staurosporine has been researched along with calpain in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (21.88) | 18.2507 |
| 2000's | 16 (50.00) | 29.6817 |
| 2010's | 8 (25.00) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Allen, H; Gilbertsen, RB; Hajimohammadreza, I; Nath, R; Posner, A; Raser, KJ; Stafford, D; Talanian, RV; Wang, KK; Yuen, P | 1 |
| Galindo, MF; Jordán, J; Miller, RJ | 1 |
| Echevaria-Vázquez, D; Fagard, R; Lijnen, P; Petrov, V | 1 |
| Hayes, RL; Newcomb, JK; Pike, BR; Posmantur, RM; Wang, KK; Zhao, X | 1 |
| Gnegy, ME; McGinnis, KM; Wang, KK; Whitton, MM | 1 |
| Orrenius, S; Pörn-Ares, MI; Samali, A | 1 |
| Gnegy, ME; McGinnis, KM; Mukerjee, N; Park, YH; Wang, KK | 1 |
| Flood, DG; Lin, YG; Reaume, AG; Savage, MJ; Scott, RW; Siman, R; Trusko, S | 1 |
| Choi, WS; Chung, CW; Jin, BK; Jung, YK; Kim, SU; Lee, EH; Oh, TH; Oh, YJ; Saido, TC | 1 |
| Gilligan, DM; Sarid, R; Weese, J | 1 |
| Gada, H; Guttmann, RP; Neumar, RW; Siman, R; Xu, YA | 1 |
| Benjamins, JA; George, EB; Nedelkoska, L | 1 |
| Bantubungi, K; Blum, D; Brotchi, J; Brouillet, E; Chtarto, A; Déglon, N; Galas, MC; Greco, A; Jacquard, C; Levivier, M; Minghetti, L; Pintor, A; Popoli, P; Schiffmann, SN; Tai, K; Tenenbaum, L | 1 |
| Duckett, CS; Gélinas, C; Kucharczak, JF; Simmons, MJ | 1 |
| Jurewicz, A; Kilianek, L; Matysiak, M; Raine, CS; Selmaj, K; Tybor, K | 1 |
| De Veyra, T; Greer, PA; Tan, Y; Wu, C | 1 |
| Brunner, T; Perozzo, R; Scapozza, L; Schaffner, T; Schmid, I; Simon, HU; Yousefi, S; Ziemiecki, A | 1 |
| Kinsey, GR; Lock, EA; Reed, CJ; Schnellmann, RG | 1 |
| Beart, PM; Chen, B; Cheung, NS; Diwakarla, S; Lim, ML; Mercer, LD; Nagley, P | 1 |
| Choi, WS; Lee, E; Lim, J; Oh, YJ | 1 |
| Gogvadze, V; Horn, M; Norberg, E; Orrenius, S; Ott, M; Uhlén, P; Zhivotovsky, B | 1 |
| Beart, PM; Chen, B; Diwakarla, S; Hughes, ML; Nagley, P | 1 |
| Hayes, RL; Larner, SF; Liu, MC; Wang, KK; Zhang, Z; Zheng, W | 1 |
| Howe, J; Tan, KSW; Yin, J | 1 |
| Morán, J; Ortega, A | 1 |
| Karlsson, M; Korenovska, O; Norberg, E; Orrenius, S; Silberberg, G; Szydlowski, S; Uhlén, P; Zhivotovsky, B | 1 |
| Bampton, ET; Cohen, GM; Norman, JM | 1 |
| Arnould, T; Charlier, S; Malaisse, J; Michel, S; Renard, P; Rommelaere, G | 1 |
| Jantas, D; Lason, W; Piotrowski, M | 1 |
| Chwastek, J; Jantas, D; Lasoń, W | 1 |
| Johnson, C; Kobeissy, F; Kurup, M; Mouhawasse, E; Nguyen, L; Pafundi, N; Torres, I; Wang, KK; Yadikar, H; Yang, Z; Yost, R | 1 |
| Bassiouni, W; Schulz, R; Seubert, JM | 1 |
32 other study(ies) available for staurosporine and calpain
| Article | Year |
|---|---|
Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis.
Topics: Amino Acid Sequence; Animals; Apoptosis; Calpain; Caspase 1; Cell Line; Cells, Cultured; Cerebellum; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Kinetics; Marine Toxins; Molecular Sequence Data; Neuroblastoma; Neurons; Oxocins; PC12 Cells; Rats; Spectrin; Staurosporine; Substrate Specificity; Tumor Cells, Cultured | 1996 |
Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture.
