Page last updated: 2024-08-23

staurosporine and aspartic acid

staurosporine has been researched along with aspartic acid in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (33.33)18.2507
2000's12 (57.14)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adu, J; Burgoyne, RD; Cambray-Deakin, MA1
Bussolati, O; Franchi-Gazzola, R; Gazzola, GC; Visigalli, R1
Lundy, DF; McBean, GJ1
Gilbertsen, RB; McGinnis, K; Nadimpalli, R; Posmantur, R; Wang, KK1
Crosson, CE; Ganel, R1
Gnegy, ME; McGinnis, KM; Wang, KK; Whitton, MM1
Gnegy, ME; McGinnis, KM; Mukerjee, N; Park, YH; Wang, KK1
Keogh, SA; Martin, SJ; Slee, EA1
Byun, Y; Chang, R; Chen, F; Cryns, VL; Green, KJ; Trivedi, M1
Evan, GI; Kruidering, M; Schouten, T; Vreugdenhil, E1
Collins, M; Graves, LM; Haystead, TA; Huang, M; Kozlowski, P; Wang, Y1
Kayama, T; Kitanaka, C; Kokubu, A; Kuchino, Y; Sakurada, K; Sunayama, J; Tomiyama, A1
Koh, YH; Tanzi, RE; Tesco, G1
Exton, JH; Hu, T1
Arber, DA; Berubé, C; Chen, CC; Cohen, PS; Coutré, SE; Durocher, JA; Galli, SJ; George, TI; Gilliland, DG; Gotlib, J; Growney, JD; Heinrich, MC; Kajiguchi, T; Lichy, JH; Lilleberg, SL; Neckers, L; Ruan, J; Wang, Y; Williams, C1
Armstrong, EJ; Hemendinger, RA; Mougeot, JL; Persinski, R; Rosenfeld, J; Todd, J; Volvovitz, F1
Ahn, SK; Bae, S; Cha, HJ; Jin, YW; Jung, JH; Kim, CS; Lee, J; Lee, SJ; Park, IC; Seo, SK; Sohn, I; Woo, SH; Yang, KH; Yoo, H; Yu, EO1
Cardinale, S; Carvalho, A; Earnshaw, WC; Gassmann, R; Gudmundsdottir, E; Lai, F; Morrison, CG; Ogawa, H; Ribeiro, S; Ruchaud, S; Xu, Z; Yuan, X; Yue, Z1
Furuchi, T; Homma, H; Katane, M; Sekine, M; Suzuki, T1
Du, ZX; Gao, YY; Liu, BQ; Meng, X; Niu, XF; Wang, HQ; Zhang, HY1
Ingham, RJ; Lee, JK; Maser, BE; Pearson, JD1

Other Studies

21 other study(ies) available for staurosporine and aspartic acid

ArticleYear
Neuritogenesis in cerebellar granule cells in vitro: a role for protein kinase C.
    Brain research. Developmental brain research, 1990, Apr-01, Volume: 53, Issue:1

    Topics: Alkaloids; Animals; Aspartic Acid; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebellum; Dendrites; Enzyme Inhibitors; N-Methylaspartate; Protein Kinase C; Rats; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate

1990
The regulation of sodium-dependent transport of anionic amino acids in cultured human fibroblasts.
    FEBS letters, 1994, Sep-26, Volume: 352, Issue:2

    Topics: Adolescent; Alkaloids; Arginine; Aspartic Acid; Becaplermin; Biological Transport; Bradykinin; Cells, Cultured; Down-Regulation; Enzyme Activation; Fibroblasts; Humans; Male; Membrane Potentials; Phorbol 12,13-Dibutyrate; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogene Proteins c-sis; Skin; Sodium; Staurosporine

1994
Inhibition of the high-affinity uptake of D-[3H]aspartate in rate by L-alpha-aminoadipate and arachidonic acid.
    Journal of the neurological sciences, 1996, Volume: 139 Suppl

    Topics: 2-Aminoadipic Acid; Animals; Arachidonic Acid; Aspartic Acid; Biological Transport; Brain; Brain Chemistry; Carcinogens; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamate-Cysteine Ligase; Glutamic Acid; Organ Culture Techniques; Phorbol Esters; Rats; Staurosporine; Tritium

1996
Characterization of CPP32-like protease activity following apoptotic challenge in SH-SY5Y neuroblastoma cells.
    Journal of neurochemistry, 1997, Volume: 68, Issue:6

