staurosporine has been researched along with bucladesine in 95 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (7.37) | 18.7374 |
| 1990's | 72 (75.79) | 18.2507 |
| 2000's | 16 (16.84) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akkerman, JW; van Willigen, G | 1 |
| Holmes, R; Kelly, E; Perez, HD | 1 |
| Fukuda, M; Maeda, K; Tagami, H; Tomita, Y | 1 |
| Fenton, JW; Garcia, JG; Natarajan, V | 1 |
| Ashcroft, SJ; Goodison, S; Kenna, S | 1 |
| Günther, T; Höllriegl, V; Vormann, J | 1 |
| Kume, S; Ozaki, Y; Yatomi, Y | 1 |
| Koyama, N; Morisaki, N; Saito, Y; Yoshida, S | 1 |
| Beermann, ML; Leli, U; Nixon, RA; Shea, TB | 1 |
| Endo, Y; Furuya, S; Nozawa, S; Oba, M; Suzuki, S | 1 |
| Ishihara, H; Shikita, M; Takeuchi, K; Tsuneoka, K | 1 |
| Okamoto, K; Sakai, Y; Sakuta, H; Sekiguchi, M | 1 |
| Kasuga, M; Konda, Y; Matozaki, T; Matsuda, K; Nagao, M; Nakano, O; Nishisaki, H; Sakamoto, C; Suzuki, T; Wada, K | 1 |
| Tait, JF; Thiagarajan, P | 1 |
| Hibbs, ML; Larson, RS; Springer, TA | 1 |
| Jansen, PL; Ottenhoff, R; Oude Elferink, RP; Roelofsen, H | 1 |
| Chang, CW; Hornsby, PJ; Naseeruddin, SA | 1 |
| Elliott, ME; Goodfriend, TL; Jones, HM; Tomasko, S | 1 |
| Berton, G; Laudanna, C; Miron, S; Rossi, F | 1 |
| Kato, Y; Ogawa, K; Okuda, T; Sawada, H; Tashima, M; Ueda, T; Yumoto, Y | 1 |
| Goodman, HM; Gorin, E; Honeyman, TW; Tai, LR | 1 |
| Dinarello, CA; Morse, C; Zucali, JR | 1 |
| Dustin, ML; Springer, TA | 1 |
| Cabot, MC; Cao, HT; Welsh, CJ; Zhang, ZC | 1 |
| Hagino, A; Hashimoto, S | 2 |
| Biber, J; Murer, H; Quamme, G | 1 |
| Kato, Y; Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H | 1 |
| Fukuzaki, H; Shuntoh, H; Tanaka, C; Taniyama, K | 1 |
| Kachra, Z; Posner, BI; Yang, CR | 1 |
| Bell, LL; Cheung, JY; Lynch, CJ; Miller, BA | 1 |
| McCleskey, EW; Wilding, TJ; Womack, MD | 1 |
| Manzini, S; Palma, C; Urbani, F | 1 |
| Azuma, Y; Ishimura, Y; Kizaki, H; Onishi, Y; Suzuki, K | 1 |
| DiBattista, JA; Iwata, K; Martel-Pelletier, J; Pelletier, JP; Zafarullah, M | 1 |
| Deleu, L; Faisst, S; Kherrouche, Z; Perros, M; Rommelaere, J; Spruyt, N; Vanacker, JM | 1 |
| Jeoung, DI; Sonenberg, M; Tang, B | 1 |
| Alexandre, A; Deana, R; Doni, MG; Francesconi, MA; Padoin, E | 1 |
| Bellido, T; Boland, R; Fernández, LM; Morelli, S | 1 |
| Goodenough, UW | 1 |
| Reyland, ME | 1 |
| Chan, KF; Loh, TT; Lok, CN | 1 |
| Ali, H; DuBose, RA; Haribabu, B; Richardson, RM; Snyderman, R; Tomhave, ED | 1 |
| Björnberg, F; Gullberg, U; Lantz, M; Olsson, I | 1 |
| Collins, CA; Ferro, KL; Lin, SX | 1 |
| Fujimura, S; Kato, N; Miya, T; Sato, K; Tagawa, M; Takahashi, K | 1 |
| Aviram, M; Oiknine, J | 1 |
| Armelin, HA; Armelin, MC; Kimura, E; Sonobe, MH | 1 |
| Calmus, Y; Cherqui, G; Podevin, P; Poupon, R; Robert, A | 1 |
| Snell, WJ; Zhang, Y | 1 |
| Fan, SF; Kao, CY; Wang, S | 1 |
| Boniece, IR; Maiese, K; Skurat, K; Wagner, JA | 1 |
| Izawa, T; Komabayashi, T; Noguchi, M; Suda, K; Tsuboi, M | 1 |
| Gorczynska, E; Handelsman, DJ; Spaliviero, J | 1 |
| Savage, N; Weitzmann, MN | 1 |
| Brenner, HR; Britt, JC; Caroni, P; Rotzler, S | 1 |
| Fadda, GZ; Massry, SG; Smogorzewski, M; Thanakitcharu, P | 1 |
| Koike, Y; Kume, S; Ozaki, Y; Satoh, K; Yatomi, Y | 1 |
| Rossignol, B; Sergheraert, C; Zoukhri, D | 1 |
| Kessels, GC; Krause, KH; Verhoeven, AJ | 1 |
| Aggarwal, S; Coca-Prados, M; Delamere, NA | 1 |
| Miyatake, Y; Nagai, K; Nakagawa, H; Okumura, N | 1 |
| Blum, WF; Ilvesmäki, V; Voutilainen, R | 1 |
| Hengels, KJ; Piontek, M; Porschen, R; Strohmeyer, G | 1 |
| Iwanaga, M; Kohno, M; Sano, M | 1 |
| Cozza, EN; Gomez-Sanchez, CE; Lantos, CP; Pecci, A; Romero, DG | 1 |
| Petersen, MM; Steadman, R; Williams, JD | 1 |
| Bonvoisin, C; Leprince, P; Mazy-Servais, C; Moonen, G; Rogister, B | 1 |
| Müschen, M; Schulz, WA; Sies, H | 1 |
| Cánepa, ET; Varone, CL | 1 |
| Heikkilä, P; Kahri, AI; Liu, J; Voutilainen, R | 3 |
| Hashimoto, Y; Inui, K; Nagai, J; Takano, M; Yano, I | 1 |
| Blanco, G; Mercer, RW | 1 |
| Ito, Y; Kashiwagi, S; Kimura, C; Oike, M | 1 |
| Kamoshima, W; Kitamura, Y; Nomura, Y; Shimohama, S; Taniguchi, T | 1 |
| Barrios de Tomasi, J; González, R; Timossi, CM; Ulloa-Aguirre, A; Zambrano, E | 1 |
| Beil, W; Birkholz, C; Sewing, KF; Wagner, S | 1 |
| Bringmann, A; Reichenbach, A; Schopf, S | 1 |
| Ishida, H; Ishikawa, Y; Skowronski, MT | 1 |
| Campos de Carvalho, AC; Cristancho, JM; Varanda, WA | 1 |
| Chung, HT; Kim, SB; Lee, HS; Pae, HO; Seo, WG; Shin, M | 1 |
| Kits, KS; Lodder, JC; Van Soest, PF | 1 |
| Bönisch, H; Bryan-Lluka, LJ; Paczkowski, FA | 1 |
| Ishikawa, T; Kawai, C; Minatogawa, Y; Sano, M | 1 |
| Hosokawa, M; Ishigamori, H; Kohno, H; Sato, A; Takahashi, K; Tanaka, T | 1 |
| Balaraman, S; Kapoor, P; Madhubala, R; Raj, VS; Saxena, S | 1 |
| Ma, ZJ; Yamaguchi, M | 1 |
