staurosporine has been researched along with bi 2536 in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Giranda, VL; Johnson, EF; Luo, Y; Stewart, KD; Woods, KW | 1 |
| Ciceri, P; Davis, MI; Herrgard, S; Hocker, M; Hunt, JP; Pallares, G; Treiber, DK; Wodicka, LM; Zarrinkar, PP | 1 |
| Cao, D; Chen, YL; Damaneh, MS; Hu, J; Li, Y; Meng, T; Miao, Z; Shen, J; Song, S; Wang, X; Wang, Y; Xiong, B; Xu, L | 1 |
| Cheng, K; Li, S; Liao, C; Luo, J; Tu, Z; Xiao, X; Xie, Z; Yang, Y; Zhan, MM; Zhang, XX | 1 |
| Cao, D; Chen, L; Chen, Y; Damaneh, MS; Hu, J; Li, J; Li, Y; Miao, Z; Shen, J; Song, S; Wang, X; Wang, Y; Xiong, B; Xu, L | 1 |
| Cao, P; Han, J; Liao, C; Lv, X; Peng, R; Tu, Z; Xie, Z; Yang, X; Zhan, MM; Zheng, S | 1 |
| Dong, H; Guo, X; Han, B; Hong, X; Jiang, W; Liu, K; Lu, S; Qiu, F; Qiu, X; Qu, L; Shi, T; Tian, L; Wu, Z; Yao, K; Zhao, J; Zhao, W; Zhong, L; Zhong, M; Zhou, B | 1 |
7 other study(ies) available for staurosporine and bi 2536
| Article | Year |
|---|---|
Pharmacological and functional comparison of the polo-like kinase family: insight into inhibitor and substrate specificity.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Androstadienes; Binding Sites; Cell Cycle Proteins; Humans; Models, Molecular; Molecular Sequence Data; Peptide Library; Polo-Like Kinase 1; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Substrate Specificity; Wortmannin | 2007 |
Comprehensive analysis of kinase inhibitor selectivity.
Topics: Catalysis; Drug Design; Enzyme Stability; High-Throughput Screening Assays; Humans; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Proteomics; Signal Transduction; Substrate Specificity | 2011 |
Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor.
Topics: Animals; Antineoplastic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Nuclear Proteins; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Quinoxalines; Structure-Activity Relationship; Transcription Factors; Xenograft Model Antitumor Assays | 2017 |
Design, synthesis, and biological evaluation of novel highly selective polo-like kinase 2 inhibitors based on the tetrahydropteridin chemical scaffold.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pteridines; Structure-Activity Relationship | 2018 |
Structure-based optimization of a series of selective BET inhibitors containing aniline or indoline groups.
Topics: Aniline Compounds; B7-H1 Antigen; Cell Cycle Proteins; Dose-Response Relationship, Drug; Humans; Indoles; Molecular Structure; Nuclear Proteins; Proto-Oncogene Proteins c-myc; Structure-Activity Relationship; Transcription Factors | 2018 |
Structure-based design and SAR development of novel selective polo-like kinase 1 inhibitors having the tetrahydropteridin scaffold.
Topics: Antineoplastic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Structure-Activity Relationship | 2019 |
PLK1/NF-κB feedforward circuit antagonizes the mono-ADP-ribosyltransferase activity of PARP10 and facilitates HCC progression.
Topics: Animals; Antineoplastic Agents; Carcinogenesis; Carcinoma, Hepatocellular; Cell Cycle Proteins; Disease Progression; Feedback, Physiological; Female; HEK293 Cells; Hepatectomy; Humans; Kaplan-Meier Estimate; Liver; Liver Neoplasms; Male; Mice; Middle Aged; Mutagenesis, Site-Directed; Neoplasm Staging; Nitriles; Phosphorylation; Polo-Like Kinase 1; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Signal Transduction; Staurosporine; Sulfones; Transcription Factor RelA; Xenograft Model Antitumor Assays | 2020 |