    Topics: Antibody Specificity; Apoptosis; Aspartic Acid; Caspase 1; Caspase 3; Caspases; Coumarins; Cysteine Endopeptidases; DNA; Enzyme Inhibitors; Enzyme Precursors; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; Hydrolysis; Neuroblastoma; Neurons; Oligopeptides; Poly(ADP-ribose) Polymerases; Protease Inhibitors; Staurosporine; Tumor Cells, Cultured

1997
Modulation of human glutamate transporter activity by phorbol ester.
    Journal of neurochemistry, 1998, Volume: 70, Issue:3

    Topics: Amino Acid Transport System X-AG; Anti-Bacterial Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Carcinogens; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamates; Glutamic Acid; Humans; Kainic Acid; Kinetics; Phorbol Esters; Protein Kinase C; Retinoblastoma; Staurosporine; Tumor Cells, Cultured

1998
Calcium/calmodulin-dependent protein kinase IV is cleaved by caspase-3 and calpain in SH-SY5Y human neuroblastoma cells undergoing apoptosis.
    The Journal of biological chemistry, 1998, Aug-07, Volume: 273, Issue:32

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Aspartic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Calpain; Caspase 3; Caspases; Chlorobenzoates; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Mice; Neuroblastoma; Peptide Fragments; Recombinant Proteins; Staurosporine; Thapsigargin; Tumor Cells, Cultured

1998
Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates.
    Biochemical and biophysical research communications, 1999, Sep-16, Volume: 263, Issue:1

    Topics: Acetylcysteine; Aspartic Acid; Calpain; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Precursors; Humans; Marine Toxins; Oxocins; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Staurosporine; Substrate Specificity

1999
Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release.
    Cell death and differentiation, 2000, Volume: 7, Issue:6

    Topics: Animals; Apoptosis; Aspartic Acid; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspase 3; Caspases; Catalysis; Cell-Free System; Cycloheximide; Cytochrome c Group; Enzyme Inhibitors; Etoposide; Humans; Jurkat Cells; Mice; Mitochondria, Liver; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Tumor Cells, Cultured; Ultraviolet Rays

2000
Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis.
    Cell death and differentiation, 2001, Volume: 8, Issue:5

    Topics: Apoptosis; Aspartic Acid; Carrier Proteins; Caspase 3; Caspase 6; Caspase 7; Caspase Inhibitors; Caspases; Cell Line; Cloning, Molecular; Cycloheximide; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Intermediate Filaments; Microfilament Proteins; Mutation; Protein Processing, Post-Translational; Staurosporine; Transfection; Tumor Necrosis Factor-alpha; Vimentin

2001
Caspase-mediated cleavage of the Ca2+/calmodulin-dependent protein kinase-like kinase facilitates neuronal apoptosis.
    The Journal of biological chemistry, 2001, Oct-19, Volume: 276, Issue:42

    Topics: Animals; Apoptosis; Asparagine; Aspartic Acid; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Line; Cells, Cultured; Culture Media, Serum-Free; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Immunohistochemistry; Neurons; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Rabbits; Reticulocytes; Reverse Transcriptase Polymerase Chain Reaction; Staurosporine; Subcellular Fractions; Tumor Cells, Cultured

2001
Caspase-dependent cleavage of carbamoyl phosphate synthetase II during apoptosis.
    Molecular pharmacology, 2002, Volume: 61, Issue:3

    Topics: Animals; Apoptosis; Aspartic Acid; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Caspase 3; Caspases; Cell Line; Drug Resistance; Enzyme Inhibitors; Humans; Interleukin-3; Mice; Peptide Hydrolases; Phosphonoacetic Acid; Protein Structure, Tertiary; Staurosporine; Tumor Cells, Cultured; Uridine Triphosphate

2002
A cellular mechanism that reversibly inactivates pancaspase inhibitor zAsp-CH(2)-DCB: a potential pitfall causing discrepancy between in vitro and in vivo caspase assays.
    Biochemical and biophysical research communications, 2002, Mar-08, Volume: 291, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Aspartic Acid; Caspase Inhibitors; Caspases; Cytoplasm; Dose-Response Relationship, Drug; Enzyme Precursors; HeLa Cells; Humans; Kinetics; Neuroblastoma; Poly(ADP-ribose) Polymerases; Protease Inhibitors; Research Design; Staurosporine; Tumor Cells, Cultured

2002
Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP).
    The Journal of biological chemistry, 2003, Nov-14, Volume: 278, Issue:46