| Coleman, R; Elias, E; Milkiewicz, P; Roma, MG | 1 |
| Li, P; Matsunaga, K; Ohizumi, Y; Yamakuni, T | 2 |
| Campos de Carvalho, AC; Cristancho, JM; Fortes, FS; Franci, CR; Goldenberg, RC; Morales, MM; Varanda, WA | 1 |
| Shaikh, SA; Shirsat, NV | 1 |
| Caruso-Neves, C; Einicker-Lamas, M; Masuda, CA; Nascimento, MT; Oliveira, MM | 1 |
95 other study(ies) available for staurosporine and bucladesine
| Article | Year |
|---|---|
Regulation of glycoprotein IIB/IIIA exposure on platelets stimulated with alpha-thrombin.
Topics: Alkaloids; Binding Sites; Blood Platelets; Bucladesine; Epoprostenol; Fibrinogen; Fibronectins; Hirudins; Humans; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Staurosporine; Thrombin | 1992 |
Regulation of formyl peptide receptor expression and its mRNA levels during differentiation of HL-60 cells.
Topics: Alkaloids; Binding Sites; Bucladesine; Cell Differentiation; Chromatography, Liquid; Colforsin; Dexamethasone; Drug Antagonism; Gene Expression Regulation; Humans; Protein Kinase C; Protein Kinases; Receptors, Formyl Peptide; Receptors, Immunologic; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1992 |
Effects of staurosporine, PMA and A23187 on human melanocyte cultures with dibutyryl cyclic AMP.
Topics: Adult; Alkaloids; Bucladesine; Calcimycin; Cells, Cultured; Humans; Male; Melanocytes; Membrane Glycoproteins; Microscopy, Fluorescence; Monophenol Monooxygenase; Oxidoreductases; Protein Kinase C; Proteins; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Thrombin stimulation of human endothelial cell phospholipase D activity. Regulation by phospholipase C, protein kinase C, and cyclic adenosine 3'5'-monophosphate.
Topics: Adenylate Cyclase Toxin; Alkaloids; Bucladesine; Calcimycin; Cell Membrane; Cells, Cultured; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Humans; Ionomycin; Kinetics; Models, Biological; Phorbol Esters; Phospholipase D; Protein Kinase C; Sodium Fluoride; Staurosporine; Thrombin; Type C Phospholipases; Umbilical Veins; Virulence Factors, Bordetella | 1992 |
Control of insulin gene expression by glucose.
Topics: Alkaloids; Blotting, Northern; Bucladesine; Cell Line; Chimera; Chloramphenicol O-Acetyltransferase; Colforsin; Enhancer Elements, Genetic; Gene Expression Regulation; Glucose; Insulin; Islets of Langerhans; Proinsulin; Promoter Regions, Genetic; Protein Kinase C; Protein Kinases; Protein Precursors; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transfection; Verapamil | 1992 |
Isoproterenol-induced Mg2+ uptake in liver.
Topics: Alkaloids; Animals; Bucladesine; Cations, Divalent; Enzyme Activation; In Vitro Techniques; Isoproterenol; Liver; Magnesium; Male; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Synthesis of phosphatidylinositol 3,4-bisphosphate but not phosphatidylinositol 3,4,5-trisphosphate is closely correlated with protein-tyrosine phosphorylation in thrombin-activated human platelets.
Topics: Alkaloids; Blood Platelets; Bucladesine; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Phosphates; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorus Radioisotopes; Phosphorylation; Platelet Activation; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Thrombin; Tyrosine | 1992 |
Regulatory effects of platelet-derived growth factor-AA homodimer on migration of vascular smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Aorta, Thoracic; Biological Factors; Bucladesine; Cell Division; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Fibronectins; Isoquinolines; Kinetics; Macromolecular Substances; Muscle, Smooth, Vascular; Pertussis Toxin; Piperazines; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Wistar; Recombinant Proteins; Second Messenger Systems; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Virulence Factors, Bordetella | 1992 |
Opposing influences of protein kinase activities on neurite outgrowth in human neuroblastoma cells: initiation by kinase A and restriction by kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Bucladesine; Colforsin; Humans; Immunohistochemistry; Isoquinolines; Nervous System Neoplasms; Neurites; Neuroblastoma; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Tumor Cells, Cultured | 1992 |
Effects of modulators of protein kinases and phosphatases on mouse sperm capacitation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bucladesine; Chlortetracycline; Dibutyryl Cyclic GMP; Diglycerides; Ethers, Cyclic; Fluorescence; Genistein; Isoflavones; Isoquinolines; Male; Mice; Okadaic Acid; Peptide Fragments; Phorbol Esters; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Sperm Capacitation; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Barbiturates enhance retinoic acid or 1,25-dihydroxyvitamin D3-induced differentiation of leukemia HL-60 cells.
