phorbol myristate acetate and dexamethasone on protein kinase C activity and eicosanoids production in cultured rat astrocytes.
Topics: Alkaloids; Animals; Astrocytes; Biomarkers; Cells, Cultured; Colforsin; Dexamethasone; Dinoprostone; Eicosanoids; Female; Fluorescent Antibody Technique; Neuroglia; Pregnancy; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Regulation of resting ionic conductances in frog skeletal muscle.
Topics: Adenylyl Cyclases; Alkaloids; Animals; Chlorides; Colforsin; Electric Conductivity; Electrophysiology; Enzyme Activation; Muscles; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rana esculenta; Staurosporine | 1993 |
Cyclic adenosine 3',5'-monophosphate, a second messenger in interleukin-1 mediated K562 cytostasis.
Topics: Adenylyl Cyclases; Alkaloids; Bucladesine; Cell Division; Colforsin; Cyclic AMP; Humans; Interleukin-1; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Cyclic adenosine monophosphate response in primary and subcultured bladder epithelial cells: inhibition by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Alkaloids; Animals; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Dogs; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Epithelium; Indomethacin; Models, Biological; Protein Kinase C; Second Messenger Systems; Signal Transduction; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Urinary Bladder | 1993 |
Endogenous prostaglandin E2 mediates inhibition of rat thick ascending limb Cl reabsorption in chronic hypercalcemia.
Topics: Alkaloids; Animals; Biological Transport, Active; Chlorides; Chronic Disease; Colforsin; Cyclic AMP; Dihydrotachysterol; Dinoprostone; Furosemide; Hypercalcemia; In Vitro Techniques; Indomethacin; Kidney Medulla; Kidney Tubules, Collecting; Male; Perfusion; Rats; Rats, Sprague-Dawley; Staurosporine | 1993 |
The signal transduction pathway for VGF expression due to NGF is different from that due to bFGF in PC12h cell.
Topics: Alkaloids; Animals; Bucladesine; Colforsin; Deoxyadenosines; Fibroblast Growth Factor 2; Heparin; Molecular Weight; Nerve Growth Factors; PC12 Cells; Potassium Chloride; Protein Biosynthesis; Protein Kinase C; Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleosides | 1993 |
Insulin-like growth factor-II in human fetal adrenals: regulation by ACTH, protein kinase C and growth factors.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Alkaloids; Blotting, Northern; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Gene Expression; Gene Expression Regulation; Genes; Growth Substances; Humans; Insulin-Like Growth Factor II; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1993 |
Protein kinase C and adenylate cyclase as targets for growth inhibition of human gastric cancer cells.
Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkaloids; Bucladesine; Cell Division; Colforsin; Enzyme Activation; Humans; Protein Kinase C; Staurosporine; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Continuous monitoring of nitric oxide release from human umbilical vein endothelial cells.
Topics: Alkaloids; Arginine; Bradykinin; Cells, Cultured; Colforsin; Endothelium, Vascular; Enzyme Activation; Humans; Ionomycin; Kinetics; Nitric Oxide; Polarography; Protein Kinase C; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Umbilical Veins | 1993 |
The actions of prostaglandin E2 on potassium currents in rat tail artery vascular smooth muscle cells: regulation by protein kinase A and protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Male; Muscle, Smooth, Vascular; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Tail; Tetradecanoylphorbol Acetate | 1996 |
Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibodies, Anti-Idiotypic; Antigens, CD; B-Lymphocytes; B7-2 Antigen; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Immunoglobulins; Ionomycin; Isoquinolines; Lymphoma, B-Cell; Membrane Glycoproteins; Mice; Molecular Sequence Data; Phosphorylation; Piperazines; Protein Kinase C; Rats; Receptors, Antigen, B-Cell; Signal Transduction; Staurosporine; Sulfonamides | 1996 |
Ca2+-dependent and Ca2+-independent regulation of the thyroid epithelial junction complex by protein kinases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Epithelium; Isoquinolines; Membrane Proteins; Phosphoproteins; Piperazines; Staurosporine; Swine; Thyroid Gland; Thyrotropin; Tight Junctions; Trypsin; Zonula Occludens-1 Protein | 1996 |
Protein kinase C modulates natriuretic peptide receptors in astroglial cultures from rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Animals, Newborn; Astrocytes; Atrial Natriuretic Factor; Binding Sites; Brain Stem; Cells, Cultured; Colforsin; Cyclic GMP; Down-Regulation; Enzyme Inhibitors; Hypothalamus; Kinetics; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Staurosporine; Tetradecanoylphorbol Acetate; Up-Regulation | 1996 |
Pharmacological studies on mechanisms involved in Ca2+ oscillations in rat megakaryocytes.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Calcium; Calcium-Transporting ATPases; Calmodulin; Colforsin; Female; Indoles; Male; Megakaryocytes; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Effects of corticotropin-releasing hormone, lysine vasopressin, oxytocin, and angiotensin II on adrenocorticotropin secretion from porcine anterior pituitary cells.
