Compounds > staurosporine
Page last updated: 2024-08-23

staurosporine and chelerythrine

staurosporine has been researched along with chelerythrine in 97 studies

Research

Studies (97)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's52 (53.61)18.2507
2000's36 (37.11)29.6817
2010's9 (9.28)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1
Augereau, JM; Gleye, J; Herbert, JM; Maffrand, JP1
Grant, S; Jarvis, WD; Povirk, LF; Traylor, RS; Turner, AJ1
Amon, U; Herbert, JM; von Stebut, E; Wolff, HH1
Harrison, DG; Ohara, Y; Sayegh, HS; Yamin, JJ1
Houslay, MD; Savage, A; Zeng, L1
Guillemain, I; Rossignol, B1
Gunther, KE; Lydan, MA; O'Day, DH; Ramkissoon, S1
Dooley, NP; Noble, PG; Yong, VW1
Vietor, I; Vilcek, J1
Bennett, PB; Deal, KK; Fahrig, SA; Hu, NN; Murray, KT; Po, SS; Snyders, DJ; Tamkun, MM1
Dol, F; Dumas, A; Herbert, JM; Laplace, MC; Savi, P1
Terranova, PF; Zachow, RJ1
Ison, AJ; Johnson, MS; MacEwan, DJ; Mitchell, R; Thomson, FJ; Wolbers, WB1
Alvarez, J; Garcia-Sancho, J; Montero, M1
Rossignol, B; Sergheraert, C; Zoukhri, D1
Chabot-Fletcher, M; Foley, JJ; Sarau, HM; Torphy, TJ; Tzimas, MN; Winkler, JD; Zhou, HL1
Berton, G; Chieco-Bianchi, L; Saggioro, D; Sorio, C1
Maurer, JA; McKay, DB; Wenger, BW1
Berrie, CP; Cobbold, PH1
Chalfant, ML; Civan, JM; Civan, MM; DiBona, DR; O'Brien, TG; Peterson-Yantorno, K1
Arendshorst, WJ; Ruan, X1
Graham, A; Wood, JL1
Jordan, NJ; Watson, ML; Westwick, J; Yoshimura, T1
Lombardini, JB; Props, C1
Carrera, A; Gerton, GL; Kopf, GS; Moos, J; Moss, SB; Ning, XP; Tesarik, J1
Ducibella, T; LeFevre, L1
Chakravarthy, B; Durkin, JP; Mealing, G; Morley, P; Small, D; Song, D; Tremblay, R1
Atkins, KB; Simpson, RU; Somerman, MJ1
Aballay, A; Arenas, NG; Mayorga, LS; Quest, AF1
Armstrong, SC; Ganote, CE; Hoover, DB; Shivell, LC1
Chen, C; Clarke, IJ; Wu, D1
Muller, D; Stoppini, L; Toni, N1
Bremerich, DH; Jones, KA; Lorenz, RR; Shumway, R; Warner, DO1
Church, DJ; Lang, U; Morabito, D; Rebsamen, MC; Vallotton, MB1
Friedrich, RW; Mercier, AJ; Molnar, GF; Schiebe, M1
Harnett, MM; Houslay, MD; Michie, AM; Rena, G1
Barnhart, DC; Mulholland, MW; Sarosi, GA; Zhang, W1
Andersen, GO; Enger, M; Osnes, JB; Skomedal, T; Thoresen, GH1
Auslender, M; Obejero-Paz, CA; Scarpa, A1
Ivey, CL; Roy, BJ; Townsley, MI1
Anand-Srivastava, MB; Palaparti, A1
Block, ER; De Li, Y; Giraldo, C; Han, W; Su, Y1
Dyer, D; McCloud, E; Moyer, MP; Ortiz, A; Rubin, S; Said, HM1
Hashimoto, T; Hojo, K; Kawamata, T; Maeda, K; Nakai, M; Tanaka, C; Taniguchi, T; Terashima, A1
Lan, L; Wong, NS1
Olbrich, A; Thiemermann, C; Zacharowski, K1
Breder, J; Jäger, T; Opitz, T; Reymann, KG; Sabelhaus, CF; Schröder, UH1
Bakker, EN; Kerkhof, CJ; Sipkema, P1
Choi, JS; Hahn, SJ; Jo, YH; Kim, MS; Rhie, DJ1
Coultrap, SJ; Machu, TK; Sun, H; Tenner, TE1
Baik, EJ; Jung, YS; Lee, SH; Moon, CH1
Bergman, M; Chentoufi, J; Gray, M; Honbo, NY; Karliner, JS; Piacentini, L1
Boyan, BD; Dean, DD; Schwartz, Z; Sylvia, VL1
Kobayashi, S; Kumagai, M; Makioka, A; Ohtomo, H; Takeuchi, T1
Gibelli, S; Lorini, M; Miadonna, A; Tedeschi, A1
Armstead, WM1
Bazzoni, G; Bontrager, AL; Chen, LB; Hemler, ME; Kraeft, SK; Stipp, CS; Zhang, XA1
Ivy, MT; Karim, MR; Mtshali, CM; Newkirk, RF; Townsel, JG1
Altura, BM; Altura, BT; Li, W; Zheng, T1
Drew, AE; Werling, LL1
Beales, IL; Calam, J1
Morisco, C; Sadoshima, J; Seta, K; Vatner, SF; Yamamoto, S1
Hasmann, M; Hiddemann, W; Nuessler, V; Pelka-Fleischer, R; Pogrebniak, A; Stoetzer, OJ1
Benardo, LS; Blace, N; Crary, JF; Kelly, MT; Ling, DS; Sacktor, TC; Serrano, PA1
Maeta, H; Mizoguchi, K; Oe, M; Suzuki, T; Wang, YP; Yamashita, Y1
Andrews, DA; Low, PS; Yang, L1
Guimarães, S; Mota, A1
Trachte, GJ1
Bernhardt, R; Bureik, M; Zeeh, A1
Buss, AD; Butler, MS; Chan, SL; Flotow, H; Fu, NY; Lee, AS; Lee, MC; Soejarto, DD; Tan, KO; Yang, LK; Yu, VC1
Bacon, BR; Britton, RS; Li, L; O'Neill, R; Ramm, GA1
Cao, C; Cho, KW; Han, JH; Kim, SH; Kim, SZ1
Fabbro, M; Nair, SV; Raftos, DA1
Pavlova, OO; Sahach, VF; Solovĭov, AI1
Csiszar, A; Kaminski, PM; Koller, A; Ungvari, Z; Wolin, MS1
Akhter, SA; Bodi, I; Koch, SE; Petrashevskaya, NN; Schwartz, A1
Andreka, P; Bishopric, NH; Evans, WH; Haywood, GA; Martin, PE; Turner, MS; Webster, KA; You, L1
Gaivin, RJ; McCune, DF; Papay, RS; Perez, DM; Rorabaugh, BR; Ross, SA; Simpson, PC1
Chang, RL; Conney, AH; Hansson, A; Huberman, E; Klemons, S; Lin, Y; Patel, N; Ryan, A; Shih, WJ; Zheng, X1
Bae, YM; Earm, YE; Han, J; Kim, N; Ko, JH; Park, WS; Son, YK1
Alier, KA; Morris, BJ1
Bloehs, R; Borst, MM; Karle, CA; Kathöfer, S; Katus, HA; Kiehn, J; Kiesecker, C; Kreye, VA; Lueck, S; Pirot, M; Scherer, D; Schoels, W; Scholz, EP; Thomas, D; Zitron, E1
Do, SH; Kim, JH; Kim, YL; Zuo, Z1
Do, SH; Kim, HK; Kim, JH; Lim, YJ; Yun, JY; Zuo, Z1
Bernardi, P; Cabrelle, A; Cesura, AM; Colonna, R; Costantini, P; Gambalunga, A; Milanesi, E; Petronilli, V; Pinard, E; Semenzato, G1
Clark, OH; Duh, QY; Herfarth, C; Hoelting, T1
Lucas, P; Marion-Poll, F; Meunier, N1
Agalakova, NI; Gusev, GP1
Aguiar, JF; Costa, RR; Reis, RI; Varanda, WA1
Malinow, R; Nabavi, S; Newton, AC; Schramm, CL; Wu-Zhang, AX1
Chung, DI; Hong, Y; Kong, HH; Moon, EK1
Acharya, A; Kumar, S; Tomar, MS1
Casanelles, E; Garcia-Belinchón, M; Granados-Colomina, C; Iglesias-Guimarais, V; Martínez-Escardó, L; Pascual-Guiral, S; Ribas, J; Sánchez-Osuna, M; Yuste, VJ1
Almasry, M; Faggio, C; Jemaà, M; Lang, F; Mischitelli, M1
Al Mamun Bhuyan, A; Cao, H; Lang, F1