Topics: Alkaloids; Barbiturates; Bucladesine; Calcitriol; Cell Differentiation; Cell Line; Dactinomycin; Dimethyl Sulfoxide; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; Pentobarbital; Protein Kinase C; Staurosporine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1991 |
Desensitization of endogenous angiotensin II receptors in Xenopus oocytes: a role of protein kinase C.
Topics: Acetylcholine; Alkaloids; Angiotensin II; Animals; Binding Sites; Bucladesine; Dose-Response Relationship, Drug; Electric Conductivity; Hydrolysis; Microbial Collagenase; Oocytes; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Receptors, Angiotensin; Staurosporine; Tetradecanoylphorbol Acetate; Xenopus laevis | 1991 |
Cholecystokinin inhibits phosphatidylcholine synthesis via a Ca(2+)-calmodulin-dependent pathway in isolated rat pancreatic acini. A possible mechanism for diacylglycerol accumulation.
Topics: Alkaloids; Animals; Bombesin; Bucladesine; Calcimycin; Calcium; Calmodulin; Carbachol; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Diglycerides; In Vitro Techniques; Kinetics; Male; Nucleotidyltransferases; Pancreas; Phosphatidylcholines; Protein Kinase C; Rats; Rats, Inbred Strains; Secretin; Sincalide; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tritium | 1991 |
Collagen-induced exposure of anionic phospholipid in platelets and platelet-derived microparticles.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine; Affinity Labels; Alkaloids; Anions; Annexin A5; Binding Sites; Blood Platelets; Bucladesine; Calcimycin; Calcium-Binding Proteins; Colforsin; Collagen; Cyclic GMP; Factor Va; Flow Cytometry; Humans; Nitroprusside; Phospholipids; Platelet Aggregation; Pregnancy Proteins; Signal Transduction; Staurosporine; Theophylline; Thromboplastin | 1991 |
The leukocyte integrin LFA-1 reconstituted by cDNA transfection in a nonhematopoietic cell line is functionally active and not transiently regulated.
Topics: Alkaloids; Animals; Bucladesine; Cell Adhesion Molecules; Cell Line, Transformed; Chlorocebus aethiops; DNA; Epitopes; Fibroblasts; Integrins; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Membrane Proteins; Protein Kinase C; Recombinant Fusion Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1990 |
Hepatocanalicular organic-anion transport is regulated by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Anion Transport Proteins; Anions; Bile Canaliculi; Biological Transport; Bucladesine; Carrier Proteins; Colforsin; Cyclic AMP; Glucagon; Glutathione; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1991 |
The response of 21-hydroxylase messenger ribonucleic acid levels to adenosine 3',5'-monophosphate and 12-O-tetradecanoylphorbol-13-acetate in bovine adrenocortical cells is dependent on culture conditions.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Alkaloids; Animals; Bucladesine; Cattle; Cells, Cultured; Culture Media; Culture Techniques; Cyclic AMP; Enzyme Induction; Kinetics; Male; Orchiectomy; Protein Kinase C; RNA, Messenger; Staurosporine; Steroid 21-Hydroxylase; Tetradecanoylphorbol Acetate | 1991 |
Sphingosine inhibits angiotensin-stimulated aldosterone synthesis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldosterone; Alkaloids; Angiotensin II; Animals; Bucladesine; Cattle; Cells, Cultured; Isoquinolines; Ouabain; Piperazines; Protein Kinase C; Sphingosine; Staurosporine; Zona Glomerulosa | 1991 |
Tumor necrosis factor-alpha/cachectin activates the O2(-)-generating system of human neutrophils independently of the hydrolysis of phosphoinositides and the release of arachidonic acid.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Arachidonic Acids; Bucladesine; Humans; Hydrolysis; In Vitro Techniques; Inositol Phosphates; Isoquinolines; Kinetics; Neutrophils; Pertussis Toxin; Phosphatidic Acids; Phosphatidylinositols; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine; Superoxides; Theophylline; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1990 |
Effect of second-messenger modulators in K-562 cell differentiation: dual action of calcium/phospholipid-dependent protein kinase in the process of differentiation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Northern; Bucladesine; Cell Differentiation; Cell Division; Cell Survival; Cytarabine; Diglycerides; Erythropoiesis; Globins; Hemin; Humans; In Vitro Techniques; Isoquinolines; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Evidence for a role of protein kinase C in the stimulation of lipolysis by growth hormone and isoproterenol.
Topics: Adipose Tissue; Alkaloids; Animals; Bucladesine; Dexamethasone; Drug Synergism; Enzyme Activation; Growth Hormone; Hypophysectomy; Isoproterenol; Lipolysis; Male; Protein Kinase C; Rats; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Theophylline | 1990 |
The role of protein kinase C in interleukin 1 and tumor necrosis factor alpha induction of fibroblasts to produce and release granulocyte-macrophage colony-stimulating activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Alkaloids; Bone Marrow Cells; Bucladesine; Calcium Channel Blockers; Calmodulin; Cell Line; Colforsin; Colony-Forming Units Assay; Colony-Stimulating Factors; Cyclic AMP; Fibroblasts; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Interleukin-1; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Staurosporine; Sulfonamides; Tumor Necrosis Factor-alpha | 1990 |
T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Antigens, Differentiation; Bucladesine; Cell Adhesion; Cell Adhesion Molecules; Colforsin; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; Micelles; Phorbol Esters; Receptors, Antigen, T-Cell; Receptors, Leukocyte-Adhesion; Staurosporine; T-Lymphocytes; Temperature | 1989 |
Evidence for a protein kinase C-directed mechanism in the phorbol diester-induced phospholipase D pathway of diacylglycerol generation from phosphatidylcholine.