Topics: Adrenocorticotropic Hormone; Alkaloids; Angiotensin II; Animals; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Synergism; Lypressin; Oxytocin; Pituitary Gland, Anterior; Protein Kinase C; Radioimmunoassay; Signal Transduction; Staurosporine; Swine; Tetradecanoylphorbol Acetate | 1996 |
Interactions between signaling pathways in mediating GnRH-stimulated GTH release from goldfish pituitary cells: protein kinase C, but not cyclic AMP is an important mediator of GnRH-stimulated gonadotropin secretion in goldfish.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Arachidonic Acid; Calcium Channel Agonists; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Goldfish; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Male; Microspheres; Naphthalenes; Pituitary Gland; Potassium; Protein Kinase C; Salmon; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Decrease in neuron-restrictive silencer factor (NRSF) mRNA levels during differentiation of cultured neuroblastoma cells.
Topics: Actins; Brain Neoplasms; Carcinogens; Cell Differentiation; Colforsin; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Pheochromocytoma; Polymerase Chain Reaction; Repressor Proteins; RNA, Messenger; Staurosporine; Transcription Factors; Tumor Cells, Cultured | 1996 |
Long-term regulation of synapsin I gene expression and neuronal morphology by cyclic AMP and low-dose staurosporine.
Topics: Adenylyl Cyclases; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP; DNA Primers; Dopamine beta-Hydroxylase; Humans; Kinetics; Neuroblastoma; Neurons; Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Synapsins; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Muscarinic autoinhibition of acetylcholine release in mouse atria is not transduced through cyclic AMP or protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenylyl Cyclases; Animals; Atrial Function; Atropine; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Heart; Heart Atria; In Vitro Techniques; Male; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; Second Messenger Systems; Staurosporine | 1996 |
Effects of staurosporine on ACTH-mediated stimulation of aldosterone production.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Bucladesine; Cells, Cultured; Colforsin; Cosyntropin; Dose-Response Relationship, Drug; Male; Peptide Fragments; Protein Kinase C; Rats; Staurosporine; Zona Glomerulosa | 1996 |
Characterization of the hamster CYP11B2 gene regulatory regions.
Topics: Adrenal Cortex Neoplasms; Animals; Blotting, Southern; Chloramphenicol O-Acetyltransferase; Colforsin; Cricetinae; Cyclic AMP; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Genetic Vectors; Mice; Promoter Regions, Genetic; Protein Kinase C; Recombinant Fusion Proteins; Staurosporine; TATA Box; Transfection; Tumor Cells, Cultured | 1996 |
Increased probability of GABA release during withdrawal from morphine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Antagonists; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Interneurons; Morphine; Nerve Tissue Proteins; Organophosphorus Compounds; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Picrotoxin; Receptors, GABA-A; Salicylamides; Serotonin; Signal Transduction; Staurosporine; Strychnine; Substance Withdrawal Syndrome; Tegmentum Mesencephali; Thionucleotides | 1997 |
Induction by staurosporine of nitric oxide synthase expression in vascular smooth muscle cells: role of NF-kappa B, CREB and C/EBP beta.