Other Studies

97 other study(ies) available for staurosporine and chelerythrine

ArticleYear
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013
Chelerythrine is a potent and specific inhibitor of protein kinase C.
    Biochemical and biophysical research communications, 1990, Nov-15, Volume: 172, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibiotics, Antineoplastic; Benzophenanthridines; Binding, Competitive; Brain; Cell Transformation, Neoplastic; Isoquinolines; Kinetics; Leukemia L1210; Lymphoma; Phenanthridines; Piperazines; Protein Kinase C; Rats; Staurosporine; Tumor Cells, Cultured

1990
Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C.
    Cancer research, 1994, Apr-01, Volume: 54, Issue:7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Anthracenes; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Cell Differentiation; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA Damage; DNA, Neoplasm; Enzyme Inhibitors; Gossypol; Humans; Isoquinolines; Leukemia, Promyelocytic, Acute; Naphthalenes; Perylene; Phenanthridines; Piperazines; Polycyclic Compounds; Protein Kinase C; Staurosporine; Time Factors; Tumor Cells, Cultured

1994
Investigations with the selective PKC inhibitor chelerythrine on human basophils.
    Agents and actions, 1994, Volume: 41 Spec No

    Topics: Alkaloids; Basophils; Benzophenanthridines; Calcimycin; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Phenanthridines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate

1994
Regulation of endothelial constitutive nitric oxide synthase by protein kinase C.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:3

    Topics: Alkaloids; Amino Acid Oxidoreductases; Animals; Benzophenanthridines; Cattle; Cells, Cultured; Endothelium, Vascular; Nitric Oxide Synthase; Phenanthridines; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate

1995
A role for protein kinase C-mediated phosphorylation in eliciting glucagon desensitization in rat hepatocytes.
    The Biochemical journal, 1995, Apr-01, Volume: 307 ( Pt 1)

    Topics: Adenylyl Cyclases; Alkaline Phosphatase; Alkaloids; Animals; Arginine Vasopressin; Benzophenanthridines; Cell Adhesion; Cells, Cultured; Collagen; Cyclic AMP; Drug Tolerance; Ethers, Cyclic; Glucagon; Liver; Male; Naphthalenes; Okadaic Acid; Phenanthridines; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine

1995
Protein kinase C and phospholipase D activation in rat parotid glands.
    FEBS letters, 1995, Apr-17, Volume: 363, Issue:1-2

    Topics: Alkaloids; Animals; Benzophenanthridines; Enzyme Activation; Glycerophospholipids; Male; Naphthalenes; Parotid Gland; Phenanthridines; Phosphatidic Acids; Phospholipase D; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate

1995
Fertilization in Dictyostelium: pharmacological analyses and the presence of a substrate protein suggest protein kinase C is essential for gamete fusion.
    Experimental cell research, 1995, Volume: 220, Issue:2

    Topics: Alkaloids; Animals; Benzophenanthridines; Dictyostelium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fertilization; Indoles; Kinetics; Maleimides; Membrane Fusion; Phenanthridines; Phosphoproteins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors

1995
Protein kinase C in cultured adult human oligodendrocytes: a potential role for isoform alpha as a mediator of process outgrowth.
    Journal of neuroscience research, 1994, Sep-01, Volume: 39, Issue:1

    Topics: Adult; Alkaloids; Animals; Base Sequence; Benzophenanthridines; Brain; Cells, Cultured; Diterpenes; Female; Humans; Isoenzymes; Molecular Sequence Data; Myelin Sheath; Nerve Tissue Proteins; Oligodendroglia; Phenanthridines; Phorbol Esters; Protein Kinase C; Rats; Rats, Wistar; Staurosporine

1994
Pathways of heat shock protein 28 phosphorylation by TNF in human fibroblasts.
    Lymphokine and cytokine research, 1994, Volume: 13, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Arsenites; Benzophenanthridines; Cell Line; Fibroblasts; Heat-Shock Proteins; Humans; Interleukin-1; Isoquinolines; Phenanthridines; Phosphorylation; Phosphotransferases; Piperazines; Sodium Compounds; Staurosporine; Tumor Necrosis Factor-alpha; Tyrosine

1994
Modulation of an inactivating human cardiac K+ channel by protein kinase C.
    Circulation research, 1994, Volume: 75, Issue:6

    Topics: Action Potentials; Alkaloids; Animals; Benzophenanthridines; Cell Membrane; Cloning, Molecular; Enzyme Activation; Heart; Humans; Myocardium; Oocytes; Phenanthridines; Phenotype; Phorbol Esters; Phosphorylation; Potassium Channels; Protein Kinase C; Staurosporine; Time Factors; Transfection; Xenopus

1994
Chelerythrine, a selective protein kinase C inhibitor, counteracts pyrogen-induced expression of tissue factor without effect on thrombomodulin down-regulation in endothelial cells.
    Thrombosis research, 1993, Sep-15, Volume: 71, Issue:6

    Topics: Alkaloids; Animals; Aorta; Benzophenanthridines; Cattle; Endothelium, Vascular; Endotoxins; Interleukin-1; Phenanthridines; Protein Kinase C; Pyrogens; Staurosporine; Thrombomodulin; Thromboplastin; Tumor Necrosis Factor-alpha