Topics: Alkaloids; Animals; Bucladesine; Cell Line; Choline; Colforsin; Diglycerides; Embryo, Mammalian; Fibroblasts; Glycerides; Glycerophospholipids; Hydrolysis; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipases; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Staurosporine-induced neurite outgrowth in PC12h cells.
Topics: Alkaloids; Animals; Axons; Bucladesine; Cell Division; Cell Line; Nerve Growth Factors; Pheochromocytoma; Protein Kinase C; Rats; Staurosporine; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Blockage of nerve growth factor action in PC12h cells by staurosporine, a potent protein kinase inhibitor.
Topics: Adrenal Gland Neoplasms; Alkaloids; Animals; Bucladesine; Cell Line; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Kinetics; Molecular Weight; Neoplasm Proteins; Nerve Growth Factors; Pheochromocytoma; Phosphates; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Rats; Staurosporine; Tumor Cells, Cultured | 1989 |
Sodium-phosphate cotransport in OK cells: inhibition by PTH and "adaptation" to low phosphate.
Topics: Alkaloids; Animals; Bucladesine; Carrier Proteins; Cell Line; Colforsin; Kidney; Kinetics; Parathyroid Hormone; Peptide Fragments; Phosphates; Sodium-Phosphate Cotransporter Proteins; Staurosporine; Symporters; Teriparatide; Tetradecanoylphorbol Acetate | 1989 |
Staurosporine, a novel protein kinase inhibitor, enhances HL-60-cell differentiation induced by various compounds.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Bucladesine; Calcitriol; Cell Differentiation; Dose-Response Relationship, Drug; Drug Synergism; Humans; Isoquinolines; Piperazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1988 |
Inhibition by cyclic AMP of phorbol ester-potentiated norepinephrine release from guinea pig brain cortical synaptosomes.
Topics: Alkaloids; Animals; Bucladesine; Carbazoles; Cerebral Cortex; Colforsin; Cyclic AMP; Enzyme Activation; Female; Guinea Pigs; Indoles; Male; Norepinephrine; Polymyxin B; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Staurosporine; Synaptosomes; Tetradecanoylphorbol Acetate | 1988 |
The augmentation of insulin-like growth factor-I messenger ribonucleic acid in cultured rat hepatocytes: activation of protein kinase-A and -C is necessary, but not sufficient.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Blotting, Northern; Bucladesine; Cattle; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Drug Synergism; Enzyme Activation; Glucagon; Growth Hormone; Insulin-Like Growth Factor I; Isoquinolines; Kinetics; Liver; Male; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Erythropoietin modulation of intracellular calcium: a role for tyrosine phosphorylation.
Topics: Adult; Alkaloids; Analog-Digital Conversion; Biological Transport; Bucladesine; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Erythroid Precursor Cells; Erythropoietin; Genistein; Humans; Image Processing, Computer-Assisted; Indoles; Intercellular Signaling Peptides and Proteins; Intracellular Fluid; Isoflavones; Isoquinolines; Naphthalenes; Peptides; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Pyrroles; Signal Transduction; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Videotape Recording; Wasp Venoms | 1994 |
Fast, local signal transduction between the mu opioid receptor and Ca2+ channels.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Bucladesine; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethers, Cyclic; Ganglia, Spinal; Kinetics; Microcystins; Neurons, Afferent; Okadaic Acid; Patch-Clamp Techniques; Peptides, Cyclic; Pertussis Toxin; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Opioid, mu; Second Messenger Systems; Signal Transduction; Staurosporine; Time Factors; Virulence Factors, Bordetella | 1995 |
Interleukin-6 production by U373 MG, a human astrocytoma cell line: different pathways involved in substance P and lipopolysaccharide activation.
Topics: Alkaloids; Astrocytoma; Bucladesine; Calcimycin; Cholera Toxin; Humans; Indomethacin; Interleukin-6; Lipopolysaccharides; Receptors, Neurokinin-1; Staurosporine; Substance P; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Biphasic effect of staurosporine on thymocyte apoptosis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Apoptosis; Bucladesine; Calcimycin; Carbazoles; Carcinogens; Cells, Cultured; DNA; DNA Damage; Dose-Response Relationship, Drug; Indole Alkaloids; Isoquinolines; Male; Mice; Mice, Inbred BALB C; Piperazines; Protein Kinase Inhibitors; Radiation-Sensitizing Agents; Staurosporine; Tetradecanoylphorbol Acetate; Thymus Gland; Time Factors | 1995 |
Interleukin-1 beta induction of tissue inhibitor of metalloproteinase (TIMP-1) is functionally antagonized by prostaglandin E2 in human synovial fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Northern; Bucladesine; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Glycoproteins; Humans; Immunoenzyme Techniques; Interleukin-1; Isoquinolines; Metalloendopeptidases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Recombinant Proteins; RNA, Messenger; Staurosporine; Synovial Membrane; Tetradecanoylphorbol Acetate; Thionucleotides; Tissue Inhibitor of Metalloproteinases; Up-Regulation | 1995 |
Upstream CREs participate in the basal activity of minute virus of mice promoter P4 and in its stimulation in ras-transformed cells.
