staurosporine has been researched along with bryostatin 1 in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (77.78) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gschwendt, M; Kittstein, W; Lindner, D; Marks, F | 1 |
| Deli, E; Kiss, Z | 1 |
| Bradshaw, TD; Gescher, A; Pettit, GR | 1 |
| Adler, WH; Boto, WM; Brown, L; Chrest, J | 1 |
| Armstrong, DK; Davidson, NE; Ito, T; May, WS; Qatsha, KA; Tyler, PG | 1 |
| Gschwendt, M; Kielbassa, K; Marks, F; Müller, HJ; Zang, R | 1 |
| DeLeo, VA; Illarda, I; Matsui, MS; Wang, N | 1 |
| Akerman, K; Heikkilä, J; Jalava, A | 1 |
| Campbell, XZ; Neet, KE | 1 |
| Bartimole, TM; Dent, P; Freemerman, AJ; Grant, S; Jarvis, WD; Kramer, LB; Krystal, G; Vrana, JA; Wang, S | 1 |
| Crowther, D; Haran, MS; Jayson, G; McGown, AT; Pettit, GR; Ward, TH | 1 |
| Byrd, JC; Grever, MR; Rai, KR; Sausville, EA | 1 |
| Ekinci, FJ; Shea, TB | 1 |
| Grant, S; Jarvis, WD | 1 |
| Kaye, SB; Swannie, HC | 1 |
| Lange, Y; Steck, TL; Ye, J | 1 |
| da Rocha, AB; Mans, DR; Regner, A; Schwartsmann, G | 1 |
| Grant, S; Wang, S; Wang, Z | 1 |
4 review(s) available for staurosporine and bryostatin 1
| Article | Year |
|---|---|
Old and new therapies in chronic lymphocytic leukemia: now is the time for a reassessment of therapeutic goals.
Topics: Alkaloids; Antineoplastic Agents, Alkylating; Bryostatins; Flavonoids; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Piperidines; Staurosporine; Topoisomerase I Inhibitors | 1998 |
Protein kinase C targeting in antineoplastic treatment strategies.
Topics: Animals; Antineoplastic Agents; Bryostatins; Cell Survival; Cytoprotection; Enzyme Inhibitors; Humans; Lactones; Macrolides; Mitogen-Activated Protein Kinase Kinases; Naphthalenes; Protein Kinase C; Sphingosine; Staurosporine | 1999 |
Protein kinase C inhibitors.
Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Bryostatins; Clinical Trials as Topic; Drug Resistance, Multiple; Enzyme Activation; Enzyme Inhibitors; Humans; Lactones; Macrolides; Molecular Structure; Oligodeoxyribonucleotides, Antisense; Protein Kinase C; Research Design; Staurosporine; Thionucleotides; Tumor Cells, Cultured | 2002 |
Targeting protein kinase C: new therapeutic opportunities against high-grade malignant gliomas?
Topics: Adolescent; Adult; Antineoplastic Agents; Apoptosis; Bryostatins; Cell Division; Child; Child, Preschool; Enzyme Activation; Enzyme Inhibitors; Glioma; Humans; Infant; Lactones; Macrolides; Mutation; Naphthalenes; Neoplasm Invasiveness; Neoplasm Proteins; Phenotype; Protein Kinase C; Sphingosine; Staurosporine | 2002 |
14 other study(ies) available for staurosporine and bryostatin 1
| Article | Year |
|---|---|
Differential inhibition by staurosporine of phorbol ester, bryostatin and okadaic acid effects on mouse skin.
Topics: Alkaloids; Animals; Bryostatins; Cyclosporine; Edema; Ethers, Cyclic; Female; Lactones; Macrolides; Mice; Okadaic Acid; Protein Kinase C; Skin; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Regulation of phospholipase D by sphingosine involves both protein kinase C-dependent and -independent mechanisms in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Alkaloids; Animals; Bryostatins; Down-Regulation; Drug Interactions; Ethers, Cyclic; Hydrolysis; Lactones; Macrolides; Mice; Okadaic Acid; Phosphatidylethanolamines; Phospholipase D; Phospholipids; Platelet-Derived Growth Factor; Protein Kinase C; Sphingomyelin Phosphodiesterase; Sphingosine; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1992 |
Modulation by staurosporine of phorbol-ester-induced effects on growth and protein kinase C localization in A549 human lung-carcinoma cells.
Topics: Alkaloids; Bryostatins; Cell Division; DNA; Down-Regulation; Enzyme Activation; Humans; Lactones; Lung Neoplasms; Macrolides; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Distinct modulatory effects of bryostatin 1 and staurosporine on the biosynthesis and expression of the HIV receptor protein (CD4) by T cells.