Topics: Amyloid beta-Peptides; Animals; Calcium; Calpain; Caspase 1; Cell Death; Cells, Cultured; Cysteine Endopeptidases; DNA Fragmentation; Endopeptidases; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Interleukin-1; N-Methylaspartate; Neurotoxins; Peptide Fragments; Pregnancy; Pyramidal Cells; Rats; Staurosporine | 1997 |
Protein kinase C induced changes in erythrocyte Na+/H+ exchange and cytosolic free calcium in humans.
Topics: Calcium; Calpain; Carcinogens; Cytosol; Enzyme Inhibitors; Erythrocytes; Humans; Protein Kinase C; Sodium; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate | 1998 |
Temporal relationships between de novo protein synthesis, calpain and caspase 3-like protease activation, and DNA fragmentation during apoptosis in septo-hippocampal cultures.
Topics: Animals; Apoptosis; Calpain; Caspase 3; Caspases; Cells, Cultured; Cysteine Endopeptidases; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Hippocampus; Nerve Tissue Proteins; Neuroglia; Neurons; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Rats; Septum Pellucidum; Spectrin; Staurosporine; Time Factors | 1998 |
Calcium/calmodulin-dependent protein kinase IV is cleaved by caspase-3 and calpain in SH-SY5Y human neuroblastoma cells undergoing apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Aspartic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Calpain; Caspase 3; Caspases; Chlorobenzoates; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Mice; Neuroblastoma; Peptide Fragments; Recombinant Proteins; Staurosporine; Thapsigargin; Tumor Cells, Cultured | 1998 |
Cleavage of the calpain inhibitor, calpastatin, during apoptosis.
Topics: Acetylcysteine; Apoptosis; Calcium-Binding Proteins; Calpain; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; fas Receptor; Flow Cytometry; Humans; Jurkat Cells; Pepstatins; Protease Inhibitors; Staurosporine; Tumor Necrosis Factor-alpha; U937 Cells | 1998 |
Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates.
Topics: Acetylcysteine; Aspartic Acid; Calpain; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Precursors; Humans; Marine Toxins; Oxocins; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Staurosporine; Substrate Specificity | 1999 |
Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability.
Topics: Alzheimer Disease; Amino Acid Substitution; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apoptosis; Calpain; Caspases; Cell Survival; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Gene Targeting; Glutamic Acid; Homozygote; Membrane Proteins; Mice; Mice, Mutant Strains; Mice, Transgenic; Neurons; Peptide Fragments; Presenilin-1; Staurosporine | 2000 |
Cleavage of Bax is mediated by caspase-dependent or -independent calpain activation in dopaminergic neuronal cells: protective role of Bcl-2.
Topics: 1-Methyl-4-phenylpyridinium; Animals; bcl-2-Associated X Protein; Calpain; Caspases; Cell Death; Cell Line; Dopamine; Enzyme Inhibitors; Herbicides; Humans; Microscopy, Electron; Necrosis; Neurons; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine | 2001 |
Adducin in platelets: activation-induced phosphorylation by PKC and proteolysis by calpain.
Topics: Adult; Blood Platelets; Calmodulin-Binding Proteins; Calpain; Cytoskeletal Proteins; Dipeptides; Humans; In Vitro Techniques; Kinetics; Phosphorylation; Platelet Activation; Platelet Aggregation; Protein Kinase C; Recombinant Proteins; Regression Analysis; Staurosporine; Thrombin | 2002 |
Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis.
Topics: Apoptosis; Blotting, Western; Calcium-Binding Proteins; Calpain; Caspase 3; Caspases; Cell Line; Cell Membrane; Cell Nucleus; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Microscopy, Fluorescence; Necrosis; Neurons; Staurosporine; Time Factors; Transfection; Tumor Cells, Cultured; Up-Regulation | 2003 |
Protection of mature oligodendrocytes by inhibitors of caspases and calpains.
Topics: Amino Acid Chloromethyl Ketones; Animals; Calcium; Calpain; Caspase Inhibitors; Cell Death; Cells, Cultured; Cysteine Proteinase Inhibitors; Kainic Acid; Mice; Mice, Inbred BALB C; Oligodendroglia; Penicillamine; Staurosporine; Thapsigargin | 2003 |
Minocycline in phenotypic models of Huntington's disease.