Topics: Alkaloids; Animals; Base Sequence; Bucladesine; Cell Line; Cell Line, Transformed; Cell Nucleus; Cyclic AMP-Dependent Protein Kinases; DNA, Viral; Gene Expression Regulation, Viral; Genes, ras; Isoquinolines; Kinetics; Minute Virus of Mice; Molecular Sequence Data; Nucleic Acid Conformation; Plasmids; Promoter Regions, Genetic; Rats; Rats, Inbred F344; Regulatory Sequences, Nucleic Acid; Staurosporine; Sulfonamides; TATA Box; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Viral Nonstructural Proteins | 1995 |
Induction of tumor suppressor p21 protein by kinase inhibitors in MCF-7 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Breast Neoplasms; Bucladesine; Cell Cycle; Cell Division; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Inhibitors; Flow Cytometry; Humans; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; Protein Serine-Threonine Kinases; Staurosporine; Tumor Cells, Cultured | 1995 |
Staurosporine-independent platelet aggregation induced by the calcium ionophore ionomycin is inhibited by prostacyclin and sodium nitroprusside and stimulated by adrenaline.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Bucladesine; Calcium; Cyclic GMP; Epinephrine; Epoprostenol; Humans; Ionomycin; Nitroprusside; Phosphoproteins; Platelet Aggregation; Protein Kinase C; Staurosporine; Yohimbine | 1993 |
Evidence for the participation of protein kinase C and 3',5'-cyclic AMP-dependent protein kinase in the stimulation of muscle cell proliferation by 1,25-dihydroxy-vitamin D3.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Bucladesine; Calcitriol; Calcium; Calcium Channels; Cell Division; Cells, Cultured; Chick Embryo; Colforsin; Diglycerides; DNA; Dose-Response Relationship, Drug; Muscles; Nifedipine; Protein Kinase C; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Tipping of flagellar agglutinins by gametes of Chlamydomonas reinhardtii.
Topics: 1-Methyl-3-isobutylxanthine; Agglutinins; Alkaloids; Animals; Bucladesine; Cadmium; Cell Adhesion; Cell Movement; Chlamydomonas reinhardtii; Colchicine; Diltiazem; Flagella; Germ Cells; Isoquinolines; Lanthanum; Lidocaine; Models, Biological; Plant Proteins; Protozoan Proteins; Reproduction; Staurosporine; Trifluoperazine | 1993 |
Protein kinase C is a tonic negative regulator of steroidogenesis and steroid hydroxylase gene expression in Y1 adrenal cells and functions independently of protein kinase A.
Topics: 3-Hydroxysteroid Dehydrogenases; Adenosine Monophosphate; Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Alkaloids; Animals; Bucladesine; Cholesterol Side-Chain Cleavage Enzyme; Cyclic AMP-Dependent Protein Kinases; Enzyme Induction; Mice; Naphthalenes; Neoplasm Proteins; Polycyclic Compounds; Promoter Regions, Genetic; Protein Kinase C; Recombinant Fusion Proteins; Signal Transduction; Staurosporine; Steroid 11-beta-Hydroxylase; Thionucleotides; Tumor Cells, Cultured | 1993 |
Effects of protein kinase modulators on transferrin receptor expression in human leukaemic HL-60 cells.
Topics: Alkaloids; Bucladesine; Cell Division; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplasm; Enzyme Activation; Gene Expression; Humans; Indoles; Isoquinolines; Leukemia, Promyelocytic, Acute; Maleimides; Protein Kinase C; Protein Kinases; Receptors, Transferrin; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured | 1995 |
Regulation of stably transfected platelet activating factor receptor in RBL-2H3 cells. Role of multiple G proteins and receptor phosphorylation.
Topics: Alkaloids; Amino Acid Sequence; Animals; Bucladesine; Calcium; Cell Line; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Molecular Sequence Data; Pertussis Toxin; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Thionucleotides; Transfection; Virulence Factors, Bordetella | 1994 |
Mechanisms involved in the processing of the p55 and the p75 tumor necrosis factor (TNF) receptors to soluble receptor forms.
Topics: Alkaloids; Ammonium Chloride; Bucladesine; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Endopeptidases; Enzyme-Linked Immunosorbent Assay; HeLa Cells; Humans; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Monensin; Neoplasm Proteins; Protein Kinase C; Protein Processing, Post-Translational; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Solubility; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor Decoy Receptors | 1994 |
Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Alkaloids; Animals; Bucladesine; Calcimycin; Calmodulin; Cell Line; Colforsin; Culture Media; Cytoplasm; Dyneins; Edetic Acid; Ethers, Cyclic; Imidazoles; Kidney; Kinetics; Macromolecular Substances; Okadaic Acid; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate | 1994 |
Prostaglandin E2/parathyroid hormone-induced suppression of alkaline phosphatase activity is mediated by protein kinase C.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Bucladesine; Calcimycin; Cyclic AMP; Cycloheximide; Dinoprostone; Isoquinolines; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Involvement of second messengers in lipopolysaccharide stimulation of low density lipoprotein uptake by macrophages.
Topics: Alkaloids; Animals; Bucladesine; Cells, Cultured; Diglycerides; Enzyme Activation; Humans; Lipopolysaccharides; Lipoproteins, LDL; Macrophages; Mice; Protein Kinase C; Second Messenger Systems; Sphingosine; Staurosporine | 1994 |
Induction of FOS and JUN proteins by adrenocorticotropin and phorbol ester but not by 3',5'-cyclic adenosine monophosphate derivatives.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Alkaloids; Animals; Bucladesine; Colforsin; Cycloheximide; Dactinomycin; Enzyme Induction; Genes, fos; Genes, jun; Kinetics; Mice; Neoplasm Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Inhibition of procoagulant activity of human monocytes by chenodeoxycholic acid: involvement of protein kinase C.
Topics: Alkaloids; Blood Coagulation; Bucladesine; Chenodeoxycholic Acid; Colforsin; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Humans; Monocytes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Flagellar adhesion-dependent regulation of Chlamydomonas adenylyl cyclase in vitro: a possible role for protein kinases in sexual signaling.
Topics: Adenylyl Cyclases; Alkaloids; Animals; Bucladesine; Cell Adhesion; Cell-Free System; Chlamydomonas reinhardtii; Cyclic AMP; Enzyme Activation; Flagella; Gametogenesis; In Vitro Techniques; Protein Kinase Inhibitors; Signal Transduction; Staurosporine | 1994 |
The transduction system in the isoproterenol activation of the Ca(2+)-activated K+ channel in guinea pig taenia coli myocytes.