Topics: Animals; Aorta, Thoracic; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Colforsin; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Enzyme Induction; Enzyme Inhibitors; Interleukin-1; Male; Muscle, Smooth, Vascular; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nuclear Proteins; Protein Kinase C; Rats; Rats, Inbred WKY; RNA, Messenger; Staurosporine; Transcription Factors | 1997 |
Protein kinase C activation by serotonin potentiates agonist-induced stimulation of cAMP production in cultured rat retinal pigment epithelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Isoproterenol; Naphthalenes; Phorbol 12,13-Dibutyrate; Pigment Epithelium of Eye; Protein Kinase C; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Staurosporine | 1997 |
Opposite regulation of adenylyl cyclase by protein kinase C in astrocyte and microglia cultures.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Astrocytes; Cell Membrane; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cytosol; Enzyme Inhibitors; Homeostasis; Isoproterenol; Kinetics; Microglia; Naphthalenes; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Inhibitory effect of 2-phenyl-4-quinolone on serotonin-mediated changes in the morphology and permeability of endothelial monolayers.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Cattle; Cell Size; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium; Enzyme Inhibitors; Gap Junctions; Myocardium; Nitroprusside; Permeability; Protein Kinase C; Quinolones; Rats; Serotonin; Serum Albumin; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Regulation of endothelin-1 gene expression by cell shape and the microfilament network in vascular endothelium.
Topics: Actin Cytoskeleton; Actins; Animals; Aorta; Cattle; Cell Size; Cells, Cultured; Colforsin; Cytochalasin D; Cytoskeleton; Endothelin-1; Endothelium, Vascular; Gene Expression Regulation; Genistein; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
Inhibition of PAH transport by parathyroid hormone in OK cells: involvement of protein kinase C pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Bucladesine; Cell Line; Cell Membrane; Colforsin; Kidney; Kinetics; Mannitol; p-Aminohippuric Acid; Protein Kinase C; Second Messenger Systems; Staurosporine; Teriparatide; Tetradecanoylphorbol Acetate | 1997 |
Roles of PKA and PKC in regulation of Na+ pump activity in vascular smooth muscle cells.
Topics: Animals; Aorta; Arginine Vasopressin; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Homeostasis; Isoproterenol; Kinetics; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Staurosporine | 1997 |
Activation of the human histamine H2 receptor is linked to cell proliferation and c-fos gene transcription.
Topics: Cell Division; Cell Line; Cimetidine; Cloning, Molecular; Colforsin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; Epinephrine; Genes, fos; Genes, Reporter; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; Luciferases; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins c-fos; Receptors, Histamine H2; Recombinant Fusion Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1997 |
Recovery from desensitization of neuronal nicotinic acetylcholine receptors of rat chromaffin cells is modulated by intracellular calcium through distinct second messengers.
Topics: Animals; Calcineurin; Calcium; Carcinogens; Chromaffin Cells; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Ion Channel Gating; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; PC12 Cells; Phorbol Esters; Phosphoprotein Phosphatases; Protein Kinase C; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Receptors, Nicotinic; Second Messenger Systems; Staurosporine; Thionucleotides | 1998 |
Activity-dependent regulation of [Ca2+]i in avian cochlear nucleus neurons: roles of protein kinases A and C and relation to cell death.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Apoptosis; Autonomic Denervation; Brain Stem; Calcium; Chick Embryo; Cochlear Nucleus; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Enzyme Activation; Estrenes; Homeostasis; Indoles; Ion Transport; Maleimides; Nerve Tissue Proteins; Protein Kinase C; Pyrrolidinones; Receptors, Metabotropic Glutamate; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides | 1998 |
Prostaglandin F2alpha stimulates CFTR activity by PKA- and PKC-dependent phosphorylation.
Topics: 3T3 Cells; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprost; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Iodides; Isoquinolines; Kinetics; Mice; Phosphopeptides; Phosphorylation; Protein Kinase C; Recombinant Proteins; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Soybean agglutinin stimulated cholecystokinin release from cultured rabbit jejunal cells requires calcium influx via L-type calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Separation; Cells, Cultured; Cholecystokinin; Colforsin; Enzyme Activation; Jejunum; Lectins; Male; Phenylalanine; Plant Lectins; Protein Kinase C; Rabbits; Radioimmunoassay; Somatostatin; Soybean Proteins; Staurosporine; Verapamil | 1998 |
Angiotensin II enhances the expression of Gialpha in A10 cells (smooth muscle): relationship with adenylyl cyclase activity.