    Topics: Amyloid beta-Peptides; Animals; Apoptosis; Aspartic Acid; Binding Sites; Blotting, Western; Caspase 3; Caspases; CHO Cells; Cricetinae; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Etoposide; In Situ Nick-End Labeling; Mutagenesis, Site-Directed; Nucleic Acid Synthesis Inhibitors; Protein Binding; Protein Structure, Tertiary; Staurosporine; Time Factors; Transfection

2003
1-Butanol interferes with phospholipase D1 and protein kinase Calpha association and inhibits phospholipase D1 basal activity.
    Biochemical and biophysical research communications, 2005, Feb-25, Volume: 327, Issue:4

    Topics: 1-Butanol; Amino Acid Substitution; Animals; Aspartic Acid; Chlorocebus aethiops; COS Cells; Enzyme Inhibitors; Mutagenesis, Site-Directed; Phospholipase D; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Rats; Staurosporine; Time Factors

2005
Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation.
    Blood, 2005, Oct-15, Volume: 106, Issue:8

    Topics: Aspartic Acid; Cell Proliferation; Cells, Cultured; Female; Humans; Immunophenotyping; Leukemia, Mast-Cell; Middle Aged; Mutation; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Staurosporine

2005
Huperzine A provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death.
    Neurotoxicity research, 2008, Volume: 13, Issue:1

    Topics: Alkaloids; Animals; Apoptosis; Aspartic Acid; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Drug Interactions; Enzyme Inhibitors; Hydrogen Peroxide; Ionophores; Motor Neurons; Neuroprotective Agents; Organ Culture Techniques; Oxidants; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Spinal Cord; Staurosporine; Thapsigargin

2008
Specific proteolysis of the A-kinase-anchoring protein 149 at the Asp582 residue by caspases during apoptosis.
    Oncology reports, 2008, Volume: 19, Issue:6

    Topics: A Kinase Anchor Proteins; Apoptosis; Aspartic Acid; Caspases; fas Receptor; HeLa Cells; Humans; Jurkat Cells; Mutation; Staurosporine

2008
Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line.
    The Journal of cell biology, 2008, Oct-20, Volume: 183, Issue:2

    Topics: Amino Acid Motifs; Animals; Aspartic Acid; Aurora Kinases; Cell Death; Cell Line; Cell Separation; Cell Survival; Centromere; Chickens; Cyclin-Dependent Kinases; Cytokinesis; Etoposide; Microtubule-Associated Proteins; Mitochondrial Proteins; Mitosis; Mutation; Phenotype; Phosphorylation; Phosphothreonine; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Spindle Apparatus; Staurosporine; Temperature; Vertebrates

2008
Apoptotic inducers activate the release of D-aspartate through a hypotonic stimulus-triggered mechanism in PC12 cells.
    Archives of biochemistry and biophysics, 2009, Oct-15, Volume: 490, Issue:2

    Topics: Animals; Apoptosis; Aspartic Acid; Calcimycin; Hydrogen Peroxide; Hypotonic Solutions; Ion Channels; Ionophores; Nitrobenzoates; PC12 Cells; Rats; Sphingosine; Staurosporine; Stereoisomerism; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Uric Acid

2009
Characterization of BAG3 cleavage during apoptosis of pancreatic cancer cells.
    Journal of cellular physiology, 2010, Volume: 224, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptosis Regulatory Proteins; Aspartic Acid; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Etoposide; Humans; Leupeptins; Mutation; Pancreatic Neoplasms; Peptide Fragments; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Proteins; Staurosporine; Time Factors; Transfection; Tumor Necrosis Factor-alpha; Ultraviolet Rays

2010
Cleavage of the JunB transcription factor by caspases generates a carboxyl-terminal fragment that inhibits activator protein-1 transcriptional activity.
    The Journal of biological chemistry, 2013, Jul-26, Volume: 288, Issue:30

    Topics: Amino Acid Sequence; Anaplastic Lymphoma Kinase; Animals; Antigens, Bacterial; Apoptosis; Apoptosis Regulatory Proteins; Aspartic Acid; Bacterial Toxins; Binding Sites; Blotting, Western; Caspases; Cell Line; Cell Line, Tumor; Humans; Lymphoma, Large-Cell, Anaplastic; Macrophages; Mice; Molecular Sequence Data; Mutation; Peptide Fragments; Protein Binding; Receptor Protein-Tyrosine Kinases; Sequence Homology, Amino Acid; Staurosporine; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic

2013