Topics: Adenylyl Cyclases; Alkaloids; Animals; Bucladesine; Calcium; Calcium Channel Blockers; Cholera Toxin; Colforsin; Colon; Cyclic AMP-Dependent Protein Kinases; Gallic Acid; GTP-Binding Proteins; Guanosine Diphosphate; Guinea Pigs; Isoproterenol; Membrane Potentials; Muscles; Potassium Channels; Protein Kinase C; Signal Transduction; Staurosporine; Thionucleotides | 1993 |
Protein kinases modulate the sensitivity of hippocampal neurons to nitric oxide toxicity and anoxia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bucladesine; Cell Death; Cell Hypoxia; Cells, Cultured; Dibutyryl Cyclic GMP; Hippocampus; Isoquinolines; Nerve Tissue Proteins; Nitric Oxide; Phorbol Esters; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sphingosine; Staurosporine; Sulfonamides | 1993 |
Mechanism of isoprenaline-stimulated diacylglycerol formation in rat parotid acinar cells.
Topics: Alkaloids; Animals; Bucladesine; Cells, Cultured; Colforsin; Diglycerides; In Vitro Techniques; Isoproterenol; Kinetics; Male; Parotid Gland; Phentolamine; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Propranolol; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Staurosporine; Stimulation, Chemical; Vasoactive Intestinal Peptide | 1993 |
The relationship between 3',5'-cyclic adenosine monophosphate and calcium in mediating follicle-stimulating hormone signal transduction in Sertoli cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Alkaloids; Animals; Bucladesine; Calcium; Cyclic AMP; Cytosol; Extracellular Space; Follicle Stimulating Hormone; Male; Pertussis Toxin; Protein Kinase C; Rats; Rats, Wistar; Sertoli Cells; Signal Transduction; Staurosporine; Stereoisomerism; Virulence Factors, Bordetella | 1994 |
Cyclic adenosine 3',5'-monophosphate, a second messenger in interleukin-1 mediated K562 cytostasis.
Topics: Adenylyl Cyclases; Alkaloids; Bucladesine; Cell Division; Colforsin; Cyclic AMP; Humans; Interleukin-1; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Calcium influx and protein phosphorylation mediate the metabolic stabilization of synaptic acetylcholine receptors in muscle.
Topics: Alkaloids; Animals; Bucladesine; Calcium; Calcium Channels; Cyclic AMP; Dibutyryl Cyclic GMP; Dihydropyridines; Electric Stimulation; Ethers, Cyclic; Kinetics; Male; Marine Toxins; Motor Endplate; Muscle Denervation; Muscles; Okadaic Acid; Organ Culture Techniques; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Staurosporine; Synapses; Tetrodotoxin; Time Factors | 1993 |
Parathyroid hormone raises cytosolic calcium in pancreatic islets: study on mechanisms.
Topics: Alkaloids; Animals; Bucladesine; Calcium; Cytosol; GTP-Binding Proteins; In Vitro Techniques; Islets of Langerhans; Male; Parathyroid Hormone; Peptide Fragments; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Teriparatide; Tetradecanoylphorbol Acetate; Verapamil | 1993 |
Wheat germ agglutinin-induced intracellular calcium mobilization in human platelets: suppression by staurosporine and resistance to cyclic AMP inhibition.
Topics: Alkaloids; Alprostadil; Blood Platelets; Bucladesine; Calcium; Cells, Cultured; Cyclic AMP; Enzyme Activation; Humans; In Vitro Techniques; Protein Kinase C; Staurosporine; Thrombin; Type C Phospholipases; Wheat Germ Agglutinins | 1993 |
Phorbol ester-stimulated exocytosis in lacrimal gland: PKC might not be the sole effector.
Topics: Alkaloids; Animals; Benzophenanthridines; Bucladesine; Diglycerides; Exocytosis; In Vitro Techniques; Lacrimal Apparatus; Male; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Trifluoperazine | 1993 |
Protein kinase C activity is not involved in N-formylmethionyl-leucyl-phenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: studies with a staurosporine analogue with improved sel
Topics: Alkaloids; Bucladesine; Enzyme Activation; Humans; In Vitro Techniques; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipase D; Protein Kinase C; Staurosporine; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Studies on regulation of the ascorbic acid transporter in a cell line derived from rabbit non-pigmented ciliary epithelium.
Topics: Alkaloids; Animals; Ascorbic Acid; Biological Transport, Active; Bucladesine; Carrier Proteins; Cell Line; Ciliary Body; Epithelium; Phloretin; Phorbol 12,13-Dibutyrate; Rabbits; Sodium; Staurosporine | 1993 |
The signal transduction pathway for VGF expression due to NGF is different from that due to bFGF in PC12h cell.
Topics: Alkaloids; Animals; Bucladesine; Colforsin; Deoxyadenosines; Fibroblast Growth Factor 2; Heparin; Molecular Weight; Nerve Growth Factors; PC12 Cells; Potassium Chloride; Protein Biosynthesis; Protein Kinase C; Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleosides | 1993 |
Insulin-like growth factor-II in human fetal adrenals: regulation by ACTH, protein kinase C and growth factors.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Alkaloids; Blotting, Northern; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Gene Expression; Gene Expression Regulation; Genes; Growth Substances; Humans; Insulin-Like Growth Factor II; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1993 |
Protein kinase C and adenylate cyclase as targets for growth inhibition of human gastric cancer cells.
Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkaloids; Bucladesine; Cell Division; Colforsin; Enzyme Activation; Humans; Protein Kinase C; Staurosporine; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
The activation and nuclear translocation of extracellular signal-regulated kinases (ERK-1 and -2) appear not to be required for elongation of neurites in PC12D cells.
Topics: Alkaloids; Animals; Biological Transport; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Enzyme Activation; Growth Substances; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurites; PC12 Cells; Protein-Tyrosine Kinases; Rats; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Effects of staurosporine on ACTH-mediated stimulation of aldosterone production.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Bucladesine; Cells, Cultured; Colforsin; Cosyntropin; Dose-Response Relationship, Drug; Male; Peptide Fragments; Protein Kinase C; Rats; Staurosporine; Zona Glomerulosa | 1996 |
Human neutrophil secondary granule exocytosis is independent of protein kinase activation and is modified by calmodulin activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Bucladesine; Calmodulin; Cytoplasmic Granules; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Genistein; Humans; Isoflavones; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vanadates | 1996 |
Protein kinase- and staurosporine-dependent induction of neurite outgrowth and plasminogen activator activity in PC12 cells.