Topics: Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cell Line; Colforsin; Dactinomycin; Dose-Response Relationship, Drug; Drug Interactions; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Muscle, Smooth, Vascular; Peptide Fragments; Protein Kinase C; Rats; Staurosporine | 1999 |
[3H] gamma-aminobutyric acid transport in rat substantia nigra pars reticulata synaptosomes: pharmacological characterization and phorbol ester-induced inhibition.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Basal Ganglia; beta-Alanine; Biological Transport; Carcinogens; Colforsin; Enzyme Inhibitors; GABA Agents; gamma-Aminobutyric Acid; Nipecotic Acids; Proline; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Substantia Nigra; Synaptosomes; Tetradecanoylphorbol Acetate; Tritium | 1999 |
Roles of atypical protein kinase C in lysophosphatidic acid-induced type II adenylyl cyclase activation in RAW 264.7 macrophages.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; Calcium; Cell Line; Cholera Toxin; Colchicine; Colforsin; Cyclic AMP; Cytochalasin B; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Indoles; Isoenzymes; Isoproterenol; Lysophosphatidylcholines; Lysophospholipids; Macrophages; Pertussis Toxin; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1999 |
Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters.
Topics: Acetylcysteine; Animals; Carrier Proteins; Cell Line; Chloroquine; Clathrin; Colforsin; Cycloheximide; Dogs; Dopamine; Dopamine Plasma Membrane Transport Proteins; Endocytosis; Enzyme Activation; Humans; Kinetics; Lysosomes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phorbols; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1999 |
Enhancement by epinephrine of benzylpenicillin transport in rat small intestine.
Topics: Acetylcholine; Adrenergic Agonists; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Animals; Bucladesine; Cholinergic Agonists; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diet; Enzyme Inhibitors; Epinephrine; Intestine, Small; Isoquinolines; Male; Penicillin G; Penicillins; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Staurosporine | 2000 |
kappa-Opioid receptor potentiates apoptosis via a phospholipase C pathway in the CNE2 human epithelial tumor cell line.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenine; Apoptosis; Base Sequence; Benzomorphans; Cell Membrane; Colforsin; Cyclic AMP; Dideoxyadenosine; Drug Synergism; Epithelial Cells; Estrenes; Humans; Molecular Sequence Data; Pyrrolidinones; Receptors, Opioid, kappa; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Staurosporine; Tumor Cells, Cultured; Type C Phospholipases | 2000 |
Prostaglandin receptors and role of G protein-activated pathways on corpora lutea of pseudopregnant rabbit in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Analysis of Variance; Animals; Colforsin; Corpus Luteum; Culture Techniques; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Imipramine; Luteal Phase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Progesterone; Protein Kinase C; Pseudopregnancy; Rabbits; Receptors, Prostaglandin; Receptors, Prostaglandin E; Signal Transduction; Statistics, Nonparametric; Staurosporine; Type C Phospholipases | 2001 |
Characterization of adenylyl cyclases in cultured human granulosa cells.
Topics: Adenylyl Cyclases; Calcimycin; Calcium; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Female; Granulosa Cells; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Isoenzymes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 2001 |
Effects of short- and long-term exposure to c-AMP and c-GMP on the noradrenaline transporter.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Bucladesine; Carrier Proteins; Cholera Toxin; Colforsin; COS Cells; Cyclic AMP; Cyclic GMP; Humans; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; PC12 Cells; Rats; RNA, Messenger; Staurosporine; Symporters; Time Factors; Tumor Cells, Cultured | 2001 |
Tumor necrosis factor-alpha is induced through phorbol ester--and glycated human albumin-dependent pathway in THP-1 cells.
Topics: Carcinogens; Catalase; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Insulin Resistance; Mitogen-Activated Protein Kinases; Monocytes; Protein Kinase C; Serum Albumin; Signal Transduction; Staurosporine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Effects of protein kinase C inhibitors on insulin secretory responses from rodent pancreatic islets.
Topics: Animals; Carbachol; Carbazoles; Cholinergic Agonists; Colforsin; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Glucose; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Mice; Potassium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate | 2001 |
Peroxisomes exist in growth cones and move anterogradely and retrogradely in neurites of PC12D cells.