1993
Involvement of protein kinase C and protein tyrosine kinase pathways in tumor necrosis factor-alpha-induced clustering of ovarian theca-interstitial cells.
    Molecular and cellular endocrinology, 1993, Volume: 97, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Androstenedione; Animals; Benzophenanthridines; Benzylidene Compounds; Catechols; Cell Adhesion; Diglycerides; Enzyme Activation; Female; Hypophysectomy; Isoquinolines; Luteinizing Hormone; Nitriles; Phenanthridines; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Theca Cells; Tumor Necrosis Factor-alpha; Tyrphostins

1993
The differential effects of protein kinase C activators and inhibitors on rat anterior pituitary hormone release.
    Molecular and cellular endocrinology, 1993, Volume: 94, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Anti-Bacterial Agents; Benzophenanthridines; Carcinogens; Cerebral Cortex; Cytosol; Diterpenes; Female; Growth Hormone; Indoles; Isomerism; Isoquinolines; Lung; Luteinizing Hormone; Maleimides; Phenanthridines; Phorbol 12,13-Dibutyrate; Piperazines; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Terpenes; Tritium

1993
Inhibition of the calcium store-operated calcium entry pathway by chemotactic peptide and by phorbol ester develops gradually and independently along differentiation of HL60 cells.
    The Journal of biological chemistry, 1993, Dec-25, Volume: 268, Issue:36

    Topics: Alkaloids; Benzophenanthridines; Biological Transport; Calcium; Cell Differentiation; Humans; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Staurosporine; Tumor Cells, Cultured

1993
Phorbol ester-stimulated exocytosis in lacrimal gland: PKC might not be the sole effector.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: Alkaloids; Animals; Benzophenanthridines; Bucladesine; Diglycerides; Exocytosis; In Vitro Techniques; Lacrimal Apparatus; Male; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Trifluoperazine

1993
Association between leukotriene B4-induced phospholipase D activation and degranulation of human neutrophils.
    Biochemical pharmacology, 1993, Jul-06, Volume: 46, Issue:1

    Topics: Alkaloids; Benzophenanthridines; Calcium; Cell Degranulation; Cytochalasin B; Dose-Response Relationship, Drug; Enzyme Activation; Ethanol; Humans; Leukotriene B4; Neutrophils; Phenanthridines; Phospholipase D; Propranolol; Protein Kinase C; Staurosporine

1993
The monosialoganglioside GM1 induces internalisation and degradation of the CD4 antigen in U937 cells: evidence for a novel mechanism of CD4 down-modulation in a p56lck-negative cell line, which is independent of protein kinase C activation.
    Biochemical and biophysical research communications, 1993, Mar-31, Volume: 191, Issue:3

    Topics: Alkaloids; Benzophenanthridines; CD4 Antigens; Down-Regulation; Endocytosis; Enzyme Activation; G(M1) Ganglioside; Humans; In Vitro Techniques; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phenanthridines; Protein Kinase C; Proto-Oncogene Proteins; Staurosporine; Tumor Cells, Cultured

1993
Effects of protein kinase inhibitors on morphology and function of cultured bovine adrenal chromaffin cells: KN-62 inhibits secretory function by blocking stimulated Ca2+ entry.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Medulla; Alkaloids; Animals; Benzophenanthridines; Biological Transport; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Catecholamines; Cattle; Cells, Cultured; Enzyme Inhibitors; Indole Alkaloids; Isoquinolines; Phenanthridines; Piperazines; Protein Kinase C; Staurosporine; Substrate Specificity

1996
Both activators and inhibitors of protein kinase C promote the inhibition of phenylephrine-induced [Ca2+]i oscillations in single intact rat hepatocytes.
    Cell calcium, 1995, Volume: 18, Issue:3

    Topics: Alkaloids; Amino Acid Sequence; Animals; Benzophenanthridines; Calcium; Enzyme Activation; Enzyme Inhibitors; Indoles; Liver; Male; Maleimides; Molecular Sequence Data; Oligopeptides; Phenanthridines; Phenylephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Staurosporine

1995
Regulation of epithelial Na+ permeability by protein kinase C is tissue specific.
    The Journal of membrane biology, 1996, Volume: 152, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldosterone; Alkaloids; Amiloride; Animals; Benzophenanthridines; Biological Transport; Bufo marinus; Enzyme Inhibitors; Epithelium; In Vitro Techniques; Isoquinolines; Kinetics; Membrane Potentials; Organ Specificity; Phenanthridines; Piperazines; Protein Kinase C; Rana catesbeiana; Rana pipiens; Skin; Skin Physiological Phenomena; Sodium; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Urinary Bladder

1996
Role of protein kinase C in angiotensin II-induced renal vasoconstriction in genetically hypertensive rats.
    The American journal of physiology, 1996, Volume: 270, Issue:6 Pt 2

    Topics: Alkaloids; Angiotensin II; Animals; Antihypertensive Agents; Benzophenanthridines; Biphenyl Compounds; Hemodynamics; Hypertension; Imidazoles; Losartan; Phenanthridines; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renal Circulation; Staurosporine; Tetrazoles; Vasoconstrictor Agents

1996
Induction of thiol recycling by protein kinase C: a potentially pro-oxidant pathway for low-density lipoprotein oxidation.
    Biochemical Society transactions, 1996, Volume: 24, Issue:3

    Topics: Alkaloids; Arteriosclerosis; Benzophenanthridines; Cell Line; Enzyme Inhibitors; Humans; Lipoproteins, LDL; Monocytes; Oxidants; Oxidation-Reduction; Phenanthridines; Protein Kinase C; Staurosporine; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate

1996
Differential effects of protein kinase C inhibitors on chemokine production in human synovial fibroblasts.
    British journal of pharmacology, 1996, Volume: 117, Issue:6

    Topics: Alkaloids; Benzophenanthridines; Blotting, Northern; Cells, Cultured; Fibroblasts; Humans; Indoles; Interleukin-1; Interleukin-8; Maleimides; Phenanthridines; Protein Kinase C; RNA, Messenger; Staurosporine; Synovial Membrane; Tumor Necrosis Factor-alpha

1996
Effects of kinase inhibitors and taurine analogues on the phosphorylation of specific proteins in mitochondrial fractions of rat heart and retina.
    Advances in experimental medicine and biology, 1996, Volume: 403

    Topics: Alkaloids; Animals; Benzophenanthridines; Enzyme Inhibitors; Kinetics; Mitochondria; Mitochondria, Heart; Molecular Weight; Phenanthridines; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proteins; Rats; Retina; Staurosporine; Taurine

1996
Regulation of protein tyrosine phosphorylation in human sperm by a calcium/calmodulin-dependent mechanism: identification of A kinase anchor proteins as major substrates for tyrosine phosphorylation.
    Developmental biology, 1996, Nov-25, Volume: 180, Issue:1

    Topics: Alkaloids; Animals; Benzophenanthridines; Calcimycin; Calcium; Calmodulin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Genistein; Humans; Isoflavones; Male; Mice; Phenanthridines; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Proteins; Seminal Plasma Proteins; Spermatozoa; Staurosporine