Topics: Adjuvants, Immunologic; Alkaloids; Bryostatins; CD4 Antigens; Gene Expression Regulation; Glycosylation; Humans; In Vitro Techniques; Interleukin-2; Lactones; Macrolides; Protein Kinase C; Receptors, HIV; Staurosporine; T-Lymphocytes | 1991 |
Interleukin-3 and bryostatin-1 mediate hyperphosphorylation of BCL2 alpha in association with suppression of apoptosis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Bryostatins; Cells, Cultured; Cloning, Molecular; Erythropoietin; Hematopoietic Stem Cells; Interleukin-3; Isoquinolines; Lactones; Macrolides; Mice; Mitogens; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Piperazines; Precipitin Tests; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Staurosporine | 1994 |
Partial purification of a type eta protein kinase C from murine brain: separation from other protein kinase C isoenzymes and characterization.
Topics: Alkaloids; Amino Acid Sequence; Animals; Baculoviridae; Brain; Bryostatins; Cell Line; Chromatography; Cytosol; Enzyme Activation; Gene Transfer Techniques; Immunosorbent Techniques; Isoenzymes; Lactones; Macrolides; Mice; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Recombinant Proteins; Spodoptera; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Protein kinase C agonist and antagonist effects in normal human epidermal keratinocytes.
Topics: Alkaloids; Amino Acid Sequence; Bryostatins; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Enzyme Activation; Enzyme Induction; Epidermal Cells; Etretinate; Humans; Keratinocytes; Lactones; Macrolides; Molecular Sequence Data; Protein Kinase C; Protein Synthesis Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Protein kinase inhibitor, staurosporine, induces a mature neuronal phenotype in SH-SY5Y human neuroblastoma cells through an alpha-, beta-, and zeta-protein kinase C-independent pathway.
Topics: Alkaloids; Bryostatins; Cell Differentiation; Cellular Senescence; Gene Expression; Genes, fos; Humans; Lactones; Macrolides; Neuroblastoma; Neurons; Phenotype; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Mas; Staurosporine; Subcellular Fractions; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Hierarchical analysis of the nerve growth factor-dependent and nerve growth factor-independent differentiation signaling pathways in PC12 cells with protein kinase inhibitors.
Topics: Alkaloids; Animals; Bryostatins; Carbazoles; Cell Differentiation; Enzyme Inhibitors; Fibroblast Growth Factor 2; Indole Alkaloids; Lactones; Macrolides; Models, Biological; Neoplasm Proteins; Nerve Growth Factors; Nerve Tissue Proteins; Neurites; Neurons; PC12 Cells; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins p21(ras); Rats; Signal Transduction; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Thioguanine | 1995 |
Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2.
Topics: Alkaloids; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Western; Bryostatins; Cytarabine; DNA, Neoplasm; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Endopeptidases; Enzyme Inhibitors; HL-60 Cells; Humans; Lactones; Macrolides; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Staurosporine | 1997 |
Bryostatin 1-tamoxifen combinations show synergistic effects on the inhibition of growth of P388 cells in vitro.
Topics: Animals; Bryostatins; Cell Division; Drug Synergism; Enzyme Activation; Growth Inhibitors; Lactones; Leukemia P388; Macrolides; Mice; Protein Kinase C; Staurosporine; Tamoxifen; Tetradecanoylphorbol Acetate | 1998 |
Selective activation by bryostatin-1 demonstrates unique roles for PKC epsilon in neurite extension and tau phosphorylation.
Topics: Bryostatins; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Lactones; Macrolides; Neurites; Neurons; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Staurosporine; tau Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Effect of protein kinase C on endoplasmic reticulum cholesterol.
Topics: Acetophenones; Benzopyrans; Bryostatins; Calcium; Cell Membrane; Cells, Cultured; Cholesterol; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Enzyme Inhibitors; Fibroblasts; Humans; Lactones; Macrolides; Mitogens; Naphthalenes; Protein Isoforms; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 2002 |
Bryostatin 1 and UCN-01 potentiate 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human myeloid leukemia cells through disparate mechanisms.
Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bryostatins; Carrier Proteins; Caspases; Cytarabine; Cytochrome c Group; Drug Synergism; Enzyme Activation; Gene Deletion; HL-60 Cells; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Lactones; Leukemia, Myeloid; Macrolides; Maleimides; Mitochondrial Proteins; Mutation; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Receptors, Tumor Necrosis Factor; Staurosporine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; U937 Cells | 2003 |