Topics: Animals; Calpain; Caspases; Cell Death; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Glutamic Acid; Huntingtin Protein; Huntington Disease; Male; Minocycline; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Nitro Compounds; Nuclear Proteins; Phenotype; Propionates; Quinolinic Acid; Rats; Rats, Inbred Lew; Rats, Wistar; Staurosporine | 2005 |
Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor.
Topics: Amino Acid Sequence; Animals; Apoptosis; B-Lymphocytes; Calpain; Cell Death; Cell Line; Cycloheximide; Flow Cytometry; Green Fluorescent Proteins; Humans; Immunoprecipitation; Lysine; Mice; Minor Histocompatibility Antigens; Models, Biological; Molecular Sequence Data; Mutagenesis; Mutation; Phenotype; Plasmids; Proteasome Endopeptidase Complex; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Receptors, Tumor Necrosis Factor; Sequence Homology, Amino Acid; Staurosporine; Transfection; Ubiquitin | 2005 |
Tumour necrosis factor-induced death of adult human oligodendrocytes is mediated by apoptosis inducing factor.
Topics: Adult; Animals; Apoptosis; Apoptosis Inducing Factor; Calpain; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspases; Cathepsins; Cell Death; Cell Line; DNA Fragmentation; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Mice; Mitochondrial Membranes; Oligodendroglia; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Serine Endopeptidases; Staurosporine; Translocation, Genetic; Tumor Necrosis Factors | 2005 |
Ubiquitous calpains promote both apoptosis and survival signals in response to different cell death stimuli.
Topics: Animals; Apoptosis; Calpain; Cell Survival; Cells, Cultured; Cytochromes c; Enzyme Inhibitors; Fibroblasts; Lysosomes; Mice; Mice, Mutant Strains; Mitochondria; Phosphatidylinositol 3-Kinases; Phosphatidylserines; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Signal Transduction; Staurosporine; Tumor Suppressor Protein p53 | 2006 |
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Autophagy-Related Protein 5; Calpain; Caspases; Cytochromes c; Cytosol; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Etoposide; Granulocyte-Macrophage Colony-Stimulating Factor; HeLa Cells; Humans; Microtubule-Associated Proteins; Mitochondria; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Staurosporine | 2006 |
Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells.
Topics: Amino Acid Chloromethyl Ketones; Aniline Compounds; Antimetabolites, Antineoplastic; Apoptosis; Benzoic Acid; Benzylidene Compounds; Calpain; Caspases; Cathepsin B; Cathepsin D; Cell Line, Tumor; Cell Size; Ceramides; Cisplatin; Exocytosis; Fumonisins; Humans; Kidney Neoplasms; Naphthalenes; Niflumic Acid; Nitrobenzoates; Phosphatidylserines; Pyrones; Sphingomyelin Phosphodiesterase; Staurosporine; Triterpenes | 2007 |
Hierarchical recruitment by AMPA but not staurosporine of pro-apoptotic mitochondrial signaling in cultured cortical neurons: evidence for caspase-dependent/independent cross-talk.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Apoptosis Regulatory Proteins; Calpain; Caspases; Cells, Cultured; Cerebral Cortex; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neurons; Neurotoxins; Receptor Cross-Talk; Receptors, AMPA; Signal Transduction; Staurosporine | 2007 |
Calbindin-D28K prevents drug-induced dopaminergic neuronal death by inhibiting caspase and calpain activity.
Topics: Animals; Apoptosis; Calbindin 1; Calbindins; Calpain; Caspase Inhibitors; Cell Line; Dopamine; Mice; Neurons; Protein Kinase Inhibitors; S100 Calcium Binding Protein G; Staurosporine | 2008 |
An increase in intracellular Ca2+ is required for the activation of mitochondrial calpain to release AIF during cell death.
Topics: Acrylates; Animals; Apoptosis Inducing Factor; Calcium; Calpain; Cell Death; Cell Line, Tumor; Cytochromes c; Enzyme Activation; Humans; Intracellular Space; Mice; Mitochondria; Models, Biological; Staurosporine | 2008 |
Differential insult-dependent recruitment of the intrinsic mitochondrial pathway during neuronal programmed cell death.
Topics: Animals; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; Calcium; Calpain; Caspase 3; Cells, Cultured; Enzyme Activation; Hydrogen Peroxide; Kainic Acid; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Proteins; Neurons; Staurosporine | 2009 |
Multiple alphaII-spectrin breakdown products distinguish calpain and caspase dominated necrotic and apoptotic cell death pathways.