1996
Study of protein kinase C antagonists on cortical granule exocytosis and cell-cycle resumption in fertilized mouse eggs.
    Molecular reproduction and development, 1997, Volume: 46, Issue:2

    Topics: Alkaloids; Animals; Benzophenanthridines; Cell Cycle; Cell Degranulation; Enzyme Inhibitors; Exocytosis; Humans; Indoles; Male; Maleimides; Mice; Phenanthridines; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Zygote

1997
Evidence that the early loss of membrane protein kinase C is a necessary step in the excitatory amino acid-induced death of primary cortical neurons.
    Journal of neurochemistry, 1997, Volume: 68, Issue:4

    Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; Calcium; Carcinogens; Cell Death; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Fetus; Gene Expression; Glutamic Acid; Kainic Acid; Membrane Proteins; N-Methylaspartate; Naphthalenes; Neurons; Phenanthridines; Potassium Chloride; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Staurosporine; Tetradecanoylphorbol Acetate

1997
Stimulation of osteopontin mRNA expression in HL-60 cells is independent of differentiation.
    Archives of biochemistry and biophysics, 1997, Jul-15, Volume: 343, Issue:2

    Topics: Alkaloids; Benzophenanthridines; Butyrates; Butyric Acid; Calcitriol; Cell Adhesion; Cell Adhesion Molecules; Cell Differentiation; Cycloheximide; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Mitogen-Activated Protein Kinase Kinases; Osteopontin; Phenanthridines; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase Inhibitors; Recombinant Proteins; RNA, Messenger; Sialoglycoproteins; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tretinoin

1997
A factor with a zinc- and phorbol ester-binding domain is necessary for endosome fusion.
    Experimental cell research, 1997, Aug-25, Volume: 235, Issue:1

    Topics: Alkaloids; Animals; Benzophenanthridines; Binding Sites; Cell Line; Cysteine; Endosomes; Enzyme Inhibitors; Isoenzymes; Kinetics; Macrophages; Membrane Fusion; Naphthalenes; Peptide Fragments; Phenanthridines; Protein Kinase C; Recombinant Fusion Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Zinc

1997
Preconditioning of isolated rabbit cardiomyocytes: no evident separation of induction, memory and protection.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:8

    Topics: Adenosine; Alkaloids; Animals; Benzophenanthridines; Cardiovascular Agents; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Heart; Ischemic Preconditioning, Myocardial; Myocardial Ischemia; Myocardium; Naphthalenes; Phenanthridines; Protein Kinase C; Rabbits; Staurosporine

1997
The role of protein kinase C in GH secretion induced by GH-releasing factor and GH-releasing peptides in cultured ovine somatotrophs.
    The Journal of endocrinology, 1997, Volume: 154, Issue:2

    Topics: Alkaloids; Animals; Benzophenanthridines; Carcinogens; Cell Membrane; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Growth Hormone; Growth Hormone-Releasing Hormone; Isoquinolines; Naphthalenes; Oligopeptides; Phenanthridines; Pituitary Gland; Protein Kinase C; Second Messenger Systems; Sheep; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors

1997
Staurosporine but not chelerythrine inhibits regeneration in hippocampal organotypic cultures.
    Synapse (New York, N.Y.), 1997, Volume: 27, Issue:3

    Topics: Alkaloids; Animals; Animals, Newborn; Benzophenanthridines; Electrophysiology; Enzyme Inhibitors; Hippocampus; Immunohistochemistry; Long-Term Potentiation; Nerve Fibers; Nerve Regeneration; Neurites; Neuronal Plasticity; Organ Culture Techniques; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Staurosporine

1997
Role of protein kinase C in calcium sensitization during muscarinic stimulation in airway smooth muscle.
    The American journal of physiology, 1997, Volume: 273, Issue:4

    Topics: Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Calcium; Cell Membrane Permeability; Cytosol; Diglycerides; Dogs; Enzyme Inhibitors; Escin; Female; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Naphthalenes; Peptide Fragments; Phenanthridines; Protein Kinase C; Receptors, Muscarinic; Staurosporine; Trachea

1997
Role of cAMP and calcium influx in endothelin-1-induced ANP release in rat cardiomyocytes.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Alkaloids; Animals; Animals, Newborn; Atrial Natriuretic Factor; Benzophenanthridines; Calcium; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Egtazic Acid; Endothelin-1; Enzyme Inhibitors; Epoprostenol; Heart; Heart Ventricles; Kinetics; Myocardium; Naphthalenes; Nifedipine; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Staurosporine; Thionucleotides

1997
Protein kinase C is required for long-lasting synaptic enhancement by the neuropeptide DRNFLRFamide in crayfish.
    Journal of neurophysiology, 1998, Volume: 79, Issue:2

    Topics: Alkaloids; Animals; Astacoidea; Benzophenanthridines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; FMRFamide; Indoles; Maleimides; Neuronal Plasticity; Phenanthridines; Protein Kinase C; Staurosporine; Synaptic Transmission; Tetradecanoylphorbol Acetate

1998
Upregulation of cAMP-specific PDE-4 activity following ligation of the TCR complex on thymocytes is blocked by selective inhibitors of protein kinase C and tyrosyl kinases.
    Cell biochemistry and biophysics, 1998, Volume: 28, Issue:2-3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Alkaloids; Animals; Benzophenanthridines; CD3 Complex; Cells, Cultured; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cycloheximide; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Mice; Mice, Inbred BALB C; Nucleic Acid Synthesis Inhibitors; Phenanthridines; Protein Kinase C; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thymus Gland; Up-Regulation

1998
Endothelin-stimulated capacitative calcium entry in enteric glial cells: synergistic effects of protein kinase C activity and nitric oxide.
    Journal of neurochemistry, 1998, Volume: 71, Issue:1

    Topics: Alkaloids; Animals; Benzophenanthridines; Calcium; Calcium Channels; Carcinogens; Cells, Cultured; Drug Synergism; Endothelin-3; Enzyme Inhibitors; Guinea Pigs; Myenteric Plexus; Neuroglia; Nickel; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Penicillamine; Phenanthridines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate

1998
Alpha1-adrenergic activation of myocardial Na-K-2Cl cotransport involving mitogen-activated protein kinase.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: 4-Aminopyridine; Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-Antagonists; Alkaloids; Animals; Benzophenanthridines; Bumetanide; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Enzyme Inhibitors; Flavonoids; In Vitro Techniques; Kinetics; Male; Myocardium; Phenanthridines; Phenylephrine; Potassium Channels; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters; Staurosporine; Timolol

1998
PKC activity modulates availability and long openings of L-type Ca2+ channels in A7r5 cells.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Alkaloids; Animals; Aorta; Benzophenanthridines; Calcium Channels; Calcium Channels, L-Type; Cell Line; Enzyme Activation; Enzyme Inhibitors; Ion Channel Gating; Kinetics; Membrane Potentials; Muscle, Smooth, Vascular; Okadaic Acid; Patch-Clamp Techniques; Phenanthridines; Phorbol 12,13-Dibutyrate; Probability; Protein Kinase C; Rats; Staurosporine