Topics: Animals; Bucladesine; Cell Differentiation; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Nerve Growth Factors; Neurites; PC12 Cells; Plasminogen Activators; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Signal Transduction; Staurosporine; Tissue Plasminogen Activator | 1996 |
Induction of mouse embryonal carcinoma cell differentiation and activation of the retinoic acid receptor beta 2 promoter by 1,25-dihydroxyvitamin D3.
Topics: Animals; Blotting, Northern; Bucladesine; Calcitriol; Carcinoma, Embryonal; Cell Differentiation; Collagen; Cyclic AMP Response Element-Binding Protein; Mice; Promoter Regions, Genetic; Protein Kinase C; Receptors, Retinoic Acid; Staurosporine; Tumor Cells, Cultured | 1996 |
Evidence that protein kinase C is involved in delta-aminolevulinate synthase expression in rat hepatocytes.
Topics: 5-Aminolevulinate Synthetase; Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Diglycerides; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Liver; Male; Naphthalenes; Phenobarbital; Protein Kinase C; Rats; RNA, Messenger; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
Ribonucleic acid expression of the CLA-1 gene, a human homolog to mouse high density lipoprotein receptor SR-BI, in human adrenal tumors and cultured adrenal cells.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Blotting, Northern; Bucladesine; CD36 Antigens; Cells, Cultured; Cushing Syndrome; Gene Expression; Humans; Hyperplasia; Membrane Proteins; Mice; Molecular Sequence Data; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Scavenger Receptors, Class B; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Inhibition of PAH transport by parathyroid hormone in OK cells: involvement of protein kinase C pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Bucladesine; Cell Line; Cell Membrane; Colforsin; Kidney; Kinetics; Mannitol; p-Aminohippuric Acid; Protein Kinase C; Second Messenger Systems; Staurosporine; Teriparatide; Tetradecanoylphorbol Acetate | 1997 |
Regulation of the alpha 2 beta 1 and alpha 3 beta 1 isozymes of the Na,K-ATPase by Ca2+, PKA, and PKC.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Calcium; Cell Line; Cyclic AMP-Dependent Protein Kinases; Macromolecular Substances; Protein Kinase C; Rats; Recombinant Proteins; Sodium-Potassium-Exchanging ATPase; Spodoptera; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Effects of acute glucose overload on histamine H2 receptor-mediated Ca2+ mobilization in bovine cerebral endothelial cells.
Topics: Animals; Bradykinin; Brain; Bucladesine; Calcium; Cattle; Cells, Cultured; Cimetidine; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Glucose; Histamine; Histamine Antagonists; Homeostasis; Microcirculation; Neomycin; Neurotransmitter Agents; Protein Kinase C; Pyrilamine; Ranitidine; Receptors, Histamine H2; Staurosporine | 1998 |
Nitric oxide donor-induced p53-sensitive cell death is enhanced by Bcl-2 reduction in human neuroblastoma cells.
Topics: Animals; bcl-2-Associated X Protein; Bucladesine; Cell Death; Dimerization; DNA Fragmentation; Gene Expression; Genes, p53; Humans; Immunohistochemistry; Mice; Neuroblastoma; Nitric Oxide; Oxidation-Reduction; Penicillamine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; S-Nitroso-N-Acetylpenicillamine; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
A naturally occurring basically charged human follicle-stimulating hormone (FSH) variant inhibits FSH-induced androgen aromatization and tissue-type plasminogen activator enzyme activity in vitro.
Topics: Androgens; Animals; Aromatase; Aromatase Inhibitors; Bucladesine; Cells, Cultured; Cyclic AMP; Electrochemistry; Enzyme Inhibitors; Estrogens; Female; Follicle Stimulating Hormone; Genetic Variation; Granulosa Cells; Humans; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tissue Plasminogen Activator | 1998 |
Helicobacter pylori fatty acid cis 9,10-methyleneoctadecanoic acid increases [Ca2+]i, activates protein kinase C and stimulates acid secretion in parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Calcium Signaling; Carbachol; Diglycerides; Enzyme Activation; Fatty Acids; Gastric Acid; Guinea Pigs; Helicobacter pylori; Histamine; L-Lactate Dehydrogenase; Parietal Cells, Gastric; Phosphatidylserines; Phosphodiesterase Inhibitors; Protein Kinase C; Staurosporine | 1998 |
Protein kinases A and C are opponents in modulating glial Ca2+ -activated K+ channels.
Topics: Animals; Bucladesine; Calcimycin; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Neuroglia; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Calcium-Activated; Protein Kinase C; Rabbits; Retina; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1999 |
pG2 gene expression and its regulation in human adrenocortical and medullary tumors.
Topics: Adenoma; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Medulla; Bucladesine; Cells, Cultured; DNA, Complementary; Gene Expression Regulation; Humans; Pheochromocytoma; RNA, Messenger; Staurosporine; Tumor Cells, Cultured | 1999 |
Enhancement by epinephrine of benzylpenicillin transport in rat small intestine.
Topics: Acetylcholine; Adrenergic Agonists; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Animals; Bucladesine; Cholinergic Agonists; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diet; Enzyme Inhibitors; Epinephrine; Intestine, Small; Isoquinolines; Male; Penicillin G; Penicillins; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Staurosporine | 2000 |
Short term regulation of cell-cell communication in TM3 Leydig cells. A perforated patch study.
Topics: Animals; Bucladesine; Cell Communication; Cell Line; Enzyme Inhibitors; Gap Junctions; Leydig Cells; Male; Mice; Patch-Clamp Techniques; Phorbol Esters; Phosphorylation; Staurosporine | 2000 |
Expression of activin A and its receptors in human pheochromocytomas.