Topics: Amino Acid Sequence; Animals; Apoptosis; Calpain; Caspases; Cell Death; Edetic Acid; Marine Toxins; Necrosis; Oxocins; PC12 Cells; Rats; Spectrin; Staurosporine | 2009 |
Staurosporine-induced programmed cell death in Blastocystis occurs independently of caspases and cathepsins and is augmented by calpain inhibition.
Topics: Apoptosis; Blastocystis; Calpain; Caspases; Cathepsins; Cysteine Proteases; Cysteine Proteinase Inhibitors; Glycoproteins; Humans; Mitochondria; Staurosporine | 2010 |
Role of cytoskeleton proteins in the morphological changes during apoptotic cell death of cerebellar granule neurons.
Topics: Actins; Animals; Apoptosis; Calpain; Caspase 3; Caspase Inhibitors; Cells, Cultured; Cerebellum; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Ionomycin; Ionophores; Neurons; Potassium; Rats; Rats, Wistar; Staurosporine; Tubulin | 2011 |
Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis.
Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Calcium; Calpain; Caspases; Cell Line; Cell Line, Tumor; Cells, Cultured; Enzyme Inhibitors; Gene Expression; HEK293 Cells; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Neurons; Phosphorylation; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine | 2010 |
The in vitro cleavage of the hAtg proteins by cell death proteases.
Topics: Amino Acid Sequence; Calpain; Caspases; Cell Death; Cytoplasmic Vesicles; Endocytosis; Green Fluorescent Proteins; HeLa Cells; Humans; Microtubule-Associated Proteins; Molecular Sequence Data; Plasmids; Protein Biosynthesis; Recombinant Proteins; Staurosporine; TNF-Related Apoptosis-Inducing Ligand; Transcription, Genetic; Ubiquitin | 2010 |
Hypersensitivity of A8344G MERRF mutated cybrid cells to staurosporine-induced cell death is mediated by calcium-dependent activation of calpains.
Topics: Apoptosis; Bone Neoplasms; Calcium; Calpain; Caspases; Cell Death; Cell Line, Tumor; DNA Mutational Analysis; DNA, Mitochondrial; Humans; Hybrid Cells; MERRF Syndrome; Mutation; Osteosarcoma; Staurosporine | 2012 |
An Involvement of PI3-K/Akt Activation and Inhibition of AIF Translocation in Neuroprotective Effects of Undecylenic Acid (UDA) Against Pro-Apoptotic Factors-Induced Cell Death in Human Neuroblastoma SH-SY5Y Cells.
Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Calpain; Cell Line, Tumor; Chromones; Doxorubicin; Humans; Morpholines; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Staurosporine; Undecylenic Acids | 2015 |
The ATM kinase inhibitor KU-55933 provides neuroprotection against hydrogen peroxide-induced cell damage via a γH2AX/p-p53/caspase-3-independent mechanism: Inhibition of calpain and cathepsin D.
Topics: Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Calpain; Caspase 3; Cathepsin D; Cell Death; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Activation; Histones; Humans; Hydrogen Peroxide; Mice; Morpholines; Neurons; Neuroprotective Agents; Phosphoproteins; Protein Kinase Inhibitors; Pyrones; Rats; Staurosporine; Tumor Suppressor Protein p53 | 2017 |
Novel Peptidomic Approach for Identification of Low and High Molecular Weight Tauopathy Peptides Following Calpain Digestion, and Primary Culture Neurotoxic Challenges.
Topics: Animals; Calcimycin; Calpain; Cells, Cultured; Chromatography, Liquid; Marine Toxins; Mice; Mice, Transgenic; Molecular Weight; N-Methylaspartate; Nanotechnology; Neurons; Oxocins; Peptides; Phosphorylation; Primary Cell Culture; Proteolysis; Rats; Spectrometry, Mass, Electrospray Ionization; Staurosporine; Tandem Mass Spectrometry; tau Proteins | 2019 |
Staurosporine-induced cleavage of apoptosis-inducing factor in human fibrosarcoma cells is independent of matrix metalloproteinase-2.
Topics: Apoptosis; Apoptosis Inducing Factor; Calpain; Cytosol; Fibrosarcoma; Humans; Matrix Metalloproteinase 2; Proteolysis; Staurosporine; Tumor Cells, Cultured | 2022 |