1998
Ablation of lung endothelial injury after pacing-induced heart failure is related to alterations in Ca2+ signaling.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Alkaloids; Angiotensin II; Animals; Benzophenanthridines; Calcimycin; Calcium; Capillary Permeability; Cardiac Output, Low; Cardiac Pacing, Artificial; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Ionophores; Lung; Phenanthridines; Protein Kinase C; Signal Transduction; Staurosporine; Thapsigargin; Vascular Resistance

1998
Angiotensin II modulates ANP-R2/ANP-C receptor-mediated inhibition of adenylyl cyclase in vascular smooth muscle cells: role of protein kinase C.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:8

    Topics: Adenylyl Cyclase Inhibitors; Alkaloids; Angiotensin II; Animals; Benzophenanthridines; Cells, Cultured; Down-Regulation; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanylate Cyclase; Muscle, Smooth, Vascular; Phenanthridines; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins; Rats; Receptors, Atrial Natriuretic Factor; Staurosporine

1998
Effect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cells.
    American journal of respiratory cell and molecular biology, 1998, Volume: 19, Issue:5

    Topics: Alkaloids; Animals; Antioxidants; Benzophenanthridines; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; L-Lactate Dehydrogenase; Nicotiana; Nicotine; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenanthridines; Plants, Toxic; Pulmonary Artery; RNA, Messenger; Smoking; Staurosporine; Swine; Time Factors

1998
Biotin uptake by human colonic epithelial NCM460 cells: a carrier-mediated process shared with pantothenic acid.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: Alkaloids; Benzophenanthridines; Biological Transport; Biotin; Cell Line; Colon; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Humans; Intestinal Absorption; Intestinal Mucosa; Kinetics; Pantothenic Acid; Phenanthridines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate

1998
PKC and tyrosine kinase involvement in amyloid beta (25-35)-induced chemotaxis of microglia.
    Neuroreport, 1998, Oct-26, Volume: 9, Issue:15

    Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzophenanthridines; Benzoquinones; Brain; Carcinogens; Cells, Cultured; Chemotaxis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Lactams, Macrocyclic; Microglia; Naphthalenes; Peptide Fragments; Phenanthridines; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Wistar; Rifabutin; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate

1998
Phosphatidylinositol 3-kinase and protein kinase C are required for the inhibition of caspase activity by epidermal growth factor.
    FEBS letters, 1999, Feb-05, Volume: 444, Issue:1

    Topics: Alkaloids; Androstadienes; Apoptosis; Benzophenanthridines; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Chromatin; Chromones; DNA Fragmentation; Enzyme Precursors; Epidermal Growth Factor; Flow Cytometry; Humans; Indoles; Maleimides; Molecular Weight; Morpholines; Phenanthridines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin

1999
Reduction of myocardial injury by the EP3 receptor agonist TEI-3356. Role of protein kinase C and of K(ATP)-channels.
    European journal of pharmacology, 1999, Feb-12, Volume: 367, Issue:1

    Topics: Adenosine Triphosphate; Alkaloids; Animals; Anti-Arrhythmia Agents; Benzophenanthridines; Decanoic Acids; Enzyme Inhibitors; Epoprostenol; Hemodynamics; Hydroxy Acids; Male; Myocardial Infarction; Myocardial Reperfusion; Phenanthridines; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Staurosporine

1999
Protective effect of group I metabotropic glutamate receptor activation against hypoxic/hypoglycemic injury in rat hippocampal slices: timing and involvement of protein kinase C.
    Neuropharmacology, 1999, Volume: 38, Issue:2

    Topics: Alkaloids; Animals; Benzophenanthridines; Cell Hypoxia; Enzyme Inhibitors; Evoked Potentials; Hippocampus; Hypoglycemia; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Neurons; Neuroprotective Agents; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Staurosporine; Time Factors

1999
Signal transduction in spontaneous myogenic tone in isolated arterioles from rat skeletal muscle.
    Cardiovascular research, 1999, Volume: 41, Issue:1

    Topics: Adrenergic alpha-Agonists; Alkaloids; Animals; Arterioles; Benzophenanthridines; Carbamates; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Unsaturated; Gadolinium; In Vitro Techniques; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Naphthalenes; Phenanthridines; Phenylcarbamates; Phenylephrine; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Type C Phospholipases; Vasoconstriction

1999
Staurosporine directly blocks Kv1.3 channels expressed in Chinese hamster ovary cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:4

    Topics: Alkaloids; Animals; Benzophenanthridines; CHO Cells; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Gene Expression Regulation; Kv1.3 Potassium Channel; Membrane Potentials; Patch-Clamp Techniques; Phenanthridines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase C; Staurosporine; Thionucleotides

1999
Competitive antagonism of the mouse 5-hydroxytryptamine3 receptor by bisindolylmaleimide I, a "selective" protein kinase C inhibitor.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:1

    Topics: Alkaloids; Animals; Benzophenanthridines; Binding, Competitive; Cell Membrane; DNA; Enzyme Inhibitors; In Vitro Techniques; Indoles; Maleimides; Mice; Naphthalenes; Oocytes; Patch-Clamp Techniques; Phenanthridines; Protein Kinase C; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; RNA; Serotonin Antagonists; Staurosporine; Xenopus laevis

1999
Protein kinase C inhibitors abolish the increased resistance of diabetic rat heart to ischemia-reperfusion injury.
    The Japanese journal of physiology, 1999, Volume: 49, Issue:5

    Topics: Alkaloids; Animals; Benzophenanthridines; Blood Pressure; Coronary Circulation; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Enzyme Inhibitors; Heart Rate; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Phenanthridines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine

1999
Endothelin-1 stimulates cardiac fibroblast proliferation through activation of protein kinase C.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:4

    Topics: Alkaloids; Animals; Benzophenanthridines; Cell Division; Cells, Cultured; DNA; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Interleukin-1; Isoenzymes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Myocardium; Phenanthridines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate

2000
Transforming growth factor-beta1 regulation of resting zone chondrocytes is mediated by two separate but interacting pathways.
    Biochimica et biophysica acta, 2000, Apr-17, Volume: 1496, Issue:2-3

    Topics: Alkaline Phosphatase; Alkaloids; Animals; Arachidonic Acid; Benzophenanthridines; Cell Division; Cell Membrane; Chondrocytes; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Male; Phenanthridines; Phospholipases A; Protein Kinase C; Proteoglycans; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Transforming Growth Factor beta

2000
Entamoeba invadens: protein kinase C inhibitors block the growth and encystation.
    Experimental parasitology, 2000, Volume: 95, Issue:4

    Topics: Alkaloids; Animals; Benzophenanthridines; Entamoeba; Enzyme Inhibitors; Naphthalenes; Phenanthridines; Protein Kinase C; Signal Transduction; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate

2000
Effects of protein kinase C and phospholipase C inhibitors on IgE-dependent and IgE-independent basophil histamine release.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2000, Volume: 49, Issue:9

