Compounds > staurosporine
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staurosporine and apigenin

staurosporine has been researched along with apigenin in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Chang, CJ; Geahlen, RL1
Habtemariam, S1
Bain, J; Battistutta, R; de Moliner, E; Elliott, M; Fabbro, D; Furet, P; Meggio, F; Pagano, MA; Pinna, LA; Ruzzene, M; Sarno, S; Schoepfer, J; Zanotti, G1
Bhattacharjee, AK; Geyer, JA; Kathcart, AK; Li, Z; Mott, BT; Nichols, DA; Prigge, ST; Waters, NC; Woodard, CL1
Bullock, AN; Debreczeni, JE; Fedorov, OY; Knapp, S; Marsden, BD; Nelson, A1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Fujita-Yamaguchi, Y; Kathuria, S1
D'Agostino, PM; Gulder, TAM; Mojicevic, M; Nikodinovic-Runic, J; Pavic, A; Senthamaraikannan, R; Vasiljevic, B; Vojnovic, S1

Reviews

1 review(s) available for staurosporine and apigenin

ArticleYear
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
    Journal of natural products, 1992, Volume: 55, Issue:11

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases

1992

Other Studies

7 other study(ies) available for staurosporine and apigenin

ArticleYear
Flavonoids as inhibitors or enhancers of the cytotoxicity of tumor necrosis factor-alpha in L-929 tumor cells.
    Journal of natural products, 1997, Volume: 60, Issue:8

    Topics: Animals; Apoptosis; Drug Synergism; Flavonoids; Mice; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1997
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).
    The Biochemical journal, 2003, Sep-15, Volume: 374, Issue:Pt 3

    Topics: Acetates; Animals; Casein Kinase II; Cell Line; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Jurkat Cells; Molecular Structure; Plant Proteins; Protein Serine-Threonine Kinases; Protein Structure, Quaternary; Quinazolines; Rats; Zea mays

2003
A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors.
    Journal of medicinal chemistry, 2004, Oct-21, Volume: 47, Issue:22

    Topics: Adenosine Triphosphate; Animals; Antimalarials; Binding Sites; Cyclin-Dependent Kinases; Databases, Factual; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Plasmodium falciparum; Protein Kinases; Protozoan Proteins; Quantitative Structure-Activity Relationship

2004
Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.
    Journal of medicinal chemistry, 2005, Dec-01, Volume: 48, Issue:24

    Topics: Antineoplastic Agents; Crystallization; Crystallography, X-Ray; Flavonoids; Humans; Imidazoles; Indoles; Maleimides; Models, Molecular; Molecular Structure; Moloney murine leukemia virus; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-pim-1; Proviruses; Pyrazoles; Pyridazines; Pyrimidines; Structure-Activity Relationship

2005
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Characterization of receptor tyrosine-specific protein kinases by the use of inhibitors. Staurosporine is a 100-times more potent inhibitor of insulin receptor than IGF-I receptor.
    Biochemical and biophysical research communications, 1988, Dec-30, Volume: 157, Issue:3

    Topics: Adenosine Triphosphate; Alkaloids; Binding, Competitive; Chamomile; Female; Flavonoids; Humans; Kaempferols; Molecular Structure; Oils, Volatile; Phosphorylation; Placenta; Plants, Medicinal; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Somatomedin; Staurosporine

1988
Streptomyces sp. BV410 isolate from chamomile rhizosphere soil efficiently produces staurosporine with antifungal and antiangiogenic properties.
    MicrobiologyOpen, 2020, Volume: 9, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antifungal Agents; Chamomile; Phylogeny; Rhizosphere; RNA, Ribosomal, 16S; Secondary Metabolism; Staurosporine; Streptomyces; Zebrafish

2020