Topics: Amino Acid Motifs; Animals; Bucladesine; Colforsin; Green Fluorescent Proteins; Growth Cones; Kinetics; Luminescent Proteins; Models, Neurological; Movement; Neurites; PC12 Cells; Peroxisomes; Rats; Recombinant Fusion Proteins; Staurosporine | 2001 |
Antagonizing effect of protein kinase C activation on the mu-opioid agonist-induced inhibition of high voltage-activated calcium current in rat periaqueductal gray neuron.
Topics: Analgesics, Opioid; Animals; Calcium Channels; Calcium Signaling; Carcinogens; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Female; Male; Membrane Potentials; Neurons; Pain; Periaqueductal Gray; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Staurosporine; Synaptic Transmission; Tetradecanoylphorbol Acetate | 2001 |
Protein kinase-dependent and Ca(2+)-independent cAMP inhibition of ANP release in beating rabbit atria.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Atrial Function; Atrial Natriuretic Factor; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Indoles; Myocardial Contraction; Myocardium; Nifedipine; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Rabbits; Staurosporine | 2002 |
Interaction between alpha2-autoreceptors and receptors mediating the effects of angiotensin II and bradykinin in the heart of newborn rats.
Topics: Adrenergic alpha-Antagonists; Alkaloids; Angiotensin II; Animals; Animals, Newborn; Autoreceptors; Benzophenanthridines; Bradykinin; Colforsin; Electric Stimulation; In Vitro Techniques; Myocardium; Norepinephrine; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Bradykinin; Staurosporine; Yohimbine | 2002 |
Regulatory mechanism of Cordyceps sinensis mycelium on mouse Leydig cell steroidogenesis.
Topics: Androstenedione; Animals; Cells, Cultured; Colforsin; Cordyceps; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Hydroxycholesterols; Isoquinolines; Leydig Cells; Male; Mice; Mice, Inbred C57BL; Mycelium; Progestins; Protein Kinase C; Staurosporine; Sulfonamides; Testosterone; Tetradecanoylphorbol Acetate | 2003 |
Exocytosis of a complement component C3-like protein by tunicate hemocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Calcimycin; Carrageenan; Cell Survival; Cholera Toxin; Colchicine; Colforsin; Complement C3; Cytochalasin D; Cytoplasmic Vesicles; Enzyme-Linked Immunosorbent Assay; Exocytosis; Hemocytes; Immunohistochemistry; Kinetics; Lipopolysaccharides; Mannans; Microscopy, Electron; Phenanthridines; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Urochordata | 2004 |
Parathyroid hormone inhibits the expression of membrane-type matrix metalloproteinase-1 (MT1-MMP) in osteoblast-like MG-63 cells.
Topics: Blotting, Northern; Blotting, Western; Carrier Proteins; Cell Line, Tumor; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Gene Expression; Humans; Isoquinolines; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Membrane Glycoproteins; Metalloendopeptidases; Osteoblasts; Protein Kinase C; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Signal Transduction; Staurosporine; Sulfonamides; Teriparatide | 2004 |
Phosphatidylserine efflux and intercellular fusion in a BeWo model of human villous cytotrophoblast.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Differentiation; Cell Fusion; Cell Line, Tumor; Cell Membrane; Colforsin; Cysteine Proteinase Inhibitors; Cytochromes c; Cytosol; DNA Fragmentation; Flavoproteins; Humans; Lamin Type B; Membrane Lipids; Membrane Potentials; Membrane Proteins; Microscopy, Fluorescence; Mitochondria; Models, Biological; Phosphatidylserines; Staurosporine; Trophoblasts; Vanadates | 2004 |
Synovial fibroblasts from rheumatoid arthritis patients differ in their regulation of IL-16 gene activity in comparison to osteoarthritis fibroblasts.
Topics: Arthritis, Rheumatoid; Cell Extracts; Cells, Cultured; Colforsin; Cyclic AMP; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-16; Osteoarthritis; Protein Serine-Threonine Kinases; RNA, Messenger; Signal Transduction; Staurosporine; Synovial Membrane | 2004 |
Heterologous desensitization of the sphingosine-1-phosphate receptors by purinoceptor activation in renal mesangial cells.