    Topics: Alkaloids; Basophils; Benzophenanthridines; Enzyme Inhibitors; Estrenes; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine Release; Humans; Immunoglobulin E; Interleukin-3; N-Formylmethionine Leucyl-Phenylalanine; Phenanthridines; Protein Kinase C; Pyrrolidinones; Staurosporine; Type C Phospholipases

2000
NOC/oFQ PKC-dependent superoxide generation contributes to hypoxic-ischemic impairment of NMDA cerebrovasodilation.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:6

    Topics: Alkaloids; Animals; Animals, Newborn; Anions; Benzophenanthridines; Cerebral Arteries; Cerebrovascular Circulation; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Free Radicals; Hypoxia-Ischemia, Brain; Indicators and Reagents; Male; N-Methylaspartate; Nitroblue Tetrazolium; Nociceptin; Opioid Peptides; Peptide Fragments; Phenanthridines; Pia Mater; Protein Kinase C; Staurosporine; Superoxide Dismutase; Superoxides; Swine; Vasodilation; Vasodilator Agents

2000
Phosphorylation of a conserved integrin alpha 3 QPSXXE motif regulates signaling, motility, and cytoskeletal engagement.
    Molecular biology of the cell, 2001, Volume: 12, Issue:2

    Topics: Alkaloids; Amino Acid Motifs; Amino Acid Sequence; Animals; Antigens, CD; Benzophenanthridines; Cell Adhesion Molecules; Cell Movement; CHO Cells; Conserved Sequence; Cricetinae; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Enzyme Inhibitors; Genistein; Integrin alpha3; Integrins; Kalinin; Mass Spectrometry; Molecular Sequence Data; Mutagenesis; Phenanthridines; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Serine; Signal Transduction; Staurosporine

2001
Hemicholinium-3 mustard reveals two populations of cycling choline cotransporters in Limulus.
    Neuroscience, 2001, Volume: 102, Issue:4

    Topics: Alkaloids; Animals; Benzophenanthridines; Binding, Competitive; Biological Transport; Carcinogens; Carrier Proteins; Cell Membrane; Choline; Cholinergic Agents; Cholinergic Fibers; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Ganglia, Invertebrate; Hemicholinium 3; Horseshoe Crabs; Male; Membrane Transport Proteins; Phenanthridines; Potassium Chloride; Protein Kinase C; Sodium; Staurosporine; Tetradecanoylphorbol Acetate; Tritium

2001
Use of protein kinase C inhibitors results in rapid [Mg(2+)](i) mobilization in primary cultured rat aortic smooth muscle cells: are certain kinase C isoforms natural homeostatic regulators of cystolic free Mg(2+).
    European journal of pharmacology, 2001, Feb-16, Volume: 413, Issue:2-3

    Topics: Alkaloids; Animals; Aorta; Benzophenanthridines; Carbazoles; Cells, Cultured; Enzyme Inhibitors; Indoles; Magnesium; Maleimides; Muscle, Smooth, Vascular; Naphthalenes; Phenanthridines; Protein Isoforms; Protein Kinase C; Rats; Staurosporine

2001
Protein kinase C regulation of dopamine transporter initiated by nicotinic receptor activation in slices of rat prefrontal cortex.
    Journal of neurochemistry, 2001, Volume: 77, Issue:3

    Topics: Alkaloids; Amphetamine; Animals; Benzophenanthridines; Calcium; Calcium Channel Blockers; Carrier Proteins; Dopamine; Dopamine Plasma Membrane Transport Proteins; Egtazic Acid; Enzyme Inhibitors; Indoles; Male; Maleimides; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nicotine; omega-Conotoxin GVIA; Phenanthridines; Potassium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Second Messenger Systems; Sodium Channels; Staurosporine; Tetrodotoxin; Tritium; Veratridine

2001
Inhibition of carbachol stimulated acid secretion by interleukin 1beta in rabbit parietal cells requires protein kinase C.
    Gut, 2001, Volume: 48, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Carbachol; Carcinogens; Cell Communication; Cells, Cultured; Cholinergic Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Acid; Interleukin-1; Parietal Cells, Gastric; Phenanthridines; Protein Kinase C; Rabbits; Sphingomyelin Phosphodiesterase; Staurosporine; Tetradecanoylphorbol Acetate

2001
Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:10

    Topics: Acetylcysteine; Adenoviridae; Alkaloids; Animals; Animals, Newborn; Annexin A5; Antioxidants; Apoptosis; Benzophenanthridines; Caspases; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Genetic Vectors; Glutathione; Hydrogen Peroxide; Immunoblotting; In Situ Nick-End Labeling; Injections, Intravenous; Microscopy, Fluorescence; Myocardium; Necrosis; Phenanthridines; Protein Isoforms; Protein Kinase C; Rats; Rats, Wistar; Reactive Oxygen Species; Staurosporine; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors

2001
Modulation of apoptosis by mitochondrial uncouplers: apoptosis-delaying features despite intrinsic cytotoxicity.
    Biochemical pharmacology, 2002, Feb-01, Volume: 63, Issue:3

    Topics: Adenosine Triphosphate; Alkaloids; Amino Acid Chloromethyl Ketones; Apoptosis; Aurintricarboxylic Acid; Benzophenanthridines; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Drug Interactions; Enzyme Inhibitors; HL-60 Cells; Humans; Mitochondria; NAD; NADP; Phenanthridines; Staurosporine; Tumor Cells, Cultured; Uncoupling Agents

2002
Protein kinase Mzeta is necessary and sufficient for LTP maintenance.
    Nature neuroscience, 2002, Volume: 5, Issue:4

    Topics: Alkaloids; Animals; Benzophenanthridines; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Patch-Clamp Techniques; Phenanthridines; Protein Kinase C; Pyramidal Cells; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Staurosporine

2002
Intestinal ischemia preconditions myocardium: role of protein kinase C and mitochondrial K(ATP) channel.
    Cardiovascular research, 2002, Aug-15, Volume: 55, Issue:3

    Topics: Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Blood Pressure; Decanoic Acids; Enzyme Inhibitors; Hydroxy Acids; Intestines; Ischemic Preconditioning; Ischemic Preconditioning, Myocardial; Male; Mitochondria, Heart; Models, Animal; Myocardial Ischemia; Phenanthridines; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Random Allocation; Rats; Rats, Sprague-Dawley; Staurosporine; Time Factors

2002
Phorbol ester stimulates a protein kinase C-mediated agatoxin-TK-sensitive calcium permeability pathway in human red blood cells.
    Blood, 2002, Nov-01, Volume: 100, Issue:9

    Topics: Adult; Agatoxins; Alkaloids; Benzophenanthridines; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Signaling; Cell Size; Diglycerides; Dimethyl Sulfoxide; Enzyme Inhibitors; Erythrocytes; Humans; Ion Transport; Ionophores; Marine Toxins; Okadaic Acid; Osmotic Fragility; Oxazoles; Phenanthridines; Phosphoprotein Phosphatases; Protein Kinase C; Spider Venoms; Staurosporine; Tetradecanoylphorbol Acetate