Topics: Activin Receptors; Activins; Adrenal Cortex; Adrenal Cortex Neoplasms; Blotting, Northern; Bucladesine; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Humans; In Situ Hybridization; Inhibins; Pheochromocytoma; Receptors, Growth Factor; RNA, Messenger; Statistics, Nonparametric; Staurosporine; Tumor Cells, Cultured | 2000 |
Protein kinase A or C modulates the apoptosis induced by lectin II isolated from Korean mistletoe, Viscum album var. Coloratum, in the human leukemic HL-60 cells.
Topics: Apoptosis; Bucladesine; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Indoles; Lectins; Mistletoe; Plant Lectins; Plant Preparations; Plant Proteins; Plants, Medicinal; Protein Kinase C; Pyrroles; Ribosome Inactivating Proteins, Type 2; Staurosporine; Tetradecanoylphorbol Acetate; Toxins, Biological | 2000 |
Activation of protein kinase C by oxytocin-related conopressin underlies pacemaker current in Lymnaea central neurons.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Clocks; Bucladesine; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Lymnaea; Neurons; Oxytocin; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Signal Transduction; Staurosporine | 2000 |
Effects of short- and long-term exposure to c-AMP and c-GMP on the noradrenaline transporter.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Bucladesine; Carrier Proteins; Cholera Toxin; Colforsin; COS Cells; Cyclic AMP; Cyclic GMP; Humans; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; PC12 Cells; Rats; RNA, Messenger; Staurosporine; Symporters; Time Factors; Tumor Cells, Cultured | 2001 |
Peroxisomes exist in growth cones and move anterogradely and retrogradely in neurites of PC12D cells.
Topics: Amino Acid Motifs; Animals; Bucladesine; Colforsin; Green Fluorescent Proteins; Growth Cones; Kinetics; Luminescent Proteins; Models, Neurological; Movement; Neurites; PC12 Cells; Peroxisomes; Rats; Recombinant Fusion Proteins; Staurosporine | 2001 |
Synergistic effects of highly unsaturated fatty acid-containing phosphatidyl-ethanolamine on differentiation of human leukemia HL-60 cells by dibutyryl cyclic adenosine monophosphate.
Topics: Animals; Bucladesine; Cell Differentiation; Cell Division; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fatty Acids, Unsaturated; HL-60 Cells; Humans; Isoquinolines; Male; Nitroblue Tetrazolium; Phosphatidylethanolamines; Phospholipids; Salmon; Signal Transduction; Staurosporine; Testis; Time Factors | 2001 |
Effect of Leishmania donovani lipophosphoglycan on ornithine decarboxylase activity in macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Bacterial Agents; Bucladesine; Calcimycin; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glycosphingolipids; Leishmania donovani; Leishmaniasis, Visceral; Lipopolysaccharides; Macrophages; Mice; Okadaic Acid; Ornithine Decarboxylase; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Inhibitory effect of menaquinone-7 (vitamin K2) on osteoclast-like cell formation and osteoclastic bone resorption in rat bone tissues in vitro.
Topics: Animals; Bone and Bones; Bone Marrow Cells; Bone Resorption; Bucladesine; Calcitonin; Calcium; Carcinogens; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Hemostatics; Male; Osteoclasts; Oxytocics; Peptide Fragments; Rats; Rats, Wistar; Staurosporine; Teriparatide; Tetradecanoylphorbol Acetate; Vitamin K 2 | 2001 |
Hepatoprotection with tauroursodeoxycholate and beta muricholate against taurolithocholate induced cholestasis: involvement of signal transduction pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Bucladesine; Calcium; Carbazoles; Chelating Agents; Cholagogues and Choleretics; Cholestasis; Cholic Acids; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Indoles; Liver; Male; Protein Kinase C; Pyrroles; Rats; Signal Transduction; Staurosporine; Taurochenodeoxycholic Acid; Taurolithocholic Acid | 2002 |
Picrosides I and II, selective enhancers of the mitogen-activated protein kinase-dependent signaling pathway in the action of neuritogenic substances on PC12D cells.
Topics: Animals; Blotting, Western; Bucladesine; Cinnamates; Enzyme Inhibitors; Fibroblast Growth Factor 2; Glucosides; Indoles; Iridoid Glucosides; Maleimides; Mitogen-Activated Protein Kinases; Neurites; PC12 Cells; Phosphorylation; Rats; Signal Transduction; Staurosporine; Stimulation, Chemical | 2002 |
Modulation of gap junction mediated intercellular communication in TM3 Leydig cells.
Topics: Animals; Biological Transport; Bucladesine; Cell Adhesion; Cell Line; Cell Membrane; Coloring Agents; Connexin 43; Enzyme Inhibitors; Fluorescent Antibody Technique; Gap Junctions; Glyceraldehyde-3-Phosphate Dehydrogenases; Isoquinolines; Leydig Cells; Luteinizing Hormone; Male; Mice; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Testosterone; Tetradecanoylphorbol Acetate; Time Factors | 2003 |
Overexpression of the immediate early gene fra-1 inhibits proliferation, induces apoptosis, and reduces tumourigenicity of c6 glioma cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Apoptosis; Astrocytoma; Brain Neoplasms; Bucladesine; Cell Differentiation; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Clone Cells; Enzyme Inhibitors; Feedback, Physiological; Gene Expression Regulation, Neoplastic; Glioma; Proto-Oncogene Proteins c-fos; Rats; Staurosporine; Transcription Factor AP-1 | 2003 |
Nardosinone, the first enhancer of neurite outgrowth-promoting activity of staurosporine and dibutyryl cyclic AMP in PC12D cells.
Topics: Animals; Bucladesine; Cell Differentiation; Central Nervous System; Dose-Response Relationship, Drug; Drug Synergism; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavonoids; MAP Kinase Signaling System; Neurites; PC12 Cells; Phosphorylation; Polycyclic Sesquiterpenes; Rats; Sesquiterpenes; Staurosporine | 2003 |
Trypanosoma cruzi epimastigotes: regulation of myo-inositol transport by effectors of protein kinases A and C.
Topics: Animals; Biological Transport; Bucladesine; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Inositol; Kinetics; Phosphorylation; Protein Kinase C; Pyrroles; Signal Transduction; Sphingosine; Staurosporine; Trypanosoma cruzi | 2007 |