Topics: Adenosine; Adenosine Triphosphate; Animals; Biotransformation; Blotting, Western; Cells, Cultured; Colforsin; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Protein Kinases; Purinergic Agonists; Purinergic P1 Receptor Agonists; Rats; Receptors, Lysosphingolipid; Sphingosine; Staurosporine | 2004 |
Adenylyl cyclase-cAMP system inhibits thrombin-induced HSP27 in vascular smooth muscle cells.
Topics: Adenine; Adenylyl Cyclases; Animals; Base Sequence; Cell Line; Colforsin; Cyclic AMP; DNA Primers; Heat-Shock Proteins; Muscle, Smooth, Vascular; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Rats; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 2005 |
Early apoptotic and late necrotic components associated with altered Ca2+ homeostasis in a peptide-delivery model of polyglutamine-induced neuronal death.
Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Caspase 3; Caspase 7; Caspases; Cell Count; Cells, Cultured; Colforsin; Cyclin D1; Cycloheximide; Dihydrotachysterol; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Homeostasis; Immunohistochemistry; In Situ Nick-End Labeling; Ionophores; Lactic Acid; Mitochondria; Models, Biological; Necrosis; Nerve Growth Factor; Neurons; Neuroprotective Agents; Peptides; Permeability; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-jun; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Superior Cervical Ganglion; Time Factors | 2005 |
Divergent regulation of Pyk2/CAKbeta phosphorylation by Ca2+ and cAMP in the hippocampus.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcimycin; Calcium; Colforsin; Cyclic AMP; Focal Adhesion Kinase 2; Hippocampus; Immunoblotting; Immunoprecipitation; Long-Term Potentiation; Phenanthridines; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Staurosporine | 2005 |
Enhanced ERK dependent CREB activation reduces apoptosis in staurosporine-treated human neuroblastoma SK-N-BE(2)C cells.
Topics: Analysis of Variance; Apoptosis; Blotting, Western; Butadienes; Caspase 3; Cell Line, Tumor; Colforsin; Collagen Type XI; CREB-Binding Protein; Dopamine; Drug Interactions; Enzyme Inhibitors; Humans; Mitogen-Activated Protein Kinases; Neuroblastoma; Nitriles; Staurosporine | 2006 |
Signalling pathways involved in the control of sperm cell volume.
Topics: Animals; Cell Size; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indoles; Ion Channels; Male; Maleimides; Marine Toxins; Okadaic Acid; Osmosis; Oxazoles; Papaverine; Phosphoprotein Phosphatases; Protein Kinase C; Signal Transduction; Spermatozoa; Staurosporine; Swine | 2007 |
Caspase-14: a new player in cytotrophoblast differentiation.
Topics: Apoptosis; Caspase 14; Cell Differentiation; Cell Line, Tumor; Colforsin; Humans; Keratinocytes; Placenta; RNA, Messenger; Signal Transduction; Staurosporine; Time Factors; Trophoblasts; Up-Regulation | 2007 |
Trypanosoma cruzi epimastigotes: regulation of myo-inositol transport by effectors of protein kinases A and C.
Topics: Animals; Biological Transport; Bucladesine; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Inositol; Kinetics; Phosphorylation; Protein Kinase C; Pyrroles; Signal Transduction; Sphingosine; Staurosporine; Trypanosoma cruzi | 2007 |
Salt-inducible kinase is involved in the regulation of corticotropin-releasing hormone transcription in hypothalamic neurons in rats.
Topics: Active Transport, Cell Nucleus; Animals; Base Sequence; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; DNA Primers; Gene Knockdown Techniques; In Situ Hybridization; Male; Paraventricular Hypothalamic Nucleus; Promoter Regions, Genetic; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Staurosporine; Stress, Physiological; Trans-Activators; Transcription Factors; Transcription, Genetic | 2012 |
Swelling rather than shrinkage precedes apoptosis in serum-deprived vascular smooth muscle cells.
Topics: Animals; Apoptosis; Caspase 3; Cell Size; Cells, Cultured; Chromatin; Colforsin; Culture Media, Serum-Free; DNA Cleavage; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osmotic Pressure; Ouabain; Rats; Single-Cell Analysis; Staurosporine; Time-Lapse Imaging | 2012 |