2002
Interaction between alpha2-autoreceptors and receptors mediating the effects of angiotensin II and bradykinin in the heart of newborn rats.
    European journal of pharmacology, 2002, Oct-25, Volume: 453, Issue:2-3

    Topics: Adrenergic alpha-Antagonists; Alkaloids; Angiotensin II; Animals; Animals, Newborn; Autoreceptors; Benzophenanthridines; Bradykinin; Colforsin; Electric Stimulation; In Vitro Techniques; Myocardium; Norepinephrine; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Bradykinin; Staurosporine; Yohimbine

2002
Natriuretic peptides suppress protein kinase C activity to reduce evoked dopamine efflux from pheochromocytoma (PC12) cells.
    Endocrinology, 2003, Volume: 144, Issue:1

    Topics: Alkaloids; Animals; Benzophenanthridines; Dopamine; Guanylate Cyclase; Natriuretic Peptide, C-Type; PC12 Cells; Phenanthridines; Protein Kinase C; Rats; Receptors, Atrial Natriuretic Factor; Staurosporine

2003
Modulation of steroid hydroxylase activity in stably transfected V79MZh11B1 and V79MZh11B2 cells by PKC and PKD inhibitors.
    Endocrine research, 2002, Volume: 28, Issue:4

    Topics: Acetophenones; Alkaloids; Benzophenanthridines; Benzopyrans; Carbazoles; Cell Line; Cortodoxone; Desoxycorticosterone; Enzyme Inhibitors; Hydroxylation; Indoles; Phenanthridines; Protein Kinase C; Staurosporine; Steroid Hydroxylases; Transfection

2002
Identification of chelerythrine as an inhibitor of BclXL function.
    The Journal of biological chemistry, 2003, Jun-06, Volume: 278, Issue:23

    Topics: Alkaloids; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Benzophenanthridines; Cytochrome c Group; Enzyme Inhibitors; Etoposide; Gene Expression; Humans; Membrane Proteins; Mitochondria; Molecular Mimicry; Nucleic Acid Synthesis Inhibitors; Phenanthridines; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Tumor Cells, Cultured

2003
Effect of protein kinase C activation and inhibition on rat hepatic stellate cell activation.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:4

    Topics: Actins; Alkaloids; Animals; Benzophenanthridines; Cell Division; Cells, Cultured; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; In Vitro Techniques; Indoles; Liver; Male; Maleimides; Phenanthridines; Phorbol Esters; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate

2003
Diverse regulation of atrial natriuretic peptide secretion by serotonin receptor subtypes.
    Cardiovascular research, 2003, Aug-01, Volume: 59, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Alkaloids; Aminobenzoates; Animals; Atrial Natriuretic Factor; Benzophenanthridines; Benzothiazoles; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Dose-Response Relationship, Drug; Heart; Heart Atria; Imines; Indoles; Isoquinolines; Ketanserin; Male; Myocytes, Cardiac; Neomycin; para-Aminobenzoates; Perfusion; Phenanthridines; Piperazines; Piperidines; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Staurosporine; Sulfonamides; Thiazoles; Type C Phospholipases

2003
Exocytosis of a complement component C3-like protein by tunicate hemocytes.
    Developmental and comparative immunology, 2004, Volume: 28, Issue:3

    Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Calcimycin; Carrageenan; Cell Survival; Cholera Toxin; Colchicine; Colforsin; Complement C3; Cytochalasin D; Cytoplasmic Vesicles; Enzyme-Linked Immunosorbent Assay; Exocytosis; Hemocytes; Immunohistochemistry; Kinetics; Lipopolysaccharides; Mannans; Microscopy, Electron; Phenanthridines; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Urochordata

2004
[Effect of inhibiting protein kinase C on calcium sensitivity of contractile apparatus of vascular smooth muscle during vasospasms of different origins].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2003, Volume: 49, Issue:6

    Topics: Actin Cytoskeleton; Alkaloids; Animals; Benzophenanthridines; Calcium; Cell Hypoxia; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenanthridines; Protein Kinase C; Pulmonary Artery; Radiation, Ionizing; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Staurosporine

2003
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.
    The American journal of pathology, 2004, Volume: 165, Issue:1

    Topics: Acetophenones; Acetylcholine; Alkaloids; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Benzophenanthridines; Captopril; Enzyme Inhibitors; Hypertension; Male; Models, Biological; NADPH Oxidases; Nitric Oxide Donors; Nitric Oxide Synthase; Onium Compounds; Organ Culture Techniques; Oxidative Stress; Penicillamine; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Renin-Angiotensin System; Staurosporine; Superoxide Dismutase; Vasoconstrictor Agents; Vasodilator Agents

2004
Effects of alpha1-adrenergic stimulation on normal and hypertrophied mouse hearts. Relation to caveolin-3 expression.
    Cardiovascular research, 2004, Aug-15, Volume: 63, Issue:3

    Topics: Action Potentials; Adrenergic alpha-Agonists; Alkaloids; Animals; Benzophenanthridines; Calcium Channels, L-Type; Cardiomegaly; Caveolin 3; Caveolins; Female; Immunoblotting; Male; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Perfusion; Phenanthridines; Phenylephrine; Protein Kinase C; Signal Transduction; Staurosporine; Stimulation, Chemical

2004
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
    Circulation research, 2004, Oct-01, Volume: 95, Issue:7

    Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate

2004
alpha1A- but not alpha1B-adrenergic receptors precondition the ischemic heart by a staurosporine-sensitive, chelerythrine-insensitive mechanism.
    Cardiovascular research, 2005, Feb-01, Volume: 65, Issue:2

    Topics: Alkaloids; Animals; Benzophenanthridines; Enzyme Inhibitors; Female; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Transgenic; Myocardial Contraction; Myocardial Ischemia; Myocardium; Perfusion; Phenanthridines; Protein Kinase C; Receptors, Adrenergic, alpha-1; Staurosporine

2005
Synergistic stimulatory effect of 12-O-tetradecanoylphorbol-13-acetate and capsaicin on macrophage differentiation in HL-60 and HL-525 human myeloid leukemia cells.
    International journal of oncology, 2005, Volume: 26, Issue:2

    Topics: Alkaloids; Antineoplastic Agents; Benzophenanthridines; Capsaicin; Carboxylesterase; Carcinogens; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia, Myeloid; Macrophages; Models, Chemical; Phenanthridines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors

2005
Staurosporine inhibits voltage-dependent K+ current through a PKC-independent mechanism in isolated coronary arterial smooth muscle cells.
    Journal of cardiovascular pharmacology, 2005, Volume: 45, Issue:3

    Topics: Algorithms; Alkaloids; Animals; Benzophenanthridines; Cell Separation; Coronary Vessels; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; In Vitro Techniques; Kinetics; Male; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Phenanthridines; Phosphorylation; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Kinase C; Rabbits; Staurosporine

2005
Divergent regulation of Pyk2/CAKbeta phosphorylation by Ca2+ and cAMP in the hippocampus.
    Biochimica et biophysica acta, 2005, Sep-30, Volume: 1745, Issue:3

    Topics: Alkaloids; Animals; Benzophenanthridines; Calcimycin; Calcium; Colforsin; Cyclic AMP; Focal Adhesion Kinase 2; Hippocampus; Immunoblotting; Immunoprecipitation; Long-Term Potentiation; Phenanthridines; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Staurosporine

2005
Regulation of cardiac inwardly rectifying potassium current IK1 and Kir2.x channels by endothelin-1.
    Journal of molecular medicine (Berlin, Germany), 2006, Volume: 84, Issue:1

    Topics: Aged; Alkaloids; Animals; Benzophenanthridines; Endothelin-1; Enzyme Inhibitors; Heart Atria; Humans; Middle Aged; Myocytes, Cardiac; Oocytes; Patch-Clamp Techniques; Potassium; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Protein Subunits; Receptor, Endothelin A; Staurosporine; Tachycardia; Xenopus laevis

2006
Effects of chronic exposure to ethanol on glutamate transporter EAAT3 expressed in Xenopus oocytes: evidence for protein kinase C involvement.
    Alcoholism, clinical and experimental research, 2005, Volume: 29, Issue:11

    Topics: Alkaloids; Animals; Benzophenanthridines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Phenanthridines; Protein Kinase C; RNA, Messenger; Staurosporine; Synaptic Transmission; Xenopus

2005
Effects of intravenous anesthetics on the activity of glutamate transporter EAAT3 expressed in Xenopus oocytes: evidence for protein kinase C involvement.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Alkaloids; Anesthetics, Intravenous; Animals; Benzophenanthridines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etomidate; Excitatory Amino Acid Transporter 3; Female; Glutamic Acid; Ketamine; Membrane Potentials; Oocytes; Phenanthridines; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Thiopental; Xenopus

2006
The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative.
    The Journal of biological chemistry, 2006, Apr-14, Volume: 281, Issue:15

    Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Barbiturates; bcl-2-Associated X Protein; Benzophenanthridines; Benzopyrans; Caspase 9; Caspases; Cell Line; Cell Line, Tumor; Cell Survival; Chlorambucil; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; HeLa Cells; Humans; Ligands; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Phenanthridines; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Rats; Rats, Wistar; RNA, Small Interfering; Staurosporine; Time Factors; Vidarabine

2006
Invasion of metastatic human follicular thyroid cancer is inhibited via antagonism of protein kinase C.
    Cancer letters, 1997, Oct-28, Volume: 119, Issue:1

    Topics: Benzophenanthridines; Cell Line, Tumor; Enzyme Inhibitors; Humans; Naphthalenes; Neoplasm Invasiveness; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Thyrotropin

1997
Water taste transduction pathway is calcium dependent in Drosophila.
    Chemical senses, 2009, Volume: 34, Issue:5

    Topics: Animals; Benzophenanthridines; Calcium; Calmodulin; Chloride Channels; Drosophila; Drosophila Proteins; Fluphenazine; Lanthanum; Osmolar Concentration; Protein Kinase C; Rats; Receptors, Cell Surface; Signal Transduction; Staurosporine; Sulfonamides

2009
Regulation of K-Cl cotransport in erythrocytes of frog Rana temporaria by commonly used protein kinase and protein phosphatase inhibitors.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2010, Volume: 180, Issue:3

    Topics: Animals; Benzophenanthridines; Biological Transport; Enzyme Inhibitors; Erythrocytes; Fluorides; Genistein; K Cl- Cotransporters; Okadaic Acid; Ouabain; Phosphoprotein Phosphatases; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quercetin; Rana temporaria; Staurosporine; Symporters; Tyrphostins

2010
Luteinizing hormone (LH) acts through PKA and PKC to modulate T-type calcium currents and intracellular calcium transients in mice Leydig cells.
    Cell calcium, 2011, Volume: 49, Issue:3

    Topics: Animals; Benzophenanthridines; Calcium; Calcium Channels, T-Type; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Electrophysiological Phenomena; Isoquinolines; Leydig Cells; Luteinizing Hormone; Male; Mice; Peptides; Protein Kinase C; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate

2011
Cellular pharmacology of protein kinase Mζ (PKMζ) contrasts with its in vitro profile: implications for PKMζ as a mediator of memory.
    The Journal of biological chemistry, 2012, Apr-13, Volume: 287, Issue:16

    Topics: Animals; Antineoplastic Agents; Benzophenanthridines; Chlorocebus aethiops; COS Cells; Enzyme Inhibitors; HEK293 Cells; HeLa Cells; Hippocampus; Humans; Memory; Neuronal Plasticity; Organ Culture Techniques; Peptides; Phosphorylation; Protein Kinase C; Rats; Staurosporine

2012
Protein kinase C signaling molecules regulate encystation of Acanthamoeba.
    Experimental parasitology, 2012, Volume: 132, Issue:4

    Topics: Acanthamoeba castellanii; Benzophenanthridines; Gene Silencing; Isoenzymes; Phylogeny; Protein Kinase C; Real-Time Polymerase Chain Reaction; Sequence Alignment; Sphingosine; Staurosporine

2012
Activation of p53-dependent/-independent pathways of apoptotic cell death by chelerythrine in a murine T cell lymphoma.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Blotting, Western; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; Female; Gene Expression Regulation, Neoplastic; Humans; Lymphoma, T-Cell; Male; Mice, Inbred BALB C; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Staurosporine; Tumor Suppressor Protein p53

2015
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.
    The Journal of biological chemistry, 2015, Aug-21, Volume: 290, Issue:34

    Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Carrier Proteins; Caspases; Cell Line, Tumor; Chromatin; Colchicine; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Microfilament Proteins; Necrosis; Neurons; Nocodazole; Peptidomimetics; Quinolines; Rotenone; Signal Transduction; Staurosporine; Thapsigargin

2015
Camalexin-Induced Cell Membrane Scrambling and Cell Shrinkage in Human Erythrocytes.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 41, Issue:2

    Topics: Benzophenanthridines; Calcium; Caspase Inhibitors; Cell Size; Ceramides; Cytosol; Eryptosis; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; Indoles; Oligopeptides; Phosphatidylserines; Reactive Oxygen Species; Staurosporine; Thiazoles

2017
Triggering of Eryptosis, the Suicidal Erythrocyte Death by Mammalian Target of Rapamycin (mTOR) inhibitor Temsirolimus.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 42, Issue:4

    Topics: Aniline Compounds; Annexin A5; Antineoplastic Agents; Benzamides; Benzophenanthridines; Calcium; Casein Kinase I; Caspases; Ceramides; Eryptosis; Erythrocytes; Fluoresceins; Gene Expression Regulation; Hemolysis; Humans; Imidazoles; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphatidylserines; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Reactive Oxygen Species; Signal Transduction; Sirolimus; Staurosporine; TOR Serine-Threonine Kinases; Xanthenes

2017